Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002294
(PRS111)
 PGP000324 |
Yang Y et al. JAMA Netw Open (2022)
 Breast cancer breast carcinoma 111
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002294/ScoringFiles/PGS002294.txt.gz
PGS002293
(PRS62_psoriasis)
 PGP000323 |
Shen M et al. J Am Acad Dermatol (2022)
 Psoriasis psoriasis 62
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002293/ScoringFiles/PGS002293.txt.gz
PGS002292
(PRS36_KC)
 PGP000321 |
He W et al. JAMA Ophthalmol (2022)
 Keratoconus keratoconus 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002292/ScoringFiles/PGS002292.txt.gz
PGS002291
(PRS12_NPC)
 PGP000320 |
He YQ et al. Nat Commun (2022)
 Nasopharyngeal carcinoma nasopharyngeal neoplasm 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002291/ScoringFiles/PGS002291.txt.gz
PGS002290
(GRS10_PUA)
 PGP000318 |
Gurung RL et al. J Clin Endocrinol Metab (2022)
 Uric acid level uric acid measurement 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002290/ScoringFiles/PGS002290.txt.gz
PGS002289
(GRS23_AD)
 PGP000316 |
Zimmerman SC et al. JAMA Netw Open (2022)
 Late-onset Alzheimer's disease late-onset Alzheimer's disease 23
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002289/ScoringFiles/PGS002289.txt.gz
PGS002288
(PRS_POP)
 PGP000314 |
Pujol-Gualdo N et al. Nat Commun (2022)
 Pelvic organ prolapse pelvic organ prolapse 3,242,959
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002288/ScoringFiles/PGS002288.txt.gz
PGS002287
(GRS_286_TG)
 PGP000313 |
Kamiza AB et al. Nat Med (2022)
 Triglyceride triglyceride measurement 286
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002287/ScoringFiles/PGS002287.txt.gz
PGS002286
(GRS_286_TC)
 PGP000313 |
Kamiza AB et al. Nat Med (2022)
 Total cholesterol total cholesterol measurement 286
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002286/ScoringFiles/PGS002286.txt.gz
PGS002285
(GRS_286_LDL)
 PGP000313 |
Kamiza AB et al. Nat Med (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 286
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002285/ScoringFiles/PGS002285.txt.gz
PGS002284
(GRS_286_HDL)
 PGP000313 |
Kamiza AB et al. Nat Med (2022)
 HDL cholesterol high density lipoprotein cholesterol measurement 286
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002284/ScoringFiles/PGS002284.txt.gz
PGS002283
(GRS15_NAFLD)
 PGP000312 |
Schnurr TM et al. Hepatol Commun (2022)
 Nonalcoholic fatty liver disease metabolic dysfunction-associated steatotic liver disease 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002283/ScoringFiles/PGS002283.txt.gz
PGS002282
(GRS68_NAFLD)
 PGP000312 |
Schnurr TM et al. Hepatol Commun (2022)
 Nonalcoholic fatty liver disease metabolic dysfunction-associated steatotic liver disease 68
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002282/ScoringFiles/PGS002282.txt.gz
PGS002281
(PRS23_MM)
 PGP000310 |
Canzian F et al. Eur J Hum Genet (2021)
 Multiple myeloma plasma cell myeloma 23
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002281/ScoringFiles/PGS002281.txt.gz
PGS002280
(GRS83_AD)
 PGP000309 |
Bellenguez C et al. Nat Genet (2022)
 Alzheimer's disease Alzheimer disease 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002280/ScoringFiles/PGS002280.txt.gz
PGS002279
(GRS22_rLVEF)
 PGP000307 |
Forrest IS et al. Eur J Heart Fail (2022)
 Reduced left ventricular ejection fraction left ventricular ejection fraction measurement 22
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002279/ScoringFiles/PGS002279.txt.gz
PGS002278
(GRS16_snLVEF)
 PGP000307 |
Forrest IS et al. Eur J Heart Fail (2022)
 Supranormal left ventricular ejection fraction left ventricular ejection fraction measurement 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002278/ScoringFiles/PGS002278.txt.gz
PGS002277
(pPS_Insulin_secretion_1)
 PGP000305 |
