Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000814
(GRS12_LDLc)
 PGP000200 |
Talmud PJ et al. Lancet (2013)
 LDL cholesterol low density lipoprotein cholesterol measurement 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000814/ScoringFiles/PGS000814.txt.gz
PGS000850
(T2D_Insulin_Action)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000959
(GBE_HC136)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Connective tissue disorder connective tissue disease 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000959/ScoringFiles/PGS000959.txt.gz
PGS000976
(GBE_BIN23066)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 JCV seropositivity for Human Polyomavirus JCV polyomavirus 2 seropositivity 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000976/ScoringFiles/PGS000976.txt.gz
PGS002278
(GRS16_snLVEF)
 PGP000307 |
Forrest IS et al. Eur J Heart Fail (2022)
 Supranormal left ventricular ejection fraction left ventricular ejection fraction measurement 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002278/ScoringFiles/PGS002278.txt.gz
PGS003185
(ExPRSweb_VitD_29343764-GCST005367_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003185/ScoringFiles/PGS003185.txt.gz
PGS003421
(PRS16_C+T)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz
PGS003422
(PRS16_PRSice2)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz
PGS003740
(PRS16_CU)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Corpus Uteri uterine corpus cancer 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003740/ScoringFiles/PGS003740.txt.gz
PGS004164
(PRS16_LC)
 PGP000518 |
Wei X et al. Int J Cancer (2023)
 Lung cancer in never smokers lung carcinoma,
smoking status measurement		 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004164/ScoringFiles/PGS004164.txt.gz
PGS004244
(PRS16_endometrium)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Endometrial cancer endometrial carcinoma 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004244/ScoringFiles/PGS004244.txt.gz
PGS004320
(PRS16_UGI)
 PGP000551 |
Liu W et al. Nutrients (2023)
 Upper gastrointestinal cancer Digestive System Carcinoma 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004320/ScoringFiles/PGS004320.txt.gz
PGS000037
(PGS_AST)
 PGP000025 |
Belsky DW et al. Lancet Respir Med (2013)
 Asthma asthma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000037/ScoringFiles/PGS000037.txt.gz
PGS000068
(PRS_EOC)
 PGP000048 |
Yang X et al. J Med Genet (2018)
 Epithelial ovarian cancer ovarian carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000068/ScoringFiles/PGS000068.txt.gz
PGS000069
(PRS_sEOC)
 PGP000048 |
Yang X et al. J Med Genet (2018)
 Serous epithelial ovarian cancer ovarian serous carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000069/ScoringFiles/PGS000069.txt.gz
PGS000071
(CC_Bladder)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Bladder cancer urinary bladder carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000071/ScoringFiles/PGS000071.txt.gz
PGS000355
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Any cancer cancer 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000355/ScoringFiles/PGS000355.txt.gz
PGS000431
(PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000431/ScoringFiles/PGS000431.txt.gz
PGS000555
(PRSWEB_PHECODE184.11_Phelan-LSASBOC_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000555/ScoringFiles/PGS000555.txt.gz
PGS000613
(PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000613/ScoringFiles/PGS000613.txt.gz
PGS000722
(PRS_Kidney)
 PGP000135 |
Jia G et al. JNCI Cancer Spectr (2020)
 Kidney cancer renal carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000722/ScoringFiles/PGS000722.txt.gz
PGS000782
(CC_Bladder_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Bladder cancer urinary bladder carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000782/ScoringFiles/PGS000782.txt.gz
PGS001348
(GBE_HC1584)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Alzheimer's disease (algorithmically-defined) Alzheimer disease 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001348/ScoringFiles/PGS001348.txt.gz
PGS001778
(PRS15_BC)
 PGP000259 |
Yiangou K et al. Cancers (Basel) (2021)
 Breast cancer breast carcinoma 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001778/ScoringFiles/PGS001778.txt.gz
PGS002283
(GRS15_NAFLD)
 PGP000312 |
Schnurr TM et al. Hepatol Commun (2022)
 Nonalcoholic fatty liver disease non-alcoholic fatty liver disease 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002283/ScoringFiles/PGS002283.txt.gz
PGS003181
