Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003649
(L_hippocampal_fissure_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal fissure volume hippocampal fissure volume 115,071
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003649/ScoringFiles/PGS003649.txt.gz
PGS019405
(TPMI_580_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Nephritis nephrosis renal sclerosis nephritis 114,961
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019405/ScoringFiles/PGS019405.txt.gz
PGS002056
(portability-ldpred2_451)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Phlebitis and thrombophlebitis Thrombophlebitis,
phlebitis		 114,679
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002056/ScoringFiles/PGS002056.txt.gz
PGS019791
(TPMI_BMI_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Body mass index (BMI) body mass index 114,184
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019791/ScoringFiles/PGS019791.txt.gz
PGS019702
(TPMI_724_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other and unspecified disorders of back Abnormality of the vertebral column 113,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019702/ScoringFiles/PGS019702.txt.gz
PGS000564
(PRSWEB_PHECODE184.11_Phelan-SIOC_LASSOSUM_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 110,710
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000564/ScoringFiles/PGS000564.txt.gz
PGS002486
(disease_CARDIOVASCULAR.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disorder 110,640
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002486/ScoringFiles/PGS002486.txt.gz
PGS001943
(portability-PLR_log_BMI)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Body mass index (BMI) body mass index 110,153
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001943/ScoringFiles/PGS001943.txt.gz
PGS019778
(TPMI_939_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 109,945
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019778/ScoringFiles/PGS019778.txt.gz
PGS005381
(Erpos_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor positive breast cancer estrogen-receptor positive breast cancer 109,933
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005381/ScoringFiles/PGS005381.txt.gz
PGS003199
(ExPRSweb_VitD_29343764-GCST005367_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 109,290
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003199/ScoringFiles/PGS003199.txt.gz
PGS002522
(biochemistry_Cholesterol.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Total cholesterol total cholesterol measurement 109,026
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002522/ScoringFiles/PGS002522.txt.gz
PGS003184
(ExPRSweb_VitD_29343764-GCST005367_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 108,547
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003184/ScoringFiles/PGS003184.txt.gz
PGS001951
(portability-PLR_log_fat_mass)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Whole body fat mass fat pad mass 107,776
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001951/ScoringFiles/PGS001951.txt.gz
PGS004640
(LDL_AFR_weighted_lassosum2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 107,449
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004640/ScoringFiles/PGS004640.txt.gz
PGS004645
(LDL_EAS_weighted_lassosum2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 107,449
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004645/ScoringFiles/PGS004645.txt.gz
PGS004650
(LDL_SAS_weighted_lassosum2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 107,449
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004650/ScoringFiles/PGS004650.txt.gz
PGS001917
(portability-PLR_fat_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Body fat percentage body fat percentage 107,244
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001917/ScoringFiles/PGS001917.txt.gz
PGS002518
(cov_SMOKING_STATUS.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Smoking status smoking status measurement 106,902
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002518/ScoringFiles/PGS002518.txt.gz
PGS002484
(body_BALDING1.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Balding Type 1 balding measurement 106,858
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002484/ScoringFiles/PGS002484.txt.gz
PGS002025
(portability-ldpred2_250.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 106,800
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002025/ScoringFiles/PGS002025.txt.gz
PGS018630
(TPMI_225_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Benign neoplasm of brain and other parts of nervous system benign neoplasm of peripheral nervous system 105,501
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018630/ScoringFiles/PGS018630.txt.gz
PGS019513
(TPMI_599.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Retention of urine Urinary retention 105,295
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019513/ScoringFiles/PGS019513.txt.gz
PGS002507
(biochemistry_LDLdirect.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 105,053
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002507/ScoringFiles/PGS002507.txt.gz
PGS004583
(PRSice_T2)
 PGP000563 |
Yang Z et al. Blood (2023)
 Platelet count during the second trimester platelet count 104,759
