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PGS Catalog
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Polygenic Scores (PGS)
Polygenic Scores (PGS)
Filter PGS by Participant Ancestry
Individuals included in:
Any Stage [G, D, E]
All Stages combined [G + D + E]
Development [G, D]
- GWAS [G]
- Score development [D]
PGS Evaluation [E]
G
- Source of Variant Associations (
G
WAS)
D
- Score
D
evelopment/Training
E
- PGS
E
valuation
List of ancestries includes:
--
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Display options:
Show European ancestry data
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only
Multi-ancestry data
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name
PGS Publication ID
(PGP)
Reported Trait
Mapped Trait(s)
(Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File
(FTP Link)
PGS000012
(GRS49K)
PGP000005
|
Abraham G
et al.
Eur Heart J (2016)
Coronary artery disease
coronary artery disease
49,310
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000012/ScoringFiles/PGS000012.txt.gz
PGS000013
(GPS_CAD)
PGP000006
|
Khera AV
et al.
Nat Genet (2018)
Coronary artery disease
coronary artery disease
6,630,150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000013/ScoringFiles/PGS000013.txt.gz
- Check
Terms/Licenses
PGS000018
(metaGRS_CAD)
PGP000007
|
Inouye M
et al.
J Am Coll Cardiol (2018)
Coronary artery disease
coronary artery disease
1,745,179
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000018/ScoringFiles/PGS000018.txt.gz
PGS000019
(GRS_CAD)
PGP000009
|
Paquette M
et al.
J Clin Lipidol (2017)
Coronary artery disease
coronary artery disease
192
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000019/ScoringFiles/PGS000019.txt.gz
PGS000058
(CAD_GRS_204)
PGP000043
|
Morieri ML
et al.
Diabetes Care (2018)
Coronary artery disease
coronary artery disease
204
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000058/ScoringFiles/PGS000058.txt.gz
PGS000116
(CAD_EJ2020)
PGP000054
|
Elliott J
et al.
JAMA (2020)
Coronary artery disease
coronary artery disease
40,079
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000116/ScoringFiles/PGS000116.txt.gz
- Check
Terms/Licenses
PGS000296
(GPS_CAD_SA)
PGP000090
|
Wang M
et al.
J Am Coll Cardiol (2020)
Coronary artery disease
coronary artery disease
6,630,150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000296/ScoringFiles/PGS000296.txt.gz
- Check
Terms/Licenses
PGS000337
(MetaPRS_CAD)
PGP000104
|
Koyama S
et al.
Nat Genet (2020)
Coronary artery disease
coronary artery disease
75,028
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000337/ScoringFiles/PGS000337.txt.gz
- Check
Terms/Licenses
PGS000349
(PRS70_CAD)
PGP000114
|
Pechlivanis S
et al.
BMC Med Genet (2020)
Coronary artery disease
coronary artery disease
70
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000349/ScoringFiles/PGS000349.txt.gz
PGS000746
(PRS_UKB)
PGP000152
|
Gola D
et al.
Circ Genom Precis Med (2020)
Coronary artery disease
coronary artery disease
1,940
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000746/ScoringFiles/PGS000746.txt.gz
PGS000747
(PRS_EB)
PGP000152
|
Gola D
et al.
Circ Genom Precis Med (2020)
Coronary artery disease
coronary artery disease
375,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000747/ScoringFiles/PGS000747.txt.gz
PGS000748
(PRS_DE)
PGP000152
|
Gola D
et al.
Circ Genom Precis Med (2020)
Coronary artery disease
coronary artery disease
3,423,987
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000748/ScoringFiles/PGS000748.txt.gz
PGS000749
(PRS_COMBINED)
PGP000152
|
Gola D
et al.
Circ Genom Precis Med (2020)
Coronary artery disease
coronary artery disease
1,056,021
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000749/ScoringFiles/PGS000749.txt.gz
PGS001355
(CAD_AnnoPred_PRS)
PGP000252
|
Ye Y
et al.
Circ Genom Precis Med (2021)
Coronary artery disease
coronary artery disease
2,994,055
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001355/ScoringFiles/PGS001355.txt.gz
PGS002244
(ldpred_cad)
PGP000271
|
Mars N
et al.
