Trait: cancer

Experimental Factor Ontology (EFO) Information
Identifier EFO_0000311
Description A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. [NCIT: C9305]
Trait category
Cancer
Synonyms 16 synonyms
  • CA
  • Malignant Neoplasm
  • cancer
  • cell type cancer
  • malignancy
  • malignant Growth
  • malignant neoplasia
  • malignant neoplasm
  • malignant neoplasm (disease)
  • malignant neoplastic disease
  • malignant tumor
  • malignant tumour
  • neoplasm (disease), malignant
  • neoplasm, malignant
  • organ system cancer
  • primary cancer
Mapped term(s) 18 mapped terms
  • COHD:443392
  • DOID:0050686
  • DOID:0050687
  • DOID:162
  • GARD:0011960
  • ICD10:C80
  • ICD10:C80.1
  • ICD9:195.8
  • ICD9:199
  • ICD9:199.1
  • ICDO:8000/3
  • MONDO:0004992
  • NCIT:C9305
  • NCIt:C9305
  • NIFSTD:birnlex_406
  • ONCOTREE:MT
  • SCTID:363346000
  • UMLS:C0006826
Child trait(s) 54 child traits

Associated Polygenic Score(s)

Note: This table shows all PGS for "cancer" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score (PGS) ID PGS Name PGS Publication (PGP) ID Reported Trait Mapped Trait(s) (Ontology) Number of Variants PGS Scoring File (FTP Link)
PGS000001 PRS77_BC PGP000001 Mavaddat N et al. J Natl Cancer Inst (2015) Breast Cancer breast carcinoma 77 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000001/ScoringFiles/PGS000001.txt.gz
PGS000002 PRS77_ERpos PGP000001 Mavaddat N et al. J Natl Cancer Inst (2015) ER-positive Breast Cancer estrogen-receptor positive breast cancer 77 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000002/ScoringFiles/PGS000002.txt.gz
PGS000003 PRS77_ERneg PGP000001 Mavaddat N et al. J Natl Cancer Inst (2015) ER-negative Breast Cancer estrogen-receptor negative breast cancer 77 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000003/ScoringFiles/PGS000003.txt.gz
PGS000004 PRS313_BC PGP000002 Mavaddat N et al. Am J Hum Genet (2018) Breast Cancer breast carcinoma 313 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000004/ScoringFiles/PGS000004.txt.gz
PGS000005 PRS313_ERpos PGP000002 Mavaddat N et al. Am J Hum Genet (2018) ER-positive Breast Cancer estrogen-receptor positive breast cancer 313 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000005/ScoringFiles/PGS000005.txt.gz
PGS000006 PRS313_ERneg PGP000002 Mavaddat N et al. Am J Hum Genet (2018) ER-negative Breast Cancer estrogen-receptor negative breast cancer 313 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000006/ScoringFiles/PGS000006.txt.gz
PGS000007 PRS3820_BC PGP000002 Mavaddat N et al. Am J Hum Genet (2018) Breast Cancer breast carcinoma 3,820 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000007/ScoringFiles/PGS000007.txt.gz
PGS000008 PRS3820_ERpos PGP000002 Mavaddat N et al. Am J Hum Genet (2018) ER-positive Breast Cancer estrogen-receptor positive breast cancer 3,820 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000008/ScoringFiles/PGS000008.txt.gz
PGS000009 PRS3820_ERneg PGP000002 Mavaddat N et al. Am J Hum Genet (2018) ER-negative Breast Cancer estrogen-receptor negative breast cancer 3,820 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000009/ScoringFiles/PGS000009.txt.gz
PGS000015 GPS_BC PGP000006 Khera AV et al. Nat Genet (2018) Breast cancer breast carcinoma 5,218 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000015/ScoringFiles/PGS000015.txt.gz - Check Terms/Licenses
PGS000028 PRS PGP000018 Shieh Y et al. Breast Cancer Res Treat (2016) Breast cancer breast carcinoma 83 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000028/ScoringFiles/PGS000028.txt.gz
PGS000029 PRS_AS PGP000018 Shieh Y et al. Breast Cancer Res Treat (2016) Breast cancer breast carcinoma 76 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000029/ScoringFiles/PGS000029.txt.gz
PGS000030 PrCa PGP000019 Schumacher FR et al. Nat Genet (2018) Prostate cancer prostate carcinoma 147 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000030/ScoringFiles/PGS000030.txt.gz
PGS000044 PrCa66 PGP000031 Pashayan N et al. Br J Cancer (2015) Prostate cancer prostate carcinoma 66 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000044/ScoringFiles/PGS000044.txt.gz
PGS000045 BCPRS_Overall PGP000033 Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Breast cancer breast carcinoma 88 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000045/ScoringFiles/PGS000045.txt.gz
PGS000046 BCPRS_ER+ PGP000033 Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Estrogen receptor [ER]-positive breast cancer estrogen-receptor positive breast cancer 87 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000046/ScoringFiles/PGS000046.txt.gz
PGS000047 BCPRS_ER- PGP000033 Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Estrogen receptor [ER]-negative breast cancer estrogen-receptor negative breast cancer 53 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000047/ScoringFiles/PGS000047.txt.gz
PGS000048 OCPRS_Overall PGP000033 Kuchenbaecker KB et al. J Natl Cancer Inst (2017) Ovarian cancer ovarian carcinoma 17 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000048/ScoringFiles/PGS000048.txt.gz
PGS000049 PRS103_PrCa PGP000034 Lecarpentier J et al. J Clin Oncol (2017) Prostate Cancer prostate carcinoma 103 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000049/ScoringFiles/PGS000049.txt.gz
PGS000050 PRS44 PGP000035 Wen W et al. Breast Cancer Res (2016) Breast cancer breast carcinoma 44 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000050/ScoringFiles/PGS000050.txt.gz
PGS000051 PRS67 PGP000036 Zhang X et al. PLoS Med (2018) Breast Cancer breast carcinoma 67 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000051/ScoringFiles/PGS000051.txt.gz
PGS000052 sPRS161 PGP000037 Lakeman IMM et al. J Med Genet (2019) Breast cancer breast carcinoma 161 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000052/ScoringFiles/PGS000052.txt.gz
PGS000055 PRS_CRC PGP000040 Schmit SL et al. J Natl Cancer Inst (2019) Colorectal cancer colorectal cancer 76 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000055/ScoringFiles/PGS000055.txt.gz
PGS000067 PCa_PHS PGP000047 Seibert TM et al. BMJ (2018) Prostate cancer prostate carcinoma 54 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000067/ScoringFiles/PGS000067.txt.gz
PGS000068 PRS_EOC PGP000048 Yang X et al. J Med Genet (2018) Epithelial ovarian cancer ovarian carcinoma 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000068/ScoringFiles/PGS000068.txt.gz
PGS000069 PRS_sEOC PGP000048 Yang X et al. J Med Genet (2018) Serous epithelial ovarian cancer ovarian serous carcinoma 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000069/ScoringFiles/PGS000069.txt.gz
PGS000070 PRS_LC_C PGP000049 Dai J et al. Lancet Respir Med (2019) Lung cancer lung adenocarcinoma 19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000070/ScoringFiles/PGS000070.txt.gz
PGS000071 CC_Bladder PGP000050 Graff RE et al. bioRxiv (2020) Pre Bladder cancer bladder carcinoma 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000071/ScoringFiles/PGS000071.txt.gz
PGS000072 CC_Breast PGP000050 Graff RE et al. bioRxiv (2020) Pre Breast cancer breast carcinoma 187 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000072/ScoringFiles/PGS000072.txt.gz
PGS000073 CC_Cervix PGP000050 Graff RE et al. bioRxiv (2020) Pre Cervical cancer cervical carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000073/ScoringFiles/PGS000073.txt.gz
PGS000074 CC_Colorectal PGP000050 Graff RE et al. bioRxiv (2020) Pre Colorectal cancer colorectal cancer 103 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000074/ScoringFiles/PGS000074.txt.gz
PGS000075 CC_Endo PGP000050 Graff RE et al. bioRxiv (2020) Pre Endometrial cancer endometrial carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000075/ScoringFiles/PGS000075.txt.gz
PGS000076 CC_Kidney PGP000050 Graff RE et al. bioRxiv (2020) Pre Kidney cancer renal cell carcinoma 19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000076/ScoringFiles/PGS000076.txt.gz
PGS000077 CC_LL PGP000050 Graff RE et al. bioRxiv (2020) Pre Lymphocytic leukemia lymphoid leukemia 75 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000077/ScoringFiles/PGS000077.txt.gz
PGS000078 CC_Lung PGP000050 Graff RE et al. bioRxiv (2020) Pre Lung cancer lung carcinoma 109 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000078/ScoringFiles/PGS000078.txt.gz
PGS000079 CC_Melanoma PGP000050 Graff RE et al. bioRxiv (2020) Pre Melanoma melanoma 24 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000079/ScoringFiles/PGS000079.txt.gz
PGS000080 CC_NHL PGP000050 Graff RE et al. bioRxiv (2020) Pre Non-Hodgkin's lymphoma non-Hodgkins lymphoma 19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000080/ScoringFiles/PGS000080.txt.gz
PGS000081 CC_Oral PGP000050 Graff RE et al. bioRxiv (2020) Pre Oral cavity and pharyngeal cancers carcinoma of pharynx
oral cavity cancer
14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000081/ScoringFiles/PGS000081.txt.gz
PGS000082 CC_Ovary PGP000050 Graff RE et al. bioRxiv (2020) Pre Ovarian cancer ovarian carcinoma 36 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000082/ScoringFiles/PGS000082.txt.gz
PGS000083 CC_Pancreas PGP000050 Graff RE et al. bioRxiv (2020) Pre Pancreatic cancer pancreatic carcinoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000083/ScoringFiles/PGS000083.txt.gz
PGS000084 CC_Prostate PGP000050 Graff RE et al. bioRxiv (2020) Pre Prostate cancer prostate carcinoma 161 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000084/ScoringFiles/PGS000084.txt.gz
PGS000085 CC_Stomach PGP000050 Graff RE et al. bioRxiv (2020) Pre Esophageal and stomach cancers gastric carcinoma
Barrett's esophagus
13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000085/ScoringFiles/PGS000085.txt.gz
PGS000086 CC_Testis PGP000050 Graff RE et al. bioRxiv (2020) Pre Testicular cancer testicular carcinoma
Testicular Germ Cell Tumor
52 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000086/ScoringFiles/PGS000086.txt.gz
PGS000087 CC_Thyroid PGP000050 Graff RE et al. bioRxiv (2020) Pre Thyroid cancer thyroid carcinoma 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000087/ScoringFiles/PGS000087.txt.gz
PGS000118 MEL29 PGP000055 Fritsche LG et al. PLoS Genet (2019) Melanoma melanoma 29 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000118/ScoringFiles/PGS000118.txt.gz
PGS000119 BCC32 PGP000055 Fritsche LG et al. PLoS Genet (2019) Basal cell carcinoma basal cell carcinoma 32 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000119/ScoringFiles/PGS000119.txt.gz
PGS000120 SCC10 PGP000055 Fritsche LG et al. PLoS Genet (2019) Squamous cell carcinoma squamous cell carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000120/ScoringFiles/PGS000120.txt.gz
PGS000146 CRC_GRS_27 PGP000069 Hsu L et al. Gastroenterology (2015) Colorectal cancer risk colorectal cancer 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000146/ScoringFiles/PGS000146.txt.gz
PGS000147 CRC21 PGP000070 Ibáñez-Sanz G et al. Sci Rep (2017) Colorectal cancer colorectal cancer 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000147/ScoringFiles/PGS000147.txt.gz
PGS000148 CRC63 PGP000071 Jeon J et al. Gastroenterology (2018) Colorectal cancer colorectal cancer 63 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000148/ScoringFiles/PGS000148.txt.gz
PGS000149 CRC41 PGP000072 Smith T et al. Br J Cancer (2018) Colorectal cancer colorectal cancer 41 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000149/ScoringFiles/PGS000149.txt.gz
PGS000150 GRS48 PGP000073 Weigl K et al. Gastroenterology (2018) Colorectal cancer colorectal cancer 48 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000150/ScoringFiles/PGS000150.txt.gz
PGS000151 SC_GRS PGP000074 Xin J et al. Gene (2018) Colorectal cancer colorectal cancer 14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000151/ScoringFiles/PGS000151.txt.gz
PGS000152 cGRS_Bladder PGP000075 Shi Z et al. Cancer Med (2019) Bladder cancer bladder carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000152/ScoringFiles/PGS000152.txt.gz
PGS000153 cGRS_Breast PGP000075 Shi Z et al. Cancer Med (2019) Breast cancer breast carcinoma 66 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000153/ScoringFiles/PGS000153.txt.gz
PGS000154 cGRS_Colorectal PGP000075 Shi Z et al. Cancer Med (2019) Colorectal cancer colorectal cancer 30 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000154/ScoringFiles/PGS000154.txt.gz
PGS000156 cGRS_Lung PGP000075 Shi Z et al. Cancer Med (2019) Lung cancer lung carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000156/ScoringFiles/PGS000156.txt.gz
PGS000157 cGRS_Melanoma PGP000075 Shi Z et al. Cancer Med (2019) Melanoma melanoma 17 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000157/ScoringFiles/PGS000157.txt.gz
PGS000158 cGRS_Ovarian PGP000075 Shi Z et al. Cancer Med (2019) Ovarian cancer ovarian carcinoma 11 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000158/ScoringFiles/PGS000158.txt.gz
PGS000159 cGRS_Pancreatic PGP000075 Shi Z et al. Cancer Med (2019) Pancreatic cancer pancreatic carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000159/ScoringFiles/PGS000159.txt.gz
PGS000160 cGRS_Prostate PGP000075 Shi Z et al. Cancer Med (2019) Prostate cancer prostate carcinoma 79 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000160/ScoringFiles/PGS000160.txt.gz
PGS000161 cGRS_Renal PGP000075 Shi Z et al. Cancer Med (2019) Renal cancer renal carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000161/ScoringFiles/PGS000161.txt.gz
PGS000162 cGRS_Thyroid PGP000075 Shi Z et al. Cancer Med (2019) Thyroid cancer thyroid carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000162/ScoringFiles/PGS000162.txt.gz
PGS000207 TC10_Ohio PGP000085 Liyanarachchi S et al. Proc Natl Acad Sci U S A (2020) Thyroid cancer thyroid carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000207/ScoringFiles/PGS000207.txt.gz
PGS000208 TC10_Iceland PGP000085 Liyanarachchi S et al. Proc Natl Acad Sci U S A (2020) Thyroid cancer thyroid carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000208/ScoringFiles/PGS000208.txt.gz
PGS000209 TC10_UKB PGP000085 Liyanarachchi S et al. Proc Natl Acad Sci U S A (2020) Thyroid cancer thyroid carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000209/ScoringFiles/PGS000209.txt.gz
PGS000212 PRS330_LumA PGP000088 Zhang H et al. Nat Genet (2020) Breast cancer intrinsic-like subtype (luminal A-like) luminal A breast carcinoma 330 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000212/ScoringFiles/PGS000212.txt.gz
PGS000213 PRS330_LumBHER2neg PGP000088 Zhang H et al. Nat Genet (2020) Breast cancer intrinsic-like subtype (luminal B/HER2-negative-like) Her2-receptor negative breast cancer 330 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000213/ScoringFiles/PGS000213.txt.gz
PGS000214 PRS330_LumB PGP000088 Zhang H et al. Nat Genet (2020) Breast cancer intrinsic-like subtype (luminal B-like) luminal B breast carcinoma 330 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000214/ScoringFiles/PGS000214.txt.gz
PGS000215 PRS330_HER2 PGP000088 Zhang H et al. Nat Genet (2020) Breast cancer intrinsic-like subtype (HER2-enriched-like) HER2 Positive Breast Carcinoma 330 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000215/ScoringFiles/PGS000215.txt.gz
PGS000216 PRS330_TN PGP000088 Zhang H et al. Nat Genet (2020) Breast cancer intrinsic-like subtype (triple negative) triple-negative breast cancer 330 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000216/ScoringFiles/PGS000216.txt.gz
PGS000317 PRS180 PGP000094 Shieh Y et al. J Natl Cancer Inst (2020) Breast cancer breast carcinoma 180 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000317/ScoringFiles/PGS000317.txt.gz
PGS000332 PRS_BC PGP000100 Mars N et al. Nat Med (2020) Breast cancer breast carcinoma 6,390,808 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000332/ScoringFiles/PGS000332.txt.gz
PGS000333 PRS_PC PGP000100 Mars N et al. Nat Med (2020) Prostate cancer prostate carcinoma 6,606,785 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000333/ScoringFiles/PGS000333.txt.gz
PGS000335 BC_PRSCS PGP000102 Mars N et al. Nat Commun (2020) Breast cancer breast carcinoma 1,079,089 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000335/ScoringFiles/PGS000335.txt.gz
PGS000339 PRS22_CM PGP000106 Law MH et al. Hum Mol Genet (2020) Cutaneous melanoma cutaneous melanoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000339/ScoringFiles/PGS000339.txt.gz
PGS000344 PRS287_BC PGP000112 Ho WK et al. Nat Commun (2020) Breast cancer breast carcinoma 287 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000344/ScoringFiles/PGS000344.txt.gz
PGS000345 PRS229_BC PGP000112 Ho WK et al. Nat Commun (2020) Breast cancer breast carcinoma 229 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000345/ScoringFiles/PGS000345.txt.gz
PGS000346 PRS287_ERneg PGP000112 Ho WK et al. Nat Commun (2020) Estrogen receptor negative breast cancer estrogen-receptor negative breast cancer 287 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000346/ScoringFiles/PGS000346.txt.gz
PGS000347 PRS287_ERpos PGP000112 Ho WK et al. Nat Commun (2020) Estrogen receptor positive breast cancer estrogen-receptor positive breast cancer 287 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000347/ScoringFiles/PGS000347.txt.gz
PGS000348 PRS_PrCa PGP000113 Black MH et al. Prostate (2020) Prostate cancer prostate carcinoma 72 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000348/ScoringFiles/PGS000348.txt.gz - Check Terms/Licenses
PGS000351 PRS_EOC PGP000117 Barnes DR et al. Genet Med (2020) Invasive epithelial ovarian cancer ovarian carcinoma 30 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000351/ScoringFiles/PGS000351.txt.gz
PGS000352 PRS_HGS PGP000117 Barnes DR et al. Genet Med (2020) High grade serous ovarian cancer high grade ovarian serous adenocarcinoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000352/ScoringFiles/PGS000352.txt.gz
PGS000353 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000353/ScoringFiles/PGS000353.txt.gz
PGS000354 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 1,118,667 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000354/ScoringFiles/PGS000354.txt.gz
PGS000355 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000355/ScoringFiles/PGS000355.txt.gz
PGS000356 PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Any Cancer cancer 179 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000356/ScoringFiles/PGS000356.txt.gz
PGS000357 PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of mouth oral cavity cancer 45 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000357/ScoringFiles/PGS000357.txt.gz
PGS000358 PRSWEB_PHECODE145_UKBB-SAIGE-HRC-X145_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of mouth oral cavity cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000358/ScoringFiles/PGS000358.txt.gz
PGS000360 PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of larynx larynx cancer 25,920 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000360/ScoringFiles/PGS000360.txt.gz
PGS000361 PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of larynx larynx cancer 87,893 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000361/ScoringFiles/PGS000361.txt.gz
PGS000362 PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of larynx larynx cancer 53 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000362/ScoringFiles/PGS000362.txt.gz
PGS000363 PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 1,081,646 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000363/ScoringFiles/PGS000363.txt.gz
PGS000364 PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 2,001 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000364/ScoringFiles/PGS000364.txt.gz
PGS000365 PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 1,070,434 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000365/ScoringFiles/PGS000365.txt.gz
PGS000366 PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of esophagus esophageal cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000366/ScoringFiles/PGS000366.txt.gz
PGS000367 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 74 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000367/ScoringFiles/PGS000367.txt.gz
PGS000368 PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 74 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000368/ScoringFiles/PGS000368.txt.gz
PGS000369 PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 81 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000369/ScoringFiles/PGS000369.txt.gz
PGS000370 PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 87 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000370/ScoringFiles/PGS000370.txt.gz
PGS000371 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000371/ScoringFiles/PGS000371.txt.gz
PGS000372 PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000372/ScoringFiles/PGS000372.txt.gz
PGS000373 PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000373/ScoringFiles/PGS000373.txt.gz
PGS000374 PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 41 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000374/ScoringFiles/PGS000374.txt.gz
PGS000375 PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colorectal cancer colorectal cancer 370 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000375/ScoringFiles/PGS000375.txt.gz
PGS000376 PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000376/ScoringFiles/PGS000376.txt.gz
PGS000377 PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 5,740,814 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000377/ScoringFiles/PGS000377.txt.gz
PGS000378 PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 1,111,399 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000378/ScoringFiles/PGS000378.txt.gz
PGS000379 PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 5,715,093 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000379/ScoringFiles/PGS000379.txt.gz
PGS000380 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000380/ScoringFiles/PGS000380.txt.gz
PGS000381 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000381/ScoringFiles/PGS000381.txt.gz
PGS000382 PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Colon cancer colon carcinoma 150 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000382/ScoringFiles/PGS000382.txt.gz
