Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS005152
(Coronary artery disease (PRS-CSx; EAS+EUR))
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Coronary artery disease coronary artery disorder 943,274
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005152/ScoringFiles/PGS005152.txt.gz
PGS002789
(MDD_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Major depressive disorder major depressive disorder 943,784
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002789/ScoringFiles/PGS002789.txt.gz
PGS005120
(PGS_Teixeira_2024_SBP)
 PGP000702 |
Teixeira SK et al. Sci Rep (2024)
 Systolic blood pressure systolic blood pressure 944,279
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005120/ScoringFiles/PGS005120.txt.gz
PGS004139
(sbayesr.auto.GCST006085.Prostate_cancer)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Prostate cancer prostate carcinoma 945,385
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004139/ScoringFiles/PGS004139.txt.gz
PGS003103
(ExPRSweb_T2D_30054458-GCST006867_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 945,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003103/ScoringFiles/PGS003103.txt.gz
PGS003118
(ExPRSweb_T2D_30054458-GCST006867_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 945,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003118/ScoringFiles/PGS003118.txt.gz
PGS005363
(DPRISM_T2DPRS_trainedforEAS_AFRweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 946,015
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005363/ScoringFiles/PGS005363.txt.gz
PGS002152
(portability-ldpred2_less_alcohol)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Alcohol intake frequency alcohol consumption quality 946,965
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002152/ScoringFiles/PGS002152.txt.gz
PGS002716
(pigment_TANNING.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Tanning suntan 947,237
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002716/ScoringFiles/PGS002716.txt.gz
PGS002786
(BD_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Bipolar disorder bipolar disorder 948,996
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002786/ScoringFiles/PGS002786.txt.gz
PGS002213
(portability-ldpred2_neuroticism)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Neuroticism score neuroticism measurement 950,183
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002213/ScoringFiles/PGS002213.txt.gz
PGS004691
(lung_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Lung cancer lung carcinoma 950,353
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004691/ScoringFiles/PGS004691.txt.gz
PGS004137
(sbayesr.auto.GCST004988.Breast_cancer)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Breast cancer breast carcinoma 950,524
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004137/ScoringFiles/PGS004137.txt.gz
PGS002231
(portability-ldpred2_years_of_edu)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Qualifications (years of education) educational attainment 950,845
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002231/ScoringFiles/PGS002231.txt.gz
PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Knee osteoarthritis osteoarthritis, knee 952,133
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004883/ScoringFiles/PGS004883.txt.gz
PGS002683
(repro_ChildLess.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Childless reproductive behavior trait 954,898
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002683/ScoringFiles/PGS002683.txt.gz
PGS002209
(portability-ldpred2_more_evening)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Morning/evening person (chronotype) chronotype measurement 955,439
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002209/ScoringFiles/PGS002209.txt.gz
PGS004938
(pgs_data_ldpred)
 PGP000666 |
Kovalenko E et al. Front Med (Lausanne) (2024)
 Severe COVID-19 course COVID-19 955,503
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004938/ScoringFiles/PGS004938.txt.gz
PGS002139
(portability-ldpred2_geek_time)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Time spent watching television (TV) or using computer lifestyle measurement 956,532
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002139/ScoringFiles/PGS002139.txt.gz
PGS002689
(disease_ALLERGY_ECZEMA_DIAGNOSED.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Eczema Eczematoid dermatitis 957,578
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002689/ScoringFiles/PGS002689.txt.gz
PGS004024
(ldpred2.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 958,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004024/ScoringFiles/PGS004024.txt.gz
PGS004039
(ldpred2.CV.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 958,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004039/ScoringFiles/PGS004039.txt.gz
PGS002218
(portability-ldpred2_poorer_health)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Overall health rating health trait 958,362
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002218/ScoringFiles/PGS002218.txt.gz
PGS003872
(LDL_PRScsx_ARB_EASweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 958,649
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003872/ScoringFiles/PGS003872.txt.gz
PGS003878
(HDL_PRScsx_ARB_EASweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 958,649
