Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001918
(portability-PLR_FEV1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Forced expiratory volume in 1-second (FEV1), Best measure forced expiratory volume 79,136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001918/ScoringFiles/PGS001918.txt.gz
PGS001959
(portability-PLR_log_HLR_reticulocyte)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 High light scatter reticulocyte count reticulocyte amount 78,803
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001959/ScoringFiles/PGS001959.txt.gz
PGS019799
(TPMI_HT_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Body height body height 78,139
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019799/ScoringFiles/PGS019799.txt.gz
PGS001945
(portability-PLR_log_creatinine)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Creatinine serum creatinine amount 76,800
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001945/ScoringFiles/PGS001945.txt.gz
PGS001965
(portability-PLR_log_lymphocyte)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Lymphocyte count lymphocyte count 76,535
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001965/ScoringFiles/PGS001965.txt.gz
PGS019497
(TPMI_597_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of urethra and urinary tract urinary system disorder 76,371
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019497/ScoringFiles/PGS019497.txt.gz
PGS001964
(portability-PLR_log_log_gammaGT)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Gamma-glutamyl transferase serum gamma-glutamyl transferase measurement 76,069
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001964/ScoringFiles/PGS001964.txt.gz
PGS003682
(L_molecular_layer_HP_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left molecular layer hippocampus proper body volume hippocampus molecular layer volume 75,245
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003682/ScoringFiles/PGS003682.txt.gz
PGS002010
(portability-PLR_urate)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Urate urate measurement 75,102
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002010/ScoringFiles/PGS002010.txt.gz
PGS001976
(portability-PLR_log_reticulocyte)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reticulocyte count reticulocyte count 75,033
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001976/ScoringFiles/PGS001976.txt.gz
PGS000337
(MetaPRS_CAD)
 PGP000104 |
Koyama S et al. Nat Genet (2020)
 Coronary artery disease coronary artery disorder 75,028
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000337/ScoringFiles/PGS000337.txt.gz - Check Terms/Licenses
PGS003671
(L_hippocampal_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal body volume hippocampal volume 74,820
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003671/ScoringFiles/PGS003671.txt.gz
PGS001888
(portability-PLR_apoA)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Apolipoprotein A apolipoprotein A 1 measurement 74,596
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001888/ScoringFiles/PGS001888.txt.gz
PGS003696
(R_parasubiculum_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right parasubiculum volume parasubiculum volume 73,898
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003696/ScoringFiles/PGS003696.txt.gz
PGS001927
(portability-PLR_hand_grip_strength)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hand grip strength (mean of both) grip strength measurement 73,846
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001927/ScoringFiles/PGS001927.txt.gz
PGS003643
(R_CA4_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA4 head volume hippocampal CA4 volume 73,791
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003643/ScoringFiles/PGS003643.txt.gz
PGS019888
(TPMI_BUN_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Blood urea nitrogen blood urea nitrogen amount 73,662
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019888/ScoringFiles/PGS019888.txt.gz
PGS001955
(portability-PLR_log_heel_BMD)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Heel bone mineral density (BMD) heel bone mineral density 73,565
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001955/ScoringFiles/PGS001955.txt.gz
PGS019138
(TPMI_401.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart and or renal disease hypertensive heart disease 73,378
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019138/ScoringFiles/PGS019138.txt.gz
PGS018429
(TPMI_070.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis B hepatitis B virus infection 73,098
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018429/ScoringFiles/PGS018429.txt.gz
PGS002949
(ExPRSweb_Glucose_MAGIC-FastingGlucose_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Glucose blood glucose amount 72,352
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002949/ScoringFiles/PGS002949.txt.gz
PGS018517
(TPMI_165_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Respiratory system cancer respiratory system cancer 72,170
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018517/ScoringFiles/PGS018517.txt.gz
PGS002929
(ExPRSweb_FPG_MAGIC-FastingGlucose_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Fasting plasma glucose blood glucose amount 71,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002929/ScoringFiles/PGS002929.txt.gz
PGS002083
(portability-ldpred2_696.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Psoriasis psoriasis 71,744
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002083/ScoringFiles/PGS002083.txt.gz
PGS001969
(portability-PLR_log_neutrophil)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Neutrophil count neutrophil count 71,566
