Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS002218
(portability-ldpred2_poorer_health)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Overall health rating health trait 958,362
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002218/ScoringFiles/PGS002218.txt.gz
PGS003872
(LDL_PRScsx_ARB_EASweights)
PGP000501 |
Shim I et al. Nature Communications (2023)
LDL cholesterol low density lipoprotein cholesterol measurement 958,649
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003872/ScoringFiles/PGS003872.txt.gz
PGS003878
(HDL_PRScsx_ARB_EASweights)
PGP000501 |
Shim I et al. Nature Communications (2023)
HDL cholesterol high density lipoprotein cholesterol measurement 958,649
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003878/ScoringFiles/PGS003878.txt.gz
PGS005244
(T2D_PRS_PRS_CSx_META_F_AMR)
PGP000742 |
Guo B G et al. Nat Commun (2025)
Type 2 diabetes (T2D) type 2 diabetes mellitus 960,470
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005244/ScoringFiles/PGS005244.txt.gz
PGS004149
(sbayesr.auto.GCST90018959.Height)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Height body height 962,278
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004149/ScoringFiles/PGS004149.txt.gz
PGS003277
(ExPRSweb_Creatine_eGFRcrea-overall-IV-2GC_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine level
963,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003277/ScoringFiles/PGS003277.txt.gz
PGS002785
(SCZ_SDPR)
PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
Schizophrenia schizophrenia 964,422
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002785/ScoringFiles/PGS002785.txt.gz
PGS005238
(LDpred2)
PGP000741 |
Tanha HM et al. HGG Adv (2025)
Prostate carcinoma prostate carcinoma 964,607
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005238/ScoringFiles/PGS005238.txt.gz
PGS005122
(forAFR_fromAMR)
PGP000703 |
Tsuo K et al. Cell Genom (2022)
Asthma asthma 965,078
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005122/ScoringFiles/PGS005122.txt.gz
PGS002680
(body_BALDING1.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Balding Type 1 balding measurement 965,079
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002680/ScoringFiles/PGS002680.txt.gz
PGS005137
(forSAS_fromAMR)
PGP000703 |
Tsuo K et al. Cell Genom (2022)
Asthma asthma 965,403
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005137/ScoringFiles/PGS005137.txt.gz
PGS005132
(forEUR_fromAMR)
PGP000703 |
Tsuo K et al. Cell Genom (2022)
Asthma asthma 965,696
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005132/ScoringFiles/PGS005132.txt.gz
PGS002143
(portability-ldpred2_hand_grip_strength)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Hand grip strength (mean of both) grip strength measurement 966,283
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002143/ScoringFiles/PGS002143.txt.gz
PGS002202
(portability-ldpred2_log_water_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body water mass whole body water mass 966,737
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002202/ScoringFiles/PGS002202.txt.gz
PGS002168
(portability-ldpred2_log_fat_free_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body fat-free mass lean body mass 966,825
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002168/ScoringFiles/PGS002168.txt.gz
PGS002694
(biochemistry_Glucose.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Glucose glucose measurement 969,640
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002694/ScoringFiles/PGS002694.txt.gz
PGS002703
(biochemistry_LDLdirect.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
LDL cholesterol low density lipoprotein cholesterol measurement 970,081
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002703/ScoringFiles/PGS002703.txt.gz
PGS005280
(IgE_GWAS_9260_Japanese_individuals_rev2.EAS)
PGP000752 |
Sutoh Y et al. Am J Hum Genet (2025)
Total IgE immunoglobulin E measurement 970,856
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005280/ScoringFiles/PGS005280.txt.gz
PGS002695
(biochemistry_HDLcholesterol.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
HDL cholesterol high density lipoprotein cholesterol measurement 971,682
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002695/ScoringFiles/PGS002695.txt.gz
PGS000135
(SCZ_MTS)
PGP000065 |
Zheutlin AB et al. Am J Psychiatry (2019)
Schizophrenia schizophrenia 972,439
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000135/ScoringFiles/PGS000135.txt.gz
PGS005327
(T2D_PRS_AMR)
PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
Type 2 Diabetes Mellitus type 2 diabetes mellitus 972,776
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005327/ScoringFiles/PGS005327.txt.gz
PGS002156
(portability-ldpred2_log_age_first_sex)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Age first had sexual intercourse age at first sexual intercourse measurement 972,919
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002156/ScoringFiles/PGS002156.txt.gz
PGS002682
(disease_CARDIOVASCULAR.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Cardiovascular disease cardiovascular disease 972,965
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002682/ScoringFiles/PGS002682.txt.gz
PGS002701
(disease_HYPERTENSION_DIAGNOSED.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Hypertension hypertension 973,782
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002701/ScoringFiles/PGS002701.txt.gz
PGS002706
(blood_MEAN_PLATELET_VOL.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Mean platelet volume platelet volume 973,986