PGS000383 PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of rectum, rectosigmoid junction, and anus rectum cancer
rectosigmoid junction neoplasm
1,078,799 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000383/ScoringFiles/PGS000383.txt.gz
PGS000384 PRSWEB_PHECODE153.3_C3-RECTUM_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of rectum, rectosigmoid junction, and anus rectum cancer
rectosigmoid junction neoplasm
1,104,018 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000384/ScoringFiles/PGS000384.txt.gz
PGS000385 PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Pancreatic cancer pancreatic carcinoma 17 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000385/ScoringFiles/PGS000385.txt.gz
PGS000386 PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Pancreatic cancer pancreatic carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000386/ScoringFiles/PGS000386.txt.gz
PGS000387 PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer within the respiratory system respiratory system cancer 879,334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000387/ScoringFiles/PGS000387.txt.gz
PGS000388 PRSWEB_PHECODE165.1_C3-BRONCHUS-LUNG_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,109,069 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000388/ScoringFiles/PGS000388.txt.gz
PGS000389 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000389/ScoringFiles/PGS000389.txt.gz
PGS000390 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000390/ScoringFiles/PGS000390.txt.gz
PGS000391 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000391/ScoringFiles/PGS000391.txt.gz
PGS000392 PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000392/ScoringFiles/PGS000392.txt.gz
PGS000393 PRSWEB_PHECODE165.1_LUNG-CANCER_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,110,438 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000393/ScoringFiles/PGS000393.txt.gz
PGS000394 PRSWEB_PHECODE165.1_LUNG-CANCER-MESOT_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,110,438 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000394/ScoringFiles/PGS000394.txt.gz
PGS000395 PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000395/ScoringFiles/PGS000395.txt.gz
PGS000396 PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
75 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000396/ScoringFiles/PGS000396.txt.gz
PGS000397 PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bronchus; lung bronchus cancer
lung cancer
tracheal cancer
46,920 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000397/ScoringFiles/PGS000397.txt.gz
PGS000398 PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 1,103,220 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000398/ScoringFiles/PGS000398.txt.gz
PGS000399 PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000399/ScoringFiles/PGS000399.txt.gz
PGS000400 PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 95 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000400/ScoringFiles/PGS000400.txt.gz
PGS000401 PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000401/ScoringFiles/PGS000401.txt.gz
PGS000402 PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 389 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000402/ScoringFiles/PGS000402.txt.gz
PGS000403 PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 16,316 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000403/ScoringFiles/PGS000403.txt.gz
PGS000404 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 80 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000404/ScoringFiles/PGS000404.txt.gz
PGS000405 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000405/ScoringFiles/PGS000405.txt.gz
PGS000406 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 292 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000406/ScoringFiles/PGS000406.txt.gz
PGS000407 PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Skin cancer skin carcinoma 3,166 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000407/ScoringFiles/PGS000407.txt.gz
PGS000408 PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000408/ScoringFiles/PGS000408.txt.gz
PGS000409 PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000409/ScoringFiles/PGS000409.txt.gz
PGS000410 PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 7 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000410/ScoringFiles/PGS000410.txt.gz
PGS000411 PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 185 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000411/ScoringFiles/PGS000411.txt.gz
PGS000412 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 16 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000412/ScoringFiles/PGS000412.txt.gz
PGS000413 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000413/ScoringFiles/PGS000413.txt.gz
PGS000414 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000414/ScoringFiles/PGS000414.txt.gz
PGS000415 PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 505 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000415/ScoringFiles/PGS000415.txt.gz
PGS000416 PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000416/ScoringFiles/PGS000416.txt.gz
PGS000417 PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,109,519 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000417/ScoringFiles/PGS000417.txt.gz
PGS000418 PRSWEB_PHECODE172.1_C43_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000418/ScoringFiles/PGS000418.txt.gz
PGS000419 PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 436 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000419/ScoringFiles/PGS000419.txt.gz
PGS000420 PRSWEB_PHECODE172.1_D03_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 147 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000420/ScoringFiles/PGS000420.txt.gz
PGS000421 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000421/ScoringFiles/PGS000421.txt.gz
PGS000422 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000422/ScoringFiles/PGS000422.txt.gz
PGS000423 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 29 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000423/ScoringFiles/PGS000423.txt.gz
PGS000424 PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000424/ScoringFiles/PGS000424.txt.gz
PGS000425 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000425/ScoringFiles/PGS000425.txt.gz
PGS000426 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000426/ScoringFiles/PGS000426.txt.gz
PGS000427 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000427/ScoringFiles/PGS000427.txt.gz
PGS000428 PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000428/ScoringFiles/PGS000428.txt.gz
PGS000429 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000429/ScoringFiles/PGS000429.txt.gz
PGS000430 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000430/ScoringFiles/PGS000430.txt.gz
PGS000431 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000431/ScoringFiles/PGS000431.txt.gz
PGS000432 PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Melanomas of skin (diagnosis or history) melanoma 296 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000432/ScoringFiles/PGS000432.txt.gz
PGS000433 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 108 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000433/ScoringFiles/PGS000433.txt.gz
PGS000434 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000434/ScoringFiles/PGS000434.txt.gz
PGS000435 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 446 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000435/ScoringFiles/PGS000435.txt.gz
PGS000436 PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 16,626 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000436/ScoringFiles/PGS000436.txt.gz
PGS000437 PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 63 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000437/ScoringFiles/PGS000437.txt.gz
PGS000438 PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000438/ScoringFiles/PGS000438.txt.gz
PGS000439 PRSWEB_PHECODE172.2_C44_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 467 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000439/ScoringFiles/PGS000439.txt.gz
PGS000440 PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 2,111 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000440/ScoringFiles/PGS000440.txt.gz
PGS000441 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 77 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000441/ScoringFiles/PGS000441.txt.gz
PGS000442 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000442/ScoringFiles/PGS000442.txt.gz
PGS000443 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 177 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000443/ScoringFiles/PGS000443.txt.gz
PGS000444 PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Other non-epithelial cancer of skin skin cancer 7,231 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000444/ScoringFiles/PGS000444.txt.gz
PGS000445 PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000445/ScoringFiles/PGS000445.txt.gz
PGS000446 PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 1,111,490 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000446/ScoringFiles/PGS000446.txt.gz
PGS000447 PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 72 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000447/ScoringFiles/PGS000447.txt.gz
PGS000448 PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 183 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000448/ScoringFiles/PGS000448.txt.gz
PGS000449 PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 1,073,162 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000449/ScoringFiles/PGS000449.txt.gz
PGS000450 PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000450/ScoringFiles/PGS000450.txt.gz
PGS000451 PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 2,231 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000451/ScoringFiles/PGS000451.txt.gz
PGS000452 PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 28 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000452/ScoringFiles/PGS000452.txt.gz
PGS000453 PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 28 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000453/ScoringFiles/PGS000453.txt.gz
PGS000454 PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000454/ScoringFiles/PGS000454.txt.gz
PGS000455 PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 28 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000455/ScoringFiles/PGS000455.txt.gz
PGS000456 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 30 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000456/ScoringFiles/PGS000456.txt.gz
PGS000457 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 30 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000457/ScoringFiles/PGS000457.txt.gz
PGS000458 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 23 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000458/ScoringFiles/PGS000458.txt.gz
PGS000459 PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Basal cell carcinoma basal cell carcinoma 24 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000459/ScoringFiles/PGS000459.txt.gz
PGS000460 PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 4,279,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000460/ScoringFiles/PGS000460.txt.gz
PGS000461 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000461/ScoringFiles/PGS000461.txt.gz
PGS000462 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000462/ScoringFiles/PGS000462.txt.gz
PGS000463 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 7 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000463/ScoringFiles/PGS000463.txt.gz
PGS000464 PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000464/ScoringFiles/PGS000464.txt.gz
PGS000465 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000465/ScoringFiles/PGS000465.txt.gz
PGS000466 PRSWEB_PHECODE172.22_cSCC-Chahal_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000466/ScoringFiles/PGS000466.txt.gz
PGS000467 PRSWEB_PHECODE172.22_cSCC-Chahal_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000467/ScoringFiles/PGS000467.txt.gz
PGS000468 PRSWEB_PHECODE172.22_cSCC-Chahal_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Squamous cell carcinoma squamous cell carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000468/ScoringFiles/PGS000468.txt.gz
PGS000469 PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Carcinoma in situ of skin skin carcinoma in situ 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000469/ScoringFiles/PGS000469.txt.gz
PGS000470 PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Carcinoma in situ of skin skin carcinoma in situ 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000470/ScoringFiles/PGS000470.txt.gz
PGS000471 PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Carcinoma in situ of skin skin carcinoma in situ 7 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000471/ScoringFiles/PGS000471.txt.gz
PGS000472 PRSWEB_PHECODE174.1_20001-1002_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000472/ScoringFiles/PGS000472.txt.gz
PGS000473 PRSWEB_PHECODE174.1_20001-1002_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,111,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000473/ScoringFiles/PGS000473.txt.gz
PGS000474 PRSWEB_PHECODE174.1_20001-1002_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 68 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000474/ScoringFiles/PGS000474.txt.gz
PGS000475 PRSWEB_PHECODE174.1_20001-1002_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 30,041 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000475/ScoringFiles/PGS000475.txt.gz
PGS000476 PRSWEB_PHECODE174.1_C3-BREAST-3_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 32 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000476/ScoringFiles/PGS000476.txt.gz
PGS000477 PRSWEB_PHECODE174.1_C3-BREAST-3_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,111,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000477/ScoringFiles/PGS000477.txt.gz
PGS000478 PRSWEB_PHECODE174.1_C3-BREAST-3_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 120 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000478/ScoringFiles/PGS000478.txt.gz
PGS000479 PRSWEB_PHECODE174.1_C3-BREAST-3_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 2,267 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000479/ScoringFiles/PGS000479.txt.gz
PGS000480 PRSWEB_PHECODE174.1_C50_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000480/ScoringFiles/PGS000480.txt.gz
PGS000481 PRSWEB_PHECODE174.1_C50_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,111,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000481/ScoringFiles/PGS000481.txt.gz
PGS000482 PRSWEB_PHECODE174.1_C50_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 42 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000482/ScoringFiles/PGS000482.txt.gz
PGS000483 PRSWEB_PHECODE174.1_C50_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 4,047 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000483/ScoringFiles/PGS000483.txt.gz
PGS000484 PRSWEB_PHECODE174.1_D05_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 25 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000484/ScoringFiles/PGS000484.txt.gz
PGS000485 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 62 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000485/ScoringFiles/PGS000485.txt.gz
PGS000486 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 86 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000486/ScoringFiles/PGS000486.txt.gz
PGS000487 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 62 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000487/ScoringFiles/PGS000487.txt.gz
PGS000488 PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 79 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000488/ScoringFiles/PGS000488.txt.gz
PGS000489 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000489/ScoringFiles/PGS000489.txt.gz
PGS000490 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000490/ScoringFiles/PGS000490.txt.gz
PGS000491 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000491/ScoringFiles/PGS000491.txt.gz
PGS000492 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,120,410 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000492/ScoringFiles/PGS000492.txt.gz
PGS000493 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 217 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000493/ScoringFiles/PGS000493.txt.gz
PGS000494 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000494/ScoringFiles/PGS000494.txt.gz
PGS000495 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 18,866 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000495/ScoringFiles/PGS000495.txt.gz
PGS000496 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 41,744 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000496/ScoringFiles/PGS000496.txt.gz
PGS000497 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 257 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000497/ScoringFiles/PGS000497.txt.gz
PGS000498 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 257 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000498/ScoringFiles/PGS000498.txt.gz
PGS000499 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000499/ScoringFiles/PGS000499.txt.gz
PGS000500 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,120,410 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000500/ScoringFiles/PGS000500.txt.gz
PGS000501 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,142 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000501/ScoringFiles/PGS000501.txt.gz
PGS000502 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 747 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000502/ScoringFiles/PGS000502.txt.gz
PGS000503 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 61,635 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000503/ScoringFiles/PGS000503.txt.gz
PGS000504 PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 148,560 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000504/ScoringFiles/PGS000504.txt.gz
PGS000505 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000505/ScoringFiles/PGS000505.txt.gz
PGS000506 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000506/ScoringFiles/PGS000506.txt.gz
PGS000507 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,140 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000507/ScoringFiles/PGS000507.txt.gz
PGS000508 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,120,410 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000508/ScoringFiles/PGS000508.txt.gz
PGS000509 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 3,038 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000509/ScoringFiles/PGS000509.txt.gz
PGS000510 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,682 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000510/ScoringFiles/PGS000510.txt.gz
PGS000511 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 118,388 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000511/ScoringFiles/PGS000511.txt.gz
PGS000512 PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 286,144 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000512/ScoringFiles/PGS000512.txt.gz
PGS000513 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 41 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000513/ScoringFiles/PGS000513.txt.gz
PGS000514 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,119,237 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000514/ScoringFiles/PGS000514.txt.gz
PGS000515 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 84 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000515/ScoringFiles/PGS000515.txt.gz
PGS000516 PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 6,977 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000516/ScoringFiles/PGS000516.txt.gz
PGS000517 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000517/ScoringFiles/PGS000517.txt.gz
PGS000518 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000518/ScoringFiles/PGS000518.txt.gz
PGS000519 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,115,376 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000519/ScoringFiles/PGS000519.txt.gz
PGS000520 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,116,435 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000520/ScoringFiles/PGS000520.txt.gz
PGS000521 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000521/ScoringFiles/PGS000521.txt.gz
PGS000522 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 14 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000522/ScoringFiles/PGS000522.txt.gz
PGS000523 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 270 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000523/ScoringFiles/PGS000523.txt.gz
PGS000524 PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 2,708 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000524/ScoringFiles/PGS000524.txt.gz
PGS000525 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 86 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000525/ScoringFiles/PGS000525.txt.gz
PGS000526 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 86 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000526/ScoringFiles/PGS000526.txt.gz
PGS000527 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,115,436 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000527/ScoringFiles/PGS000527.txt.gz
PGS000528 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,116,495 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000528/ScoringFiles/PGS000528.txt.gz
PGS000529 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 310 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000529/ScoringFiles/PGS000529.txt.gz
PGS000530 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 174 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000530/ScoringFiles/PGS000530.txt.gz
PGS000531 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 98,026 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000531/ScoringFiles/PGS000531.txt.gz
