Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS005387
(TNBC_162_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 162
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005387/ScoringFiles/PGS005387.txt.gz
PGS005353
(DPRISM_T2DPRS_trainedforAFR_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 2,325,981
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005353/ScoringFiles/PGS005353.txt.gz
PGS005354
(DPRISM_T2DPRS_trainedforAFR_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,642,045
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005354/ScoringFiles/PGS005354.txt.gz
PGS005355
(DPRISM_T2DPRS_trainedforAFR_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 981,210
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005355/ScoringFiles/PGS005355.txt.gz
PGS005356
(DPRISM_T2DPRS_trainedforAFR_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,333,977
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005356/ScoringFiles/PGS005356.txt.gz
PGS005357
(DPRISM_T2DPRS_trainedforAFR_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,227
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005357/ScoringFiles/PGS005357.txt.gz
PGS005358
(DPRISM_T2DPRS_trainedforAMR_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,322,950
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005358/ScoringFiles/PGS005358.txt.gz
PGS005359
(DPRISM_T2DPRS_trainedforAMR_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,427,746
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005359/ScoringFiles/PGS005359.txt.gz
PGS005360
(DPRISM_T2DPRS_trainedforAMR_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 941,393
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005360/ScoringFiles/PGS005360.txt.gz
PGS005361
(DPRISM_T2DPRS_trainedforAMR_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,262,174
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005361/ScoringFiles/PGS005361.txt.gz
PGS005362
(DPRISM_T2DPRS_trainedforAMR_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,191,714
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005362/ScoringFiles/PGS005362.txt.gz
PGS005363
(DPRISM_T2DPRS_trainedforEAS_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 946,015
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005363/ScoringFiles/PGS005363.txt.gz
PGS005364
(DPRISM_T2DPRS_trainedforEAS_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 980,079
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005364/ScoringFiles/PGS005364.txt.gz
PGS005365
(DPRISM_T2DPRS_trainedforEAS_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,009,254
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005365/ScoringFiles/PGS005365.txt.gz
PGS005366
(DPRISM_T2DPRS_trainedforEAS_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 929,716
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005366/ScoringFiles/PGS005366.txt.gz
PGS005367
(DPRISM_T2DPRS_trainedforEAS_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 976,035
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005367/ScoringFiles/PGS005367.txt.gz
PGS005368
(DPRISM_T2DPRS_trainedforEUR_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,298,374
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005368/ScoringFiles/PGS005368.txt.gz
PGS005369
(DPRISM_T2DPRS_trainedforEUR_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,388,666
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005369/ScoringFiles/PGS005369.txt.gz
PGS005370
(DPRISM_T2DPRS_trainedforEUR_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 942,728
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005370/ScoringFiles/PGS005370.txt.gz
PGS005371
(DPRISM_T2DPRS_trainedforEUR_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,444,665
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005371/ScoringFiles/PGS005371.txt.gz
PGS005372
(DPRISM_T2DPRS_trainedforEUR_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,257,165
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005372/ScoringFiles/PGS005372.txt.gz
PGS005373
(DPRISM_T2DPRS_trainedforSAS_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,344,157
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005373/ScoringFiles/PGS005373.txt.gz
PGS005374
(DPRISM_T2DPRS_trainedforSAS_AMRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,419,570
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005374/ScoringFiles/PGS005374.txt.gz
PGS005375
(DPRISM_T2DPRS_trainedforSAS_EASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 983,905
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005375/ScoringFiles/PGS005375.txt.gz
PGS005376
(DPRISM_T2DPRS_trainedforSAS_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,386,504
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005376/ScoringFiles/PGS005376.txt.gz
PGS005377
(DPRISM_T2DPRS_trainedforSAS_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,327,177