Cell Genom (2022)
Coronary artery disease
coronary artery disease
6,576,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002244/ScoringFiles/PGS002244.txt.gz
PGS002262
(metaPRS_CAD)
PGP000289
|
Lu X
et al.
Eur Heart J (2022)
Coronary artery disease
coronary artery disease
540
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002262/ScoringFiles/PGS002262.txt.gz
PGS002809
(GRS_CAD)
PGP000388
|
Ahmed R
et al.
Int J Cardiol Heart Vasc (2022)
Coronary artery disease
coronary artery disease
205
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002809/ScoringFiles/PGS002809.txt.gz
PGS003355
(1MH_CAD_PRS_2015_Ldpred)
PGP000409
|
Aragam KG
et al.
Nat Genet (2022)
Coronary artery disease
coronary artery disease
1,532,758
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003355/ScoringFiles/PGS003355.txt.gz
PGS003356
(1MH_CAD_PRS_2022_Ldpred)
PGP000409
|
Aragam KG
et al.
Nat Genet (2022)
Coronary artery disease
coronary artery disease
2,324,683
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003356/ScoringFiles/PGS003356.txt.gz
PGS003438
(PRS241_CAD)
PGP000440
|
Marston NA
et al.
JAMA Cardiol (2023)
Coronary artery disease
coronary artery disease
241
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003438/ScoringFiles/PGS003438.txt.gz
PGS003446
(TEM_CAD_PRS)
PGP000446
|
Tcheandjieu C
et al.
Nat Med (2022)
Coronary artery disease
coronary artery disease
538,084
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003446/ScoringFiles/PGS003446.txt.gz
PGS003725
(GPS_Mult)
PGP000466
|
Patel AP
et al.
Nat Med (2023)
Coronary artery disease
coronary artery disease
1,296,172
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003725/ScoringFiles/PGS003725.txt.gz
PGS003726
(GPS_CADANC)
PGP000466
|
Patel AP
et al.
Nat Med (2023)
Coronary artery disease
coronary artery disease
1,296,172
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003726/ScoringFiles/PGS003726.txt.gz
PGS003727
(GPS_CADEUR)
PGP000466
|
Patel AP
et al.
Nat Med (2023)
Coronary artery disease
coronary artery disease
1,125,113
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003727/ScoringFiles/PGS003727.txt.gz
PGS003866
(CAD_lassosum2_ARB)
PGP000501
|
Shim I
et al.
Nature Communications (2023)
Coronary artery disease
coronary artery disease
10,440
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003866/ScoringFiles/PGS003866.txt.gz
PGS004196
(cad_1)
PGP000520
|
Raben TG
et al.
Sci Rep (2023)
Coronary artery disease
coronary artery disease
3,892
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004196/ScoringFiles/PGS004196.txt.gz
PGS004197
(cad_2)
PGP000520
|
Raben TG
et al.
Sci Rep (2023)
Coronary artery disease
coronary artery disease
11,490
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004197/ScoringFiles/PGS004197.txt.gz
PGS004198
(cad_3)
PGP000520
|
Raben TG
et al.
Sci Rep (2023)
Coronary artery disease
coronary artery disease
5,723
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004198/ScoringFiles/PGS004198.txt.gz
PGS004199
(cad_4)
PGP000520
|
Raben TG
et al.
Sci Rep (2023)
Coronary artery disease
coronary artery disease
6,085
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004199/ScoringFiles/PGS004199.txt.gz
PGS004200
(cad_5)
PGP000520
|
Raben TG
et al.
Sci Rep (2023)
Coronary artery disease
coronary artery disease
8,361
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004200/ScoringFiles/PGS004200.txt.gz
PGS004305
(GenoBoost_coronary_artery_disease_0)
PGP000546
|
Ohta R
et al.
Nat Commun (2024)
Coronary artery disease
coronary artery disease
3,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004305/ScoringFiles/PGS004305.txt.gz
PGS004306
(GenoBoost_coronary_artery_disease_1)
PGP000546
|
Ohta R
et al.
Nat Commun (2024)
Coronary artery disease
coronary artery disease
4,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004306/ScoringFiles/PGS004306.txt.gz
PGS004307
(GenoBoost_coronary_artery_disease_2)
PGP000546
|
Ohta R
et al.