PGS000532 PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 12,277 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000532/ScoringFiles/PGS000532.txt.gz
PGS000533 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 110 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000533/ScoringFiles/PGS000533.txt.gz
PGS000534 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 110 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000534/ScoringFiles/PGS000534.txt.gz
PGS000535 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,115,484 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000535/ScoringFiles/PGS000535.txt.gz
PGS000536 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 1,116,546 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000536/ScoringFiles/PGS000536.txt.gz
PGS000537 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 363 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000537/ScoringFiles/PGS000537.txt.gz
PGS000538 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 85 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000538/ScoringFiles/PGS000538.txt.gz
PGS000539 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 18,356 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000539/ScoringFiles/PGS000539.txt.gz
PGS000540 PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Breast cancer (female) breast carcinoma 7,118 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000540/ScoringFiles/PGS000540.txt.gz
PGS000541 PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of uterus uterine cancer 18 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000541/ScoringFiles/PGS000541.txt.gz
PGS000542 PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of uterus uterine cancer 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000542/ScoringFiles/PGS000542.txt.gz
PGS000543 PRSWEB_PHECODE184_C3-FEMALE-GENITAL_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of other female genital organs female reproductive organ cancer 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000543/ScoringFiles/PGS000543.txt.gz
PGS000565 PRSWEB_PHECODE185_20001-1044_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000565/ScoringFiles/PGS000565.txt.gz
PGS000566 PRSWEB_PHECODE185_20001-1044_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,111,494 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000566/ScoringFiles/PGS000566.txt.gz
PGS000567 PRSWEB_PHECODE185_20001-1044_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 78 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000567/ScoringFiles/PGS000567.txt.gz
PGS000568 PRSWEB_PHECODE185_20001-1044_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,401 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000568/ScoringFiles/PGS000568.txt.gz
PGS000569 PRSWEB_PHECODE185_C3-PROSTATE_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 49 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000569/ScoringFiles/PGS000569.txt.gz
PGS000570 PRSWEB_PHECODE185_C3-PROSTATE_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,111,493 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000570/ScoringFiles/PGS000570.txt.gz
PGS000571 PRSWEB_PHECODE185_C3-PROSTATE_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 100 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000571/ScoringFiles/PGS000571.txt.gz
PGS000572 PRSWEB_PHECODE185_C3-PROSTATE_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,809 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000572/ScoringFiles/PGS000572.txt.gz
PGS000573 PRSWEB_PHECODE185_C61_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 31 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000573/ScoringFiles/PGS000573.txt.gz
PGS000574 PRSWEB_PHECODE185_C61_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,111,493 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000574/ScoringFiles/PGS000574.txt.gz
PGS000575 PRSWEB_PHECODE185_C61_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 47 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000575/ScoringFiles/PGS000575.txt.gz
PGS000576 PRSWEB_PHECODE185_C61_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 905 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000576/ScoringFiles/PGS000576.txt.gz
PGS000577 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 117 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000577/ScoringFiles/PGS000577.txt.gz
PGS000578 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 117 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000578/ScoringFiles/PGS000578.txt.gz
PGS000579 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 122 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000579/ScoringFiles/PGS000579.txt.gz
PGS000580 PRSWEB_PHECODE185_GWAS-Catalog-r2019-05-03-X185_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 118 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000580/ScoringFiles/PGS000580.txt.gz
PGS000581 PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 377 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000581/ScoringFiles/PGS000581.txt.gz
PGS000582 PRSWEB_PHECODE185_Pca-PRACTICAL_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 377 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000582/ScoringFiles/PGS000582.txt.gz
PGS000583 PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,119,311 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000583/ScoringFiles/PGS000583.txt.gz
PGS000584 PRSWEB_PHECODE185_Pca-PRACTICAL_PRS-CS_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,120,596 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000584/ScoringFiles/PGS000584.txt.gz
PGS000585 PRSWEB_PHECODE185_Pca-PRACTICAL_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,301 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000585/ScoringFiles/PGS000585.txt.gz
PGS000586 PRSWEB_PHECODE185_Pca-PRACTICAL_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,023 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000586/ScoringFiles/PGS000586.txt.gz
PGS000587 PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 26,418 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000587/ScoringFiles/PGS000587.txt.gz
PGS000588 PRSWEB_PHECODE185_Pca-PRACTICAL_LASSOSUM_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 178,259 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000588/ScoringFiles/PGS000588.txt.gz
PGS000589 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 42 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000589/ScoringFiles/PGS000589.txt.gz
PGS000590 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,119,236 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000590/ScoringFiles/PGS000590.txt.gz
PGS000591 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 80 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000591/ScoringFiles/PGS000591.txt.gz
PGS000592 PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of prostate prostate carcinoma 1,334 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000592/ScoringFiles/PGS000592.txt.gz
PGS000593 PRSWEB_PHECODE187_C3-MALE-GENITAL_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of other male genital organs male reproductive organ cancer 45 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000593/ScoringFiles/PGS000593.txt.gz
PGS000594 PRSWEB_PHECODE187_C3-MALE-GENITAL_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of other male genital organs male reproductive organ cancer 97 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000594/ScoringFiles/PGS000594.txt.gz
PGS000595 PRSWEB_PHECODE187.2_20001-1045_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 9 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000595/ScoringFiles/PGS000595.txt.gz
PGS000596 PRSWEB_PHECODE187.2_20001-1045_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000596/ScoringFiles/PGS000596.txt.gz
PGS000597 PRSWEB_PHECODE187.2_20001-1045_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 771 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000597/ScoringFiles/PGS000597.txt.gz
PGS000598 PRSWEB_PHECODE187.2_C3-TESTIS_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000598/ScoringFiles/PGS000598.txt.gz
PGS000599 PRSWEB_PHECODE187.2_C3-TESTIS_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 31 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000599/ScoringFiles/PGS000599.txt.gz
PGS000600 PRSWEB_PHECODE187.2_C3-TESTIS_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 250 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000600/ScoringFiles/PGS000600.txt.gz
PGS000601 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 40 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000601/ScoringFiles/PGS000601.txt.gz
PGS000602 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 40 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000602/ScoringFiles/PGS000602.txt.gz
PGS000603 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000603/ScoringFiles/PGS000603.txt.gz
PGS000604 PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of testis testicular carcinoma 44 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000604/ScoringFiles/PGS000604.txt.gz
PGS000605 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of kidney, except pelvis kidney cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000605/ScoringFiles/PGS000605.txt.gz
PGS000606 PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Malignant neoplasm of kidney, except pelvis kidney cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000606/ScoringFiles/PGS000606.txt.gz
PGS000607 PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,095,241 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000607/ScoringFiles/PGS000607.txt.gz
PGS000608 PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,097,063 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000608/ScoringFiles/PGS000608.txt.gz
PGS000609 PRSWEB_PHECODE189.2_C67_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,130 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000609/ScoringFiles/PGS000609.txt.gz
PGS000610 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000610/ScoringFiles/PGS000610.txt.gz
PGS000611 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000611/ScoringFiles/PGS000611.txt.gz
PGS000612 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 13 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000612/ScoringFiles/PGS000612.txt.gz
PGS000613 PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 15 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000613/ScoringFiles/PGS000613.txt.gz
PGS000614 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000614/ScoringFiles/PGS000614.txt.gz
PGS000615 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 106 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000615/ScoringFiles/PGS000615.txt.gz
PGS000616 PRSWEB_PHECODE189.2_UKBB-SAIGE-HRC-X189.2_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of bladder bladder carcinoma 24,359 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000616/ScoringFiles/PGS000616.txt.gz
PGS000617 PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of eye ocular cancer 834,009 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000617/ScoringFiles/PGS000617.txt.gz
PGS000618 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain and nervous system central nervous system cancer 23 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000618/ScoringFiles/PGS000618.txt.gz
PGS000619 PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain and nervous system central nervous system cancer 19 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000619/ScoringFiles/PGS000619.txt.gz
PGS000620 PRSWEB_PHECODE191.11_C71_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 522 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000620/ScoringFiles/PGS000620.txt.gz
PGS000621 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000621/ScoringFiles/PGS000621.txt.gz
PGS000622 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000622/ScoringFiles/PGS000622.txt.gz
PGS000623 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 11 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000623/ScoringFiles/PGS000623.txt.gz
PGS000624 PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000624/ScoringFiles/PGS000624.txt.gz
PGS000625 PRSWEB_PHECODE191.11_UKBB-SAIGE-HRC-X191.11_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Cancer of brain brain cancer 11 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000625/ScoringFiles/PGS000625.txt.gz
PGS000626 PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000626/ScoringFiles/PGS000626.txt.gz
PGS000627 PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 11 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000627/ScoringFiles/PGS000627.txt.gz
PGS000628 PRSWEB_PHECODE193_C3-THYROID-GLAND_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 656 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000628/ScoringFiles/PGS000628.txt.gz
PGS000629 PRSWEB_PHECODE193_C73_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000629/ScoringFiles/PGS000629.txt.gz
PGS000630 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000630/ScoringFiles/PGS000630.txt.gz
PGS000631 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000631/ScoringFiles/PGS000631.txt.gz
PGS000632 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 8 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000632/ScoringFiles/PGS000632.txt.gz
PGS000633 PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000633/ScoringFiles/PGS000633.txt.gz
PGS000634 PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 1,119,238 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000634/ScoringFiles/PGS000634.txt.gz
PGS000635 PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 5 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000635/ScoringFiles/PGS000635.txt.gz
PGS000636 PRSWEB_PHECODE193_UKBB-SAIGE-HRC-X193_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Thyroid cancer thyroid carcinoma 954 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000636/ScoringFiles/PGS000636.txt.gz
PGS000637 PRSWEB_PHECODE201_20001-1052_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 1,047,511 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000637/ScoringFiles/PGS000637.txt.gz
PGS000638 PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 16 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000638/ScoringFiles/PGS000638.txt.gz
PGS000639 PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 20 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000639/ScoringFiles/PGS000639.txt.gz
PGS000640 PRSWEB_PHECODE201_UKBB-SAIGE-HRC-X201_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Hodgkin's disease Hodgkins lymphoma 1,119,335 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000640/ScoringFiles/PGS000640.txt.gz
PGS000641 PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Non-Hodgkins lymphoma non-Hodgkins lymphoma 12 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000641/ScoringFiles/PGS000641.txt.gz
PGS000642 PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Non-Hodgkins lymphoma non-Hodgkins lymphoma 10 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000642/ScoringFiles/PGS000642.txt.gz
PGS000643 PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_PRS-CS_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Nodular lymphoma follicular lymphoma 1,048,780 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000643/ScoringFiles/PGS000643.txt.gz
PGS000644 PRSWEB_PHECODE202.21_C-FOLLICULAR-LYMPHOMA_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Nodular lymphoma follicular lymphoma 2,209,179 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000644/ScoringFiles/PGS000644.txt.gz
PGS000645 PRSWEB_PHECODE204.1_C-LYMPHOID-LEUKAEMIA_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia lymphoid leukemia 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000645/ScoringFiles/PGS000645.txt.gz
PGS000646 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 32 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000646/ScoringFiles/PGS000646.txt.gz
PGS000647 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 32 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000647/ScoringFiles/PGS000647.txt.gz
PGS000648 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 44 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000648/ScoringFiles/PGS000648.txt.gz
PGS000649 PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000649/ScoringFiles/PGS000649.txt.gz
PGS000650 PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 6 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000650/ScoringFiles/PGS000650.txt.gz
PGS000651 PRSWEB_PHECODE204.12_UKBB-SAIGE-HRC-X204.12_LASSOSUM_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Lymphoid leukemia, chronic chronic lymphocytic leukemia 76 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000651/ScoringFiles/PGS000651.txt.gz
PGS000652 PRSWEB_PHECODE204.4_C90_PT_MGI_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Multiple myeloma multiple myeloma 27 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000652/ScoringFiles/PGS000652.txt.gz
PGS000653 PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_P_5e-08_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Multiple myeloma multiple myeloma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000653/ScoringFiles/PGS000653.txt.gz
PGS000654 PRSWEB_PHECODE204.4_GWAS-Catalog-r2019-05-03-X204.4_PT_UKB_20200608 PGP000118 Fritsche LG et al. Am J Hum Genet (2020) Multiple myeloma multiple myeloma 21 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000654/ScoringFiles/PGS000654.txt.gz
PGS000662 GRS.PCa.269 PGP000122 Conti DV, Darst BF et al. Nat Genet (2020) Prostate Cancer prostate carcinoma 269 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000662/ScoringFiles/PGS000662.txt.gz
PGS000663 wGRS22 PGP000123 Kim J et al. Cancer Epidemiol Biomarkers Prev (2020) Pancreatic cancer pancreatic carcinoma 22 http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000663/ScoringFiles/PGS000663.txt.gz

PGS Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID
(PPM ID)
Evaluated Score PGS Sample Set ID
(PSS ID)
Performance Source Trait PGS Effect Sizes
(per SD change)
PGS Classification Metrics Other Metrics Covariates Included in the Model PGS Performance: Other Relevant Information
PPM000011 PGS000001 (PRS77_BC) PSS000004 PGP000002
Mavaddat N et al. (2018)
Ext.
Reported Trait: Invasive breast cancer OR: 1.46 [1.42, 1.49] AUROC: 0.603 study, genetic PCs 1-15
PPM000114 PGS000001 (PRS77_BC) PSS000070 PGP000033
Kuchenbaecker KB et al. (2017)
Ext.
Reported Trait: Breast cancer in BRCA1 mutation carriers HR: 1.13 [1.1, 1.16] Country, birth year
PPM000117 PGS000001 (PRS77_BC) PSS000071 PGP000033
Kuchenbaecker KB et al. (2017)
Ext.
Reported Trait: Breast cancer in BRCA2 mutation carriers HR: 1.22 [1.17, 1.28] Country, birth year
PPM000001 PGS000001 (PRS77_BC) PSS000001 PGP000001
Mavaddat N et al. (2015)
Reported Trait: All breast cancer OR: 1.55 [1.52, 1.58] C-index: 0.622 [0.619, 0.627]
PPM000962 PGS000001 (PRS77_BC) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.21 [1.13, 1.29] Country
PPM000961 PGS000001 (PRS77_BC) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.21 [1.14, 1.29] Country
PPM000945 PGS000001 (PRS77_BC) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.21 [1.13, 1.29] Country
PPM000944 PGS000001 (PRS77_BC) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.21 [1.14, 1.29] Country
PPM000012 PGS000002 (PRS77_ERpos) PSS000005 PGP000002
Mavaddat N et al. (2018)
Ext.
Reported Trait: ER-positive breast cancer OR: 1.52 [1.48, 1.56] AUROC: 0.615 study, genetic PCs 1-15
PPM000115 PGS000002 (PRS77_ERpos) PSS000070 PGP000033
Kuchenbaecker KB et al. (2017)
Ext.
Reported Trait: Breast cancer in BRCA1 mutation carriers HR: 1.09 [1.06, 1.12] Country, birth year
PPM000118 PGS000002 (PRS77_ERpos) PSS000071 PGP000033
Kuchenbaecker KB et al. (2017)
Ext.
Reported Trait: Breast cancer in BRCA2 mutation carriers HR: 1.22 [1.17, 1.27] Country, birth year
PPM000002 PGS000002 (PRS77_ERpos) PSS000003 PGP000001
Mavaddat N et al. (2015)
Reported Trait: ER-positive breast cancer OR: 1.63 [1.6, 1.67]
PPM000013 PGS000003 (PRS77_ERneg) PSS000006 PGP000002
Mavaddat N et al. (2018)
Ext.
Reported Trait: ER-negative breast cancer OR: 1.35 [1.27, 1.43] AUROC: 0.584 study, genetic PCs 1-15
PPM000116 PGS000003 (PRS77_ERneg) PSS000070 PGP000033
Kuchenbaecker KB et al. (2017)
Ext.
Reported Trait: Breast cancer in BRCA1 mutation carriers HR: 1.24 [1.21, 1.28] Country, birth year
PPM000119 PGS000003 (PRS77_ERneg) PSS000071 PGP000033
Kuchenbaecker KB et al. (2017)
Ext.
Reported Trait: Breast cancer in BRCA2 mutation carriers HR: 1.13 [1.08, 1.18] Country, birth year
PPM000003 PGS000003 (PRS77_ERneg) PSS000002 PGP000001
Mavaddat N et al. (2015)
Reported Trait: ER-negative breast cancer OR: 1.45 [1.4, 1.49]
PPM000005 PGS000004 (PRS313_BC) PSS000007 PGP000002
Mavaddat N et al. (2018)
Reported Trait: Incident breast cancer cases HR: 1.59 [1.54, 1.64] study, genetic PCs 1-15 Included only 306 of the 313 SNPs
PPM000004 PGS000004 (PRS313_BC) PSS000004 PGP000002
Mavaddat N et al. (2018)
Reported Trait: Invasive breast cancer OR: 1.61 [1.57, 1.65] AUROC: 0.63 study, genetic PCs 1-15
PPM000662 PGS000004 (PRS313_BC) PSS000363 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (triple negative) OR: 1.38 [1.31, 1.44] AUROC: 0.5877
PPM000659 PGS000004 (PRS313_BC) PSS000359 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (HER2-enriched-like) OR: 1.49 [1.38, 1.6] AUROC: 0.6093
PPM000656 PGS000004 (PRS313_BC) PSS000362 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (luminal B-like) OR: 1.68 [1.6, 1.77] AUROC: 0.6432
PPM000653 PGS000004 (PRS313_BC) PSS000361 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (luminal B/HER2-negative-like) OR: 1.62 [1.55, 1.71] AUROC: 0.6336
PPM000650 PGS000004 (PRS313_BC) PSS000360 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (luminal A-like) OR: 1.8 [1.75, 1.86] AUROC: 0.6573
PPM001345 PGS000004 (PRS313_BC) PSS000450 PGP000102
Mars N et al. (2020)
Ext.
Reported Trait: Breast cancer HR: 1.55 [1.52, 1.58] 10 ancestry PCs, batch, age as time scale 260/313 variants in the PRS are polymorphic in FinnGen
PPM001347 PGS000004 (PRS313_BC) PSS000450 PGP000102
Mars N et al. (2020)
Ext.
