Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003832
(TC_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 1,468,958
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003832/ScoringFiles/PGS003832.txt.gz
PGS004749
(creatinine_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Serum creatinine serum creatinine amount 1,469,062
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004749/ScoringFiles/PGS004749.txt.gz
PGS004678
(TC_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Total cholesterol total cholesterol measurement 1,471,975
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004678/ScoringFiles/PGS004678.txt.gz
PGS003780
(HDL_SAS_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,473,121
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003780/ScoringFiles/PGS003780.txt.gz
PGS003781
(HDL_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,473,121
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003781/ScoringFiles/PGS003781.txt.gz
PGS004633
(HDL_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,476,939
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004633/ScoringFiles/PGS004633.txt.gz
PGS000883
(eGFR_LDpredPRS)
 PGP000229 |
Yu Z et al. J Am Soc Nephrol (2021)
 Estimated glomerular filtration rate glomerular filtration rate 1,477,661
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000883/ScoringFiles/PGS000883.txt.gz
PGS003768
(HDL_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,489,018
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003768/ScoringFiles/PGS003768.txt.gz
PGS003819
(TC_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 1,490,151
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003819/ScoringFiles/PGS003819.txt.gz
PGS003785
(LDL_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,490,736
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003785/ScoringFiles/PGS003785.txt.gz
PGS003802
(logTG_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,492,288
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003802/ScoringFiles/PGS003802.txt.gz
PGS003377
(eGFRldpred_PGS)
 PGP000411 |
Steinbrenner I et al. Kidney Int (2022)
 Estimated glomerular filtration rate glomerular filtration rate 1,496,254
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003377/ScoringFiles/PGS003377.txt.gz
PGS004740
(BUN_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Urea urea measurement 1,499,858
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004740/ScoringFiles/PGS004740.txt.gz
PGS004742
(BUN_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Urea urea measurement 1,499,858
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004742/ScoringFiles/PGS004742.txt.gz
PGS003814
(logTG_SAS_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,507,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003814/ScoringFiles/PGS003814.txt.gz
PGS003815
(logTG_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,507,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003815/ScoringFiles/PGS003815.txt.gz
PGS003797
(LDL_SAS_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,507,815
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003797/ScoringFiles/PGS003797.txt.gz
PGS003798
(LDL_SAS_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,507,815
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003798/ScoringFiles/PGS003798.txt.gz
PGS004663
(logTG_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Log triglycerides triglyceride measurement 1,510,317
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004663/ScoringFiles/PGS004663.txt.gz
PGS004648
(LDL_SAS_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,511,084
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004648/ScoringFiles/PGS004648.txt.gz
PGS003355
(1MH_CAD_PRS_2015_Ldpred)
 PGP000409 |
Aragam KG et al. Nat Genet (2022)
 Coronary artery disease coronary artery disease 1,532,758
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003355/ScoringFiles/PGS003355.txt.gz
PGS004759
(depression_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Depression major depressive disorder 1,538,576
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004759/ScoringFiles/PGS004759.txt.gz
PGS004729
(Basophils_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Basophil count basophil count 1,538,675
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004729/ScoringFiles/PGS004729.txt.gz
PGS004824
(RBC_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Red blood cell count erythrocyte count 1,542,933
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004824/ScoringFiles/PGS004824.txt.gz
PGS004768
(gout_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Gout gout 1,580,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004768/ScoringFiles/PGS004768.txt.gz
PGS005224
(F3_Frailty)
 PGP000735 |
Foote IF et al. Nat Genet (2025)
 Factor 3 (multimorbidity) of frailty frailty measurement 1,588,232
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005224/ScoringFiles/PGS005224.txt.gz
PGS004782
(height_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Height body height 1,612,712
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004782/ScoringFiles/PGS004782.txt.gz
PGS002987
(ExPRSweb_Height_GIANT-Yang2012-height_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Height body height 1,661,426
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002987/ScoringFiles/PGS002987.txt.gz
PGS002877
(ExPRSweb_CRP_prot-a-670_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 1,662,602
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002877/ScoringFiles/PGS002877.txt.gz
PGS003770
(HDL_AFR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,678,653
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003770/ScoringFiles/PGS003770.txt.gz
PGS003771
(HDL_AFR_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,678,653
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003771/ScoringFiles/PGS003771.txt.gz
PGS003804
(logTG_AFR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,678,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003804/ScoringFiles/PGS003804.txt.gz
PGS003805
(logTG_AFR_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 1,678,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003805/ScoringFiles/PGS003805.txt.gz
PGS003787
(LDL_AFR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,679,610
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003787/ScoringFiles/PGS003787.txt.gz
PGS003788
(LDL_AFR_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,679,610
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003788/ScoringFiles/PGS003788.txt.gz
PGS004653
(logTG_AFR_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Log triglycerides triglyceride measurement 1,682,390
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004653/ScoringFiles/PGS004653.txt.gz
PGS004623
(HDL_AFR_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,683,003
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004623/ScoringFiles/PGS004623.txt.gz
PGS004638
(LDL_AFR_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,683,941
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004638/ScoringFiles/PGS004638.txt.gz
PGS003821
(TC_AFR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 1,687,775
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003821/ScoringFiles/PGS003821.txt.gz
PGS003822
(TC_AFR_weighted_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 1,687,775
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003822/ScoringFiles/PGS003822.txt.gz
PGS004624
(HDL_AFR_PROSPER)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,688,569
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004624/ScoringFiles/PGS004624.txt.gz
PGS004668
(TC_AFR_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Total cholesterol total cholesterol measurement 1,691,065
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004668/ScoringFiles/PGS004668.txt.gz
PGS004764
(Eosinophils_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Eosinophil count eosinophil count 1,698,846
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004764/ScoringFiles/PGS004764.txt.gz
PGS004712
(ALP_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Alkaline phosphatase alkaline phosphatase measurement 1,704,295
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004712/ScoringFiles/PGS004712.txt.gz
PGS004714
(ALP_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Alkaline phosphatase alkaline phosphatase measurement 1,704,295
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004714/ScoringFiles/PGS004714.txt.gz
PGS001800
(PRS_FEV1)
 PGP000264 |
Moll M et al. Lancet Respir Med (2020)
 Forced expiratory volume (FEV1) forced expiratory volume 1,713,430
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001800/ScoringFiles/PGS001800.txt.gz
PGS005226
(F5_Frailty)
 PGP000735 |
Foote IF et al. Nat Genet (2025)
 Factor 5 (poorer cognition) of frailty frailty measurement 1,715,891
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005226/ScoringFiles/PGS005226.txt.gz
PGS005223
(F2_Frailty)
 PGP000735 |
Foote IF et al. Nat Genet (2025)
 Factor 2 (unhealthy lifestyle) of frailty frailty measurement 1,719,220
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005223/ScoringFiles/PGS005223.txt.gz
PGS004659
(logTG_EAS_PROSPER)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Log triglycerides triglyceride measurement 1,722,077
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004659/ScoringFiles/PGS004659.txt.gz
PGS005227
(F6_Frailty)
 PGP000735 |
Foote IF et al. Nat Genet (2025)
 Factor 6 (disability) of frailty frailty measurement 1,726,064
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005227/ScoringFiles/PGS005227.txt.gz
Showing 4901 to 4950 of 5221 rows