Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002269
(PRS47_AMD)
 PGP000299 |
Zekavat SM et al. Ophthalmology (2022)
 Age-related macular degeneration age-related macular degeneration 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002269/ScoringFiles/PGS002269.txt.gz
PGS004606
(AMD-IAMDGC-EUR)
 PGP000582 |
Gorman BR et al. Nat Genet (2024)
 Age-related macular degeneration age-related macular degeneration 1,000,946
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004606/ScoringFiles/PGS004606.txt.gz
PGS004607
(AMD-MVP-AFR)
 PGP000582 |
Gorman BR et al. Nat Genet (2024)
 Age-related macular degeneration age-related macular degeneration 1,067,520
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004607/ScoringFiles/PGS004607.txt.gz
PGS004952
(PRS52_AMD)
 PGP000673 |
Herold JM et al. Invest Ophthalmol Vis Sci (2023)
 Age-related macular degeneration age-related macular degeneration 52
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004952/ScoringFiles/PGS004952.txt.gz
PGS003361
(GSCAN_AgeSmk_2022_PRS_WEIGHTS_AFR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Age of smoking initiation age at initiation of smoking 1,193,754
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003361/ScoringFiles/PGS003361.txt.gz
PGS003362
(GSCAN_AgeSmk_2022_PRS_WEIGHTS_AMR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Age of smoking initiation age at initiation of smoking 1,073,689
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003362/ScoringFiles/PGS003362.txt.gz
PGS003363
(GSCAN_AgeSmk_2022_PRS_WEIGHTS_EAS)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Age of smoking initiation age at initiation of smoking 858,406
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003363/ScoringFiles/PGS003363.txt.gz
PGS003364
(GSCAN_AgeSmk_2022_PRS_WEIGHTS_EUR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Age of smoking initiation age at initiation of smoking 1,055,960
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003364/ScoringFiles/PGS003364.txt.gz
PGS001372
(GBE_INI22146)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age hayfever or allergic rhinitis diagnosed by doctor allergic disease 255
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001372/ScoringFiles/PGS001372.txt.gz
PGS001938
(portability-PLR_log_age_first_sex)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age first had sexual intercourse age at first sexual intercourse measurement 64,164
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001938/ScoringFiles/PGS001938.txt.gz
PGS002156
(portability-ldpred2_log_age_first_sex)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age first had sexual intercourse age at first sexual intercourse measurement 972,919
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002156/ScoringFiles/PGS002156.txt.gz
PGS002215
(portability-ldpred2_no_sex)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age first had sexual intercourse age at first sexual intercourse measurement 633,660
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002215/ScoringFiles/PGS002215.txt.gz
PGS003520
(cont-decay-log_age_first_sex)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Age first had sexual intercourse age at first sexual intercourse measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003520/ScoringFiles/PGS003520.txt.gz
PGS001371
(GBE_INI2976)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age diabetes diagnosed diabetes mellitus,
age at diagnosis		 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001371/ScoringFiles/PGS001371.txt.gz
PGS002820
(ExPRSweb_AgeAtMenopause_ieu-a-1004_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 99,745
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002820/ScoringFiles/PGS002820.txt.gz
PGS002821
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002821/ScoringFiles/PGS002821.txt.gz
PGS002822
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002822/ScoringFiles/PGS002822.txt.gz
PGS002823
(ExPRSweb_AgeAtMenopause_ieu-a-1004_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 1,379,304
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002823/ScoringFiles/PGS002823.txt.gz
PGS002824
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 894,484
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002824/ScoringFiles/PGS002824.txt.gz
PGS002310
(repro_MENARCHE_AGE.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002310/ScoringFiles/PGS002310.txt.gz
PGS002382
(repro_MENARCHE_AGE.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 6,332
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002382/ScoringFiles/PGS002382.txt.gz
PGS002431
(repro_MENARCHE_AGE.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 21,880
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002431/ScoringFiles/PGS002431.txt.gz
PGS002480
(repro_MENARCHE_AGE.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 115,583
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002480/ScoringFiles/PGS002480.txt.gz
PGS002529
(repro_MENARCHE_AGE.P+T.1e-06)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 1,546
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002529/ScoringFiles/PGS002529.txt.gz
PGS002578
(repro_MENARCHE_AGE.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 891
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002578/ScoringFiles/PGS002578.txt.gz