Reported Trait: Breast cancer OR: 1.61 [1.57, 1.64] Age, 10 ancestry PCs, batch 260/313 variants in the PRS are polymorphic in FinnGen
PPM000960 PGS000004 (PRS313_BC) PSS000480 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Unilateral breast cancer OR: 1.56 [1.52, 1.6] Age, country
PPM000959 PGS000004 (PRS313_BC) PSS000481 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Contralateral breast cancer OR: 1.15 [1.02, 1.29] Age, country
PPM000958 PGS000004 (PRS313_BC) PSS000483 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Unilateral breast cancer OR: 1.67 [1.59, 1.76] Age, country, PCs (1-10)
PPM000957 PGS000004 (PRS313_BC) PSS000482 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Contralateral breast cancer OR: 1.39 [1.13, 1.7] Age, country, PCs (1-10)
PPM000956 PGS000004 (PRS313_BC) PSS000483 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Unilateral breast cancer OR: 1.82 [1.8, 1.84] Age, country
PPM000955 PGS000004 (PRS313_BC) PSS000482 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Contralateral breast cancer OR: 1.3 [1.26, 1.35] Age, country
PPM000954 PGS000004 (PRS313_BC) PSS000485 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Estrogen-receptor positive metachronous invasive contralateral breast cancer HR: 1.38 [1.23, 1.55] Country
PPM000953 PGS000004 (PRS313_BC) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.24 [1.16, 1.32] Country
PPM000951 PGS000004 (PRS313_BC) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.25 [1.18, 1.33] C-index: 0.563 [0.547, 0.586] Country
PPM000943 PGS000004 (PRS313_BC) PSS000480 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Unilateral breast cancer OR: 1.56 [1.52, 1.6] Age, country
PPM000942 PGS000004 (PRS313_BC) PSS000481 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Contralateral breast cancer OR: 1.15 [1.02, 1.29] Age, country
PPM000941 PGS000004 (PRS313_BC) PSS000483 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Unilateral breast cancer OR: 1.67 [1.59, 1.76] Age, country, PCs (1-10)
PPM000940 PGS000004 (PRS313_BC) PSS000482 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Contralateral breast cancer OR: 1.39 [1.13, 1.7] Age, country, PCs (1-10)
PPM000939 PGS000004 (PRS313_BC) PSS000483 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Unilateral breast cancer OR: 1.82 [1.8, 1.84] Age, country
PPM000938 PGS000004 (PRS313_BC) PSS000482 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Contralateral breast cancer OR: 1.3 [1.26, 1.35] Age, country
PPM000937 PGS000004 (PRS313_BC) PSS000485 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Estrogen-receptor positive metachronous invasive contralateral breast cancer HR: 1.38 [1.23, 1.55] Country
PPM000936 PGS000004 (PRS313_BC) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.24 [1.16, 1.32] Country
PPM000935 PGS000004 (PRS313_BC) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer C-index: 0.623 [0.591, 0.629] Country, age at first diagnosis, year of first diagnosis, family history for breast cancer in a first degree relative, clinical characteristics of the first breast cancer (nodal status, tumor size, differentiation grade, morphology, estrogen receptor status, human epidermal growth factor receptor 2 status, chemotherapy, endocrine therapy, radiotherapy)
PPM000934 PGS000004 (PRS313_BC) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.25 [1.18, 1.33] C-index: 0.563 [0.547, 0.586] Country
PPM000952 PGS000004 (PRS313_BC) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer C-index: 0.623 [0.591, 0.629] Country, age at first diagnosis, year of first diagnosis, family history for breast cancer in a first degree relative, clinical characteristics of the first breast cancer (nodal status, tumor size, differentiation grade, morphology, estrogen receptor status, human epidermal growth factor receptor 2 status, chemotherapy, endocrine therapy, radiotherapy)
PPM001012 PGS000004 (PRS313_BC) PSS000521 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Breast cancer in BRCA1 carriers HR: 1.2 [1.17, 1.23] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001013 PGS000004 (PRS313_BC) PSS000525 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Breast cancer in BRCA2 carriers HR: 1.31 [1.26, 1.36] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001014 PGS000004 (PRS313_BC) PSS000522 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER negative breast cancer in BRCA1 carriers HR: 1.09 [1.05, 1.13] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001015 PGS000004 (PRS313_BC) PSS000526 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER negative breast cancer in BRCA2 carriers HR: 1.19 [1.1, 1.29] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001016 PGS000004 (PRS313_BC) PSS000523 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER positive breast cancer in BRCA1 carriers HR: 1.44 [1.35, 1.54] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001017 PGS000004 (PRS313_BC) PSS000527 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER positive breast cancer in BRCA2 carriers HR: 1.36 [1.3, 1.43] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001035 PGS000004 (PRS313_BC) PSS000531 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Incidient breast cancer in BRCA2 carriers HR: 1.36 [1.17, 1.57] family history of the appropriate cancer in first- and second-degree relatives
PPM000006 PGS000005 (PRS313_ERpos) PSS000005 PGP000002
Mavaddat N et al. (2018)
Reported Trait: ER-positive breast cancer OR: 1.68 [1.63, 1.73] AUROC: 0.641 study, genetic PCs 1-15
PPM000663 PGS000005 (PRS313_ERpos) PSS000363 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (triple negative) OR: 1.59 [1.51, 1.66] AUROC: 0.6276
PPM000660 PGS000005 (PRS313_ERpos) PSS000359 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (HER2-enriched-like) OR: 1.59 [1.48, 1.71] AUROC: 0.6291
PPM000657 PGS000005 (PRS313_ERpos) PSS000362 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (luminal B-like) OR: 1.66 [1.58, 1.75] AUROC: 0.64
PPM000654 PGS000005 (PRS313_ERpos) PSS000361 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (luminal B/HER2-negative-like) OR: 1.62 [1.54, 1.7] AUROC: 0.6323
PPM000651 PGS000005 (PRS313_ERpos) PSS000360 PGP000088
Zhang H et al. (2020)
Ext.
Reported Trait: Breast cancer intrinsic-like subtype (luminal A-like) OR: 1.82 [1.77, 1.87] AUROC: 0.6595
PPM000965 PGS000005 (PRS313_ERpos) PSS000485 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Estrogen-receptor positive metachronous invasive contralateral breast cancer HR: 1.37 [1.22, 1.54] Country
PPM000964 PGS000005 (PRS313_ERpos) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.22 [1.15, 1.3] Country
PPM000963 PGS000005 (PRS313_ERpos) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.23 [1.16, 1.31] Country
PPM000948 PGS000005 (PRS313_ERpos) PSS000485 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Estrogen-receptor positive metachronous invasive contralateral breast cancer HR: 1.37 [1.22, 1.54] Country
PPM000947 PGS000005 (PRS313_ERpos) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.22 [1.15, 1.3] Country
PPM000946 PGS000005 (PRS313_ERpos) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.23 [1.16, 1.31] Country
PPM001018 PGS000005 (PRS313_ERpos) PSS000521 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Breast cancer in BRCA1 carriers HR: 1.17 [1.14, 1.2] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001019 PGS000005 (PRS313_ERpos) PSS000525 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Breast cancer in BRCA2 carriers HR: 1.3 [1.26, 1.35] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001020 PGS000005 (PRS313_ERpos) PSS000522 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER negative breast cancer in BRCA1 carriers HR: 1.06 [1.02, 1.1] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001021 PGS000005 (PRS313_ERpos) PSS000526 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER negative breast cancer in BRCA2 carriers HR: 1.15 [1.07, 1.25] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001022 PGS000005 (PRS313_ERpos) PSS000523 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER positive breast cancer in BRCA1 carriers HR: 1.45 [1.35, 1.54] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001023 PGS000005 (PRS313_ERpos) PSS000527 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER positive breast cancer in BRCA2 carriers HR: 1.37 [1.31, 1.44] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM000007 PGS000006 (PRS313_ERneg) PSS000006 PGP000002
Mavaddat N et al. (2018)
Reported Trait: ER-negative breast cancer OR: 1.45 [1.37, 1.53] AUROC: 0.601 study, genetic PCs 1-15
PPM000950 PGS000006 (PRS313_ERneg) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.24 [1.16, 1.33] Country
PPM000949 PGS000006 (PRS313_ERneg) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.25 [1.17, 1.33] Country
PPM000967 PGS000006 (PRS313_ERneg) PSS000486 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Invasive metachronous contralateral breast cancer HR: 1.24 [1.16, 1.33] Country
PPM000966 PGS000006 (PRS313_ERneg) PSS000484 PGP000109
Kramer I et al. (2020)
Ext.
Reported Trait: Metachronous contralateral breast cancer HR: 1.25 [1.17, 1.33] Country
PPM001024 PGS000006 (PRS313_ERneg) PSS000521 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Breast cancer in BRCA1 carriers HR: 1.29 [1.25, 1.33] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001025 PGS000006 (PRS313_ERneg) PSS000525 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Breast cancer in BRCA2 carriers HR: 1.23 [1.18, 1.27] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001026 PGS000006 (PRS313_ERneg) PSS000522 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER negative breast cancer in BRCA1 carriers HR: 1.23 [1.18, 1.27] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001027 PGS000006 (PRS313_ERneg) PSS000526 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER negative breast cancer in BRCA2 carriers HR: 1.29 [1.19, 1.41] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001028 PGS000006 (PRS313_ERneg) PSS000523 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER positive breast cancer in BRCA1 carriers HR: 1.29 [1.21, 1.37] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001029 PGS000006 (PRS313_ERneg) PSS000527 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: ER positive breast cancer in BRCA2 carriers HR: 1.21 [1.15, 1.27] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001034 PGS000006 (PRS313_ERneg) PSS000529 PGP000117
Barnes DR et al. (2020)
Ext.
Reported Trait: Incident breast cancer in BRCA1 carriers HR: 1.28 [1.14, 1.44] family history of the appropriate cancer in first- and second-degree relatives
PPM000008 PGS000007 (PRS3820_BC) PSS000004 PGP000002
Mavaddat N et al. (2018)
Reported Trait: Invasive breast cancer OR: 1.66 [1.61, 1.7] AUROC: 0.636 study, genetic PCs 1-15
PPM000386 PGS000007 (PRS3820_BC) PSS000218 PGP000057
Homburger JR et al. (2019)
Ext.
Reported Trait: Breast Cancer (personal history) AUROC: 0.78 age, sex
PPM000384 PGS000007 (PRS3820_BC) PSS000218 PGP000057
Homburger JR et al. (2019)
Ext.
Reported Trait: Breast Cancer (personal history) OR: 1.56 [1.45, 1.68] age at menarche
PPM000388 PGS000007 (PRS3820_BC) PSS000218 PGP000057
Homburger JR et al. (2019)
Ext.
Reported Trait: Breast Cancer (personal history) AUROC: 0.63
PPM000009 PGS000008 (PRS3820_ERpos) PSS000005 PGP000002
Mavaddat N et al. (2018)
Reported Trait: ER-positive breast cancer OR: 1.73 [1.68, 1.78] AUROC: 0.647 study, genetic PCs 1-15
PPM000010 PGS000009 (PRS3820_ERneg) PSS000006 PGP000002
Mavaddat N et al. (2018)
Reported Trait: ER-negative breast cancer OR: 1.44 [1.36, 1.53] AUROC: 0.6 study, genetic PCs 1-15
PPM000024 PGS000015 (GPS_BC) PSS000014 PGP000006
Khera AV et al. (2018)
Reported Trait: Breast cancer AUROC: 0.69 [0.68, 0.69] Nagelkerke’s R2 (estimate of variance explained by the PGS after covariate adjustment): 0.027 age; sex; Ancestry PC 1-4; genotyping chip
PPM000056 PGS000028 (PRS) PSS000040 PGP000018
Shieh Y et al. (2016)
Reported Trait: Breast cancer AUROC: 0.65 [0.61, 0.68] BCSC risk model BCSC risk model includes mammographic breast density, age, ethnicity, first-degree relative with breast cancer, and history of breast biopsy
PPM000055 PGS000028 (PRS) PSS000040 PGP000018
Shieh Y et al. (2016)
Reported Trait: Breast cancer AUROC: 0.6 [0.57, 0.64]
PPM000060 PGS000028 (PRS) PSS000039 PGP000018
Shieh Y et al. (2016)
Reported Trait: Breast cancer AUROC: 0.63 [0.59, 0.67]
PPM000059 PGS000028 (PRS) PSS000038 PGP000018
Shieh Y et al. (2016)
Reported Trait: Breast cancer AUROC: 0.62 [0.52, 0.73]
PPM000058 PGS000029 (PRS_AS) PSS000038 PGP000018
Shieh Y et al. (2016)
Reported Trait: Breast cancer AUROC: 0.72 [0.62, 0.82] BCSC risk model BCSC risk model includes mammographic breast density, age, ethnicity, first-degree relative with breast cancer, and history of breast biopsy
PPM000057 PGS000029 (PRS_AS) PSS000038 PGP000018
Shieh Y et al. (2016)
Reported Trait: Breast cancer AUROC: 0.64 [0.53, 0.74]
PPM000061 PGS000030 (PrCa) PSS000041 PGP000019
Schumacher FR et al. (2018)
Reported Trait: Prostate cancer OR: 1.86 [1.83, 1.89] Top 7 Genetic PCs, country Samples were also part of the variant association
PPM000105 PGS000044 (PrCa66) PSS000069 PGP000032
Pashayan N et al. (2015)
Ext.
Reported Trait: aggressive prostate cancer (Gleason score ⩾7) OR (above vs. below 50th percentile of PRS): 1.56 [1.15, 2.1]
PPM000104 PGS000044 (PrCa66) PSS000068 PGP000031
Pashayan N et al. (2015)
Reported Trait: Elevated serum prostate-specific antigen (PSA) levels OR (per 1-point increase in PRS): 1.23 [1.1, 1.37] cancer stage, Gleason score
PPM000120 PGS000045 (BCPRS_Overall) PSS000074 PGP000034
Lecarpentier J et al. (2017)
Ext.
Reported Trait: Breast cancer in male carriers of BRCA1/2 mutations OR: 1.36 [1.19, 1.56] AUROC: 0.59 [0.55, 0.63] 3 PCs of ancestry, age at breast or prostate cancer for patient-cases and age at interview for controls, mutation status of BRCA1 or BRCA2 PGS predicting Male Breast Cancer are based on association statistics from a Female Breast Cancer GWAS
PPM000106 PGS000045 (BCPRS_Overall) PSS000070 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Breast cancer in BRCA1 mutation carriers HR: 1.14 [1.11, 1.17] C-index: 0.541 [0.53, 0.551] Country, birth year
PPM000107 PGS000045 (BCPRS_Overall) PSS000071 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Breast cancer in BRCA2 mutation carriers HR: 1.22 [1.17, 1.28] C-index: 0.566 [0.551, 0.581] Country, birth year
PPM000121 PGS000046 (BCPRS_ER+) PSS000074 PGP000034
Lecarpentier J et al. (2017)
Ext.
Reported Trait: Breast cancer in male carriers of BRCA1/2 mutations OR: 1.36 [1.19, 1.56] AUROC: 0.59 [0.55, 0.63] 3 PCs of ancestry, age at breast or prostate cancer for patient-cases and age at interview for controls, mutation status of BRCA1 or BRCA2 PGS predicting Male Breast Cancer are based on association statistics from a Female Breast Cancer GWAS
PPM000108 PGS000046 (BCPRS_ER+) PSS000070 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Breast cancer in BRCA1 mutation carriers HR: 1.11 [1.08, 1.15] C-index: 0.532 [0.522, 0.543] Country, birth year
PPM000109 PGS000046 (BCPRS_ER+) PSS000071 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Breast cancer in BRCA2 mutation carriers HR: 1.22 [1.16, 1.27] C-index: 0.566 [0.551, 0.581] Country, birth year
PPM000122 PGS000047 (BCPRS_ER-) PSS000074 PGP000034
Lecarpentier J et al. (2017)
Ext.
Reported Trait: Breast cancer in male carriers of BRCA1/2 mutations OR: 1.19 [1.05, 1.35] AUROC: 0.55 [0.51, 0.59] 3 PCs of ancestry, age at breast or prostate cancer for patient-cases and age at interview for controls, mutation status of BRCA1 or BRCA2 PGS predicting Male Breast Cancer are based on association statistics from a Female Breast Cancer GWAS
PPM000110 PGS000047 (BCPRS_ER-) PSS000070 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Breast cancer in BRCA1 mutation carriers HR: 1.27 [1.23, 1.31] C-index: 0.581 [0.571, 0.592] Country, birth year
PPM000111 PGS000047 (BCPRS_ER-) PSS000071 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Breast cancer in BRCA2 mutation carriers HR: 1.15 [1.1, 1.2] C-index: 0.538 [0.523, 0.553] Country, birth year
PPM000112 PGS000048 (OCPRS_Overall) PSS000072 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Ovarian cancer in BRCA1 mutation carriers HR: 1.28 [1.22, 1.34] C-index: 0.579 [0.559, 0.6] Country, birth year
PPM000113 PGS000048 (OCPRS_Overall) PSS000073 PGP000033
Kuchenbaecker KB et al. (2017)
Reported Trait: Ovarian cancer in BRCA2 mutation carriers HR: 1.49 [1.34, 1.65] C-index: 0.628 [0.592, 0.665] Country, birth year
PPM000123 PGS000049 (PRS103_PrCa) PSS000075 PGP000034
Lecarpentier J et al. (2017)
Reported Trait: Prostate cancer in male carriers of BRCA1/2 mutations OR: 1.56 [1.35, 1.81] AUROC: 0.62 [0.58, 0.66] 3 PCs of ancestry, age at breast or prostate cancer for patient-cases and age at interview for controls, mutation status of BRCA1 or BRCA2
PPM000124 PGS000049 (PRS103_PrCa) PSS000077 PGP000034
Lecarpentier J et al. (2017)
Reported Trait: Low prostate cancer aggressiveness (Gleason score < 7) OR: 1.44 [1.1, 1.87] 3 PCs of ancestry, age at breast or prostate cancer for patient-cases and age at interview for controls, mutation status of BRCA1 or BRCA2
PPM000125 PGS000049 (PRS103_PrCa) PSS000076 PGP000034
Lecarpentier J et al. (2017)
Reported Trait: High prostate cancer aggressiveness (Gleason score ≥ 7) OR: 1.67 [1.37, 2.04] 3 PCs of ancestry, age at breast or prostate cancer for patient-cases and age at interview for controls, mutation status of BRCA1 or BRCA2
PPM000126 PGS000050 (PRS44) PSS000078 PGP000035
Wen W et al. (2016)
Reported Trait: Breast cancer AUROC: 0.606 Odds Ratio (OR; per decile of PRS): 1.13 [1.12, 1.14] NR Potentially overfit: samples were used to select the variants included in the PRS (see paper's Discussion section for more information).
