Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004620
(PGS_weights_BBJ2nd_LowBMI_of_2groups)
 PGP000593 |
Ojima T et al. Nat Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 728,824
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004620/ScoringFiles/PGS004620.txt.gz
PGS004837
(t2d_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 3,306,136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004837/ScoringFiles/PGS004837.txt.gz
PGS004838
(t2d_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004838/ScoringFiles/PGS004838.txt.gz
PGS004839
(t2d_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 4,594,694
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004839/ScoringFiles/PGS004839.txt.gz
PGS004840
(t2d_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004840/ScoringFiles/PGS004840.txt.gz
PGS004859
(T2D_PRS_CS)
 PGP000605 |
Deutsch AJ et al. Diabetes Care (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,108,235
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004859/ScoringFiles/PGS004859.txt.gz
PGS004868
(T2DPGS)
 PGP000617 |
Yun JS et al. Cardiovasc Diabetol (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,580,804
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004868/ScoringFiles/PGS004868.txt.gz
PGS004870
(INTERVENE_MegaPRS_T2D)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 930,506
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004870/ScoringFiles/PGS004870.txt.gz
PGS004887
(T2D_gePGS)
 PGP000619 |
Mandla R et al. Genome Med (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,117,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004887/ScoringFiles/PGS004887.txt.gz
PGS004923
(T2D_metaGRS)
 PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,349,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004923/ScoringFiles/PGS004923.txt.gz
PGS005108
(PRSdiabetes)
 PGP000697 |
Takase M et al. J Atheroscler Thromb (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 42,845
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005108/ScoringFiles/PGS005108.txt.gz
PGS005110
(PGS_T2D_gw)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,114,950
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005110/ScoringFiles/PGS005110.txt.gz
PGS005111
(PGS_T2D_gwas)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 150
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005111/ScoringFiles/PGS005111.txt.gz
PGS005115
(PGS_T2D_beta_cell)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 30
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005115/ScoringFiles/PGS005115.txt.gz
PGS005116
(PGS_T2D_lipodystrophy)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 20
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005116/ScoringFiles/PGS005116.txt.gz
PGS005117
(PGS_T2D_liver_lipid)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 5
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005117/ScoringFiles/PGS005117.txt.gz
PGS005118
(PGS_T2D_obesity)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 5
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005118/ScoringFiles/PGS005118.txt.gz
PGS005119
(PGS_T2D_proinsulin)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 7
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005119/ScoringFiles/PGS005119.txt.gz
PGS005147
(Type 2 diabetes (PRS-CS; EAS))
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 908,465
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005147/ScoringFiles/PGS005147.txt.gz
PGS005157
(Type 2 diabetes (CT-SLEB; EAS+EUR))
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 502,115
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005157/ScoringFiles/PGS005157.txt.gz
PGS005242
(T2D_PRS_PRS_CSx_META_T)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,036
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005242/ScoringFiles/PGS005242.txt.gz
PGS005243
(T2D_PRS_PRS_CSx_META_F_AFR)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,183,017
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005243/ScoringFiles/PGS005243.txt.gz
PGS005244
(T2D_PRS_PRS_CSx_META_F_AMR)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 960,470
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005244/ScoringFiles/PGS005244.txt.gz
PGS005245
(T2D_PRS_PRS_CSx_META_F_EAS)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,021,829
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005245/ScoringFiles/PGS005245.txt.gz
PGS005246
(T2D_PRS_PRS_CSx_META_F_EUR)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,111,848
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005246/ScoringFiles/PGS005246.txt.gz
PGS005247
(T2D_PRS_PRS_CSx_META_F_SAS)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,126,657
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005247/ScoringFiles/PGS005247.txt.gz
PGS005314
(T2D_PRS_AA)
 PGP000762 |
Irvin MR et al. Diabetes (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,181,614
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005314/ScoringFiles/PGS005314.txt.gz
PGS005324
(T2D_PRS_weighted)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,279,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005324/ScoringFiles/PGS005324.txt.gz
PGS005325
(T2D_PRS_unweighted)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,279,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005325/ScoringFiles/PGS005325.txt.gz
PGS005326
(T2D_PRS_AFR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,214,634
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005326/ScoringFiles/PGS005326.txt.gz
PGS005327
(T2D_PRS_AMR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 972,776
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005327/ScoringFiles/PGS005327.txt.gz
PGS005328
(T2D_PRS_EAS)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 570,349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005328/ScoringFiles/PGS005328.txt.gz
PGS005329
(T2D_PRS_EUR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,112,468
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005329/ScoringFiles/PGS005329.txt.gz
PGS005330
(T2D_PRS_SAS)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 642,349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005330/ScoringFiles/PGS005330.txt.gz
PGS000032
(GRSB)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (based on SNPs involved in β-cell function) type 2 diabetes mellitus 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000032/ScoringFiles/PGS000032.txt.gz
PGS000033
(GRSIR)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (based on SNPs involved in insulin resistance) type 2 diabetes mellitus 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000033/ScoringFiles/PGS000033.txt.gz
PGS000858
(T2D_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with proinsulin levels) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz
PGS000857
(T2D_Obesity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with obesity) type 2 diabetes mellitus 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000857/ScoringFiles/PGS000857.txt.gz
PGS000856
(T2D_LiverLipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with liver lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000856/ScoringFiles/PGS000856.txt.gz
PGS000855
(T2D_Lipodystrophy)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with lipodystrophy) type 2 diabetes mellitus 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS000853
(T2D_Insulin_Secretion_2)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz
PGS002277
(pPS_Insulin_secretion_1)
 PGP000305 |
Siddiqui MK et al. Diabetologia (2022)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS000850
(T2D_Insulin_Action)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000849
(T2D_Impaired_Lipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with impaired lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000849/ScoringFiles/PGS000849.txt.gz
PGS000854
(T2D_BetaCell)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS000848
(T2D_Adiposity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with adiposity) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz
PGS004181
(t2d_1)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Type 2 diabetes type 2 diabetes mellitus 10,202
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004181/ScoringFiles/PGS004181.txt.gz
PGS004182
(t2d_2)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Type 2 diabetes type 2 diabetes mellitus 10,778
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004182/ScoringFiles/PGS004182.txt.gz
Showing 601 to 650 of 5198 rows