Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS005276
(FI_PS_EUR)
PGP000750 |
Sarnowski C et al. Commun Biol (2025)
Fasting insulin adjusted for BMI BMI-adjusted fasting blood insulin measurement 1,116,555
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005276/ScoringFiles/PGS005276.txt.gz
PGS005277
(FI_PS_AFR)
PGP000750 |
Sarnowski C et al. Commun Biol (2025)
Fasting insulin adjusted for BMI BMI-adjusted fasting blood insulin measurement 1,233,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005277/ScoringFiles/PGS005277.txt.gz
PGS005278
(FI_PS_AMR)
PGP000750 |
Sarnowski C et al. Commun Biol (2025)
Fasting insulin adjusted for BMI BMI-adjusted fasting blood insulin measurement 1,182,208
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005278/ScoringFiles/PGS005278.txt.gz
PGS000307
(GRS12_FI)
PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
Fasting insulin blood insulin amount 12
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000307/ScoringFiles/PGS000307.txt.gz
PGS000836
(F-INS)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Fasting insulin blood insulin amount 223
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000836/ScoringFiles/PGS000836.txt.gz
PGS001351
(MAGICTA_EUR_PGS_FI)
PGP000246 |
Chen J et al. Nat Genet (2021)
Fasting insulin blood insulin amount 1,025,098
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001351/ScoringFiles/PGS001351.txt.gz
PGS003466
(LDPred2_FI)
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Fasting insulin blood insulin amount 850,362
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003466/ScoringFiles/PGS003466.txt.gz
PGS000306
(GRS19_FGadjBMI)
PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
Fasting glucose (body mass index adjusted) BMI-adjusted fasting blood glucose measurement 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000306/ScoringFiles/PGS000306.txt.gz
PGS000305
(GRS31_FG)
PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
Fasting glucose blood glucose amount 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000305/ScoringFiles/PGS000305.txt.gz
PGS000838
(Fasting_Glucose)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Fasting glucose blood glucose amount 224
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000838/ScoringFiles/PGS000838.txt.gz
PGS001350
(MAGICTA_EUR_PGS_FG)
PGP000246 |
Chen J et al. Nat Genet (2021)
Fasting glucose blood glucose amount 1,023,373
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001350/ScoringFiles/PGS001350.txt.gz
PGS019794
(TPMI_FG_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Fasting glucose glucose measurement 16,095
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019794/ScoringFiles/PGS019794.txt.gz
PGS019818
(TPMI_FG_LDPred2)
PGP000835 |
Chen HH et al. Nature (2025)
Fasting glucose glucose measurement 939,736
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019818/ScoringFiles/PGS019818.txt.gz
PGS019842
(TPMI_FG_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Fasting glucose glucose measurement 983,717
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019842/ScoringFiles/PGS019842.txt.gz
PGS019866
(TPMI_FG_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Fasting glucose glucose measurement 437,990
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019866/ScoringFiles/PGS019866.txt.gz
PGS019890
(TPMI_FG_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Fasting glucose glucose measurement 466,322
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019890/ScoringFiles/PGS019890.txt.gz
PGS019911
(TPMI_FG_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Fasting glucose glucose measurement 1,071,465
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019911/ScoringFiles/PGS019911.txt.gz
PGS019712
(TPMI_728.7_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Fasciitis Fasciitis 347,287
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019712/ScoringFiles/PGS019712.txt.gz
PGS019713
(TPMI_728.7_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Fasciitis Fasciitis 939,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019713/ScoringFiles/PGS019713.txt.gz
PGS019714
(TPMI_728.7_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Fasciitis Fasciitis 460,281
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019714/ScoringFiles/PGS019714.txt.gz
PGS019715
(TPMI_728.7_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Fasciitis Fasciitis 983,805
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019715/ScoringFiles/PGS019715.txt.gz
PGS019716
(TPMI_728.7_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Fasciitis Fasciitis 990,026
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019716/ScoringFiles/PGS019716.txt.gz
PGS001292
(GBE_FH1044)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Family history of prostate cancer family history of prostate cancer 602
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001292/ScoringFiles/PGS001292.txt.gz
PGS001392
(GBE_FH1001)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Family history of lung cancer family history of lung cancer 312
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001392/ScoringFiles/PGS001392.txt.gz
PGS001324
(GBE_FH1065)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Family history of high blood pressure family history 13,862
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001324/ScoringFiles/PGS001324.txt.gz
PGS001328
(GBE_FH1220)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Family history of diabetes family history 2,515