(ExPRSweb_VitD_100021-raw_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003181/ScoringFiles/PGS003181.txt.gz
PGS003186
(ExPRSweb_VitD_29343764-GCST005367_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003186/ScoringFiles/PGS003186.txt.gz
PGS003305
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003305/ScoringFiles/PGS003305.txt.gz
PGS003306
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003306/ScoringFiles/PGS003306.txt.gz
PGS003448
(PRS15_ALL)
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Acute lymphoblastic leukemia acute lymphoblastic leukemia 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003448/ScoringFiles/PGS003448.txt.gz
PGS003717
(R_subiculum_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right subiculum body volume subiculum volume 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003717/ScoringFiles/PGS003717.txt.gz
PGS004227
(ad_apoe_gw_pgs)
 PGP000527 |
Green RE et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004227/ScoringFiles/PGS004227.txt.gz
PGS005165
(PRS-CC)
 PGP000711 |
Zhu M et al. PLoS Med (2025)
 Cervical cancer cervical carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005165/ScoringFiles/PGS005165.txt.gz
PGS005282
(GRS15_nephropathy)
 PGP000756 |
Xu L et al. Phenomics (2024)
 IgA nephropathy IGA glomerulonephritis 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005282/ScoringFiles/PGS005282.txt.gz
PGS000081
(CC_Oral)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Oral cavity and pharyngeal cancers oral cavity cancer,
pharynx cancer		 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000081/ScoringFiles/PGS000081.txt.gz
PGS000151
(SC_GRS)
 PGP000074 |
Xin J et al. Gene (2018)
 Colorectal cancer colorectal cancer 14
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000151/ScoringFiles/PGS000151.txt.gz
PGS000353
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Any cancer cancer 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000353/ScoringFiles/PGS000353.txt.gz
PGS000391
(PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Lung and bronchus cancer tracheal cancer,
bronchus cancer,
lung cancer		 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000391/ScoringFiles/PGS000391.txt.gz
PGS000464
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000464/ScoringFiles/PGS000464.txt.gz
PGS000522
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000522/ScoringFiles/PGS000522.txt.gz
PGS000723
(PRS_Bladder)
 PGP000135 |
Jia G et al. JNCI Cancer Spectr (2020)
 Bladder cancer urinary bladder carcinoma 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000723/ScoringFiles/PGS000723.txt.gz
PGS000731
(PRS_SCC)
 PGP000138 |
Fontanillas P et al. Nat Commun (2021)
 Squamous cell carcinoma squamous cell carcinoma 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000731/ScoringFiles/PGS000731.txt.gz - Check Terms/Licenses
PGS000755
(PRS_SUA)
 PGP000161 |
Cho SK et al. Sci Rep (2020)
 Serum uric acid levels uric acid measurement 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000755/ScoringFiles/PGS000755.txt.gz
PGS000767
(GRS14)
 PGP000174 |
Guffanti G et al. Transl Psychiatry (2019)
 Depression depressive symptom measurement,
major depressive disorder		 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000767/ScoringFiles/PGS000767.txt.gz
PGS000792
(CC_Oral_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Oral cavity and pharyngeal cancers oral cavity cancer,
pharynx cancer		 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000792/ScoringFiles/PGS000792.txt.gz
PGS000871
(IS_14)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Insulin secretion insulin secretion trait 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000871/ScoringFiles/PGS000871.txt.gz
PGS002298
(PRS14_esophageal)
 PGP000328 |
Choi J et al. Int J Cancer (2020)
 Esophageal cancer esophageal carcinoma 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002298/ScoringFiles/PGS002298.txt.gz
PGS002751
(GRSrare)
 PGP000363 |
Sapkota Y et al. Nat Med (2022)
 Body mass index (BMI) body mass index 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002751/ScoringFiles/PGS002751.txt.gz
PGS003419
(PRState_Trans)
 PGP000430 |
Pagadala MS et al. BMC Cancer (2022)
 Prostate cancer prostate cancer 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003419/ScoringFiles/PGS003419.txt.gz
PGS003447
(PRS14_endo)
 PGP000447 |
Kloeve-Mogensen K et al. Front Reprod Health (2021)
 Endometriosis endometriosis 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003447/ScoringFiles/PGS003447.txt.gz
Showing 4951 to 5000 of 5221 rows