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PGS Catalog
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Polygenic Scores (PGS)
Polygenic Scores (PGS)
Filter PGS by Participant Ancestry
Individuals included in:
Any Stage [G, D, E]
All Stages combined [G + D + E]
Development [G, D]
- GWAS [G]
- Score development [D]
PGS Evaluation [E]
G
- Source of Variant Associations (
G
WAS)
D
- Score
D
evelopment/Training
E
- PGS
E
valuation
List of ancestries includes:
--
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Display options:
Show European ancestry data
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Multi-ancestry data
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name
PGS Publication ID
(PGP)
Reported Trait
Mapped Trait(s)
(Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File
(FTP Link)
PGS005276
(FI_PS_EUR)
PGP000750
|
Sarnowski C
et al.
Commun Biol (2025)
Fasting insulin adjusted for BMI
BMI-adjusted fasting blood insulin measurement
1,116,555
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005276/ScoringFiles/PGS005276.txt.gz
PGS005277
(FI_PS_AFR)
PGP000750
|
Sarnowski C
et al.
Commun Biol (2025)
Fasting insulin adjusted for BMI
BMI-adjusted fasting blood insulin measurement
1,233,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005277/ScoringFiles/PGS005277.txt.gz
PGS005278
(FI_PS_AMR)
PGP000750
|
Sarnowski C
et al.
Commun Biol (2025)
Fasting insulin adjusted for BMI
BMI-adjusted fasting blood insulin measurement
1,182,208
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005278/ScoringFiles/PGS005278.txt.gz
PGS000307
(GRS12_FI)
PGP000092
|
Xie T
et al.
Circ Genom Precis Med (2020)
Fasting insulin
blood insulin amount
12
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000307/ScoringFiles/PGS000307.txt.gz
PGS000836
(F-INS)
PGP000211
|
Aly DM
et al.
Nat Genet (2021)
Fasting insulin
blood insulin amount
223
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000836/ScoringFiles/PGS000836.txt.gz
PGS001351
(MAGICTA_EUR_PGS_FI)
PGP000246
|
Chen J
et al.
Nat Genet (2021)
Fasting insulin
blood insulin amount
1,025,098
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001351/ScoringFiles/PGS001351.txt.gz
PGS003466
(LDPred2_FI)
PGP000456
|
Zhang Y
et al.
EBioMedicine (2022)
Fasting insulin
blood insulin amount
850,362
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003466/ScoringFiles/PGS003466.txt.gz
PGS000306
(GRS19_FGadjBMI)
PGP000092
|
Xie T
et al.
Circ Genom Precis Med (2020)
Fasting glucose (body mass index adjusted)
BMI-adjusted fasting blood glucose measurement
19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000306/ScoringFiles/PGS000306.txt.gz
PGS000305
(GRS31_FG)
PGP000092
|
Xie T
et al.
Circ Genom Precis Med (2020)
Fasting glucose
blood glucose amount
31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000305/ScoringFiles/PGS000305.txt.gz
PGS000838
(Fasting_Glucose)
PGP000211
|
Aly DM
et al.
Nat Genet (2021)
Fasting glucose
blood glucose amount
224
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000838/ScoringFiles/PGS000838.txt.gz
PGS001350
(MAGICTA_EUR_PGS_FG)
PGP000246
|
Chen J
et al.
Nat Genet (2021)
Fasting glucose
blood glucose amount
1,023,373
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001350/ScoringFiles/PGS001350.txt.gz
PGS019794
(TPMI_FG_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasting glucose
glucose measurement
16,095
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019794/ScoringFiles/PGS019794.txt.gz
PGS019818
(TPMI_FG_LDPred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasting glucose
glucose measurement
939,736
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019818/ScoringFiles/PGS019818.txt.gz
PGS019842
(TPMI_FG_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasting glucose
glucose measurement
983,717
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019842/ScoringFiles/PGS019842.txt.gz
PGS019866
(TPMI_FG_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasting glucose
glucose measurement
437,990
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019866/ScoringFiles/PGS019866.txt.gz
PGS019890
(TPMI_FG_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasting glucose
glucose measurement
466,322
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019890/ScoringFiles/PGS019890.txt.gz
PGS019911
(TPMI_FG_PRSmix+)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasting glucose
glucose measurement
1,071,465
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019911/ScoringFiles/PGS019911.txt.gz
PGS019712
(TPMI_728.7_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasciitis
Fasciitis
347,287
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019712/ScoringFiles/PGS019712.txt.gz
PGS019713
(TPMI_728.7_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasciitis
Fasciitis
939,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019713/ScoringFiles/PGS019713.txt.gz
PGS019714
(TPMI_728.7_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasciitis
Fasciitis
460,281
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019714/ScoringFiles/PGS019714.txt.gz
PGS019715
(TPMI_728.7_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasciitis
Fasciitis
983,805
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019715/ScoringFiles/PGS019715.txt.gz
PGS019716
(TPMI_728.7_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Fasciitis
Fasciitis
990,026
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019716/ScoringFiles/PGS019716.txt.gz
PGS001292
(GBE_FH1044)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Family history of prostate cancer
family history of prostate cancer
602
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001292/ScoringFiles/PGS001292.txt.gz
PGS001392
(GBE_FH1001)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Family history of lung cancer
family history of lung cancer
312
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001392/ScoringFiles/PGS001392.txt.gz
PGS001324
(GBE_FH1065)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Family history of high blood pressure
family history
13,862
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001324/ScoringFiles/PGS001324.txt.gz
PGS001328
(GBE_FH1220)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Family history of diabetes
family history
2,515
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001328/ScoringFiles/PGS001328.txt.gz
PGS001132
(GBE_FH1113)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Family history of chronic bronchitis/emphysema
family history
1,530
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001132/ScoringFiles/PGS001132.txt.gz
PGS001337
(GBE_FH1002)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Family history of breast cancer
family history of breast cancer
195
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001337/ScoringFiles/PGS001337.txt.gz
PGS001347
(GBE_FH1263)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Family history of Alzheimer's/dementia
family history of Alzheimer’s disease
139
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001347/ScoringFiles/PGS001347.txt.gz
PGS001916
(portability-PLR_fall_1y)
PGP000263
|
Privé F
et al.