PPM000127 PGS000050 (PRS44) PSS000079 PGP000035
Wen W et al. (2016)
Reported Trait: Breast cancer C-index: 0.602 C-index improvement (with PRS): 0.0386 [0.0259, 0.0513] age at menarche, age at first live birth, waist-to-hip ratio, breast cancer family history, prior benign breast disease Potentially overfit: samples were used to select the variants included in the PRS (see paper's Discussion section for more information).
PPM000128 PGS000051 (PRS67) PSS000080 PGP000036
Zhang X et al. (2018)
Reported Trait: Invasive breast cancer AUROC: 0.65 [0.64, 0.66] Gail BC risk model, Mammographic density (MD), Testoterone (T), estrone sulfate (E1S), prolactin (PRL) Age-adjusted AUC
PPM000129 PGS000051 (PRS67) PSS000081 PGP000036
Zhang X et al. (2018)
Reported Trait: Invasive breast cancer AUROC: 0.678 [0.666, 0.69] Rosner–Colditz BC risk model, Mammographic density (MD), Testoterone (T), estrone sulfate (E1S), prolactin (PRL) Age-adjusted AUC
PPM000130 PGS000051 (PRS67) PSS000080 PGP000036
Zhang X et al. (2018)
Reported Trait: Invasive breast cancer Relative Risk (RR; higest vs. lowest quartile PRS): 2.5 [2.2, 2.8] Demographics and parameters of baseline blood draw (age, BMI, fasting status, time of day, season), history of benign breast disease, family history of breast cancer, age at menopause, age at menarche, physical activity, age at first birth and parity
PPM000131 PGS000052 (sPRS161) PSS000082 PGP000037
Lakeman IMM et al. (2019)
Reported Trait: breast cancer HR: 1.16 [1.03, 1.28] family history (estimated using the BOADICEA risk model)
PPM000139 PGS000055 (PRS_CRC) PSS000087 PGP000040
Schmit SL et al. (2019)
Reported Trait: Colorectal cancer Familial relative risk explained (%): 11.9 [9.2, 15.5]
PRS percentile threshold for Odds Ratio > 2: 95.7
age, sex, PCs, PC*study
PPM000140 PGS000055 (PRS_CRC) PSS000086 PGP000040
Schmit SL et al. (2019)
Reported Trait: Colorectal cancer PRS percentile threshold for Odds Ratio > 2: 99.1 age, sex, PCs, PC*study
PPM000183 PGS000067 (PCa_PHS) PSS000105 PGP000047
Seibert TM et al. (2018)
Reported Trait: aggressive prostate cancer (age at onset) z-test (p-value) < 1e-16
PPM000182 PGS000067 (PCa_PHS) PSS000105 PGP000047
Seibert TM et al. (2018)
Reported Trait: aggressive prostate cancer HR (Hazard ratio; top 2% vs. average risk): 2.9 [2.4, 3.4]
PPM000184 PGS000067 (PCa_PHS) PSS000106 PGP000047
Seibert TM et al. (2018)
Reported Trait: any prostate cancer HR (Hazard ratio; top 2% vs. average risk): 2.5 [2.2, 2.8]
PPM000185 PGS000067 (PCa_PHS) PSS000106 PGP000047
Seibert TM et al. (2018)
Reported Trait: any prostate cancer (age at onset) z-test (p-value) < 1e-16
PPM000187 PGS000067 (PCa_PHS) PSS000107 PGP000047
Seibert TM et al. (2018)
Reported Trait: very aggressive prostate cancer (age at onset) z-test (p-value) < 1e-11
PPM000393 PGS000067 (PCa_PHS) PSS000221 PGP000058
Huynh-Le M et al. (2019)
Ext. Pre
Reported Trait: Age of aggressive prostate cancer onset Hazard Ratio (HR; top 20% vs. rest): 2.4 [2.3, 2.6] Association between PHS and age-at-onset p-value < 10e-16. Only SNPs directly genotyped on the OncoArray genotyping array were considered. 46 of the score's 54 SNPs were used: 24 directly genotyped, and 22 with acceptable proxies (r2>0.94).
PPM000392 PGS000067 (PCa_PHS) PSS000222 PGP000058
Huynh-Le M et al. (2019)
Ext. Pre
Reported Trait: Age of aggressive prostate cancer onset Hazard Ratio (HR; top 20% vs. rest): 5.2 [4.8, 5.6] Association between PHS and age-at-onset p-value < 10e-16. Only SNPs directly genotyped on the OncoArray genotyping array were considered. 46 of the score's 54 SNPs were used: 24 directly genotyped, and 22 with acceptable proxies (r2>0.94).
PPM000391 PGS000067 (PCa_PHS) PSS000223 PGP000058
Huynh-Le M et al. (2019)
Ext. Pre
Reported Trait: Age of aggressive prostate cancer onset Hazard Ratio (HR; top 20% vs. rest): 5.6 [5.2, 6.0] Association between PHS and age-at-onset p-value < 10e-16. Only SNPs directly genotyped on the OncoArray genotyping array were considered. 46 of the score's 54 SNPs were used: 24 directly genotyped, and 22 with acceptable proxies (r2>0.94).
PPM000390 PGS000067 (PCa_PHS) PSS000220 PGP000058
Huynh-Le M et al. (2019)
Ext. Pre
Reported Trait: Age of aggressive prostate cancer onset Hazard Ratio (HR; top 20% vs. rest): 5.9 [5.5, 6.3] Association between PHS and age-at-onset p-value < 10e-16. Only SNPs directly genotyped on the OncoArray genotyping array were considered. 46 of the score's 54 SNPs were used: 24 directly genotyped, and 22 with acceptable proxies (r2>0.94).
PPM000394 PGS000067 (PCa_PHS) PSS000224 PGP000058
Huynh-Le M et al. (2019)
Ext. Pre
Reported Trait: Age of prostate cancer death Hazard Ratio (HR; top 20% vs. rest): 5.7 [4.6, 7.0] Association between PHS and age-at-onset p-value < 10e-16. Only SNPs directly genotyped on the OncoArray genotyping array were considered. 46 of the score's 54 SNPs were used: 24 directly genotyped, and 22 with acceptable proxies (r2>0.94).
PPM000186 PGS000067 (PCa_PHS) PSS000107 PGP000047
Seibert TM et al. (2018)
Reported Trait: very aggressive prostate cancer HR (Hazard ratio; top 2% vs. average risk): 3.0 [2.2, 4.0]
PPM000188 PGS000068 (PRS_EOC) PSS000108 PGP000048
Yang X et al. (2018)
Reported Trait: all invasive epithelial ovarian cancer OR: 1.32 [1.21, 1.45] C-index: 0.58 [0.55, 0.6]
PPM000189 PGS000069 (PRS_sEOC) PSS000108 PGP000048
Yang X et al. (2018)
Reported Trait: serous epithelial ovarian cancer OR: 1.43 [1.29, 1.58] C-index: 0.6 [0.57, 0.63]
PPM000190 PGS000070 (PRS_LC_C) PSS000109 PGP000049
Dai J et al. (2019)
Reported Trait: Incident lung cancer HR (High genetic risk: top 5% vs. bottom 5% of PRS): 2.37 [1.64, 3.44]
HR (Intermediate genetic risk: 5-95% vs. bottom 5% of PRS): 1.6 [1.17, 2.2]
age, sex, source of region, smoking status
PPM000191 PGS000071 (CC_Bladder) PSS000110 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Bladder cancer OR: 1.3 [1.25, 1.36] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000192 PGS000072 (CC_Breast) PSS000111 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Breast cancer OR: 1.26 [1.24, 1.28] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000193 PGS000073 (CC_Cervix) PSS000112 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Cervical cancer OR: 1.22 [1.19, 1.25] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000194 PGS000074 (CC_Colorectal) PSS000113 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Colorectal cancer OR: 1.37 [1.33, 1.4] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000195 PGS000075 (CC_Endo) PSS000114 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Endometrial cancer OR: 1.19 [1.14, 1.24] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000196 PGS000076 (CC_Kidney) PSS000115 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Kidney cancer OR: 1.21 [1.14, 1.27] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000197 PGS000077 (CC_LL) PSS000116 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Lymphocytic leukemia OR: 1.42 [1.33, 1.51] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000198 PGS000078 (CC_Lung) PSS000117 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Lung cancer OR: 1.12 [1.08, 1.17] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000199 PGS000079 (CC_Melanoma) PSS000118 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Melanoma OR: 1.44 [1.41, 1.48] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000200 PGS000080 (CC_NHL) PSS000119 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Non-Hodgkin's lymphoma OR: 1.25 [1.2, 1.3] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000201 PGS000081 (CC_Oral) PSS000120 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Oral cavity and pharyngeal cancers OR: 1.08 [1.02, 1.14] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000202 PGS000082 (CC_Ovary) PSS000121 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Ovarian cancer OR: 1.14 [1.08, 1.2] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000203 PGS000083 (CC_Pancreas) PSS000122 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Pancreatic cancer OR: 1.44 [1.33, 1.55] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000204 PGS000084 (CC_Prostate) PSS000123 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Prostate cancer OR: 1.44 [1.41, 1.47] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000205 PGS000085 (CC_Stomach) PSS000124 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Esophageal and stomach cancers OR: 1.07 [1.0, 1.13] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000206 PGS000086 (CC_Testis) PSS000125 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Testicular cancer OR: 2.29 [2.13, 2.47] Genotyping array, age, 10 PCs.
PPM000207 PGS000087 (CC_Thyroid) PSS000126 PGP000050
Graff RE et al. (2020)
Pre
Reported Trait: Thyroid cancer OR: 1.55 [1.44, 1.67] Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM000348 PGS000118 (MEL29) PSS000210 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Melanoma OR: 1.5 [1.44, 1.55] age, sex, genotyping array, first 4 genotype PCs
PPM000345 PGS000118 (MEL29) PSS000211 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Skin cancer OR: 1.2 [1.22, 1.36] age, sex, genotyping array, first 4 genotype PCs
PPM000342 PGS000118 (MEL29) PSS000207 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Skin cancer OR: 1.3 [1.26, 1.34] AUROC: 0.57 [0.56, 0.58] age, sex, batch, PC1-4
PPM000339 PGS000118 (MEL29) PSS000206 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Melanoma OR: 1.48 [1.41, 1.56] AUROC: 0.61 [0.59, 0.62] age, sex, batch, PC1-4
PPM000347 PGS000119 (BCC32) PSS000211 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Skin cancer OR: 1.4 [1.42, 1.48] age, sex, genotyping array, first 4 genotype PCs
PPM000344 PGS000119 (BCC32) PSS000207 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Skin cancer OR: 1.32 [1.27, 1.36] AUROC: 0.58 [0.56, 0.58] age, sex, batch, PC1-4
PPM000341 PGS000119 (BCC32) PSS000209 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Basal cell carcinoma OR: 1.65 [1.56, 1.75] AUROC: 0.64 [0.62, 0.66] age, sex, batch, PC1-4
PPM000346 PGS000120 (SCC10) PSS000211 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Skin cancer OR: 1.3 [1.3, 1.34] age, sex, genotyping array, first 4 genotype PCs
PPM000343 PGS000120 (SCC10) PSS000207 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Skin cancer OR: 1.34 [1.3, 1.38] AUROC: 0.58 [0.57, 0.6] age, sex, batch, PC1-4
PPM000340 PGS000120 (SCC10) PSS000208 PGP000055
Fritsche LG et al. (2019)
Reported Trait: Squamous cell carcinoma OR: 1.4 [1.31, 1.5] AUROC: 0.59 [0.56, 0.61] age, sex, batch, PC1-4
PPM000439 PGS000146 (CRC_GRS_27) PSS000252 PGP000069
Hsu L et al. (2015)
Reported Trait: Distal colon cancer OR: 1.08 [1.06, 1.11] Study, age, endoscopy, family history
PPM000438 PGS000146 (CRC_GRS_27) PSS000254 PGP000069
Hsu L et al. (2015)
Reported Trait: Proximal colon cancer OR: 1.07 [1.04, 1.1] Study, age, endoscopy, family history
PPM000445 PGS000146 (CRC_GRS_27) PSS000257 PGP000069
Hsu L et al. (2015)
Reported Trait: Colorectal cancer AUROC: 0.56 [0.51, 0.61] Age, endoscopy, family history
PPM000444 PGS000146 (CRC_GRS_27) PSS000258 PGP000069
Hsu L et al. (2015)
Reported Trait: Colorectal cancer AUROC: 0.59 [0.54, 0.64] Age, endoscopy, family history
PPM000443 PGS000146 (CRC_GRS_27) PSS000255 PGP000069
Hsu L et al. (2015)
Reported Trait: Rectal cancer OR: 1.12 [1.08, 1.15] Study, age, endoscopy, family history
PPM000442 PGS000146 (CRC_GRS_27) PSS000251 PGP000069
Hsu L et al. (2015)
Reported Trait: Distal colon cancer OR: 1.08 [1.05, 1.1] Study, age, endoscopy, family history
PPM000441 PGS000146 (CRC_GRS_27) PSS000253 PGP000069
Hsu L et al. (2015)
Reported Trait: Proximal colon cancer OR: 1.06 [1.03, 1.08] Study, age, endoscopy, family history
PPM000440 PGS000146 (CRC_GRS_27) PSS000256 PGP000069
Hsu L et al. (2015)
Reported Trait: Rectal cancer OR: 1.06 [1.03, 1.09] Study, age, endoscopy, family history
PPM000448 PGS000147 (CRC21) PSS000259 PGP000070
Ibáñez-Sanz G et al. (2017)
Reported Trait: Colorectal cancer AUROC: 0.63 [0.6, 0.66] Odds Ratio (OR; per allele): 1.07 [1.04, 1.1] environmental risk factors ( alcohol consumption, obesity, physical activity, red meat and vegetable consumption, nonsteroidal anti-inflammatory drug use), family history
PPM000447 PGS000147 (CRC21) PSS000259 PGP000070
Ibáñez-Sanz G et al. (2017)
Reported Trait: Rectal cancer Odds Ratio (OR; per allele): 1.1 [1.06, 1.15] environmental risk factors ( alcohol consumption, obesity, physical activity, red meat and vegetable consumption, nonsteroidal anti-inflammatory drug use), family history
PPM000446 PGS000147 (CRC21) PSS000259 PGP000070
Ibáñez-Sanz G et al. (2017)
Reported Trait: Colon cancer Odds Ratio (OR; per allele): 1.06 [1.03, 1.09] environmental risk factors ( alcohol consumption, obesity, physical activity, red meat and vegetable consumption, nonsteroidal anti-inflammatory drug use), family history
