Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019883
(TPMI_WBC_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 White blood cell count leukocyte quantity 297,127
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019883/ScoringFiles/PGS019883.txt.gz
PGS000117
(CVD_EJ2020)
 PGP000054 |
Elliott J et al. JAMA (2020)
 Cardiovascular disease cardiovascular disorder 297,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000117/ScoringFiles/PGS000117.txt.gz - Check Terms/Licenses
PGS004655
(logTG_AFR_weighted_lassosum2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Log triglycerides triglyceride measurement 298,999
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004655/ScoringFiles/PGS004655.txt.gz
PGS004660
(logTG_EAS_weighted_lassosum2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Log triglycerides triglyceride measurement 298,999
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004660/ScoringFiles/PGS004660.txt.gz
PGS004665
(logTG_SAS_weighted_lassosum2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Log triglycerides triglyceride measurement 298,999
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004665/ScoringFiles/PGS004665.txt.gz
PGS019897
(TPMI_LDL-C_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 LDL cholesterol LDL cholesterol 299,576
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019897/ScoringFiles/PGS019897.txt.gz
PGS019386
(TPMI_574.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cholelithiasis cholelithiasis 299,623
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019386/ScoringFiles/PGS019386.txt.gz
PGS018992
(TPMI_345.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Epilepsy epilepsy 300,225
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018992/ScoringFiles/PGS018992.txt.gz
PGS018840
(TPMI_277.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of purine and pyrimidine metabolism inborn disorder of purine or pyrimidine metabolism 300,267
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018840/ScoringFiles/PGS018840.txt.gz
PGS003847
(bmi_AFR_PRSCSx)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Body mass index (BMI) body mass index 300,864
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003847/ScoringFiles/PGS003847.txt.gz
PGS003840
(height_AFR_PRSCSx)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Height body height 300,880
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003840/ScoringFiles/PGS003840.txt.gz
PGS019381
(TPMI_574_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cholelithiasis and cholecystitis cholelithiasis 301,092
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019381/ScoringFiles/PGS019381.txt.gz
PGS019236
(TPMI_433.3_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cerebral ischemia Cerebral ischemia 306,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019236/ScoringFiles/PGS019236.txt.gz
PGS012528
(OSA_bmi_unadj_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea obstructive sleep apnea syndrome 307,286
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012528/ScoringFiles/PGS012528.txt.gz
PGS019573
(TPMI_681.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cellulitis and abscess of fingers toes abscess,
cellulitis		 309,069
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019573/ScoringFiles/PGS019573.txt.gz
PGS002669
(biochemistry_Cholesterol.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Total cholesterol total cholesterol measurement 309,475
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002669/ScoringFiles/PGS002669.txt.gz
PGS018719
(TPMI_250_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diabetes mellitus diabetes mellitus 309,556
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018719/ScoringFiles/PGS018719.txt.gz
PGS002778
(GTG_Hypertension_SCT)
 PGP000365 |
Wong CK et al. PLoS One (2022)
 Incident hypertension hypertensive disorder 309,759
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002778/ScoringFiles/PGS002778.txt.gz - Check Terms/Licenses
PGS018636
(TPMI_226_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Benign neoplasm of thyroid glands benign thyroid gland neoplasm 310,396
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018636/ScoringFiles/PGS018636.txt.gz
PGS003179
(ExPRSweb_VitD_100021-raw_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 310,479
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003179/ScoringFiles/PGS003179.txt.gz
PGS002018
(portability-ldpred2_193)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Thyroid cancer thyroid gland carcinoma 311,520
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002018/ScoringFiles/PGS002018.txt.gz
PGS003109
(ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 311,565
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003109/ScoringFiles/PGS003109.txt.gz
PGS003174
(ExPRSweb_VitD_100021-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 312,224
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003174/ScoringFiles/PGS003174.txt.gz
PGS002999
(ExPRSweb_Hypertension_20002-1072_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 313,080
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002999/ScoringFiles/PGS002999.txt.gz
PGS003159
(ExPRSweb_VitB12_100013-raw_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin B12 vitamin B12 measurement 313,902
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003159/ScoringFiles/PGS003159.txt.gz