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003878/ScoringFiles/PGS003878.txt.gz
PGS005244
(T2D_PRS_PRS_CSx_META_F_AMR)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 960,470
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005244/ScoringFiles/PGS005244.txt.gz
PGS005346
(LDpred2)
 PGP000771 |
Tanha HM et al. Eur J Hum Genet (2026)
 Breast carcinoma breast carcinoma 961,355
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005346/ScoringFiles/PGS005346.txt.gz
PGS004149
(sbayesr.auto.GCST90018959.Height)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Height body height 962,278
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004149/ScoringFiles/PGS004149.txt.gz
PGS003277
(ExPRSweb_Creatine_eGFRcrea-overall-IV-2GC_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine level		 963,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003277/ScoringFiles/PGS003277.txt.gz
PGS002785
(SCZ_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Schizophrenia schizophrenia 964,422
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002785/ScoringFiles/PGS002785.txt.gz
PGS005238
(LDpred2)
 PGP000741 |
Tanha HM et al. HGG Adv (2025)
 Prostate carcinoma prostate carcinoma 964,607
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005238/ScoringFiles/PGS005238.txt.gz
PGS005122
(forAFR_fromAMR)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 965,078
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005122/ScoringFiles/PGS005122.txt.gz
PGS002680
(body_BALDING1.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Balding Type 1 balding measurement 965,079
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002680/ScoringFiles/PGS002680.txt.gz
PGS005137
(forSAS_fromAMR)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 965,403
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005137/ScoringFiles/PGS005137.txt.gz
PGS005132
(forEUR_fromAMR)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 965,696
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005132/ScoringFiles/PGS005132.txt.gz
PGS002143
(portability-ldpred2_hand_grip_strength)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hand grip strength (mean of both) grip strength measurement 966,283
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002143/ScoringFiles/PGS002143.txt.gz
PGS002202
(portability-ldpred2_log_water_mass)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Whole body water mass whole body water mass 966,737
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002202/ScoringFiles/PGS002202.txt.gz
PGS002168
(portability-ldpred2_log_fat_free_mass)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Whole body fat-free mass lean body mass 966,825
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002168/ScoringFiles/PGS002168.txt.gz
PGS012545
(EN_model_IS)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Ischemic stroke Ischemic stroke 969,253
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012545/ScoringFiles/PGS012545.txt.gz
PGS012544
(EN_model_HF)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Heart failure heart failure 969,507
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012544/ScoringFiles/PGS012544.txt.gz
PGS002694
(biochemistry_Glucose.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Glucose glucose measurement 969,640
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002694/ScoringFiles/PGS002694.txt.gz
PGS012541
(EN_model_Asthma)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Asthma Asthma 969,763
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012541/ScoringFiles/PGS012541.txt.gz
PGS012543
(EN_model_CKD)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Chronic kidney disease chronic kidney disease 969,768
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012543/ScoringFiles/PGS012543.txt.gz
PGS012540
(EN_model_Angina)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Angina angina pectoris 969,769
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012540/ScoringFiles/PGS012540.txt.gz
PGS012542
(EN_model_CAD)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Coronary artery disease coronary artery disorder 969,769
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012542/ScoringFiles/PGS012542.txt.gz
PGS012546
(EN_model_PAD)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Peripheral arterial disease peripheral arterial disease 969,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012546/ScoringFiles/PGS012546.txt.gz
PGS012547
(EN_model_T2D)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Type 2 diabetes mellitus type 2 diabetes mellitus 969,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012547/ScoringFiles/PGS012547.txt.gz
PGS002703
(biochemistry_LDLdirect.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 970,081
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002703/ScoringFiles/PGS002703.txt.gz
PGS005280
(IgE_GWAS_9260_Japanese_individuals_rev2.EAS)
 PGP000752 |
Sutoh Y et al. Am J Hum Genet (2025)
 Total IgE immunoglobulin E measurement 970,856
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005280/ScoringFiles/PGS005280.txt.gz
PGS002695
(biochemistry_HDLcholesterol.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 HDL cholesterol high density lipoprotein cholesterol measurement 971,682
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002695/ScoringFiles/PGS002695.txt.gz
Showing 3901 to 3950 of 5450 rows