Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS012527
(VTE_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Venous thromboembolism venous thromboembolism 516,802
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012527/ScoringFiles/PGS012527.txt.gz
PGS012526
(BMI_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Body mass index (BMI) body mass index 434,712
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012526/ScoringFiles/PGS012526.txt.gz
PGS012525
(LDL_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 LDL cholesterol low density lipoprotein cholesterol measurement 521,113
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012525/ScoringFiles/PGS012525.txt.gz
PGS012524
(HDL_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 HDL cholesterol high density lipoprotein cholesterol measurement 524,956
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012524/ScoringFiles/PGS012524.txt.gz
PGS012523
(DBP_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Diastolic blood pressure diastolic blood pressure 574,294
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012523/ScoringFiles/PGS012523.txt.gz
PGS012522
(SBP_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Systolic blood pressure systolic blood pressure 574,384
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012522/ScoringFiles/PGS012522.txt.gz
PGS012521
(OSA_bmi_adj)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea (adjusted for BMI) obstructive sleep apnea syndrome 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012521/ScoringFiles/PGS012521.txt.gz
PGS012520
(OSA_bmi_unadj)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea obstructive sleep apnea syndrome 17
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012520/ScoringFiles/PGS012520.txt.gz
PGS012519
(VTE)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Venous thromboembolism venous thromboembolism 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012519/ScoringFiles/PGS012519.txt.gz
PGS012518
(BMI)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Body mass index (BMI) body mass index 1,440
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012518/ScoringFiles/PGS012518.txt.gz
PGS012517
(LDL)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 LDL cholesterol low density lipoprotein cholesterol measurement 245
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012517/ScoringFiles/PGS012517.txt.gz
PGS012516
(HDL)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 HDL cholesterol high density lipoprotein cholesterol measurement 482
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012516/ScoringFiles/PGS012516.txt.gz
PGS012515
(DBP)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Diastolic blood pressure diastolic blood pressure 98
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012515/ScoringFiles/PGS012515.txt.gz
PGS012514
(SBP)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Systolic blood pressure systolic blood pressure 107
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012514/ScoringFiles/PGS012514.txt.gz
PGS012513
(eoe)
 PGP000785 |
Trimarchi MP et al. J Allergy Clin Immunol (2026)
 Eosinophilic esophagitis (EOE) eosinophilic esophagitis 1,039,900
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012513/ScoringFiles/PGS012513.txt.gz
PGS005402
(PRS121)
 PGP000783 |
Chen H et al. Genome Med (2026)
 Colorectal cancer colorectal cancer 121
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005402/ScoringFiles/PGS005402.txt.gz
PGS005400
(T1D_PRS_female)
 PGP000781 |
Qu HQ et al. Diabetes Res Clin Pract (2026)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 128,279
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005400/ScoringFiles/PGS005400.txt.gz
PGS005399
(T1D_PRS_male)
 PGP000781 |
Qu HQ et al. Diabetes Res Clin Pract (2026)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 264,227
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005399/ScoringFiles/PGS005399.txt.gz
PGS005398
(T1D_PRS_combined)
 PGP000781 |
Qu HQ et al. Diabetes Res Clin Pract (2026)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 645,391
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005398/ScoringFiles/PGS005398.txt.gz
PGS005397
(Genome_wide_PRS)
 PGP000780 |
Boumtje V et al. Transl Oncol (2026)
 Lung cancer lung cancer 1,022,277
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005397/ScoringFiles/PGS005397.txt.gz
PGS005393
(PGS_SEXUAL_ASSAULT_PTSD)
 PGP000778 |
Bugiga AVG et al. Braz J Psychiatry (2024)
 Post-traumatic stress disorder post-traumatic stress disorder 53,705
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005393/ScoringFiles/PGS005393.txt.gz
PGS005392
(Q-PGS4_r0.2_p5e4)
 PGP000777 |
Aliyu U et al. Front Endocrinol (Lausanne) (2024)
 HOMA2-IR HOMA-IR 1,414
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005392/ScoringFiles/PGS005392.txt.gz
PGS005391
(ADRD_consensus_no_biobank_score)
 PGP000776 |
EADB et al. Nat Genet (2026)
 Alzheimer's disease Alzheimer disease 65
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005391/ScoringFiles/PGS005391.txt.gz
PGS005390
(ADRD_consensus_no_proxy_score)
 PGP000776 |
EADB et al. Nat Genet (2026)
 Alzheimer's disease Alzheimer disease 91
