Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000517
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 10
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000517/ScoringFiles/PGS000517.txt.gz
PGS000518
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 10
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000518/ScoringFiles/PGS000518.txt.gz
PGS000553
(PRSWEB_PHECODE184.11_Phelan-LSASBOC_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 10
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000553/ScoringFiles/PGS000553.txt.gz
PGS000630
(PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid carcinoma 10
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000630/ScoringFiles/PGS000630.txt.gz
PGS000631
(PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid carcinoma 10
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000631/ScoringFiles/PGS000631.txt.gz
PGS000642
(PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Non-Hodgkin's lymphoma non-Hodgkins lymphoma 10
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000642/ScoringFiles/PGS000642.txt.gz
PGS000655
(NAFLD-10)
 PGP000119 |
Namjou B et al. BMC Med (2019)
 Non-alcoholic fatty liver disease non-alcoholic fatty liver disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000655/ScoringFiles/PGS000655.txt.gz
PGS000784
(CC_Cervix_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Cervical cancer cervical carcinoma 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000784/ScoringFiles/PGS000784.txt.gz
PGS000867
(GRS10_Allergy)
 PGP000213 |
Arabkhazaeli A et al. Pediatr Allergy Immunol (2017)
 Allergy allergic disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000867/ScoringFiles/PGS000867.txt.gz
PGS001267
(GBE_HC422)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ankylosing spondylitis ankylosing spondylitis 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001267/ScoringFiles/PGS001267.txt.gz
PGS001268
(GBE_HC1242)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ankylosing spondylitis (time-to-event) ankylosing spondylitis 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001268/ScoringFiles/PGS001268.txt.gz
PGS002234
(PRS10_NMR)
 PGP000266 |
Chen LS et al. Pharmacogenomics (2018)
 Nicotine metabolite ratio nicotine metabolite ratio 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002234/ScoringFiles/PGS002234.txt.gz
PGS002290
(GRS10_PUA)
 PGP000318 |
Gurung RL et al. J Clin Endocrinol Metab (2022)
 Uric acid level uric acid measurement 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002290/ScoringFiles/PGS002290.txt.gz
PGS002749
(PRS10_TKR)
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Total knee replacement osteoarthritis, knee,
total knee arthroplasty		 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002749/ScoringFiles/PGS002749.txt.gz
PGS002794
(PRS_VTE)
 PGP000375 |
Xie J et al. J Thromb Haemost (2022)
 Venous thromboembolism venous thromboembolism 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002794/ScoringFiles/PGS002794.txt.gz
PGS003330
(PRS-F8)
 PGP000395 |
Valenti L et al. JHEP Rep (2022)
 Factor VIII levels factor VIII measurement 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003330/ScoringFiles/PGS003330.txt.gz
PGS003404
(wGRS)
 PGP000421 |
Wang J et al. Arterioscler Thromb Vasc Biol (2016)
 LDL cholesterol low density lipoprotein cholesterol measurement 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003404/ScoringFiles/PGS003404.txt.gz
PGS003488
(PRS_IL12)
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 General atopic disease (IL-12 related variants) allergic disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003488/ScoringFiles/PGS003488.txt.gz
PGS003757
(wGRS_SLE_HLA)
 PGP000475 |
Kwon YC et al. Arthritis Rheumatol (2023)
 Systemic lupus erythematosus systemic lupus erythematosus 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003757/ScoringFiles/PGS003757.txt.gz
PGS004286
(GenoBoost_alzheimer_s_disease_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004286/ScoringFiles/PGS004286.txt.gz
PGS000075
(CC_Endo)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Endometrial cancer endometrial carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000075/ScoringFiles/PGS000075.txt.gz
PGS000159
(cGRS_Pancreatic)
 PGP000075 |
Shi Z et al. Cancer Med (2019)
 Pancreatic cancer pancreatic carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000159/ScoringFiles/PGS000159.txt.gz
PGS000192
(GS9)
 PGP000079 |
Kathiresan S et al. N Engl J Med (2008)
 Cholesterol low density lipoprotein cholesterol measurement,
high density lipoprotein cholesterol measurement		 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000192/ScoringFiles/PGS000192.txt.gz
PGS000416
(PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000416/ScoringFiles/PGS000416.txt.gz
