Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS003566
(cont-decay-neutrophil_perc)
PGP000457 |
Ding Y et al. Nature (2023)
Neutrophil percentage neutrophil percentage of leukocytes 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003566/ScoringFiles/PGS003566.txt.gz
PGS003567
(cont-decay-reticulocyte_volume)
PGP000457 |
Ding Y et al. Nature (2023)
Mean reticulocyte volume mean reticulocyte volume 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003567/ScoringFiles/PGS003567.txt.gz
PGS003568
(cont-decay-sensitive_stomach)
PGP000457 |
Ding Y et al. Nature (2023)
Sensitive stomach health trait 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003568/ScoringFiles/PGS003568.txt.gz
PGS003569
(cont-decay-sitting_height)
PGP000457 |
Ding Y et al. Nature (2023)
Sitting height sitting height measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003569/ScoringFiles/PGS003569.txt.gz
PGS003570
(cont-decay-sphered_cell_volume)
PGP000457 |
Ding Y et al. Nature (2023)
Mean sphered cell volume erythrocyte volume 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003570/ScoringFiles/PGS003570.txt.gz
PGS003571
(cont-decay-systolic_BP)
PGP000457 |
Ding Y et al. Nature (2023)
Systolic blood pressure, automated reading systolic blood pressure 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003571/ScoringFiles/PGS003571.txt.gz
PGS003572
(cont-decay-urate)
PGP000457 |
Ding Y et al. Nature (2023)
Urate urate measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003572/ScoringFiles/PGS003572.txt.gz
PGS003573
(cont-decay-years_of_edu)
PGP000457 |
Ding Y et al. Nature (2023)
Qualifications (years of education) educational attainment 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003573/ScoringFiles/PGS003573.txt.gz
PGS002705
(blood_MEAN_CORPUSCULAR_HEMOGLOBIN.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean corpuscular hemoglobin mean corpuscular hemoglobin 979,778
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002705/ScoringFiles/PGS002705.txt.gz
PGS018930
(TPMI_292_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Neurological disorders nervous system disorder 980,061
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018930/ScoringFiles/PGS018930.txt.gz
PGS005364
(DPRISM_T2DPRS_trainedforEAS_AMRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 980,079
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005364/ScoringFiles/PGS005364.txt.gz
PGS019521
(TPMI_599.5_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Frequency of urination and polyuria Polyuria 980,241
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019521/ScoringFiles/PGS019521.txt.gz
PGS002707
(blood_MONOCYTE_COUNT.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Monocyte count monocyte count 980,307
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002707/ScoringFiles/PGS002707.txt.gz
PGS002691
(blood_EOSINOPHIL_COUNT.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Eosinophil count eosinophil count 980,421
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002691/ScoringFiles/PGS002691.txt.gz
PGS004065
(megaprs.auto.GCST90018959.Height)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Height body height 980,499
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004065/ScoringFiles/PGS004065.txt.gz
PGS002685
(cov_EDU_COLLEGE.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
College education educational attainment 980,529
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002685/ScoringFiles/PGS002685.txt.gz
PGS002714
(cov_SMOKING_STATUS.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Smoking status smoking status measurement 981,081
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002714/ScoringFiles/PGS002714.txt.gz
PGS005355
(DPRISM_T2DPRS_trainedforAFR_EASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 981,210
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005355/ScoringFiles/PGS005355.txt.gz
PGS002709
(blood_PLATELET_COUNT.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Platelet count platelet count 981,460
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002709/ScoringFiles/PGS002709.txt.gz
PGS002719
(biochemistry_Triglycerides.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Triglycerides triglyceride measurement 981,472
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002719/ScoringFiles/PGS002719.txt.gz
PGS019741
(TPMI_772_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Symptoms of the muscles muscular disease 981,590
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019741/ScoringFiles/PGS019741.txt.gz
PGS019404
(TPMI_577_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Diseases of pancreas pancreas disorder 981,644
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019404/ScoringFiles/PGS019404.txt.gz
PGS002675
(repro_NumberChildrenEverBorn_Pooled.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Number of children ever born number of children ever born measurement 981,889
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002675/ScoringFiles/PGS002675.txt.gz
PGS019686
(TPMI_716.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 981,996
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019686/ScoringFiles/PGS019686.txt.gz
PGS002721
(biochemistry_VitaminD.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Vitamin D vitamin D level 981,998