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005390/ScoringFiles/PGS005390.txt.gz
PGS005389
(ADRD_consensus_main_score)
 PGP000776 |
EADB et al. Nat Genet (2026)
 Alzheimer's disease Alzheimer disease 115
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005389/ScoringFiles/PGS005389.txt.gz
PGS005388
(PAF_PRS)
 PGP000775 |
Shiomi M et al. PLoS One (2026)
 Paroxysmal atrial fibrillation Paroxysmal atrial fibrillation 122
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005388/ScoringFiles/PGS005388.txt.gz
PGS005387
(TNBC_162_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 162
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005387/ScoringFiles/PGS005387.txt.gz
PGS005386
(TNBC_162_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 162
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005386/ScoringFiles/PGS005386.txt.gz
PGS005385
(TNBC_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 37,226
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005385/ScoringFiles/PGS005385.txt.gz
PGS005384
(TNBC_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 554,959
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005384/ScoringFiles/PGS005384.txt.gz
PGS005383
(Erneg_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor negative breast cancer estrogen-receptor negative breast cancer 37,783
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005383/ScoringFiles/PGS005383.txt.gz
PGS005382
(Erneg_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor negative breast cancer estrogen-receptor negative breast cancer 2,005,141
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005382/ScoringFiles/PGS005382.txt.gz
PGS005381
(Erpos_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor positive breast cancer estrogen-receptor positive breast cancer 109,933
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005381/ScoringFiles/PGS005381.txt.gz
PGS005380
(Erpos_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor positive breast cancer estrogen-receptor positive breast cancer 592,247
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005380/ScoringFiles/PGS005380.txt.gz
PGS005379
(Overall_Prop_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Breast cancer breast carcinoma 175,173
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005379/ScoringFiles/PGS005379.txt.gz
PGS005378
(Overall_Prop_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Breast cancer breast carcinoma 2,321,840
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005378/ScoringFiles/PGS005378.txt.gz
PGS005377
(DPRISM_T2DPRS_trainedforSAS_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,327,177
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005377/ScoringFiles/PGS005377.txt.gz
PGS005376
(DPRISM_T2DPRS_trainedforSAS_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,386,504
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005376/ScoringFiles/PGS005376.txt.gz
PGS005375
(DPRISM_T2DPRS_trainedforSAS_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 983,905
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005375/ScoringFiles/PGS005375.txt.gz
PGS005374
(DPRISM_T2DPRS_trainedforSAS_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,419,570
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005374/ScoringFiles/PGS005374.txt.gz
PGS005373
(DPRISM_T2DPRS_trainedforSAS_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,344,157
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005373/ScoringFiles/PGS005373.txt.gz
PGS005372
(DPRISM_T2DPRS_trainedforEUR_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,165
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005372/ScoringFiles/PGS005372.txt.gz
PGS005371
(DPRISM_T2DPRS_trainedforEUR_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,444,665
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005371/ScoringFiles/PGS005371.txt.gz
PGS005370
(DPRISM_T2DPRS_trainedforEUR_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 942,728
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005370/ScoringFiles/PGS005370.txt.gz
PGS005369
(DPRISM_T2DPRS_trainedforEUR_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,388,666
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005369/ScoringFiles/PGS005369.txt.gz
PGS005368
(DPRISM_T2DPRS_trainedforEUR_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,298,374
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005368/ScoringFiles/PGS005368.txt.gz
PGS005367
(DPRISM_T2DPRS_trainedforEAS_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 976,035
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005367/ScoringFiles/PGS005367.txt.gz
PGS005366
(DPRISM_T2DPRS_trainedforEAS_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 929,716
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005366/ScoringFiles/PGS005366.txt.gz
PGS005365
(DPRISM_T2DPRS_trainedforEAS_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,009,254
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005365/ScoringFiles/PGS005365.txt.gz
PGS005364
(DPRISM_T2DPRS_trainedforEAS_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 980,079
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005364/ScoringFiles/PGS005364.txt.gz
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