Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002794
(PRS_VTE)
 PGP000375 |
Xie J et al. J Thromb Haemost (2022)
 Venous thromboembolism venous thromboembolism 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002794/ScoringFiles/PGS002794.txt.gz
PGS003330
(PRS-F8)
 PGP000395 |
Valenti L et al. JHEP Rep (2022)
 Factor VIII levels factor VIII measurement 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003330/ScoringFiles/PGS003330.txt.gz
PGS003404
(wGRS)
 PGP000421 |
Wang J et al. Arterioscler Thromb Vasc Biol (2016)
 LDL cholesterol low density lipoprotein cholesterol measurement 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003404/ScoringFiles/PGS003404.txt.gz
PGS003488
(PRS_IL12)
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 General atopic disease (IL-12 related variants) allergic disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003488/ScoringFiles/PGS003488.txt.gz
PGS003757
(wGRS_SLE_HLA)
 PGP000475 |
Kwon YC et al. Arthritis Rheumatol (2023)
 Systemic lupus erythematosus systemic lupus erythematosus 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003757/ScoringFiles/PGS003757.txt.gz
PGS004286
(GenoBoost_alzheimer_s_disease_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004286/ScoringFiles/PGS004286.txt.gz
PGS012549
(PRS10_NAFLD)
 PGP000792 |
Tang L et al. BMC Med (2023)
 Nonalcoholic fatty liver disease metabolic dysfunction-associated steatotic liver disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012549/ScoringFiles/PGS012549.txt.gz
PGS000075
(CC_Endo)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Endometrial cancer endometrial carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000075/ScoringFiles/PGS000075.txt.gz
PGS000159
(cGRS_Pancreatic)
 PGP000075 |
Shi Z et al. Cancer Med (2019)
 Pancreatic cancer exocrine pancreatic carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000159/ScoringFiles/PGS000159.txt.gz
PGS000192
(GS9)
 PGP000079 |
Kathiresan S et al. N Engl J Med (2008)
 Cholesterol low density lipoprotein cholesterol measurement,
high density lipoprotein cholesterol measurement		 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000192/ScoringFiles/PGS000192.txt.gz
PGS000416
(PRSWEB_PHECODE172.1_C43_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000416/ScoringFiles/PGS000416.txt.gz
PGS000418
(PRSWEB_PHECODE172.1_C43_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000418/ScoringFiles/PGS000418.txt.gz
PGS000468
(PRSWEB_PHECODE172.22_cSCC-Chahal_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000468/ScoringFiles/PGS000468.txt.gz
PGS000521
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000521/ScoringFiles/PGS000521.txt.gz
PGS000595
(PRSWEB_PHECODE187.2_20001-1045_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of testis testicular cancer 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000595/ScoringFiles/PGS000595.txt.gz
PGS000745
(PRS_melanoma_telomere.pathway)
 PGP000151 |
Cust AE et al. J Invest Dermatol (2018)
 Melanoma melanoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000745/ScoringFiles/PGS000745.txt.gz
PGS000776
(GRS9_Cirr)
 PGP000180 |
Innes H et al. Gastroenterology (2020)
 Cirrhosis cirrhosis of liver 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000776/ScoringFiles/PGS000776.txt.gz
PGS000786
(CC_Endo_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Endometrial cancer endometrial carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000786/ScoringFiles/PGS000786.txt.gz
PGS000946
(GBE_HC713)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Unspecified dementia (time-to-event) dementia 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000946/ScoringFiles/PGS000946.txt.gz
PGS001081
(GBE_INI23027)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 JC VP1 antigen for Human Polyomavirus JCV blood protein amount 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001081/ScoringFiles/PGS001081.txt.gz
PGS001300
(GBE_BIN21068)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Celiac disease or gluten sensitivity, diagnosed celiac disease 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001300/ScoringFiles/PGS001300.txt.gz
PGS001385
(GBE_INI21051)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Degree bothered by headaches in the last 3 months health-related quality of life measurement 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001385/ScoringFiles/PGS001385.txt.gz
PGS001515
(GBE_INI3456)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Number of cigarettes currently smoked daily (current cigarette smokers) cigarettes per day measurement 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001515/ScoringFiles/PGS001515.txt.gz
PGS002303
(PRS9_DLBCL)
 PGP000328 |
Choi J et al. Int J Cancer (2020)
 Diffuse large B-cell lymphoma diffuse large B-cell lymphoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002303/ScoringFiles/PGS002303.txt.gz
PGS003025