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001328/ScoringFiles/PGS001328.txt.gz
PGS001132
(GBE_FH1113)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Family history of chronic bronchitis/emphysema family history 1,530
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001132/ScoringFiles/PGS001132.txt.gz
PGS001337
(GBE_FH1002)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Family history of breast cancer family history of breast cancer 195
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001337/ScoringFiles/PGS001337.txt.gz
PGS001347
(GBE_FH1263)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Family history of Alzheimer's/dementia family history of Alzheimer’s disease 139
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001347/ScoringFiles/PGS001347.txt.gz
PGS001916
(portability-PLR_fall_1y)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Falls in the last year fall 9,917
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001916/ScoringFiles/PGS001916.txt.gz
PGS002132
(portability-ldpred2_fall_1y)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Falls in the last year fall 826,502
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002132/ScoringFiles/PGS002132.txt.gz
PGS003330
(PRS-F8)
PGP000395 |
Valenti L et al. JHEP Rep (2022)
Factor VIII levels factor VIII measurement 10
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003330/ScoringFiles/PGS003330.txt.gz
PGS005227
(F6_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2025)
Factor 6 (disability) of frailty frailty measurement 1,726,064
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005227/ScoringFiles/PGS005227.txt.gz
PGS005226
(F5_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2025)
Factor 5 (poorer cognition) of frailty frailty measurement 1,715,891
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005226/ScoringFiles/PGS005226.txt.gz
PGS005225
(F4_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2025)
Factor 4 (metabolic/respiratory problems) of frailty frailty measurement 710,413
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005225/ScoringFiles/PGS005225.txt.gz
PGS005224
(F3_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2025)
Factor 3 (multimorbidity) of frailty frailty measurement 1,588,232
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005224/ScoringFiles/PGS005224.txt.gz
PGS005223
(F2_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2025)
Factor 2 (unhealthy lifestyle) of frailty frailty measurement 1,719,220
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005223/ScoringFiles/PGS005223.txt.gz
PGS005222
(F1_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2025)
Factor 1 (social isolation) of frailty frailty measurement 1,727,299
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005222/ScoringFiles/PGS005222.txt.gz
PGS018996
(TPMI_352.2_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Facial nerve disorders CN7 facial nerve disorder 241,782
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018996/ScoringFiles/PGS018996.txt.gz
PGS018997
(TPMI_352.2_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Facial nerve disorders CN7 facial nerve disorder 939,882
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018997/ScoringFiles/PGS018997.txt.gz
PGS018998
(TPMI_352.2_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Facial nerve disorders CN7 facial nerve disorder 18,580
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018998/ScoringFiles/PGS018998.txt.gz
PGS018999
(TPMI_352.2_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Facial nerve disorders CN7 facial nerve disorder 983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018999/ScoringFiles/PGS018999.txt.gz
PGS019000
(TPMI_352.2_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Facial nerve disorders CN7 facial nerve disorder 1,002,253
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019000/ScoringFiles/PGS019000.txt.gz
PGS001072
(GBE_BIN_FC20001757)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Facial aging, looking 'older than you are' aging rate 39
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001072/ScoringFiles/PGS001072.txt.gz
PGS001071
(GBE_BIN_FC30001757)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Facial aging, looking 'about your age' aging rate 6,782
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001071/ScoringFiles/PGS001071.txt.gz
PGS001141
(GBE_BIN_FC10001757)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Facial ageing (looking younger than you are) skin aging 7,676
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001141/ScoringFiles/PGS001141.txt.gz
PGS004451
(disease.F41.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
F41 (Other anxiety disorders) anxiety disorder 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004451/ScoringFiles/PGS004451.txt.gz
PGS004521
(meta.F41.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
F41 (Other anxiety disorders) anxiety disorder 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004521/ScoringFiles/PGS004521.txt.gz
PGS004450
(disease.F17.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
F17 (Mental and behavioural disorders due to use of tobacco) mental disorder 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004450/ScoringFiles/PGS004450.txt.gz
PGS004520
(meta.F17.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
F17 (Mental and behavioural disorders due to use of tobacco) mental disorder 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004520/ScoringFiles/PGS004520.txt.gz