PGS000418
(PRSWEB_PHECODE172.1_C43_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000418/ScoringFiles/PGS000418.txt.gz
PGS000468
(PRSWEB_PHECODE172.22_cSCC-Chahal_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000468/ScoringFiles/PGS000468.txt.gz
PGS000521
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000521/ScoringFiles/PGS000521.txt.gz
PGS000595
(PRSWEB_PHECODE187.2_20001-1045_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of testis testicular carcinoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000595/ScoringFiles/PGS000595.txt.gz
PGS000745
(PRS_melanoma_telomere.pathway)
 PGP000151 |
Cust AE et al. J Invest Dermatol (2018)
 Melanoma melanoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000745/ScoringFiles/PGS000745.txt.gz
PGS000776
(GRS9_Cirr)
 PGP000180 |
Innes H et al. Gastroenterology (2020)
 Cirrhosis cirrhosis of liver 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000776/ScoringFiles/PGS000776.txt.gz
PGS000786
(CC_Endo_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Endometrial cancer endometrial carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000786/ScoringFiles/PGS000786.txt.gz
PGS000946
(GBE_HC713)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Unspecified dementia (time-to-event) dementia 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000946/ScoringFiles/PGS000946.txt.gz
PGS001081
(GBE_INI23027)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 JC VP1 antigen for Human Polyomavirus JCV blood protein amount 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001081/ScoringFiles/PGS001081.txt.gz
PGS001300
(GBE_BIN21068)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Celiac disease or gluten sensitivity, diagnosed celiac disease 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001300/ScoringFiles/PGS001300.txt.gz
PGS001385
(GBE_INI21051)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Degree bothered by headaches in the last 3 months health-related quality of life measurement 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001385/ScoringFiles/PGS001385.txt.gz
PGS001515
(GBE_INI3456)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Number of cigarettes currently smoked daily (current cigarette smokers) cigarettes per day measurement 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001515/ScoringFiles/PGS001515.txt.gz
PGS002303
(PRS9_DLBCL)
 PGP000328 |
Choi J et al. Int J Cancer (2020)
 Diffuse large B-cell lymphoma diffuse large B-cell lymphoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002303/ScoringFiles/PGS002303.txt.gz
PGS003025
(ExPRSweb_Hypertension_finngen-R4-I9_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertension 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003025/ScoringFiles/PGS003025.txt.gz
PGS003026
(ExPRSweb_Hypertension_finngen-R4-I9_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertension 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003026/ScoringFiles/PGS003026.txt.gz
PGS003165
(ExPRSweb_VitB12_Wood-et-al-2013-1000G_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin B12 vitamin B12 measurement 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003165/ScoringFiles/PGS003165.txt.gz
PGS003166
(ExPRSweb_VitB12_Wood-et-al-2013-1000G_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin B12 vitamin B12 measurement 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003166/ScoringFiles/PGS003166.txt.gz
PGS005248
(PGS4_QBB_9SNP)
 PGP000743 |
Ismail Umlai UK et al. J Lipid Res (2025)
 LDL-C levels low density lipoprotein cholesterol measurement 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005248/ScoringFiles/PGS005248.txt.gz
PGS000450
(PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000450/ScoringFiles/PGS000450.txt.gz
PGS000543
(PRSWEB_PHECODE184_C3-FEMALE-GENITAL_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Cancer of other female genital organs female reproductive system neoplasm 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000543/ScoringFiles/PGS000543.txt.gz
PGS000626
(PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000626/ScoringFiles/PGS000626.txt.gz
PGS000629
(PRSWEB_PHECODE193_C73_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000629/ScoringFiles/PGS000629.txt.gz
PGS000632
(PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000632/ScoringFiles/PGS000632.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS002245
(PGS8_LF)
 PGP000273 |
Haas ME et al. Cell Genom (2021)
 Liver fat (MRI-derived) liver fat measurement 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002245/ScoringFiles/PGS002245.txt.gz
PGS002277
(pPS_Insulin_secretion_1)
 PGP000305 |
Siddiqui MK et al. Diabetologia (2022)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz
Showing 5151 to 5200 of 5296 rows