(ExPRSweb_Hypertension_finngen-R4-I9_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003025/ScoringFiles/PGS003025.txt.gz
PGS003026
(ExPRSweb_Hypertension_finngen-R4-I9_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003026/ScoringFiles/PGS003026.txt.gz
PGS003165
(ExPRSweb_VitB12_Wood-et-al-2013-1000G_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin B12 vitamin B12 measurement 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003165/ScoringFiles/PGS003165.txt.gz
PGS003166
(ExPRSweb_VitB12_Wood-et-al-2013-1000G_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin B12 vitamin B12 measurement 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003166/ScoringFiles/PGS003166.txt.gz
PGS005248
(PGS4_QBB_9SNP)
 PGP000743 |
Ismail Umlai UK et al. J Lipid Res (2025)
 LDL-C levels low density lipoprotein cholesterol measurement 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005248/ScoringFiles/PGS005248.txt.gz
PGS000450
(PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000450/ScoringFiles/PGS000450.txt.gz
PGS000543
(PRSWEB_PHECODE184_C3-FEMALE-GENITAL_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Cancer of other female genital organs female reproductive system neoplasm 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000543/ScoringFiles/PGS000543.txt.gz
PGS000626
(PRSWEB_PHECODE193_20001-1065_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid gland carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000626/ScoringFiles/PGS000626.txt.gz
PGS000629
(PRSWEB_PHECODE193_C73_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid gland carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000629/ScoringFiles/PGS000629.txt.gz
PGS000632
(PRSWEB_PHECODE193_GWAS-Catalog-r2019-05-03-X193_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid gland carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000632/ScoringFiles/PGS000632.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS002245
(PGS8_LF)
 PGP000273 |
Haas ME et al. Cell Genom (2021)
 Liver fat (MRI-derived) liver fat measurement 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002245/ScoringFiles/PGS002245.txt.gz
PGS002277
(pPS_Insulin_secretion_1)
 PGP000305 |
Siddiqui MK et al. Diabetologia (2022)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz
PGS003442
(GRS8_MD)
 PGP000444 |
Petrican R et al. Sci Rep (2023)
 Major depressive disorder major depressive disorder 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003442/ScoringFiles/PGS003442.txt.gz
PGS003613
(L_CA1_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA1 body volume hippocampal CA1 volume 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003613/ScoringFiles/PGS003613.txt.gz
PGS004221
(PRS8_carbohydrate)
 PGP000521 |
Merino J et al. Mol Psychiatry (2023)
 Carbohydrate preference carbohydrate intake measurement 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004221/ScoringFiles/PGS004221.txt.gz
PGS004909
(EUR_wGRS7)
 PGP000641 |
El-Boraie A et al. Addict Biol (2019)
 Nicotine metabolite ratio nicotine metabolite ratio 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004909/ScoringFiles/PGS004909.txt.gz
PGS004918
(PRS8_Synapse)
 PGP000649 |
Lawingco T et al. Neurobiol Aging (2020)
 Late-onset Alzheimers disease (based on SNPs in genes involved in synaptic function) late-onset Alzheimer's disease 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004918/ScoringFiles/PGS004918.txt.gz
PGS012562
(PRS8_PU)
 PGP000802 |
Li J et al. Environ Res (2024)
 Peptic ulcer disease peptic ulcer disease 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012562/ScoringFiles/PGS012562.txt.gz
PGS000023
(AA_GRS)
 PGP000013 |
Onengut-Gumuscu S et al. Diabetes Care (2019)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000023/ScoringFiles/PGS000023.txt.gz
PGS000315
(GRS7_lgE)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Immunoglobulin E (IgE) serum IgE amount 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000315/ScoringFiles/PGS000315.txt.gz
PGS000410
(PRSWEB_PHECODE172.1_20001-1059_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000410/ScoringFiles/PGS000410.txt.gz
PGS000463
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000463/ScoringFiles/PGS000463.txt.gz
PGS000471
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Carcinoma in situ of skin skin carcinoma in situ 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000471/ScoringFiles/PGS000471.txt.gz
PGS000664
(GRS7_GFR)
 PGP000124 |
Gorski M et al. Kidney Int (2020)
 Rapid decline of glomerular filtration rate (GFR) GFR change measurement 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000664/ScoringFiles/PGS000664.txt.gz
PGS000779
(PGS7_AD)
 PGP000183 |
Zhou X et al. Alzheimers Dement (Amst) (2020)
 Alzheimer's disease Alzheimer disease 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000779/ScoringFiles/PGS000779.txt.gz
Showing 5251 to 5300 of 5385 rows