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001969/ScoringFiles/PGS001969.txt.gz
PGS001946
(portability-PLR_log_CRP)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 71,444
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001946/ScoringFiles/PGS001946.txt.gz
PGS018565
(TPMI_189.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Bladder cancer urinary bladder cancer 71,443
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018565/ScoringFiles/PGS018565.txt.gz
PGS001979
(portability-PLR_log_triglycerides)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Triglycerides triglyceride measurement 71,203
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001979/ScoringFiles/PGS001979.txt.gz
PGS018527
(TPMI_174_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Breast cancer breast cancer 71,127
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018527/ScoringFiles/PGS018527.txt.gz
PGS003678
(R_fimbria_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right fimbria volume hippocampus fimbria volume 70,659
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003678/ScoringFiles/PGS003678.txt.gz
PGS018903
(TPMI_290.3_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 69,993
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018903/ScoringFiles/PGS018903.txt.gz
PGS019149
(TPMI_401.21_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hypertensive heart disease hypertensive heart disease 69,926
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019149/ScoringFiles/PGS019149.txt.gz
PGS019722
(TPMI_743_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Osteoporosis osteopenia and pathological fracture osteoporosis,
bone fracture		 69,652
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019722/ScoringFiles/PGS019722.txt.gz
PGS002001
(portability-PLR_protein)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Total protein total blood protein measurement 69,557
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002001/ScoringFiles/PGS002001.txt.gz
PGS001956
(portability-PLR_log_heel_BUA)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Heel Broadband ultrasound attenuation, direct entry heel bone mineral density 69,537
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001956/ScoringFiles/PGS001956.txt.gz
PGS001926
(portability-PLR_haemoglobin)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Haemoglobin concentration hemoglobin measurement 69,467
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001926/ScoringFiles/PGS001926.txt.gz
PGS018606
(TPMI_199_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neoplasm of uncertain behavior neoplasm 68,851
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018606/ScoringFiles/PGS018606.txt.gz
PGS018522
(TPMI_165.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of bronchus lung bronchus cancer 68,730
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018522/ScoringFiles/PGS018522.txt.gz
PGS019610
(TPMI_696_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis and related disorders psoriasis 68,664
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019610/ScoringFiles/PGS019610.txt.gz
PGS002009
(portability-PLR_systolic_BP)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Systolic blood pressure, automated reading systolic blood pressure 68,449
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002009/ScoringFiles/PGS002009.txt.gz
PGS001925
(portability-PLR_haematocrit_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Haematocrit percentage hematocrit 67,571
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001925/ScoringFiles/PGS001925.txt.gz
PGS003607
(L_HATA_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus-amygdala transition area volume hippocampal amigdala transition area volume 67,474
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003607/ScoringFiles/PGS003607.txt.gz
PGS002984
(ExPRSweb_Height_GIANT-Yang2012-height_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Height body height 67,333
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002984/ScoringFiles/PGS002984.txt.gz
PGS002974
(ExPRSweb_Height_GIANT-Yang2012-height_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Height body height 66,842
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002974/ScoringFiles/PGS002974.txt.gz
PGS001986
(portability-PLR_lymphocyte_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Lymphocyte percentage lymphocyte percentage of leukocytes 66,778
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001986/ScoringFiles/PGS001986.txt.gz
PGS018667
(TPMI_242_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Thyrotoxicosis with or without goiter thyrotoxicosis 66,615
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018667/ScoringFiles/PGS018667.txt.gz
PGS018555
(TPMI_182_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Malignant neoplasm of uterus tumor of uterus 66,480
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018555/ScoringFiles/PGS018555.txt.gz
PGS001900
(portability-PLR_diastolic_BP)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Diastolic blood pressure, automated reading diastolic blood pressure 66,335
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001900/ScoringFiles/PGS001900.txt.gz
PGS019432
(TPMI_585.3_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic renal failure CKD chronic kidney disease 66,304
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019432/ScoringFiles/PGS019432.txt.gz
PGS001971
(portability-PLR_log_platelet_volume)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Mean platelet (thrombocyte) volume platelet volume 65,450
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001971/ScoringFiles/PGS001971.txt.gz
Showing 3601 to 3650 of 6972 rows