Nat Commun (2024)
Coronary artery disease
coronary artery disease
4,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004307/ScoringFiles/PGS004307.txt.gz
PGS004308
(GenoBoost_coronary_artery_disease_3)
PGP000546
|
Ohta R
et al.
Nat Commun (2024)
Coronary artery disease
coronary artery disease
1,500
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004308/ScoringFiles/PGS004308.txt.gz
PGS004309
(GenoBoost_coronary_artery_disease_4)
PGP000546
|
Ohta R
et al.
Nat Commun (2024)
Coronary artery disease
coronary artery disease
3,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004309/ScoringFiles/PGS004309.txt.gz
PGS004743
(cad_PRSmix_eur)
PGP000604
|
Truong B
et al.
Cell Genom (2024)
Coronary artery disease
coronary artery disease
3,606,321
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004743/ScoringFiles/PGS004743.txt.gz
PGS004744
(cad_PRSmix_sas)
PGP000604
|
Truong B
et al.
Cell Genom (2024)
Coronary artery disease
coronary artery disease
7,082,943
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004744/ScoringFiles/PGS004744.txt.gz
PGS004745
(cad_PRSmixPlus_eur)
PGP000604
|
Truong B
et al.
Cell Genom (2024)
Coronary artery disease
coronary artery disease
4,769,577
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004745/ScoringFiles/PGS004745.txt.gz
PGS004746
(cad_PRSmixPlus_sas)
PGP000604
|
Truong B
et al.
Cell Genom (2024)
Coronary artery disease
coronary artery disease
6,483,064
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004746/ScoringFiles/PGS004746.txt.gz
PGS004921
(CAD-GRS)
PGP000654
|
Huang Y
et al.
Circ Genom Precis Med (2020)
Coronary artery disease
coronary artery disease
161
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004921/ScoringFiles/PGS004921.txt.gz
PGS004941
(CAD_MetaPRS)
PGP000668
|
China Kadoorie Biobank Collaborative Group.
et al.
Nat Hum Behav (2024)
Coronary artery disease
coronary artery disease
3,711,629
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004941/ScoringFiles/PGS004941.txt.gz
PGS005091
(PGS_LDP2Auto)
PGP000684
|
Abramowitz SA
et al.
JAMA (2024)
Coronary artery disease
coronary artery disease
1,428,772
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005091/ScoringFiles/PGS005091.txt.gz
PGS005092
(PGS_prscsx)
PGP000684
|
Abramowitz SA
et al.
JAMA (2024)
Coronary artery disease
coronary artery disease
1,279,502
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005092/ScoringFiles/PGS005092.txt.gz
PGS005112
(PGS_CAD)
PGP000701
|
Loesch DP
et al.
Nat Commun (2025)
Coronary artery disease
coronary artery disease
1,106,628
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005112/ScoringFiles/PGS005112.txt.gz
PGS005143
(Coronary artery disease (PRS-CS; EAS))
PGP000704
|
Jung HU
et al.
Commun Biol (2025)
Coronary artery disease
coronary artery disease
943,274
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005143/ScoringFiles/PGS005143.txt.gz
PGS005152
(Coronary artery disease (PRS-CSx; EAS+EUR))
PGP000704
|
Jung HU
et al.
Commun Biol (2025)
Coronary artery disease
coronary artery disease
943,274
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005152/ScoringFiles/PGS005152.txt.gz
PGS005231
(GRS142_CAD)
PGP000738
|
Severance LM
et al.
JACC Cardiovasc Imaging (2021)
Coronary artery disease
coronary artery disease
142
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005231/ScoringFiles/PGS005231.txt.gz
PGS005236
(CAD_AnnoPred)
PGP000740
|
Hu J
et al.
PLoS Comput Biol (2025)
Coronary artery disease
coronary artery disease
2,994,055
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005236/ScoringFiles/PGS005236.txt.gz
PGS005293
(Jorda_CAD_MTAG-PGS_2024)
PGP000759
|
Jordà P
et al.
NPJ Genom Med (2025)
Coronary artery disease
coronary artery disease
1,003,984
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005293/ScoringFiles/PGS005293.txt.gz
PGS005294
(Jorda_CAD_MTAG-PGS_females_2024)
PGP000759
|
Jordà P
et al.
NPJ Genom Med (2025)
Coronary artery disease
coronary artery disease
1,003,984
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005294/ScoringFiles/PGS005294.txt.gz
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