PPM000449 PGS000147 (CRC21) PSS000259 PGP000070
Ibáñez-Sanz G et al. (2017)
Reported Trait: Colorectal cancer AUROC: 0.56 [0.54, 0.58]
PPM000452 PGS000148 (CRC63) PSS000260 PGP000071
Jeon J et al. (2018)
Reported Trait: Colorectal cancer AUROC: 0.59 [0.58, 0.6] age, family history, study, endoscopy history Risk prediction using Model III (Family History & G-score)
PPM000451 PGS000148 (CRC63) PSS000261 PGP000071
Jeon J et al. (2018)
Reported Trait: Colorectal cancer AUROC: 0.63 [0.62, 0.64] age, family history, study, endoscopy history, E-score (height, body mass index, education, history of type 2 diabetes mellitus, smoking status, alcohol consumption, regular aspirin use, regular NSAIDs use, smoking pack-years, dietary factors, total-energy, physical activity) Risk prediction using Model IV (Family history & E-score & G-score)
PPM000450 PGS000148 (CRC63) PSS000261 PGP000071
Jeon J et al. (2018)
Reported Trait: Colorectal cancer AUROC: 0.59 [0.58, 0.6] age, family history, study, endoscopy history Risk prediction using Model III (Family History & G-score)
PPM000453 PGS000148 (CRC63) PSS000260 PGP000071
Jeon J et al. (2018)
Reported Trait: Colorectal cancer AUROC: 0.62 [0.61, 0.63] age, family history, study, endoscopy history, E-score (height, body mass index, education, history of type 2 diabetes mellitus, smoking status, alcohol consumption, regular aspirin use, regular NSAIDs use, regular use of post-menopausal hormones, smoking pack-years, dietary factors, total-energy, physical activity) Risk prediction using Model IV (Family history & E-score & G-score)
PPM000464 PGS000149 (CRC41) PSS000263 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals with a family history C-index: 0.68 [0.67, 0.7] Wells et al. model (age, diabetes, multi-vitamin usage, family history of colon cancer, years of education, body mass index, alcohol intake, physical activity, non-steroidal anti-inflammatory drug usage, red meat intake, smoking and oestrogen use [women only]) Fully recalibrated model
PPM000463 PGS000149 (CRC41) PSS000263 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer C-index: 0.68 [0.67, 0.7] Wells et al. model (age, diabetes, multi-vitamin usage, family history of colon cancer, years of education, body mass index, alcohol intake, physical activity, non-steroidal anti-inflammatory drug usage, red meat intake, smoking and oestrogen use [women only]) Fully recalibrated model
PPM000459 PGS000149 (CRC41) PSS000262 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals without a family history C-index: 0.66 [0.62, 0.69] Taylor et al. model (age-specific rates of CRC with estimated relative risks for different degrees of CRC family history) Fully recalibrated model
PPM000458 PGS000149 (CRC41) PSS000262 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals with a family history C-index: 0.69 [0.67, 0.7] Taylor et al. model (age-specific rates of CRC with estimated relative risks for different degrees of CRC family history) Fully recalibrated model
PPM000457 PGS000149 (CRC41) PSS000262 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer C-index: 0.68 [0.67, 0.7] Taylor et al. model (age-specific rates of CRC with estimated relative risks for different degrees of CRC family history) Fully recalibrated model
PPM000465 PGS000149 (CRC41) PSS000263 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals without a family history C-index: 0.67 [0.63, 0.71] Wells et al. model (age, diabetes, multi-vitamin usage, family history of colon cancer, years of education, body mass index, alcohol intake, physical activity, non-steroidal anti-inflammatory drug usage, red meat intake, smoking and oestrogen use [women only]) Fully recalibrated model
PPM000462 PGS000149 (CRC41) PSS000263 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals without a family history C-index: 0.57 [0.53, 0.6]
PPM000461 PGS000149 (CRC41) PSS000263 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals with a family history C-index: 0.56 [0.55, 0.58]
PPM000460 PGS000149 (CRC41) PSS000263 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer C-index: 0.57 [0.55, 0.58]
PPM000456 PGS000149 (CRC41) PSS000262 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals without a family history C-index: 0.55 [0.52, 0.59]
PPM000455 PGS000149 (CRC41) PSS000262 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer in individuals with a family history C-index: 0.57 [0.55, 0.58]
PPM000454 PGS000149 (CRC41) PSS000262 PGP000072
Smith T et al. (2018)
Reported Trait: Incident colorectal cancer C-index: 0.56 [0.55, 0.58]
PPM000469 PGS000150 (GRS48) PSS000269 PGP000073
Weigl K et al. (2018)
Reported Trait: advanced neoplasm (colorectal cancer) C-index: 0.615 Odds Ratio (OR; highest vs. lowest tertile of GRS): 2.74 [1.84, 4.09] sex, age, previous colonoscopy, physical activity
PPM000468 PGS000150 (GRS48) PSS000269 PGP000073
Weigl K et al. (2018)
Reported Trait: advanced neoplasm (colorectal cancer) C-index: 0.599 Odds Ratio (OR; highest vs. lowest tertile of GRS): 2.64 [1.77, 3.92] sex, age
PPM000467 PGS000150 (GRS48) PSS000268 PGP000073
Weigl K et al. (2018)
Reported Trait: non-advanced adenoma (colorectal) C-index: 0.596 Odds Ratio (OR; highest vs. lowest tertile of GRS): 1.05 [0.7, 1.55] sex, age, previous colonoscopy, physical activity
PPM000466 PGS000150 (GRS48) PSS000268 PGP000073
Weigl K et al. (2018)
Reported Trait: non-advanced adenoma (colorectal) C-index: 0.584 Odds Ratio (OR; highest vs. lowest tertile of GRS): 1.04 [0.7, 1.55] sex, age
PPM000471 PGS000151 (SC_GRS) PSS000271 PGP000074
Xin J et al. (2018)
Reported Trait: Colorectal cancer AUROC: 0.607 [0.581, 0.633] smoking status
PPM000470 PGS000151 (SC_GRS) PSS000271 PGP000074
Xin J et al. (2018)
Reported Trait: Colorectal cancer AUROC: 0.6 [0.579, 0.622]
PPM000472 PGS000152 (cGRS_Bladder) PSS000272 PGP000075
Shi Z et al. (2019)
Reported Trait: Bladder cancer Mean realative risk: 1.04 [1.0, 1.08]
Wilcoxon test (case vs. control) p-value: 0.00377
PPM000483 PGS000152 (cGRS_Bladder) PSS000272 PGP000075
Shi Z et al. (2019)
Reported Trait: Bladder cancer Odds Ratio (OR; high vs. average risk groups): 1.58 [1.1, 2.25]
PPM000484 PGS000153 (cGRS_Breast) PSS000273 PGP000075
Shi Z et al. (2019)
Reported Trait: Breast cancer Odds Ratio (OR; high vs. average risk groups): 1.47 [1.23, 1.76]
PPM000473 PGS000153 (cGRS_Breast) PSS000273 PGP000075
Shi Z et al. (2019)
Reported Trait: Breast cancer Mean realative risk: 1.15 [1.11, 1.2]
Wilcoxon test (case vs. control) p-value: 1.48e-14
PPM000474 PGS000154 (cGRS_Colorectal) PSS000274 PGP000075
Shi Z et al. (2019)
Reported Trait: Colorectal cancer Mean realative risk: 1.08 [1.04, 1.12]
Wilcoxon test (case vs. control) p-value: 8.29e-06
PPM000485 PGS000154 (cGRS_Colorectal) PSS000274 PGP000075
Shi Z et al. (2019)
Reported Trait: Colorectal cancer Odds Ratio (OR; high vs. average risk groups): 1.18 [0.87, 1.61]
PPM000487 PGS000156 (cGRS_Lung) PSS000276 PGP000075
Shi Z et al. (2019)
Reported Trait: Lung cancer Odds Ratio (OR; high vs. average risk groups): 0.88 [0.57, 1.36]
PPM000476 PGS000156 (cGRS_Lung) PSS000276 PGP000075
Shi Z et al. (2019)
Reported Trait: Lung cancer Mean realative risk: 1.01 [0.99, 1.02]
Wilcoxon test (case vs. control) p-value: 0.0116
PPM000488 PGS000157 (cGRS_Melanoma) PSS000277 PGP000075
Shi Z et al. (2019)
Reported Trait: Melanoma Odds Ratio (OR; high vs. average risk groups): 1.72 [1.37, 2.16]
PPM000477 PGS000157 (cGRS_Melanoma) PSS000277 PGP000075
Shi Z et al. (2019)
Reported Trait: Melanoma Mean realative risk: 1.2 [1.14, 1.26]
Wilcoxon test (case vs. control) p-value: 5.99e-11
PPM000489 PGS000158 (cGRS_Ovarian) PSS000278 PGP000075
Shi Z et al. (2019)
Reported Trait: Ovarian cancer Odds Ratio (OR; high vs. average risk groups): 1.63 [1.3, 2.06]
PPM000478 PGS000158 (cGRS_Ovarian) PSS000278 PGP000075
Shi Z et al. (2019)
Reported Trait: Ovarian cancer Mean realative risk: 1.12 [1.08, 1.16]
Wilcoxon test (case vs. control) p-value: 0.00015
PPM000490 PGS000159 (cGRS_Pancreatic) PSS000279 PGP000075
Shi Z et al. (2019)
Reported Trait: Pancreatic cancer Odds Ratio (OR; high vs. average risk groups): 1.67 [1.1, 2.53]
PPM000479 PGS000159 (cGRS_Pancreatic) PSS000279 PGP000075
Shi Z et al. (2019)
Reported Trait: Pancreatic cancer Mean realative risk: 1.13 [1.07, 1.18]
Wilcoxon test (case vs. control) p-value: 0.00015
PPM000491 PGS000160 (cGRS_Prostate) PSS000280 PGP000075
Shi Z et al. (2019)
Reported Trait: Prostate cancer Odds Ratio (OR; high vs. average risk groups): 1.73 [1.38, 2.17]
PPM000480 PGS000160 (cGRS_Prostate) PSS000280 PGP000075
Shi Z et al. (2019)
Reported Trait: Prostate cancer Mean realative risk: 1.3 [1.21, 1.38]
Wilcoxon test (case vs. control) p-value: 2.07e-18
PPM000492 PGS000161 (cGRS_Renal) PSS000281 PGP000075
Shi Z et al. (2019)
Reported Trait: Renal cancer Odds Ratio (OR; high vs. average risk groups): 1.58 [1.14, 2.18]
PPM000481 PGS000161 (cGRS_Renal) PSS000281 PGP000075
Shi Z et al. (2019)
Reported Trait: Renal cancer Mean realative risk: 1.09 [1.06, 1.12]
Wilcoxon test (case vs. control) p-value: 8.66e-10
PPM000493 PGS000162 (cGRS_Thyroid) PSS000282 PGP000075
Shi Z et al. (2019)
Reported Trait: Thyroid cancer Odds Ratio (OR; high vs. average risk groups): 1.7 [1.29, 2.25]
PPM000482 PGS000162 (cGRS_Thyroid) PSS000282 PGP000075
Shi Z et al. (2019)
Reported Trait: Thyroid cancer Mean realative risk: 1.09 [1.04, 1.15]
Wilcoxon test (case vs. control) p-value: 4e-05
PPM000631 PGS000207 (TC10_Ohio) PSS000342 PGP000085
Liyanarachchi S et al. (2020)
Reported Trait: Thyroid cancer AUROC: 0.692 [0.673, 0.71] gender, birth year, family history of disease (1st or 2nd degree relative) AUROC (Clinical factors alone) = 0.585 [0.565 - 0.605]
PPM000632 PGS000208 (TC10_Iceland) PSS000341 PGP000085
Liyanarachchi S et al. (2020)
Reported Trait: Thyroid cancer AUROC: 0.751 [0.736, 0.768] gender, birth year, family history of disease (1st or 2nd degree relative) AUROC (Clinical factors alone) = 0.697 [0.680 - 0.714]
PPM000633 PGS000209 (TC10_UKB) PSS000343 PGP000085
Liyanarachchi S et al. (2020)
Reported Trait: Thyroid cancer AUROC: 0.694 [0.673, 0.716] gender, birth year AUROC (Clinical factors alone) = 0.629 [0.606 - 0.651]
PPM000649 PGS000212 (PRS330_LumA) PSS000360 PGP000088
Zhang H et al. (2020)
Reported Trait: Breast cancer intrinsic-like subtype (luminal A-like) OR: 1.83 [1.78, 1.88] AUROC: 0.6609
PPM000652 PGS000213 (PRS330_LumBHER2neg) PSS000361 PGP000088
Zhang H et al. (2020)
Reported Trait: Breast cancer intrinsic-like subtype (luminal B/HER2-negative-like) OR: 1.62 [1.54, 1.7] AUROC: 0.633
PPM000655 PGS000214 (PRS330_LumB) PSS000362 PGP000088
Zhang H et al. (2020)
Reported Trait: Breast cancer intrinsic-like subtype (luminal B-like) OR: 1.69 [1.61, 1.77] AUROC: 0.6431
PPM000658 PGS000215 (PRS330_HER2) PSS000359 PGP000088
Zhang H et al. (2020)
Reported Trait: Breast cancer intrinsic-like subtype (HER2-enriched-like) OR: 1.53 [1.42, 1.65] AUROC: 0.6208
PPM000661 PGS000216 (PRS330_TN) PSS000363 PGP000088
Zhang H et al. (2020)
Reported Trait: Breast cancer intrinsic-like subtype (triple negative) OR: 1.65 [1.57, 1.73] AUROC: 0.6358
PPM000849 PGS000317 (PRS180) PSS000407 PGP000094
Shieh Y et al. (2020)
Reported Trait: Breast cancer (Latin american women) OR: 1.54 [1.45, 1.63] AUROC: 0.62 [0.61, 0.64] study, genetic ancestry (ADMIXTURE)
PPM000848 PGS000317 (PRS180) PSS000408 PGP000094
Shieh Y et al. (2020)
Reported Trait: Breast cancer (US Latinas) OR: 1.62 [1.52, 1.71] AUROC: 0.63 [0.62, 0.65] study, genetic ancestry (ADMIXTURE)
PPM000847 PGS000317 (PRS180) PSS000406 PGP000094
Shieh Y et al. (2020)
Reported Trait: Breast cancer OR: 1.7 [1.63, 1.78]
PPM000846 PGS000317 (PRS180) PSS000406 PGP000094
Shieh Y et al. (2020)
Reported Trait: Breast cancer OR: 1.58 [1.52, 1.64] AUROC: 0.63 [0.62, 0.64] study, genetic ancestry (ADMIXTURE)
PPM000899 PGS000332 (PRS_BC) PSS000444 PGP000100
Mars N et al. (2020)
Reported Trait: Incident breast cancer C-index: 0.75 age, family history of breast cancer, current smoking, BMI, alcohol use disorder, years of hormone replacement therapy, having given birth to one or more children, genotyping array/batch, 10 ancestry PCs 10-year risk
PPM000894 PGS000332 (PRS_BC) PSS000444 PGP000100
Mars N et al. (2020)
Reported Trait: Incident breast cancer C-index: 0.737 age, genotyping array/batch, 10 ancestry PCs 10-year risk
PPM000889 PGS000332 (PRS_BC) PSS000443 PGP000100
Mars N et al. (2020)
Reported Trait: Breast cancer (incident and prevalent cases) HR: 1.64 [1.6, 1.69] genotyping array/batch, 10 ancestry PCs
PPM001346 PGS000332 (PRS_BC) PSS000450 PGP000102
Mars N et al. (2020)
Ext.
Reported Trait: Breast cancer HR: 1.63 [1.6, 1.67] 10 ancestry PCs, batch, age as time scale
PPM001348 PGS000332 (PRS_BC) PSS000450 PGP000102
Mars N et al. (2020)
Ext.