Am J Hum Genet (2022)
Falls in the last year
fall
9,917
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001916/ScoringFiles/PGS001916.txt.gz
PGS002132
(portability-ldpred2_fall_1y)
PGP000263
|
Privé F
et al.
Am J Hum Genet (2022)
Falls in the last year
fall
826,502
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002132/ScoringFiles/PGS002132.txt.gz
PGS003330
(PRS-F8)
PGP000395
|
Valenti L
et al.
JHEP Rep (2022)
Factor VIII levels
factor VIII measurement
10
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003330/ScoringFiles/PGS003330.txt.gz
PGS005227
(F6_Frailty)
PGP000735
|
Foote IF
et al.
Nat Genet (2025)
Factor 6 (disability) of frailty
frailty measurement
1,726,064
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005227/ScoringFiles/PGS005227.txt.gz
PGS005226
(F5_Frailty)
PGP000735
|
Foote IF
et al.
Nat Genet (2025)
Factor 5 (poorer cognition) of frailty
frailty measurement
1,715,891
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005226/ScoringFiles/PGS005226.txt.gz
PGS005225
(F4_Frailty)
PGP000735
|
Foote IF
et al.
Nat Genet (2025)
Factor 4 (metabolic/respiratory problems) of frailty
frailty measurement
710,413
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005225/ScoringFiles/PGS005225.txt.gz
PGS005224
(F3_Frailty)
PGP000735
|
Foote IF
et al.
Nat Genet (2025)
Factor 3 (multimorbidity) of frailty
frailty measurement
1,588,232
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005224/ScoringFiles/PGS005224.txt.gz
PGS005223
(F2_Frailty)
PGP000735
|
Foote IF
et al.
Nat Genet (2025)
Factor 2 (unhealthy lifestyle) of frailty
frailty measurement
1,719,220
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005223/ScoringFiles/PGS005223.txt.gz
PGS005222
(F1_Frailty)
PGP000735
|
Foote IF
et al.
Nat Genet (2025)
Factor 1 (social isolation) of frailty
frailty measurement
1,727,299
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005222/ScoringFiles/PGS005222.txt.gz
PGS018996
(TPMI_352.2_Lassosum2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Facial nerve disorders CN7
facial nerve disorder
241,782
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018996/ScoringFiles/PGS018996.txt.gz
PGS018997
(TPMI_352.2_LDpred2)
PGP000835
|
Chen HH
et al.
Nature (2025)
Facial nerve disorders CN7
facial nerve disorder
939,882
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018997/ScoringFiles/PGS018997.txt.gz
PGS018998
(TPMI_352.2_MegaPRS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Facial nerve disorders CN7
facial nerve disorder
18,580
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018998/ScoringFiles/PGS018998.txt.gz
PGS018999
(TPMI_352.2_PRS-CS)
PGP000835
|
Chen HH
et al.
Nature (2025)
Facial nerve disorders CN7
facial nerve disorder
983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018999/ScoringFiles/PGS018999.txt.gz
PGS019000
(TPMI_352.2_SBayesR)
PGP000835
|
Chen HH
et al.
Nature (2025)
Facial nerve disorders CN7
facial nerve disorder
1,002,253
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019000/ScoringFiles/PGS019000.txt.gz
PGS001072
(GBE_BIN_FC20001757)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Facial aging, looking 'older than you are'
aging rate
39
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001072/ScoringFiles/PGS001072.txt.gz
PGS001071
(GBE_BIN_FC30001757)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Facial aging, looking 'about your age'
aging rate
6,782
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001071/ScoringFiles/PGS001071.txt.gz
PGS001141
(GBE_BIN_FC10001757)
PGP000244
|
Tanigawa Y
et al.
PLoS Genet (2022)
Facial ageing (looking younger than you are)
skin aging
7,676
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001141/ScoringFiles/PGS001141.txt.gz
PGS004451
(disease.F41.score)
PGP000561
|
Jung H
et al.
Commun Biol (2024)
F41 (Other anxiety disorders)
anxiety disorder
1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004451/ScoringFiles/PGS004451.txt.gz
PGS004521
(meta.F41.score)
PGP000561
|
Jung H
et al.
Commun Biol (2024)
F41 (Other anxiety disorders)
anxiety disorder
1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004521/ScoringFiles/PGS004521.txt.gz
PGS004450
(disease.F17.score)
PGP000561
|
Jung H
et al.
Commun Biol (2024)
F17 (Mental and behavioural disorders due to use of tobacco)
mental disorder
1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004450/ScoringFiles/PGS004450.txt.gz
PGS004520
(meta.F17.score)
PGP000561
|
Jung H
et al.
Commun Biol (2024)
F17 (Mental and behavioural disorders due to use of tobacco)
mental disorder
1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004520/ScoringFiles/PGS004520.txt.gz
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