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005377/ScoringFiles/PGS005377.txt.gz
PGS005350
(SBP)
 PGP000772 |
Øvretveit K et al. Eur J Prev Cardiol (2024)
 Systolic blood pressure systolic blood pressure 1,022,624
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005350/ScoringFiles/PGS005350.txt.gz
PGS005351
(DBP)
 PGP000772 |
Øvretveit K et al. Eur J Prev Cardiol (2024)
 Diastolic blood pressure diastolic blood pressure 1,024,311
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005351/ScoringFiles/PGS005351.txt.gz
PGS005352
(PP)
 PGP000772 |
Øvretveit K et al. Eur J Prev Cardiol (2024)
 Pulse Pressure pulse pressure measurement 1,022,643
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005352/ScoringFiles/PGS005352.txt.gz
PGS005345
(SCT)
 PGP000771 |
Tanha HM et al. Eur J Hum Genet (2026)
 Breast carcinoma breast carcinoma 435,538
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005345/ScoringFiles/PGS005345.txt.gz
PGS005346
(LDpred2)
 PGP000771 |
Tanha HM et al. Eur J Hum Genet (2026)
 Breast carcinoma breast carcinoma 961,355
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005346/ScoringFiles/PGS005346.txt.gz
PGS005347
(PRS-CS)
 PGP000771 |
Tanha HM et al. Eur J Hum Genet (2026)
 Breast carcinoma breast carcinoma 941,932
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005347/ScoringFiles/PGS005347.txt.gz
PGS005348
(SBayesR)
 PGP000771 |
Tanha HM et al. Eur J Hum Genet (2026)
 Breast carcinoma breast carcinoma 789,305
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005348/ScoringFiles/PGS005348.txt.gz
PGS005349
(SBayesRC)
 PGP000771 |
Tanha HM et al. Eur J Hum Genet (2026)
 Breast carcinoma breast carcinoma 5,387,266
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005349/ScoringFiles/PGS005349.txt.gz
PGS005324
(T2D_PRS_weighted)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,279,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005324/ScoringFiles/PGS005324.txt.gz
PGS005325
(T2D_PRS_unweighted)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,279,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005325/ScoringFiles/PGS005325.txt.gz
PGS005326
(T2D_PRS_AFR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,214,634
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005326/ScoringFiles/PGS005326.txt.gz
PGS005327
(T2D_PRS_AMR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 972,776
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005327/ScoringFiles/PGS005327.txt.gz
PGS005328
(T2D_PRS_EAS)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 570,349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005328/ScoringFiles/PGS005328.txt.gz
PGS005329
(T2D_PRS_EUR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,112,468
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005329/ScoringFiles/PGS005329.txt.gz
PGS005330
(T2D_PRS_SAS)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 642,349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005330/ScoringFiles/PGS005330.txt.gz
PGS005323
(PRS_CS_IPF)
 PGP000769 |
Zhu J et al. Am J Respir Crit Care Med (2025)
 Idiopathic pulmonary fibrosis idiopathic pulmonary fibrosis 653,482
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005323/ScoringFiles/PGS005323.txt.gz
PGS005322
(PRS_EC)
 PGP000768 |
Marston NA et al. Nat Med (2025)
 Coronary artery disease (Endothelial cell-related) coronary artery disorder 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005322/ScoringFiles/PGS005322.txt.gz
PGS005315
(ALM_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Appendicular lean mass lean body mass 630
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005315/ScoringFiles/PGS005315.txt.gz
PGS005316
(BFM_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Body fat mass body fat distribution 403
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005316/ScoringFiles/PGS005316.txt.gz
PGS005317
(DBP_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Diastolic blood pressure diastolic blood pressure 297
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005317/ScoringFiles/PGS005317.txt.gz
PGS005318
(eGFR_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 eGFR glomerular filtration rate 49
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005318/ScoringFiles/PGS005318.txt.gz
PGS005319
(HF_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Heart failure heart failure 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005319/ScoringFiles/PGS005319.txt.gz
PGS005320
(LPA_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Lipoprotein (a) lipoprotein A measurement 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005320/ScoringFiles/PGS005320.txt.gz
PGS005321
(SBP_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Systolic blood pressure systolic blood pressure 240
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005321/ScoringFiles/PGS005321.txt.gz
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