Reported Trait: Breast cancer OR: 1.71 [1.67, 1.75] Age, 10 ancestry PCs, batch
PPM000900 PGS000333 (PRS_PC) PSS000447 PGP000100
Mars N et al. (2020)
Reported Trait: Incident prostate cancer C-index: 0.866 age, family history, history of benign prostate hyperplasia, genotyping array/batch, 10 ancestry PCs 10-year risk
PPM000895 PGS000333 (PRS_PC) PSS000447 PGP000100
Mars N et al. (2020)
Reported Trait: Incident prostate cancer C-index: 0.857 age, genotyping array/batch, 10 ancestry PCs 10-year risk
PPM000890 PGS000333 (PRS_PC) PSS000446 PGP000100
Mars N et al. (2020)
Reported Trait: Prostate cancer (incident and prevalent cases) HR: 1.83 [1.78, 1.9] genotyping array/batch, 10 ancestry PCs
PPM000903 PGS000335 (BC_PRSCS) PSS000450 PGP000102
Mars N et al. (2020)
Reported Trait: Breast cancer OR: 1.8 [1.76, 1.84] Age, 10 ancestry PCs, batch
PPM000902 PGS000335 (BC_PRSCS) PSS000450 PGP000102
Mars N et al. (2020)
Reported Trait: Breast cancer HR: 1.71 [1.68, 1.75] 10 ancestry PCs, batch, age as time scale
PPM000922 PGS000339 (PRS22_CM) PSS000464 PGP000106
Law MH et al. (2020)
Reported Trait: Cutaneous melanoma in multiplex melanoma families Difference of PRS (deltaPRS; unaffected melanoma family members vs. unrelated controls): 0.347 (0.104) PCs (1-10) *Sample overlap between the controls used in this analysis and score development
PPM000921 PGS000339 (PRS22_CM) PSS000463 PGP000106
Law MH et al. (2020)
Reported Trait: Cutaneous melanoma in multiplex melanoma families Difference of PRS (deltaPRS; melanoma family cases vs. unrelated controls): 0.505 (0.036) PCs (1-10) *Sample overlap between the controls used in this analysis and score development
PPM000979 PGS000344 (PRS287_BC) PSS000497 PGP000112
Ho WK et al. (2020)
Reported Trait: Breast cancer OR: 1.36 [1.25, 1.49] AUROC: 0.577 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000976 PGS000344 (PRS287_BC) PSS000494 PGP000112
Ho WK et al. (2020)
Reported Trait: Breast cancer OR: 1.55 [1.5, 1.61] PCs (1-10), study, array,batch
PPM000973 PGS000344 (PRS287_BC) PSS000491 PGP000112
Ho WK et al. (2020)
Reported Trait: Breast cancer OR: 1.52 [1.49, 1.56] AUROC: 0.613 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000983 PGS000345 (PRS229_BC) PSS000491 PGP000112
Ho WK et al. (2020)
Reported Trait: Breast cancer OR: 1.49 [1.45, 1.52] AUROC: 0.611 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000982 PGS000345 (PRS229_BC) PSS000500 PGP000112
Ho WK et al. (2020)
Reported Trait: Incident breast cancer HR: 1.49 [1.33, 1.67] C-index: 0.61 PCs (1-7), study, array,batch Standardised to SDs of PRs in European controls
PPM000984 PGS000345 (PRS229_BC) PSS000497 PGP000112
Ho WK et al. (2020)
Reported Trait: Breast cancer OR: 1.33 [1.22, 1.45] AUROC: 0.579 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000981 PGS000346 (PRS287_ERneg) PSS000498 PGP000112
Ho WK et al. (2020)
Reported Trait: ER-negative breast cancer OR: 1.49 [1.26, 1.75] AUROC: 0.587 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000978 PGS000346 (PRS287_ERneg) PSS000495 PGP000112
Ho WK et al. (2020)
Reported Trait: ER-negative breast cancer OR: 1.43 [1.35, 1.52] PCs (1-10), study, array,batch
PPM000975 PGS000346 (PRS287_ERneg) PSS000493 PGP000112
Ho WK et al. (2020)
Reported Trait: ER-negative breast cancer OR: 1.41 [1.36, 1.46] AUROC: 0.594 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000980 PGS000347 (PRS287_ERpos) PSS000499 PGP000112
Ho WK et al. (2020)
Reported Trait: ER-positive breast cancer OR: 1.38 [1.25, 1.53] AUROC: 0.586 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000977 PGS000347 (PRS287_ERpos) PSS000496 PGP000112
Ho WK et al. (2020)
Reported Trait: ER-positive breast cancer OR: 1.59 [1.53, 1.66] PCs (1-10), study, array,batch
PPM000974 PGS000347 (PRS287_ERpos) PSS000492 PGP000112
Ho WK et al. (2020)
Reported Trait: ER-positive breast cancer OR: 1.62 [1.57, 1.67] AUROC: 0.627 PCs (1-10), study, array,batch Standardised to SDs of PRs in European controls
PPM000987 PGS000348 (PRS_PrCa) PSS000502 PGP000113
Black MH et al. (2020)
Reported Trait: Prostate cancer in men with a family history of prostate cancer OR: 1.9 [1.53, 2.4] Age
PPM000986 PGS000348 (PRS_PrCa) PSS000501 PGP000113
Black MH et al. (2020)
Reported Trait: Prostate cancer AUROC: 0.64 Age
PPM000985 PGS000348 (PRS_PrCa) PSS000501 PGP000113
Black MH et al. (2020)
Reported Trait: Prostate cancer OR: 1.72 [1.59, 1.88] AUROC: 0.64 [0.62, 0.66]
PPM000988 PGS000348 (PRS_PrCa) PSS000503 PGP000113
Black MH et al. (2020)
Reported Trait: Prostate cancer in men with no family history of prostate cancer OR: 1.65 [1.49, 1.84] Age
PPM001030 PGS000351 (PRS_EOC) PSS000524 PGP000117
Barnes DR et al. (2020)
Reported Trait: Ovarian cancer in BRCA1 carriers HR: 1.31 [1.24, 1.39] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001031 PGS000351 (PRS_EOC) PSS000528 PGP000117
Barnes DR et al. (2020)
Reported Trait: Ovarian cancer in BRCA2 carriers HR: 1.42 [1.28, 1.58] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001032 PGS000352 (PRS_HGS) PSS000524 PGP000117
Barnes DR et al. (2020)
Reported Trait: Ovarian cancer in BRCA1 carriers HR: 1.32 [1.25, 1.4] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001033 PGS000352 (PRS_HGS) PSS000528 PGP000117
Barnes DR et al. (2020)
Reported Trait: Ovarian cancer in BRCA2 carriers HR: 1.43 [1.29, 1.59] birth cohort, PCs(1-4) of ancestry, family history in first- and second-degree relatives
PPM001036 PGS000352 (PRS_HGS) PSS000530 PGP000117
Barnes DR et al. (2020)
Reported Trait: Incident ovarian cancer in BRCA1 carriers HR: 1.28 [1.06, 1.55] family history of the appropriate cancer in first- and second-degree relatives
PPM001037 PGS000352 (PRS_HGS) PSS000532 PGP000117
Barnes DR et al. (2020)
Reported Trait: Incident ovarian cancer in BRCA2 carriers HR: 1.45 [1.13, 1.86] family history of the appropriate cancer in first- and second-degree relatives
PPM001038 PGS000353 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.08 [1.041, 1.122]
β: 0.0774 (0.0191)
AUROC: 0.515 [0.503, 0.526] Nagelkerke's Pseudo-R²: 0.00151
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.48 [1.04, 2.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608
PPM001039 PGS000354 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PRS-CS_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.079 [1.039, 1.119]
β: 0.0758 (0.0189)
AUROC: 0.521 [0.51, 0.532] Nagelkerke's Pseudo-R²: 0.00112
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.27 [0.887, 1.81]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PRS-CS_MGI_20200608
PPM001040 PGS000355 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.084 [1.044, 1.125]
β: 0.0803 (0.0191)
AUROC: 0.517 [0.506, 0.527] Nagelkerke's Pseudo-R²: 0.00167
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.42 [1.0, 2.02]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608
PPM001041 PGS000356 (PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608) PSS000533 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Any Cancer OR: 1.106 [1.065, 1.148]
β: 0.101 (0.0192)
AUROC: 0.523 [0.512, 0.535] Nagelkerke's Pseudo-R²: 0.00294
Brier score: 0.182
Odds Ratio (OR, top 1% vs. Rest): 1.61 [1.14, 2.27]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608
PPM001042 PGS000357 (PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608) PSS000535 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of mouth OR: 1.111 [1.021, 1.208]
β: 0.105 (0.0427)
AUROC: 0.519 [0.498, 0.542] Nagelkerke's Pseudo-R²: 0.0021
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.26 [0.585, 2.73]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608
PPM001043 PGS000358 (PRSWEB_PHECODE145_UKBB-SAIGE-HRC-X145_PRS-CS_MGI_20200608) PSS000535 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of mouth OR: 1.116 [1.024, 1.216]
β: 0.11 (0.0438)
AUROC: 0.528 [0.502, 0.552] Nagelkerke's Pseudo-R²: 0.00207
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.63 [0.812, 3.26]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE145_UKBB-SAIGE-HRC-X145_PRS-CS_MGI_20200608
PPM001045 PGS000360 (PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608) PSS000536 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of larynx OR: 1.282 [1.09, 1.508]
β: 0.249 (0.0827)
AUROC: 0.57 [0.522, 0.618] Nagelkerke's Pseudo-R²: 0.0112
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 2.14 [0.649, 7.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE149.4_C32_LASSOSUM_MGI_20200608
PPM001046 PGS000361 (PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608) PSS000536 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of larynx OR: 1.195 [1.014, 1.408]
β: 0.178 (0.0836)
AUROC: 0.55 [0.504, 0.593] Nagelkerke's Pseudo-R²: 0.00551
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.51 [0.382, 5.94]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE149.4_C3-LARYNX_LASSOSUM_MGI_20200608
PPM001047 PGS000362 (PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608) PSS000536 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of larynx OR: 1.195 [1.023, 1.396]
β: 0.178 (0.0793)
AUROC: 0.543 [0.494, 0.59] Nagelkerke's Pseudo-R²: 0.00609
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.52 [0.384, 5.98]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE149.4_UKBB-SAIGE-HRC-X149.4_PT_MGI_20200608
PPM001048 PGS000363 (PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.249 [1.075, 1.45]
β: 0.222 (0.0762)
AUROC: 0.564 [0.525, 0.604] Nagelkerke's Pseudo-R²: 0.0089
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 2.84 [1.07, 7.54]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608
PPM001049 PGS000364 (PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.203 [1.041, 1.391]
β: 0.185 (0.074)
AUROC: 0.551 [0.51, 0.588] Nagelkerke's Pseudo-R²: 0.00648
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.81 [0.56, 5.82]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608
PPM001050 PGS000365 (PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.187 [1.021, 1.38]
β: 0.171 (0.0769)
AUROC: 0.553 [0.514, 0.596] Nagelkerke's Pseudo-R²: 0.00521
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 1.27 [0.329, 4.9]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608
PPM001051 PGS000366 (PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608) PSS000537 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of esophagus OR: 1.24 [1.067, 1.441]
β: 0.215 (0.0766)
AUROC: 0.564 [0.522, 0.605] Nagelkerke's Pseudo-R²: 0.00839
Brier score: 0.0825
Odds Ratio (OR, top 1% vs. Rest): 1.28 [0.332, 4.95]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608
PPM001052 PGS000367 (PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.198 [1.102, 1.302]
β: 0.181 (0.0425)
AUROC: 0.55 [0.522, 0.574] Nagelkerke's Pseudo-R²: 0.00586
Brier score: 0.0828
Odds Ratio (OR, top 1% vs. Rest): 2.2 [1.21, 4.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_MGI_20200608
PPM001053 PGS000368 (PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.516 [1.451, 1.585]
β: 0.416 (0.0225)
AUROC: 0.612 [0.6, 0.625] Nagelkerke's Pseudo-R²: 0.0304
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.85 [2.99, 4.96]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608
PPM001054 PGS000369 (PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.214 [1.117, 1.32]
β: 0.194 (0.0426)
AUROC: 0.553 [0.525, 0.577] Nagelkerke's Pseudo-R²: 0.00671
Brier score: 0.0828
Odds Ratio (OR, top 1% vs. Rest): 3.04 [1.79, 5.17]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608
PPM001055 PGS000370 (PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.547 [1.48, 1.617]
β: 0.436 (0.0226)
AUROC: 0.617 [0.605, 0.63] Nagelkerke's Pseudo-R²: 0.0332
Brier score: 0.0812
Odds Ratio (OR, top 1% vs. Rest): 4.0 [3.11, 5.13]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608
PPM001056 PGS000371 (PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.254 [1.202, 1.309]
β: 0.226 (0.0217)
AUROC: 0.561 [0.548, 0.573] Nagelkerke's Pseudo-R²: 0.00946
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 1.79 [1.28, 2.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608
PPM001057 PGS000372 (PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608) PSS000564 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.279 [1.225, 1.335]
β: 0.246 (0.0218)
AUROC: 0.565 [0.551, 0.577] Nagelkerke's Pseudo-R²: 0.0111
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 2.1 [1.53, 2.89]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608
PPM001058 PGS000373 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PRS-CS_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.189 [1.093, 1.293]
β: 0.173 (0.0428)
AUROC: 0.548 [0.523, 0.572] Nagelkerke's Pseudo-R²: 0.00529
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.71 [0.882, 3.33]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PRS-CS_MGI_20200608
PPM001059 PGS000374 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.091 [1.004, 1.185]
β: 0.0872 (0.0423)
AUROC: 0.517 [0.493, 0.541] Nagelkerke's Pseudo-R²: 0.00134
Brier score: 0.083
Odds Ratio (OR, top 1% vs. Rest): 1.88 [0.99, 3.55]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608
PPM001060 PGS000375 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_LASSOSUM_MGI_20200608) PSS000540 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colorectal cancer OR: 1.113 [1.024, 1.21]
β: 0.107 (0.0425)
AUROC: 0.53 [0.503, 0.555] Nagelkerke's Pseudo-R²: 0.00205
Brier score: 0.083
Odds Ratio (OR, top 1% vs. Rest): 2.76 [1.59, 4.81]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_LASSOSUM_MGI_20200608
PPM001061 PGS000376 (PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.177 [1.069, 1.297]
β: 0.163 (0.0491)
AUROC: 0.547 [0.518, 0.576] Nagelkerke's Pseudo-R²: 0.0046
Brier score: 0.0832
Odds Ratio (OR, top 1% vs. Rest): 1.65 [0.753, 3.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608
PPM001062 PGS000377 (PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.174 [1.066, 1.292]
β: 0.16 (0.049)
AUROC: 0.545 [0.518, 0.574] Nagelkerke's Pseudo-R²: 0.00441
Brier score: 0.0831
Odds Ratio (OR, top 1% vs. Rest): 1.4 [0.607, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608
PPM001063 PGS000378 (PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.141 [1.038, 1.254]
β: 0.132 (0.0484)
AUROC: 0.536 [0.509, 0.565] Nagelkerke's Pseudo-R²: 0.00301
Brier score: 0.0832
Odds Ratio (OR, top 1% vs. Rest): 1.82 [0.867, 3.84]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608
PPM001064 PGS000379 (PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.143 [1.038, 1.258]
β: 0.134 (0.049)
AUROC: 0.536 [0.51, 0.567] Nagelkerke's Pseudo-R²: 0.00302
Brier score: 0.0832
Odds Ratio (OR, top 1% vs. Rest): 0.757 [0.252, 2.28]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608
PPM001065 PGS000380 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.324 [1.203, 1.457]
β: 0.281 (0.0489)
AUROC: 0.569 [0.539, 0.599] Nagelkerke's Pseudo-R²: 0.0138
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 3.85 [2.19, 6.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608
PPM001066 PGS000381 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.212 [1.105, 1.33]
β: 0.193 (0.0472)
AUROC: 0.55 [0.522, 0.577] Nagelkerke's Pseudo-R²: 0.00703
Brier score: 0.0831
Odds Ratio (OR, top 1% vs. Rest): 1.6 [0.733, 3.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608
PPM001067 PGS000382 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608) PSS000538 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Colon cancer OR: 1.247 [1.134, 1.371]
β: 0.221 (0.0483)
AUROC: 0.567 [0.54, 0.594] Nagelkerke's Pseudo-R²: 0.00899
Brier score: 0.083
Odds Ratio (OR, top 1% vs. Rest): 1.17 [0.477, 2.87]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608
PPM001068 PGS000383 (PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608) PSS000539 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of rectum, rectosigmoid junction, and anus OR: 1.126 [1.005, 1.262]
β: 0.119 (0.0579)
AUROC: 0.533 [0.5, 0.567] Nagelkerke's Pseudo-R²: 0.00257
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.34 [0.491, 3.65]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608
PPM001069 PGS000384 (PRSWEB_PHECODE153.3_C3-RECTUM_PRS-CS_MGI_20200608) PSS000539 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Malignant neoplasm of rectum, rectosigmoid junction, and anus OR: 1.122 [1.001, 1.257]
β: 0.115 (0.058)
AUROC: 0.531 [0.495, 0.563] Nagelkerke's Pseudo-R²: 0.00251
Brier score: 0.0829
Odds Ratio (OR, top 1% vs. Rest): 1.02 [0.334, 3.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE153.3_C3-RECTUM_PRS-CS_MGI_20200608
PPM001070 PGS000385 (PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608) PSS000565 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Pancreatic cancer OR: 1.384 [1.235, 1.552]
β: 0.325 (0.0583)
AUROC: 0.589 [0.559, 0.622] Nagelkerke's Pseudo-R²: 0.019
Brier score: 0.082
Odds Ratio (OR, top 1% vs. Rest): 2.58 [1.19, 5.57]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608
PPM001071 PGS000386 (PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_PT_UKB_20200608) PSS000565 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Pancreatic cancer OR: 1.342 [1.199, 1.503]
β: 0.294 (0.0577)
AUROC: 0.579 [0.548, 0.611] Nagelkerke's Pseudo-R²: 0.0157
Brier score: 0.0822
Odds Ratio (OR, top 1% vs. Rest): 1.64 [0.655, 4.12]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_PT_UKB_20200608
PPM001072 PGS000387 (PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608) PSS000542 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer within the respiratory system OR: 1.109 [1.008, 1.22]
β: 0.103 (0.0486)
AUROC: 0.53 [0.502, 0.557] Nagelkerke's Pseudo-R²: 0.0018
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.22 [1.12, 4.37]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165_UKBB-SAIGE-HRC-X165_LASSOSUM_MGI_20200608
PPM001073 PGS000388 (PRSWEB_PHECODE165.1_C3-BRONCHUS-LUNG_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.132 [1.024, 1.25]
β: 0.124 (0.0508)
AUROC: 0.533 [0.505, 0.562] Nagelkerke's Pseudo-R²: 0.00265
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.96 [0.926, 4.14]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_C3-BRONCHUS-LUNG_PRS-CS_MGI_20200608
PPM001074 PGS000389 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.11 [1.006, 1.225]
β: 0.105 (0.0501)
AUROC: 0.52 [0.492, 0.547] Nagelkerke's Pseudo-R²: 0.00202
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 2.19 [1.07, 4.49]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_MGI_20200608
PPM001075 PGS000390 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_UKB_20200608) PSS000566 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.194 [1.124, 1.269]
β: 0.178 (0.0309)
AUROC: 0.543 [0.526, 0.562] Nagelkerke's Pseudo-R²: 0.00583
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 0.852 [0.437, 1.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_P_5e-08_UKB_20200608
PPM001076 PGS000391 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.12 [1.015, 1.237]
β: 0.114 (0.0507)
AUROC: 0.529 [0.503, 0.558] Nagelkerke's Pseudo-R²: 0.00234
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.75 [0.796, 3.85]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608
PPM001077 PGS000392 (PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_UKB_20200608) PSS000566 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.221 [1.149, 1.298]
β: 0.2 (0.0313)
AUROC: 0.552 [0.534, 0.569] Nagelkerke's Pseudo-R²: 0.00728
Brier score: 0.0824
Odds Ratio (OR, top 1% vs. Rest): 1.94 [1.22, 3.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_UKB_20200608
PPM001078 PGS000393 (PRSWEB_PHECODE165.1_LUNG-CANCER_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.149 [1.04, 1.269]
β: 0.139 (0.0509)
AUROC: 0.539 [0.508, 0.568] Nagelkerke's Pseudo-R²: 0.00329
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.18 [1.06, 4.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_LUNG-CANCER_PRS-CS_MGI_20200608
PPM001079 PGS000394 (PRSWEB_PHECODE165.1_LUNG-CANCER-MESOT_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.149 [1.04, 1.269]
β: 0.139 (0.0509)
AUROC: 0.539 [0.508, 0.568] Nagelkerke's Pseudo-R²: 0.00329
Brier score: 0.0826
Odds Ratio (OR, top 1% vs. Rest): 2.18 [1.06, 4.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_LUNG-CANCER-MESOT_PRS-CS_MGI_20200608
PPM001080 PGS000395 (PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PRS-CS_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.133 [1.025, 1.252]
β: 0.125 (0.051)