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002721/ScoringFiles/PGS002721.txt.gz
PGS005136
(forSAS_fromAFR)
PGP000703 |
Tsuo K et al. Cell Genom (2022)
Asthma asthma 982,014
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005136/ScoringFiles/PGS005136.txt.gz
PGS018624
(TPMI_218_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Benign neoplasm of uterus uterine benign neoplasm 982,615
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018624/ScoringFiles/PGS018624.txt.gz
PGS005219
(PRS_BMIadjOSA)
PGP000734 |
Kurniansyah N et al. EBioMedicine (2025)
Obstructive sleep apnea (AdjustedBMI) obstructive sleep apnea syndrome 982,740
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005219/ScoringFiles/PGS005219.txt.gz
PGS019736
(TPMI_764_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Sciatica Sciatica 982,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019736/ScoringFiles/PGS019736.txt.gz
PGS002711
(blood_RED_COUNT.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red blood cell count erythrocyte count 982,902
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002711/ScoringFiles/PGS002711.txt.gz
PGS019055
(TPMI_368_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Visual disturbances Abnormality of vision 983,298
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019055/ScoringFiles/PGS019055.txt.gz
PGS002704
(blood_LYMPHOCYTE_COUNT.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Lymphocyte count lymphocyte count 983,350
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002704/ScoringFiles/PGS002704.txt.gz
PGS018563
(TPMI_185_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Prostate cancer prostate cancer 983,663
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018563/ScoringFiles/PGS018563.txt.gz
PGS019776
(TPMI_796_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Elevated prostate specific antigen PSA prostate specific antigen amount 983,663
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019776/ScoringFiles/PGS019776.txt.gz
PGS002699
(blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
High light scatter reticulocyte count reticulocyte count 983,680
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002699/ScoringFiles/PGS002699.txt.gz
PGS019838
(TPMI_T-BIL_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Total bilirubin bilirubin measurement 983,709
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019838/ScoringFiles/PGS019838.txt.gz
PGS019844
(TPMI_HbA1c_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Glycated hemoglobin HbA1c measurement 983,709
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019844/ScoringFiles/PGS019844.txt.gz
PGS019842
(TPMI_FG_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Fasting glucose glucose measurement 983,717
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019842/ScoringFiles/PGS019842.txt.gz
PGS019060
(TPMI_370_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Keratitis keratitis 983,726
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019060/ScoringFiles/PGS019060.txt.gz
PGS019530
(TPMI_604_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Disorders of penis penile disorder 983,731
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019530/ScoringFiles/PGS019530.txt.gz
PGS019848
(TPMI_HR_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Heart rate heart rate 983,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019848/ScoringFiles/PGS019848.txt.gz
PGS019858
(TPMI_UA_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Uric acid, blood uric acid measurement 983,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019858/ScoringFiles/PGS019858.txt.gz
PGS019845
(TPMI_HCT_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Hematocrit hematocrit 983,735
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019845/ScoringFiles/PGS019845.txt.gz
PGS018809
(TPMI_272.12_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Hyperglyceridemia familial lipoprotein lipase deficiency 983,736
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018809/ScoringFiles/PGS018809.txt.gz
PGS018599
(TPMI_198_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Secondary malignant neoplasm secondary malignant neoplasm 983,738
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018599/ScoringFiles/PGS018599.txt.gz
PGS019846
(TPMI_HDL-C_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
HDL cholesterol LDL cholesterol 983,740
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019846/ScoringFiles/PGS019846.txt.gz
PGS019851
(TPMI_PLT_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Platelet count platelet count 983,740
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019851/ScoringFiles/PGS019851.txt.gz
PGS019323
(TPMI_526.4_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Temporomandibular joint disorders temporomandibular joint disorder 983,748
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019323/ScoringFiles/PGS019323.txt.gz
PGS018533
(TPMI_174.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Breast cancer female breast cancer 983,749
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018533/ScoringFiles/PGS018533.txt.gz
PGS019786
(TPMI_947_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Urticaria urticaria 983,749
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019786/ScoringFiles/PGS019786.txt.gz