| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0004531 |
| Description |
|
Trait category |
Other measurement
|
| Synonyms | urate levels |
| Mapped term(s) | NCIt:C64814 |
| Polygenic Score (PGS) ID | PGS Name | PGS Publication (PGP) ID | Reported Trait | Number of Variants | PGS Scoring File (FTP Link) |
|---|---|---|---|---|---|
| PGS000126 | Urate_GRS | PGP000063 Tin A et al. Nat Genet (2019) |
Serum urate | 114 | http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000126/ScoringFiles/PGS000126.txt.gz |
Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.
|
PGS Performance Metric ID (PPM ID) |
Evaluated Score |
PGS Sample Set ID (PSS ID) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
PGS Classification Metrics | Other Metrics | Covariates Included in the Model | PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM000406 | PGS000126 (Urate_GRS) | PSS000233 | PGP000063 Tin A et al. (2019) |
Reported Trait: Prevalent gout cases | — | AUROC: 0.84 | — | age, sex | — |
| PPM000405 | PGS000126 (Urate_GRS) | PSS000233 | PGP000063 Tin A et al. (2019) |
Reported Trait: Prevalent gout cases | — | AUROC: 0.67 | — | — | — |
|
PGS Sample Set ID (PSS ID) |
Detailed Phenotype Description | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS000233 | Gout identified by self-report at the inclusion visit, individuals with an ICD-10 for gout (M10) in hospital admissions who did not self-report gout were excluded from the analysis. | — | [
|
— | European | White British subset, unrelated | UKB | — |