PGS002627
(repro_MENARCHE_AGE.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 831,098
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002627/ScoringFiles/PGS002627.txt.gz
PGS002676
(repro_MENARCHE_AGE.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Age at menarche age at menarche 988,120
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002676/ScoringFiles/PGS002676.txt.gz
PGS002815
(ExPRSweb_AgeAtMenarche_ieu-a-1095_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 137,734
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002815/ScoringFiles/PGS002815.txt.gz
PGS002816
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 13,852
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002816/ScoringFiles/PGS002816.txt.gz
PGS002817
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 13,852
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002817/ScoringFiles/PGS002817.txt.gz
PGS002818
(ExPRSweb_AgeAtMenarche_ieu-a-1095_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 991,712
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002818/ScoringFiles/PGS002818.txt.gz
PGS002819
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 895,562
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002819/ScoringFiles/PGS002819.txt.gz
PGS001007
(GBE_INI2139)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age at first sexual intercourse age at first sexual intercourse measurement 9,997
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001007/ScoringFiles/PGS001007.txt.gz
PGS001912
(portability-PLR_F_age_first_birth)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age at first live birth age at first birth measurement 15,201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001912/ScoringFiles/PGS001912.txt.gz
PGS002127
(portability-ldpred2_F_age_first_birth)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age at first live birth age at first birth measurement 848,784
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002127/ScoringFiles/PGS002127.txt.gz
PGS003505
(cont-decay-F_age_first_birth)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 Age at first live birth age at first birth measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003505/ScoringFiles/PGS003505.txt.gz
PGS001370
(GBE_INI3786)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age asthma diagnosed asthma 922
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001370/ScoringFiles/PGS001370.txt.gz
PGS000758
(LASSO_Height)
 PGP000163 |
Lu T et al. J Clin Endocrinol Metab (2021)
 Adult standing height body height 33,938
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000758/ScoringFiles/PGS000758.txt.gz - Check Terms/Licenses
PGS000717
(PGS557_albs)
 PGP000132 |
Richardson TG et al. BMJ (2020)
 Adult life body size body mass index 557
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000717/ScoringFiles/PGS000717.txt.gz
PGS000034
(GRS_BMI)
 PGP000021 |
Song M et al. Diabetes (2017)
 Adult body mass index (BMI) body mass index 97
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000034/ScoringFiles/PGS000034.txt.gz
PGS000217
(ADM)
 PGP000089 |
Folkersen L et al. Nat Metab (2020)
 Adrenomedullin (ADM) serum levels blood protein amount 552,254
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000217/ScoringFiles/PGS000217.txt.gz
PGS005235
(F4_Adiposity)
 PGP000739 |
Arehart CH et al. Nat Commun (2025)
 Adiposity obesity 709,828
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005235/ScoringFiles/PGS005235.txt.gz
PGS003849
(PRSaddiction-rf)
 PGP000490 |
Hatoum AS et al. Nat Ment Health (2023)
 Addiction risk factors substance-related disorder 584,753
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003849/ScoringFiles/PGS003849.txt.gz
PGS005215
(addiction_rf)
 PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
 Addiction risk factors substance-related disorder 11,627
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005215/ScoringFiles/PGS005215.txt.gz
PGS001314
(GBE_HC938)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Acute myocardial infarction (time-to-event) myocardial infarction 1,108
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001314/ScoringFiles/PGS001314.txt.gz
PGS003448
(PRS15_ALL)
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Acute lymphoblastic leukemia acute lymphoblastic leukemia 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003448/ScoringFiles/PGS003448.txt.gz
PGS001369
(GBE_HC1090)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Acute appendicitis (time-to-event) appendicitis 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001369/ScoringFiles/PGS001369.txt.gz
PGS001785
(1kgeur_gbmi_leaveUKBBout_AcApp_pst_eff_a1_b0.5_phiauto)
 PGP000262 |
Wang Y et al. Cell Genom (2023)
 Acute appendicitis appendicitis 911,334
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001785/ScoringFiles/PGS001785.txt.gz
PGS000914
(PRS6_EC)
 PGP000241 |
Wang M et al. Sci Rep (2021)
 Abnormal electrocardiogram Abnormal EKG 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000914/ScoringFiles/PGS000914.txt.gz
PGS005233
(F2_Abdominal_Size)
 PGP000739 |
Arehart CH et al. Nat Commun (2025)
 Abdominal size body fat distribution 710,487
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005233/ScoringFiles/PGS005233.txt.gz
Showing 5151 to 5200 of 5221 rows