Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019141
(TPMI_401.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart and or renal disease hypertensive heart disease 983,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019141/ScoringFiles/PGS019141.txt.gz
PGS019854
(TPMI_SBP_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Systolic blood pressure systolic blood pressure 983,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019854/ScoringFiles/PGS019854.txt.gz
PGS018847
(TPMI_278_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Overweight obesity and other hyperalimentation obesity disorder 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018847/ScoringFiles/PGS018847.txt.gz
PGS018959
(TPMI_317_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcohol related disorders alcohol-related disorders 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018959/ScoringFiles/PGS018959.txt.gz
PGS019348
(TPMI_550.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Inguinal hernia Inguinal hernia 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019348/ScoringFiles/PGS019348.txt.gz
PGS019358
(TPMI_571_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic liver disease and cirrhosis alcoholic liver cirrhosis 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019358/ScoringFiles/PGS019358.txt.gz
PGS019440
(TPMI_585.32_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 End stage renal disease stage 5 chronic kidney disease 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019440/ScoringFiles/PGS019440.txt.gz
PGS019850
(TPMI_MAP_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mean arterial pressure mean arterial pressure 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019850/ScoringFiles/PGS019850.txt.gz
PGS019852
(TPMI_PP_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Pulse pressure pulse pressure measurement 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019852/ScoringFiles/PGS019852.txt.gz
PGS018819
(TPMI_274_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Gout and other crystal arthropathies chondrocalcinosis 2 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018819/ScoringFiles/PGS018819.txt.gz
PGS018825
(TPMI_274.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Gout gout 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018825/ScoringFiles/PGS018825.txt.gz
PGS018934
(TPMI_292.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mild cognitive impairment Cognitive impairment 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018934/ScoringFiles/PGS018934.txt.gz
PGS019129
(TPMI_401_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertension Hypertension 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019129/ScoringFiles/PGS019129.txt.gz
PGS019418
(TPMI_580.31_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Nephritis and nephropathy in diseases classified elsewhere Nephropathy,
nephritis		 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019418/ScoringFiles/PGS019418.txt.gz
PGS019837
(TPMI_ALT_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Serum glutamate pyruvate transaminase serum alanine aminotransferase amount 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019837/ScoringFiles/PGS019837.txt.gz
PGS019841
(TPMI_DBP_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diastolic blood pressure diastolic blood pressure 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019841/ScoringFiles/PGS019841.txt.gz
PGS019700
(TPMI_723_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of cervical region cervical neck region 983,788
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019700/ScoringFiles/PGS019700.txt.gz
PGS018518
(TPMI_165_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Respiratory system cancer respiratory system cancer 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018518/ScoringFiles/PGS018518.txt.gz
PGS018523
(TPMI_165.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of bronchus lung bronchus cancer 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018523/ScoringFiles/PGS018523.txt.gz
PGS018779
(TPMI_250.41_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Impaired fasting glucose Impaired glucose tolerance 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018779/ScoringFiles/PGS018779.txt.gz
PGS018804
(TPMI_272.11_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypercholesterolemia Hypercholesterolemia 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018804/ScoringFiles/PGS018804.txt.gz
PGS018919
(TPMI_291_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other specified nonpsychotic and or transient mental disorders mental disorder 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018919/ScoringFiles/PGS018919.txt.gz
PGS019152
(TPMI_401.21_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019152/ScoringFiles/PGS019152.txt.gz
PGS019510
(TPMI_598.9_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other nonspecific findings on examination of urine abnormal result of function studies 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019510/ScoringFiles/PGS019510.txt.gz
PGS019771
(TPMI_795.8_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal tumor markers cancer biomarker measurement 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019771/ScoringFiles/PGS019771.txt.gz
PGS018814
(TPMI_272.13_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mixed hyperlipidemia hyperlipidemia 983,790
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018814/ScoringFiles/PGS018814.txt.gz
PGS019705
(TPMI_724_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other and unspecified disorders of back Abnormality of the vertebral column 983,790
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019705/ScoringFiles/PGS019705.txt.gz
PGS018904
(TPMI_290.3_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 983,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018904/ScoringFiles/PGS018904.txt.gz
PGS018914
(TPMI_290.13_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Senile dementia dementia 983,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018914/ScoringFiles/PGS018914.txt.gz
PGS019766
(TPMI_795_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other and nonspecific abnormal cytological histological and immunological findings cytological, histological or immunological finding 983,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019766/ScoringFiles/PGS019766.txt.gz
PGS018478
(TPMI_150_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Esophageal cancer esophageal cancer 983,792
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018478/ScoringFiles/PGS018478.txt.gz
PGS019308
(TPMI_523.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Gingivitis gingivitis 983,793
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019308/ScoringFiles/PGS019308.txt.gz
PGS019413
(TPMI_580.3_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Nephritis and nephropathy without mention of glomerulonephritis Nephropathy 983,793
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019413/ScoringFiles/PGS019413.txt.gz
PGS019839
(TPMI_BMI_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Body mass index (BMI) body mass index 983,794
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019839/ScoringFiles/PGS019839.txt.gz
PGS019720
(TPMI_729.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Rheumatism unspecified and fibrositis rheumatic disorder 983,795
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019720/ScoringFiles/PGS019720.txt.gz
PGS018732
(TPMI_250.4_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal glucose Abnormal blood glucose concentration 983,796
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018732/ScoringFiles/PGS018732.txt.gz
PGS018799
(TPMI_272.9_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Unspecified disorder of lipoid metabolism inherited lipid metabolism disorder 983,798
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018799/ScoringFiles/PGS018799.txt.gz
PGS019059
(TPMI_370_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Keratitis keratitis 983,798
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019059/ScoringFiles/PGS019059.txt.gz
PGS018488
(TPMI_153_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Colorectal cancer colorectal cancer 983,800
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018488/ScoringFiles/PGS018488.txt.gz
PGS019847
(TPMI_HT_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Body height body height 983,800
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019847/ScoringFiles/PGS019847.txt.gz
PGS019710
(TPMI_728_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Disorders of muscle ligament and fascia soft tissue disease 983,801
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019710/ScoringFiles/PGS019710.txt.gz
PGS018493
(TPMI_153.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Colon cancer malignant colon neoplasm 983,802
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018493/ScoringFiles/PGS018493.txt.gz
PGS019024
(TPMI_362.6_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Peripheral retinal degenerations retinal degeneration 983,802
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019024/ScoringFiles/PGS019024.txt.gz
PGS019273
(TPMI_475_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic sinusitis chronic rhinosinusitis 983,804
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019273/ScoringFiles/PGS019273.txt.gz
PGS019715
(TPMI_728.7_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fasciitis Fasciitis 983,805
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019715/ScoringFiles/PGS019715.txt.gz
PGS018939
(TPMI_296.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Depression depressive disorder 983,806
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018939/ScoringFiles/PGS018939.txt.gz
PGS018949
(TPMI_306_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other mental disorder mental disorder 983,807
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018949/ScoringFiles/PGS018949.txt.gz
PGS018438
(TPMI_070.9_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hepatitis NOS Hepatitis 983,808
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018438/ScoringFiles/PGS018438.txt.gz
PGS018944
(TPMI_300.11_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Generalized anxiety disorder generalized anxiety disorder 983,808
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018944/ScoringFiles/PGS018944.txt.gz
PGS019147
(TPMI_401.3_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other hypertensive complications hypertensive disorder 983,809
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019147/ScoringFiles/PGS019147.txt.gz
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