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002706/ScoringFiles/PGS002706.txt.gz
PGS004783
(HLD_PRSmix_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Hypercholesterolemia Hypercholesterolemia 975,107
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004783/ScoringFiles/PGS004783.txt.gz
PGS002801
(GIANT_HEIGHT_YENGO_2022_PGS_WEIGHTS_AFR)
PGP000382 |
Yengo L et al. Nature (2022)
Height body height 975,455
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002801/ScoringFiles/PGS002801.txt.gz
PGS004160
(UKBB_EnsPGS.GCST008972.Gout)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Gout gout 976,174
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004160/ScoringFiles/PGS004160.txt.gz
PGS002712
(blood_RBC_DISTRIB_WIDTH.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red blood cell distribution width Red cell distribution width 976,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002712/ScoringFiles/PGS002712.txt.gz
PGS004090
(prscs.auto.GCST008972.Gout)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Gout gout 976,777
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004090/ScoringFiles/PGS004090.txt.gz
PGS004091
(prscs.auto.GCST008972.Urate)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Urate urate measurement 976,777
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004091/ScoringFiles/PGS004091.txt.gz
PGS002718
(biochemistry_Cholesterol.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Total cholesterol total cholesterol measurement 977,049
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002718/ScoringFiles/PGS002718.txt.gz
PGS002684
(other_MORNINGPERSON.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Chronotype (morning person) chronotype measurement 977,159
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002684/ScoringFiles/PGS002684.txt.gz
PGS002176
(portability-ldpred2_log_hip_circ)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Hip circumference hip circumference 977,411
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002176/ScoringFiles/PGS002176.txt.gz
PGS002179
(portability-ldpred2_log_impedance)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Impedance of whole body body composition measurement 978,109
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002179/ScoringFiles/PGS002179.txt.gz
PGS003962
(DBP_EAS)
PGP000510 |
Kurniansyah N et al. Nat Commun (2023)
Diastolic blood pressure diastolic blood pressure 978,280
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003962/ScoringFiles/PGS003962.txt.gz
PGS003966
(SBP_EAS)
PGP000510 |
Kurniansyah N et al. Nat Commun (2023)
Systolic blood pressure systolic blood pressure 978,280
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003966/ScoringFiles/PGS003966.txt.gz
PGS003490
(cont-decay-ankle_spacing)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Ankle spacing width body weights and measures 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003490/ScoringFiles/PGS003490.txt.gz
PGS003491
(cont-decay-apoA)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Apolipoprotein A apolipoprotein A-IV measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003491/ScoringFiles/PGS003491.txt.gz
PGS003492
(cont-decay-apoB)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Apolipoprotein B apolipoprotein B measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003492/ScoringFiles/PGS003492.txt.gz
PGS003493
(cont-decay-avMSE)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
avMSE visual acuity measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003493/ScoringFiles/PGS003493.txt.gz
PGS003494
(cont-decay-birth_weight)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Birth weight birth weight 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003494/ScoringFiles/PGS003494.txt.gz
PGS003495
(cont-decay-cholesterol)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Cholesterol total cholesterol measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003495/ScoringFiles/PGS003495.txt.gz
PGS003496
(cont-decay-darker_hair0)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Hair color (natural, before greying) strand of hair color 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003496/ScoringFiles/PGS003496.txt.gz
PGS003497
(cont-decay-depressed_for_1w)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Ever depressed for a whole week depressive episode measurement 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003497/ScoringFiles/PGS003497.txt.gz
PGS003498
(cont-decay-diastolic_BP)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Diastolic blood pressure, automated reading diastolic blood pressure 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003498/ScoringFiles/PGS003498.txt.gz
PGS003499
(cont-decay-ECG_PQ_interval)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
PQ interval PR interval 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003499/ScoringFiles/PGS003499.txt.gz
PGS003500
(cont-decay-ECG_QT_interval)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
QT interval QT interval 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003500/ScoringFiles/PGS003500.txt.gz
PGS003501
(cont-decay-ECG_QTC_interval)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
QTc interval QT interval 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003501/ScoringFiles/PGS003501.txt.gz
PGS003502
(cont-decay-erythrocyte)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Red blood cell (erythrocyte) count erythrocyte count 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003502/ScoringFiles/PGS003502.txt.gz