Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS005157
(Type 2 diabetes (CT-SLEB; EAS+EUR))
PGP000704 |
Jung HU et al. Commun Biol (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 502,115
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005157/ScoringFiles/PGS005157.txt.gz
PGS005242
(T2D_PRS_PRS_CSx_META_T)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,036
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005242/ScoringFiles/PGS005242.txt.gz
PGS005243
(T2D_PRS_PRS_CSx_META_F_AFR)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,183,017
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005243/ScoringFiles/PGS005243.txt.gz
PGS005244
(T2D_PRS_PRS_CSx_META_F_AMR)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 960,470
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005244/ScoringFiles/PGS005244.txt.gz
PGS005245
(T2D_PRS_PRS_CSx_META_F_EAS)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,021,829
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005245/ScoringFiles/PGS005245.txt.gz
PGS005246
(T2D_PRS_PRS_CSx_META_F_EUR)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,111,848
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005246/ScoringFiles/PGS005246.txt.gz
PGS005247
(T2D_PRS_PRS_CSx_META_F_SAS)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,126,657
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005247/ScoringFiles/PGS005247.txt.gz
PGS005314
(T2D_PRS_AA)
PGP000762 |
Irvin MR et al. Diabetes (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,181,614
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005314/ScoringFiles/PGS005314.txt.gz
PGS005333
(D_MetPRS_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005333/ScoringFiles/PGS005333.txt.gz
PGS005334
(D_MetPRS_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005334/ScoringFiles/PGS005334.txt.gz
PGS005335
(D_MetPRS_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005335/ScoringFiles/PGS005335.txt.gz
PGS005336
(D_MetPRS_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005336/ScoringFiles/PGS005336.txt.gz
PGS005341
(D_MetPRS_noUKB_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005341/ScoringFiles/PGS005341.txt.gz
PGS005342
(D_MetPRS_noUKB_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005342/ScoringFiles/PGS005342.txt.gz
PGS005343
(D_MetPRS_noUKB_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005343/ScoringFiles/PGS005343.txt.gz
PGS005344
(D_MetPRS_noUKB_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005344/ScoringFiles/PGS005344.txt.gz
PGS005353
(DPRISM_T2DPRS_trainedforAFR_AFRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 2,325,981
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005353/ScoringFiles/PGS005353.txt.gz
PGS005354
(DPRISM_T2DPRS_trainedforAFR_AMRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,642,045
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005354/ScoringFiles/PGS005354.txt.gz
PGS005355
(DPRISM_T2DPRS_trainedforAFR_EASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 981,210
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005355/ScoringFiles/PGS005355.txt.gz
PGS005356
(DPRISM_T2DPRS_trainedforAFR_EURweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,333,977
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005356/ScoringFiles/PGS005356.txt.gz
PGS005357
(DPRISM_T2DPRS_trainedforAFR_SASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,227
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005357/ScoringFiles/PGS005357.txt.gz
PGS005358
(DPRISM_T2DPRS_trainedforAMR_AFRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,322,950
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005358/ScoringFiles/PGS005358.txt.gz
PGS005359
(DPRISM_T2DPRS_trainedforAMR_AMRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,427,746
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005359/ScoringFiles/PGS005359.txt.gz
PGS005360
(DPRISM_T2DPRS_trainedforAMR_EASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 941,393
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005360/ScoringFiles/PGS005360.txt.gz
PGS005361
(DPRISM_T2DPRS_trainedforAMR_EURweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,262,174
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005361/ScoringFiles/PGS005361.txt.gz
PGS005362
(DPRISM_T2DPRS_trainedforAMR_SASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,191,714
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005362/ScoringFiles/PGS005362.txt.gz
PGS005363
(DPRISM_T2DPRS_trainedforEAS_AFRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 946,015
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005363/ScoringFiles/PGS005363.txt.gz
PGS005364
(DPRISM_T2DPRS_trainedforEAS_AMRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 980,079
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005364/ScoringFiles/PGS005364.txt.gz
PGS005365
(DPRISM_T2DPRS_trainedforEAS_EASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,009,254
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005365/ScoringFiles/PGS005365.txt.gz
PGS005366
(DPRISM_T2DPRS_trainedforEAS_EURweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 929,716
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005366/ScoringFiles/PGS005366.txt.gz
PGS005367
(DPRISM_T2DPRS_trainedforEAS_SASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 976,035
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005367/ScoringFiles/PGS005367.txt.gz
PGS005368
(DPRISM_T2DPRS_trainedforEUR_AFRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,298,374
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005368/ScoringFiles/PGS005368.txt.gz
PGS005369
(DPRISM_T2DPRS_trainedforEUR_AMRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,388,666
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005369/ScoringFiles/PGS005369.txt.gz
PGS005370
(DPRISM_T2DPRS_trainedforEUR_EASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 942,728
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005370/ScoringFiles/PGS005370.txt.gz
PGS005371
(DPRISM_T2DPRS_trainedforEUR_EURweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,444,665
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005371/ScoringFiles/PGS005371.txt.gz
PGS005372
(DPRISM_T2DPRS_trainedforEUR_SASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,165
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005372/ScoringFiles/PGS005372.txt.gz
PGS005373
(DPRISM_T2DPRS_trainedforSAS_AFRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,344,157
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005373/ScoringFiles/PGS005373.txt.gz
PGS005374
(DPRISM_T2DPRS_trainedforSAS_AMRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,419,570
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005374/ScoringFiles/PGS005374.txt.gz
PGS005375
(DPRISM_T2DPRS_trainedforSAS_EASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 983,905
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005375/ScoringFiles/PGS005375.txt.gz
PGS005376
(DPRISM_T2DPRS_trainedforSAS_EURweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,386,504
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005376/ScoringFiles/PGS005376.txt.gz
PGS005377
(DPRISM_T2DPRS_trainedforSAS_SASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,327,177
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005377/ScoringFiles/PGS005377.txt.gz
PGS012554
(GRS_T2D)
PGP000797 |
Yang R et al. BMC Med (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 424
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012554/ScoringFiles/PGS012554.txt.gz
PGS005021
(Phe_250_2_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005021/ScoringFiles/PGS005021.txt.gz
PGS005022
(Phe_250_2_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005022/ScoringFiles/PGS005022.txt.gz
PGS005023
(Phe_250_2_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005023/ScoringFiles/PGS005023.txt.gz
PGS005024
(Phe_250_2_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005024/ScoringFiles/PGS005024.txt.gz
PGS005025
(Phe_250_2_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005025/ScoringFiles/PGS005025.txt.gz
PGS005026
(Phe_250_2_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005026/ScoringFiles/PGS005026.txt.gz
PGS005027
(Phe_250_2_prscs_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005027/ScoringFiles/PGS005027.txt.gz
PGS005028
(Phe_250_2_prscs_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005028/ScoringFiles/PGS005028.txt.gz