Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS018948
(TPMI_306_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other mental disorder mental disorder 22,265
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018948/ScoringFiles/PGS018948.txt.gz
PGS018949
(TPMI_306_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other mental disorder mental disorder 983,807
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018949/ScoringFiles/PGS018949.txt.gz
PGS018950
(TPMI_306_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other mental disorder mental disorder 922,093
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018950/ScoringFiles/PGS018950.txt.gz
PGS018951
(TPMI_315_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Develomental delays and disorders specific developmental disorder 21
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018951/ScoringFiles/PGS018951.txt.gz
PGS018952
(TPMI_315_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Develomental delays and disorders specific developmental disorder 178,694
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018952/ScoringFiles/PGS018952.txt.gz
PGS018953
(TPMI_315_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Develomental delays and disorders specific developmental disorder 28,656
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018953/ScoringFiles/PGS018953.txt.gz
PGS018954
(TPMI_315_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Develomental delays and disorders specific developmental disorder 983,831
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018954/ScoringFiles/PGS018954.txt.gz
PGS018955
(TPMI_315_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Develomental delays and disorders specific developmental disorder 1,013,967
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018955/ScoringFiles/PGS018955.txt.gz
PGS018956
(TPMI_317_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcohol related disorders alcohol-related disorders 30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018956/ScoringFiles/PGS018956.txt.gz
PGS018957
(TPMI_317_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcohol related disorders alcohol-related disorders 939,840
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018957/ScoringFiles/PGS018957.txt.gz
PGS018958
(TPMI_317_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcohol related disorders alcohol-related disorders 22,608
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018958/ScoringFiles/PGS018958.txt.gz
PGS018959
(TPMI_317_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcohol related disorders alcohol-related disorders 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018959/ScoringFiles/PGS018959.txt.gz
PGS018960
(TPMI_317_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcohol related disorders alcohol-related disorders 913,261
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018960/ScoringFiles/PGS018960.txt.gz
PGS018961
(TPMI_317.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcoholism alcohol dependence 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018961/ScoringFiles/PGS018961.txt.gz
PGS018962
(TPMI_317.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcoholism alcohol dependence 939,838
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018962/ScoringFiles/PGS018962.txt.gz
PGS018963
(TPMI_317.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcoholism alcohol dependence 25,361
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018963/ScoringFiles/PGS018963.txt.gz
PGS018964
(TPMI_317.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcoholism alcohol dependence 983,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018964/ScoringFiles/PGS018964.txt.gz
PGS018965
(TPMI_317.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alcoholism alcohol dependence 1,013,582
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018965/ScoringFiles/PGS018965.txt.gz
PGS018966
(TPMI_327.5_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Parasomnia Parasomnia 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018966/ScoringFiles/PGS018966.txt.gz
PGS018967
(TPMI_327.5_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Parasomnia Parasomnia 939,819
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018967/ScoringFiles/PGS018967.txt.gz
PGS018968
(TPMI_327.5_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Parasomnia Parasomnia 516,575
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018968/ScoringFiles/PGS018968.txt.gz
PGS018969
(TPMI_327.5_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Parasomnia Parasomnia 983,781
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018969/ScoringFiles/PGS018969.txt.gz
PGS018970
(TPMI_327.5_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Parasomnia Parasomnia 1,011,580
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018970/ScoringFiles/PGS018970.txt.gz
PGS018971
(TPMI_327.7_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Sleep related movement disorders movement disorder 147,703
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018971/ScoringFiles/PGS018971.txt.gz
PGS018972
(TPMI_327.7_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Sleep related movement disorders movement disorder 939,812
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018972/ScoringFiles/PGS018972.txt.gz
PGS018973
(TPMI_327.7_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Sleep related movement disorders movement disorder 10,770
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018973/ScoringFiles/PGS018973.txt.gz
PGS018974
(TPMI_327.7_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Sleep related movement disorders movement disorder 983,773
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018974/ScoringFiles/PGS018974.txt.gz
PGS018975
(TPMI_327.7_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Sleep related movement disorders movement disorder 1,002,797
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018975/ScoringFiles/PGS018975.txt.gz
PGS018976
(TPMI_327.41_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Organic or persistent insomnia insomnia 246,776
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018976/ScoringFiles/PGS018976.txt.gz
PGS018977
(TPMI_327.41_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Organic or persistent insomnia insomnia 939,879
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018977/ScoringFiles/PGS018977.txt.gz
PGS018978
(TPMI_327.41_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Organic or persistent insomnia insomnia 23,384
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018978/ScoringFiles/PGS018978.txt.gz
PGS018979
(TPMI_327.41_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Organic or persistent insomnia insomnia 983,818
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018979/ScoringFiles/PGS018979.txt.gz
PGS018980
(TPMI_327.41_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Organic or persistent insomnia insomnia 967,358
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018980/ScoringFiles/PGS018980.txt.gz
PGS018981
(TPMI_331_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other cerebral degenerations Cerebral degeneration 9,219
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018981/ScoringFiles/PGS018981.txt.gz
PGS018982
(TPMI_331_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other cerebral degenerations Cerebral degeneration 256,810
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018982/ScoringFiles/PGS018982.txt.gz
PGS018983
(TPMI_331_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other cerebral degenerations Cerebral degeneration 15,782
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018983/ScoringFiles/PGS018983.txt.gz
PGS018984
(TPMI_331_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other cerebral degenerations Cerebral degeneration 983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018984/ScoringFiles/PGS018984.txt.gz
PGS018985
(TPMI_331_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other cerebral degenerations Cerebral degeneration 796,395
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018985/ScoringFiles/PGS018985.txt.gz
PGS018986
(TPMI_340_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Migraine migraine disorder 154,713
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018986/ScoringFiles/PGS018986.txt.gz
PGS018987
(TPMI_340_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Migraine migraine disorder 356,947
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018987/ScoringFiles/PGS018987.txt.gz
PGS018988
(TPMI_340_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Migraine migraine disorder 19,422
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018988/ScoringFiles/PGS018988.txt.gz
PGS018989
(TPMI_340_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Migraine migraine disorder 983,774
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018989/ScoringFiles/PGS018989.txt.gz
PGS018990
(TPMI_340_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Migraine migraine disorder 959,731
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018990/ScoringFiles/PGS018990.txt.gz
PGS018991
(TPMI_345.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Epilepsy epilepsy 65
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018991/ScoringFiles/PGS018991.txt.gz
PGS018992
(TPMI_345.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Epilepsy epilepsy 300,225
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018992/ScoringFiles/PGS018992.txt.gz
PGS018993
(TPMI_345.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Epilepsy epilepsy 16,624
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018993/ScoringFiles/PGS018993.txt.gz
PGS018994
(TPMI_345.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Epilepsy epilepsy 983,823
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018994/ScoringFiles/PGS018994.txt.gz
PGS018995
(TPMI_345.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Epilepsy epilepsy 997,881
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018995/ScoringFiles/PGS018995.txt.gz
PGS018996
(TPMI_352.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Facial nerve disorders CN7 facial nerve disorder 241,782
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018996/ScoringFiles/PGS018996.txt.gz
PGS018997
(TPMI_352.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Facial nerve disorders CN7 facial nerve disorder 939,882
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018997/ScoringFiles/PGS018997.txt.gz
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