PGS019017
(TPMI_362.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Degeneration of macula and posterior pole of retina degeneration of macula and posterior pole 314,377
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019017/ScoringFiles/PGS019017.txt.gz
PGS003154
(ExPRSweb_VitB12_100013-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin B12 vitamin B12 measurement 314,838
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003154/ScoringFiles/PGS003154.txt.gz
PGS019256
(TPMI_452_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other venous embolism and thrombosis deep vein thrombosis 315,453
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019256/ScoringFiles/PGS019256.txt.gz
PGS002102
(portability-ldpred2_apoB)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Apolipoprotein B apolipoprotein B measurement 315,483
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002102/ScoringFiles/PGS002102.txt.gz
PGS004011
(lassosum.auto.GCST90018959.Height)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Height body height 315,596
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004011/ScoringFiles/PGS004011.txt.gz
PGS004021
(lassosum.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 315,740
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004021/ScoringFiles/PGS004021.txt.gz
PGS002874
(ExPRSweb_CRP_prot-a-670_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 316,203
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002874/ScoringFiles/PGS002874.txt.gz
PGS019728
(TPMI_743.11_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Osteoporosis NOS osteoporosis 317,022
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019728/ScoringFiles/PGS019728.txt.gz
PGS019396
(TPMI_575.6_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cholesterolosis of gallbladder isolated agenesis of gallbladder 317,692
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019396/ScoringFiles/PGS019396.txt.gz
PGS018702
(TPMI_245.21_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic lymphocytic thyroiditis Hashimoto thyroiditis 318,664
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018702/ScoringFiles/PGS018702.txt.gz
PGS018905
(TPMI_290.3_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 322,143
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018905/ScoringFiles/PGS018905.txt.gz
PGS019528
(TPMI_604_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Disorders of penis penile disorder 322,262
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019528/ScoringFiles/PGS019528.txt.gz
PGS004902
(PRSBMI)
 PGP000631 |
Chikowore T et al. Genome Med (2024)
 Body mass index (BMI) body mass index 322,639
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004902/ScoringFiles/PGS004902.txt.gz
PGS019063
(TPMI_371.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Uveitis noninfectious or NOS uveitis 323,165
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019063/ScoringFiles/PGS019063.txt.gz
PGS019568
(TPMI_626.13_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Irregular menstrual cycle menstrual disorder 323,552
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019568/ScoringFiles/PGS019568.txt.gz
PGS012529
(OSA_bmi_adj_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea (adjusted for BMI) obstructive sleep apnea syndrome 323,621
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012529/ScoringFiles/PGS012529.txt.gz
PGS002919
(ExPRSweb_Estradiol_30800-raw_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estradiol estradiol measurement 324,623
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002919/ScoringFiles/PGS002919.txt.gz
PGS002673
(body_WHRadjBMIz.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Waist-hip ratio waist-hip ratio 325,206
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002673/ScoringFiles/PGS002673.txt.gz
PGS002738
(PRS_AUD)
 PGP000345 |
Lai D et al. Alcohol Clin Exp Res (2022)
 Alcohol use disorder alcohol dependence 326,000
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002738/ScoringFiles/PGS002738.txt.gz
PGS002914
(ExPRSweb_Estradiol_30800-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estradiol estradiol measurement 326,223
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002914/ScoringFiles/PGS002914.txt.gz
PGS019341
(TPMI_550_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abdominal hernia ventral hernia 328,473
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019341/ScoringFiles/PGS019341.txt.gz
PGS003209
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Sleep apnea sleep apnea syndrome 328,671
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003209/ScoringFiles/PGS003209.txt.gz
PGS019618
(TPMI_696.41_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis vulgaris psoriasis vulgaris 330,044
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019618/ScoringFiles/PGS019618.txt.gz
PGS002672
(biochemistry_VitaminD.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Vitamin D vitamin D level 330,506
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002672/ScoringFiles/PGS002672.txt.gz
PGS018927
(TPMI_292_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neurological disorders nervous system disorder 330,541
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018927/ScoringFiles/PGS018927.txt.gz
Showing 3701 to 3750 of 6972 rows