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004583/ScoringFiles/PGS004583.txt.gz
PGS005275
(CRC_PRS_JPHC_JPGWAS)
 PGP000749 |
Nakano S et al. Cancer Epidemiol (2025)
 Colorectal cancer colorectal carcinoma 104,677
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005275/ScoringFiles/PGS005275.txt.gz
PGS002453
(body_HEIGHTz.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Height body height 103,911
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002453/ScoringFiles/PGS002453.txt.gz
PGS002512
(mental_NEUROTICISM.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Neuroticism neuroticism measurement 103,865
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002512/ScoringFiles/PGS002512.txt.gz
PGS002488
(other_MORNINGPERSON.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Chronotype (morning person) chronotype measurement 103,314
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002488/ScoringFiles/PGS002488.txt.gz
PGS001958
(portability-PLR_log_hip_circ)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hip circumference hip circumference 103,123
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001958/ScoringFiles/PGS001958.txt.gz
PGS018910
(TPMI_290.11_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alzheimers disease Alzheimer disease 102,677
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018910/ScoringFiles/PGS018910.txt.gz
PGS002520
(pigment_TANNING.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Tanning suntan 100,837
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002520/ScoringFiles/PGS002520.txt.gz
PGS004018
(lassosum.CV.GCST008972.Gout)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Gout gout 100,595
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004018/ScoringFiles/PGS004018.txt.gz
PGS002493
(disease_ALLERGY_ECZEMA_DIAGNOSED.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Eczema Eczematoid dermatitis 100,504
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002493/ScoringFiles/PGS002493.txt.gz
PGS000762
(PRS_HD)
 PGP000165 |
Cherny SS et al. Eur J Hum Genet (2020)
 Hearing difficulty presbycusis 100,325
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000762/ScoringFiles/PGS000762.txt.gz
PGS003670
(R_hippocampus_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampus volume hippocampal volume 100,023
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003670/ScoringFiles/PGS003670.txt.gz
PGS002525
(biochemistry_VitaminD.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Vitamin D vitamin D level 99,894
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002525/ScoringFiles/PGS002525.txt.gz
PGS002820
(ExPRSweb_AgeAtMenopause_ieu-a-1004_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 99,745
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002820/ScoringFiles/PGS002820.txt.gz
PGS003187
(ExPRSweb_VitD_29343764-GCST005367_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 98,135
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003187/ScoringFiles/PGS003187.txt.gz
PGS000531
(PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 98,026
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000531/ScoringFiles/PGS000531.txt.gz
PGS018805
(TPMI_272.11_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypercholesterolemia Hypercholesterolemia 97,362
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018805/ScoringFiles/PGS018805.txt.gz
PGS002506
(disease_HYPOTHYROIDISM_SELF_REP.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypothyroidism hypothyroidism 97,010
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002506/ScoringFiles/PGS002506.txt.gz
PGS001983
(portability-PLR_log_waist_circ)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Waist circumference waist circumference 96,496
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001983/ScoringFiles/PGS001983.txt.gz
PGS002514
(disease_PSORIASIS.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 96,453
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002514/ScoringFiles/PGS002514.txt.gz
PGS004731
(Bilirubin_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Total bilirubin bilirubin measurement 96,003
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004731/ScoringFiles/PGS004731.txt.gz
PGS004014
(lassosum.CV.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 95,649
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004014/ScoringFiles/PGS004014.txt.gz
PGS019900
(TPMI_PP_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Pulse pressure pulse pressure measurement 95,561
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019900/ScoringFiles/PGS019900.txt.gz
PGS002521
(disease_THYROID_ANY_SELF_REP.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Thyroid (self-reported conditions) thyroid gland disorder 95,522
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002521/ScoringFiles/PGS002521.txt.gz
PGS002524
(disease_T2D.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 95,287
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002524/ScoringFiles/PGS002524.txt.gz
PGS002481
(disease_ASTHMA_DIAGNOSED.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Asthma asthma 95,252
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002481/ScoringFiles/PGS002481.txt.gz
Showing 3501 to 3550 of 6972 rows