AUROC: 0.533 [0.505, 0.562] Nagelkerke's Pseudo-R²: 0.00277
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.27 [0.514, 3.12]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PRS-CS_MGI_20200608
PPM001081 PGS000396 (PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PT_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.121 [1.015, 1.238]
β: 0.114 (0.0507)
AUROC: 0.525 [0.496, 0.554] Nagelkerke's Pseudo-R²: 0.00233
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 2.21 [1.08, 4.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_PT_MGI_20200608
PPM001082 PGS000397 (PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_LASSOSUM_MGI_20200608) PSS000541 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Cancer of bronchus; lung OR: 1.114 [1.009, 1.23]
β: 0.108 (0.0507)
AUROC: 0.528 [0.503, 0.556] Nagelkerke's Pseudo-R²: 0.00202
Brier score: 0.0827
Odds Ratio (OR, top 1% vs. Rest): 1.03 [0.387, 2.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE165.1_UKBB-SAIGE-HRC-X165.1_LASSOSUM_MGI_20200608
PPM001083 PGS000398 (PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.042 [1.003, 1.082]
β: 0.0407 (0.0195)
AUROC: 0.51 [0.499, 0.521] Nagelkerke's Pseudo-R²: 0.00028
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 1.7 [1.22, 2.38]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608
PPM001084 PGS000399 (PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.158 [1.116, 1.202]
β: 0.147 (0.0189)
AUROC: 0.513 [0.503, 0.523] Nagelkerke's Pseudo-R²: 0.00545
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 1.56 [1.12, 2.16]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608
PPM001085 PGS000400 (PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.342 [1.291, 1.395]
β: 0.294 (0.0197)
AUROC: 0.581 [0.57, 0.592] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.2 [1.63, 2.98]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608
PPM001086 PGS000401 (PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.342 [1.291, 1.396]
β: 0.294 (0.0199)
AUROC: 0.581 [0.57, 0.591] Nagelkerke's Pseudo-R²: 0.0202
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.25 [1.67, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608
PPM001087 PGS000402 (PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.366 [1.314, 1.421]
β: 0.312 (0.0198)
AUROC: 0.586 [0.576, 0.597] Nagelkerke's Pseudo-R²: 0.0224
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.23 [1.64, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608
PPM001088 PGS000403 (PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.359 [1.307, 1.413]
β: 0.307 (0.0199)
AUROC: 0.584 [0.573, 0.594] Nagelkerke's Pseudo-R²: 0.0219
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.2, 2.27]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608
PPM001089 PGS000404 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.369 [1.317, 1.422]
β: 0.314 (0.0196)
AUROC: 0.584 [0.574, 0.594] Nagelkerke's Pseudo-R²: 0.0226
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.3 [1.72, 3.09]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608
PPM001090 PGS000405 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.338 [1.287, 1.391]
β: 0.291 (0.0199)
AUROC: 0.58 [0.57, 0.591] Nagelkerke's Pseudo-R²: 0.0192
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.42 [1.81, 3.24]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608
PPM001091 PGS000406 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.392 [1.339, 1.447]
β: 0.331 (0.0199)
AUROC: 0.591 [0.581, 0.602] Nagelkerke's Pseudo-R²: 0.0249
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.51 [1.89, 3.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608
PPM001092 PGS000407 (PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608) PSS000548 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Skin cancer OR: 1.38 [1.328, 1.434]
β: 0.322 (0.0197)
AUROC: 0.586 [0.575, 0.597] Nagelkerke's Pseudo-R²: 0.0245
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.26 [1.69, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608
PPM001093 PGS000408 (PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.384 [1.311, 1.461]
β: 0.325 (0.0276)
AUROC: 0.576 [0.561, 0.593] Nagelkerke's Pseudo-R²: 0.0217
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 2.25 [1.48, 3.42]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_P_5e-08_MGI_20200608
PPM001094 PGS000409 (PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.192 [1.126, 1.263]
β: 0.176 (0.0292)
AUROC: 0.547 [0.531, 0.563] Nagelkerke's Pseudo-R²: 0.0061
Brier score: 0.0966
Odds Ratio (OR, top 1% vs. Rest): 1.94 [1.25, 3.02]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608
PPM001095 PGS000410 (PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.399 [1.327, 1.476]
β: 0.336 (0.0272)
AUROC: 0.578 [0.562, 0.594] Nagelkerke's Pseudo-R²: 0.0239
Brier score: 0.0956
Odds Ratio (OR, top 1% vs. Rest): 2.65 [1.79, 3.93]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608
PPM001096 PGS000411 (PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.378 [1.308, 1.451]
β: 0.32 (0.0265)
AUROC: 0.571 [0.555, 0.587] Nagelkerke's Pseudo-R²: 0.0222
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 2.0 [1.29, 3.09]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608
PPM001097 PGS000412 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.414 [1.338, 1.495]
β: 0.347 (0.0282)
AUROC: 0.585 [0.569, 0.6] Nagelkerke's Pseudo-R²: 0.0236
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 3.26 [2.26, 4.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608
PPM001098 PGS000413 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.27 [1.199, 1.346]
β: 0.239 (0.0294)
AUROC: 0.568 [0.552, 0.584] Nagelkerke's Pseudo-R²: 0.0109
Brier score: 0.0964
Odds Ratio (OR, top 1% vs. Rest): 2.09 [1.35, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608
PPM001099 PGS000414 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.44 [1.363, 1.522]
β: 0.365 (0.0283)
AUROC: 0.593 [0.576, 0.609] Nagelkerke's Pseudo-R²: 0.026
Brier score: 0.0954
Odds Ratio (OR, top 1% vs. Rest): 2.97 [2.02, 4.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PT_MGI_20200608
PPM001100 PGS000415 (PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.391 [1.318, 1.467]
β: 0.33 (0.0272)
AUROC: 0.578 [0.562, 0.595] Nagelkerke's Pseudo-R²: 0.0227
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 2.34 [1.55, 3.53]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_LASSOSUM_MGI_20200608
PPM001101 PGS000416 (PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.473 [1.394, 1.557]
β: 0.388 (0.0282)
AUROC: 0.598 [0.582, 0.613] Nagelkerke's Pseudo-R²: 0.0297
Brier score: 0.0952
Odds Ratio (OR, top 1% vs. Rest): 2.88 [1.96, 4.21]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608
PPM001102 PGS000417 (PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.228 [1.159, 1.3]
β: 0.205 (0.0294)
AUROC: 0.556 [0.541, 0.571] Nagelkerke's Pseudo-R²: 0.00812
Brier score: 0.0965
Odds Ratio (OR, top 1% vs. Rest): 1.88 [1.2, 2.95]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608
PPM001103 PGS000418 (PRSWEB_PHECODE172.1_C43_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.473 [1.394, 1.557]
β: 0.388 (0.0282)
AUROC: 0.598 [0.582, 0.613] Nagelkerke's Pseudo-R²: 0.0297
Brier score: 0.0952
Odds Ratio (OR, top 1% vs. Rest): 2.88 [1.96, 4.21]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_PT_MGI_20200608
PPM001104 PGS000419 (PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.348 [1.279, 1.421]
β: 0.299 (0.0268)
AUROC: 0.565 [0.549, 0.583] Nagelkerke's Pseudo-R²: 0.0188
Brier score: 0.0959
Odds Ratio (OR, top 1% vs. Rest): 1.93 [1.24, 3.0]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_C43_LASSOSUM_MGI_20200608
PPM001105 PGS000420 (PRSWEB_PHECODE172.1_D03_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.066 [1.007, 1.128]
β: 0.0639 (0.029)
AUROC: 0.516 [0.5, 0.533] Nagelkerke's Pseudo-R²: 0.00074
Brier score: 0.0969
Odds Ratio (OR, top 1% vs. Rest): 1.07 [0.603, 1.9]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_D03_PT_MGI_20200608
PPM001106 PGS000421 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.453 [1.37, 1.541]
β: 0.374 (0.03)
AUROC: 0.6 [0.584, 0.616] Nagelkerke's Pseudo-R²: 0.0257
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 2.39 [1.58, 3.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608
PPM001107 PGS000422 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.539 [1.454, 1.629]
β: 0.431 (0.029)
AUROC: 0.615 [0.599, 0.63] Nagelkerke's Pseudo-R²: 0.0332
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.57 [1.75, 3.77]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_UKB_20200608
PPM001108 PGS000423 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx β: 0.394 (0.0301)
OR: 1.484 [1.399, 1.574]
AUROC: 0.608 [0.592, 0.623] Nagelkerke's Pseudo-R²: 0.0289
Brier score: 0.0954
Odds Ratio (OR, top 1% vs. Rest): 2.93 [2.0, 4.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608
PPM001109 PGS000424 (PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.563 [1.475, 1.656]
β: 0.447 (0.0294)
AUROC: 0.619 [0.603, 0.634] Nagelkerke's Pseudo-R²: 0.035
Brier score: 0.0812
Odds Ratio (OR, top 1% vs. Rest): 3.12 [2.18, 4.47]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608
PPM001110 PGS000425 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.453 [1.369, 1.542]
β: 0.374 (0.0304)
AUROC: 0.601 [0.585, 0.617] Nagelkerke's Pseudo-R²: 0.0255
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.7, 3.8]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_MGI_20200608
PPM001111 PGS000426 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.551 [1.463, 1.643]
β: 0.439 (0.0296)
AUROC: 0.62 [0.604, 0.635] Nagelkerke's Pseudo-R²: 0.0335
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.81 [1.93, 4.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_P_5e-08_UKB_20200608
PPM001112 PGS000427 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.453 [1.369, 1.542]
β: 0.374 (0.0304)
AUROC: 0.601 [0.585, 0.617] Nagelkerke's Pseudo-R²: 0.0255
Brier score: 0.0955
Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.7, 3.8]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_MGI_20200608
PPM001113 PGS000428 (PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_UKB_20200608) PSS000567 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.551 [1.463, 1.643]
β: 0.439 (0.0296)
AUROC: 0.62 [0.604, 0.635] Nagelkerke's Pseudo-R²: 0.0335
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.81 [1.93, 4.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_Melanoma-Ransohoff_PT_UKB_20200608
PPM001114 PGS000429 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.503 [1.422, 1.589]
β: 0.408 (0.0284)
AUROC: 0.606 [0.591, 0.622] Nagelkerke's Pseudo-R²: 0.0332
Brier score: 0.0951
Odds Ratio (OR, top 1% vs. Rest): 2.62 [1.77, 3.88]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608
PPM001115 PGS000430 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.219 [1.151, 1.292]
β: 0.198 (0.0296)
AUROC: 0.555 [0.54, 0.573] Nagelkerke's Pseudo-R²: 0.00721
Brier score: 0.0965
Odds Ratio (OR, top 1% vs. Rest): 1.64 [1.01, 2.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PRS-CS_MGI_20200608
PPM001116 PGS000431 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.486 [1.405, 1.571]
β: 0.396 (0.0285)
AUROC: 0.604 [0.587, 0.62] Nagelkerke's Pseudo-R²: 0.0312
Brier score: 0.0952
Odds Ratio (OR, top 1% vs. Rest): 2.97 [2.04, 4.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608
PPM001117 PGS000432 (PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608) PSS000543 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Melanomas of skin, dx or hx OR: 1.391 [1.318, 1.467]
β: 0.33 (0.0273)
AUROC: 0.582 [0.566, 0.599] Nagelkerke's Pseudo-R²: 0.0228
Brier score: 0.0957
Odds Ratio (OR, top 1% vs. Rest): 1.99 [1.29, 3.07]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_LASSOSUM_MGI_20200608
PPM001118 PGS000433 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.367 [1.31, 1.426]
β: 0.312 (0.0215)
AUROC: 0.584 [0.572, 0.598] Nagelkerke's Pseudo-R²: 0.0215
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.73 [2.01, 3.72]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608
PPM001119 PGS000434 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.361 [1.304, 1.42]
β: 0.308 (0.0217)
AUROC: 0.586 [0.573, 0.598] Nagelkerke's Pseudo-R²: 0.0208
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.99 [1.43, 2.78]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608
PPM001120 PGS000435 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.357 [1.301, 1.415]
β: 0.305 (0.0215)
AUROC: 0.584 [0.572, 0.597] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.7 [1.99, 3.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608
PPM001121 PGS000436 (PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.361 [1.305, 1.42]
β: 0.308 (0.0216)
AUROC: 0.584 [0.571, 0.596] Nagelkerke's Pseudo-R²: 0.021
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.22 [1.61, 3.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608
PPM001122 PGS000437 (PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.352 [1.296, 1.409]
β: 0.301 (0.0213)
AUROC: 0.579 [0.566, 0.592] Nagelkerke's Pseudo-R²: 0.0206
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.21 [1.6, 3.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608
PPM001123 PGS000438 (PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.31 [1.256, 1.367]
β: 0.27 (0.0216)
AUROC: 0.575 [0.562, 0.587] Nagelkerke's Pseudo-R²: 0.0162
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.79 [1.28, 2.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608
PPM001124 PGS000439 (PRSWEB_PHECODE172.2_C44_PT_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.348 [1.293, 1.407]
β: 0.299 (0.0216)
AUROC: 0.583 [0.57, 0.595] Nagelkerke's Pseudo-R²: 0.0197
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.17 [1.57, 3.01]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PT_MGI_20200608
PPM001125 PGS000440 (PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.351 [1.296, 1.409]
β: 0.301 (0.0215)
AUROC: 0.581 [0.569, 0.592] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.55 [1.87, 3.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608
PPM001126 PGS000441 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.39 [1.333, 1.449]
β: 0.329 (0.0214)
AUROC: 0.586 [0.574, 0.599] Nagelkerke's Pseudo-R²: 0.0241
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.65 [1.94, 3.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608
PPM001127 PGS000442 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.357 [1.301, 1.417]
β: 0.306 (0.0217)
AUROC: 0.584 [0.572, 0.595] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.35 [1.71, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608
PPM001128 PGS000443 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.41 [1.352, 1.471]
β: 0.344 (0.0216)
AUROC: 0.591 [0.579, 0.603] Nagelkerke's Pseudo-R²: 0.0259
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.89 [2.14, 3.92]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608
PPM001129 PGS000444 (PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608) PSS000546 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.399 [1.341, 1.46]
β: 0.336 (0.0216)
AUROC: 0.59 [0.578, 0.601] Nagelkerke's Pseudo-R²: 0.025
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.5 [2.63, 4.65]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608
PPM001130 PGS000445 (PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.334 [1.264, 1.409]
β: 0.289 (0.0278)
AUROC: 0.571 [0.555, 0.587] Nagelkerke's Pseudo-R²: 0.0184
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.72, 3.74]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608
PPM001131 PGS000446 (PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.291 [1.221, 1.366]
β: 0.256 (0.0286)
AUROC: 0.575 [0.559, 0.591] Nagelkerke's Pseudo-R²: 0.0139
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.871, 2.33]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608
PPM001132 PGS000447 (PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.398 [1.322, 1.477]
β: 0.335 (0.0282)
AUROC: 0.591 [0.575, 0.607] Nagelkerke's Pseudo-R²: 0.0237
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.5 [1.68, 3.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608
PPM001133 PGS000448 (PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.411 [1.335, 1.491]
β: 0.344 (0.0282)
AUROC: 0.587 [0.57, 0.604] Nagelkerke's Pseudo-R²: 0.0254
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.93 [2.03, 4.25]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608
PPM001134 PGS000449 (PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.093 [1.034, 1.155]
β: 0.0888 (0.0282)
AUROC: 0.525 [0.509, 0.54] Nagelkerke's Pseudo-R²: 0.00141
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.04, 2.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608
PPM001135 PGS000450 (PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.079 [1.022, 1.139]
β: 0.0759 (0.0278)
AUROC: 0.504 [0.489, 0.52] Nagelkerke's Pseudo-R²: 0.00145
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.882, 2.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608
PPM001136 PGS000451 (PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.144 [1.084, 1.208]
β: 0.135 (0.0278)
AUROC: 0.521 [0.506, 0.536] Nagelkerke's Pseudo-R²: 0.00396
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 2.44 [1.65, 3.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608
PPM001137 PGS000452 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.663 [1.57, 1.761]
β: 0.508 (0.0293)
AUROC: 0.632 [0.616, 0.647] Nagelkerke's Pseudo-R²: 0.0487
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.61 [2.53, 5.15]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608
PPM001138 PGS000453 (PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.511 [1.47, 1.554]
β: 0.413 (0.0142)
AUROC: 0.611 [0.604, 0.619] Nagelkerke's Pseudo-R²: 0.0301
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608
PPM001139 PGS000454 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.661 [1.568, 1.759]
β: 0.507 (0.0293)
AUROC: 0.632 [0.616, 0.647] Nagelkerke's Pseudo-R²: 0.0489
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.79 [2.68, 5.35]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608
PPM001140 PGS000455 (PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.511 [1.47, 1.554]
β: 0.413 (0.0142)
AUROC: 0.611 [0.604, 0.619] Nagelkerke's Pseudo-R²: 0.0301
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608
PPM001141 PGS000456 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.633 [1.541, 1.729]
β: 0.49 (0.0293)
AUROC: 0.63 [0.615, 0.646] Nagelkerke's Pseudo-R²: 0.0456
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.95 [2.79, 5.58]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608
PPM001142 PGS000457 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.535 [1.493, 1.579]
β: 0.429 (0.0144)
AUROC: 0.617 [0.609, 0.625] Nagelkerke's Pseudo-R²: 0.0322
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.11 [2.6, 3.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608
PPM001143 PGS000458 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608) PSS000544 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.634 [1.542, 1.732]
β: 0.491 (0.0296)
AUROC: 0.628 [0.612, 0.644] Nagelkerke's Pseudo-R²: 0.0457
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 4.03 [2.86, 5.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608
PPM001144 PGS000459 (PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608) PSS000568 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Basal cell carcinoma OR: 1.528 [1.485, 1.572]
β: 0.424 (0.0144)
AUROC: 0.615 [0.608, 0.623] Nagelkerke's Pseudo-R²: 0.0314
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.05 [2.55, 3.64]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608
PPM001145 PGS000460 (PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608) PSS000545 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.096 [1.025, 1.172]
β: 0.0917 (0.0344)
AUROC: 0.523 [0.503, 0.543] Nagelkerke's Pseudo-R²: 0.00155
Brier score: 0.0996
Odds Ratio (OR, top 1% vs. Rest): 1.56 [0.892, 2.74]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.22_20001-1062_LASSOSUM_MGI_20200608
PPM001146 PGS000461 (PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608) PSS000545 PGP000118
Fritsche LG et al. (2020)
Reported Trait: Squamous cell carcinoma OR: 1.491 [1.395, 1.593]
β: 0.4 (0.0338)
AUROC: 0.599 [0.579, 0.618]