Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019148
(TPMI_401.3_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other hypertensive complications hypertensive disorder 442,448
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019148/ScoringFiles/PGS019148.txt.gz
PGS019149
(TPMI_401.21_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 69,926
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019149/ScoringFiles/PGS019149.txt.gz
PGS019150
(TPMI_401.21_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 939,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019150/ScoringFiles/PGS019150.txt.gz
PGS019151
(TPMI_401.21_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 86,725
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019151/ScoringFiles/PGS019151.txt.gz
PGS019152
(TPMI_401.21_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019152/ScoringFiles/PGS019152.txt.gz
PGS019153
(TPMI_401.21_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 1,071,463
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019153/ScoringFiles/PGS019153.txt.gz
PGS019154
(TPMI_401.21_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 1,001,869
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019154/ScoringFiles/PGS019154.txt.gz
PGS019155
(TPMI_411_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Ischemic Heart Disease myocardial ischemia 34,377
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019155/ScoringFiles/PGS019155.txt.gz
PGS019156
(TPMI_411_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Ischemic Heart Disease myocardial ischemia 939,890
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019156/ScoringFiles/PGS019156.txt.gz
PGS019157
(TPMI_411_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Ischemic Heart Disease myocardial ischemia 39,211
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019157/ScoringFiles/PGS019157.txt.gz
PGS019158
(TPMI_411_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Ischemic Heart Disease myocardial ischemia 983,824
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019158/ScoringFiles/PGS019158.txt.gz
PGS019159
(TPMI_411_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Ischemic Heart Disease myocardial ischemia 931,264
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019159/ScoringFiles/PGS019159.txt.gz
PGS019160
(TPMI_411.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Myocardial infarction myocardial infarction 162,159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019160/ScoringFiles/PGS019160.txt.gz
PGS019161
(TPMI_411.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Myocardial infarction myocardial infarction 394,972
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019161/ScoringFiles/PGS019161.txt.gz
PGS019162
(TPMI_411.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Myocardial infarction myocardial infarction 684,078
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019162/ScoringFiles/PGS019162.txt.gz
PGS019163
(TPMI_411.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Myocardial infarction myocardial infarction 983,764
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019163/ScoringFiles/PGS019163.txt.gz
PGS019164
(TPMI_411.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Myocardial infarction myocardial infarction 1,031,953
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019164/ScoringFiles/PGS019164.txt.gz
PGS019165
(TPMI_411.4_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 18,489
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019165/ScoringFiles/PGS019165.txt.gz
PGS019166
(TPMI_411.4_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 939,870
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019166/ScoringFiles/PGS019166.txt.gz
PGS019167
(TPMI_411.4_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 31,979
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019167/ScoringFiles/PGS019167.txt.gz
PGS019168
(TPMI_411.4_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 983,811
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019168/ScoringFiles/PGS019168.txt.gz
PGS019169
(TPMI_411.4_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 941,902
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019169/ScoringFiles/PGS019169.txt.gz
PGS019170
(TPMI_411.8_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other chronic ischemic heart disease unspecified chronic pulmonary heart disease 36,363
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019170/ScoringFiles/PGS019170.txt.gz
PGS019171
(TPMI_411.8_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other chronic ischemic heart disease unspecified chronic pulmonary heart disease 939,887
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019171/ScoringFiles/PGS019171.txt.gz
PGS019172
(TPMI_411.8_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other chronic ischemic heart disease unspecified chronic pulmonary heart disease 36,574
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019172/ScoringFiles/PGS019172.txt.gz
PGS019173
(TPMI_411.8_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other chronic ischemic heart disease unspecified chronic pulmonary heart disease 983,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019173/ScoringFiles/PGS019173.txt.gz
PGS019174
(TPMI_411.8_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other chronic ischemic heart disease unspecified chronic pulmonary heart disease 935,962
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019174/ScoringFiles/PGS019174.txt.gz
PGS019175
(TPMI_414_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other forms of chronic heart disease chronic pulmonary heart disease 583,608
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019175/ScoringFiles/PGS019175.txt.gz
PGS019176
(TPMI_414_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other forms of chronic heart disease chronic pulmonary heart disease 939,813
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019176/ScoringFiles/PGS019176.txt.gz
PGS019177
(TPMI_414_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other forms of chronic heart disease chronic pulmonary heart disease 189,507
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019177/ScoringFiles/PGS019177.txt.gz
PGS019178
(TPMI_414_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other forms of chronic heart disease chronic pulmonary heart disease 983,765
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019178/ScoringFiles/PGS019178.txt.gz
PGS019179
(TPMI_414_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other forms of chronic heart disease chronic pulmonary heart disease 1,024,278
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019179/ScoringFiles/PGS019179.txt.gz
PGS019180
(TPMI_414.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 ASCVD cardiovascular disorder 72
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019180/ScoringFiles/PGS019180.txt.gz
PGS019181
(TPMI_414.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 ASCVD cardiovascular disorder 363,229
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019181/ScoringFiles/PGS019181.txt.gz
PGS019182
(TPMI_414.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 ASCVD cardiovascular disorder 170,713
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019182/ScoringFiles/PGS019182.txt.gz
PGS019183
(TPMI_414.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 ASCVD cardiovascular disorder 983,768
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019183/ScoringFiles/PGS019183.txt.gz
PGS019184
(TPMI_414.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 ASCVD cardiovascular disorder 1,022,962
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019184/ScoringFiles/PGS019184.txt.gz
PGS019185
(TPMI_427_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cardiac dysrhythmias cardiac arrhythmia 2,731
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019185/ScoringFiles/PGS019185.txt.gz
PGS019186
(TPMI_427_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cardiac dysrhythmias cardiac arrhythmia 939,890
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019186/ScoringFiles/PGS019186.txt.gz
PGS019187
(TPMI_427_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cardiac dysrhythmias cardiac arrhythmia 38,526
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019187/ScoringFiles/PGS019187.txt.gz
PGS019188
(TPMI_427_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cardiac dysrhythmias cardiac arrhythmia 983,828
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019188/ScoringFiles/PGS019188.txt.gz
PGS019189
(TPMI_427_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cardiac dysrhythmias cardiac arrhythmia 144,250
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019189/ScoringFiles/PGS019189.txt.gz
PGS019190
(TPMI_427.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Paroxysmal tachycardia unspecified paroxysmal tachycardia 70
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019190/ScoringFiles/PGS019190.txt.gz
PGS019191
(TPMI_427.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Paroxysmal tachycardia unspecified paroxysmal tachycardia 215,523
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019191/ScoringFiles/PGS019191.txt.gz
PGS019192
(TPMI_427.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Paroxysmal tachycardia unspecified paroxysmal tachycardia 593,905
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019192/ScoringFiles/PGS019192.txt.gz
PGS019193
(TPMI_427.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Paroxysmal tachycardia unspecified paroxysmal tachycardia 983,780
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019193/ScoringFiles/PGS019193.txt.gz
PGS019194
(TPMI_427.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Paroxysmal tachycardia unspecified paroxysmal tachycardia 1,005,558
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019194/ScoringFiles/PGS019194.txt.gz
PGS019195
(TPMI_427.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atrial fibrillation and flutter atrial fibrillation 837
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019195/ScoringFiles/PGS019195.txt.gz
PGS019196
(TPMI_427.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atrial fibrillation and flutter atrial fibrillation 939,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019196/ScoringFiles/PGS019196.txt.gz
PGS019197
(TPMI_427.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atrial fibrillation and flutter atrial fibrillation 587,354
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019197/ScoringFiles/PGS019197.txt.gz
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