Siddiqui MK et al. Diabetologia (2022)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz
PGS002276
(QTc_PRS-CS)
 PGP000304 |
Nauffal V et al. Circulation (2022)
 QTc duration QT interval 1,110,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002276/ScoringFiles/PGS002276.txt.gz
PGS002275
(SBP-PRS)
 PGP000303 |
Groenland EH et al. Atherosclerosis (2022)
 Systolic blood pressure systolic blood pressure 425
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002275/ScoringFiles/PGS002275.txt.gz
PGS002274
(LDL-PRS)
 PGP000303 |
Groenland EH et al. Atherosclerosis (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 279
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002274/ScoringFiles/PGS002274.txt.gz
PGS002273
(GRS12_COVID)
 PGP000302 |
Horowitz JE et al. Nat Genet (2022)
 COVID-19 infection COVID-19 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002273/ScoringFiles/PGS002273.txt.gz
PGS002272
(GRS6_COVID)
 PGP000302 |
Horowitz JE et al. Nat Genet (2022)
 COVID-19 infection COVID-19 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002272/ScoringFiles/PGS002272.txt.gz
PGS002271
(PRS_MVP)
 PGP000301 |
Roselli C et al. Eur Heart J (2022)
 Mitral valve prolapse Mitral valve prolapse 1,097,364
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002271/ScoringFiles/PGS002271.txt.gz
PGS002270
(PRS33_LC)
 PGP000300 |
Zhang P et al. Br J Cancer (2022)
 Lung cancer lung carcinoma 33
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002270/ScoringFiles/PGS002270.txt.gz
PGS002269
(PRS47_AMD)
 PGP000299 |
Zekavat SM et al. Ophthalmology (2022)
 Age-related macular degeneration age-related macular degeneration 47
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002269/ScoringFiles/PGS002269.txt.gz
PGS002268
(PRS_csPCa)
 PGP000298 |
Song SH et al. Investig Clin Urol (2022)
 Prostate cancer prostate carcinoma 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002268/ScoringFiles/PGS002268.txt.gz
PGS002267
(PRS89_AA)
 PGP000296 |
Pirruccello JP et al. Nat Genet (2021)
 Ascending thoracic aortic diameter cardiovascular disease biomarker measurement,
aortic measurement		 89
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002267/ScoringFiles/PGS002267.txt.gz
PGS002266
(PRS_29)
 PGP000295 |
Yu Y et al. Hum Mol Genet (2022)
 Nonsyndromic cleft lip with or without cleft palate cleft lip,
Cleft palate		 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002266/ScoringFiles/PGS002266.txt.gz
PGS002265
(PRS140_CRC)
 PGP000294 |
Thomas M et al. Am J Hum Genet (2020)
 Colorectal cancer colorectal cancer 140
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002265/ScoringFiles/PGS002265.txt.gz
PGS002264
(PRS_Combined)
 PGP000293 |
Sharma S et al. Gastroenterology (2022)
 Pancreatic ductal adenocarcinoma pancreatic ductal adenocarcinoma 49
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002264/ScoringFiles/PGS002264.txt.gz
PGS002263
(PRS_UF)
 PGP000291 |
Piekos JA et al. Hum Genet (2022)
 Uterine fibroids uterine corpus leiomyoma 4,457
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002263/ScoringFiles/PGS002263.txt.gz
PGS002262
(metaPRS_CAD)
 PGP000289 |
Lu X et al. Eur Heart J (2022)
 Coronary artery disease coronary artery disorder 540
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002262/ScoringFiles/PGS002262.txt.gz
PGS002261
(PRS22_NB)
 PGP000287 |
Testori A et al. Cancer Epidemiol Biomarkers Prev (2022)
 Neuroblastoma neuroblastoma 22
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002261/ScoringFiles/PGS002261.txt.gz
PGS002260
(PRS_RA)
 PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
 Rheumatoid arthritis rheumatoid arthritis 43,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002260/ScoringFiles/PGS002260.txt.gz
PGS002259
(metaPRS_Stroke)
 PGP000285 |
Lu X et al. Neurology (2021)
 Stroke stroke disorder 534
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002259/ScoringFiles/PGS002259.txt.gz
PGS002258
(GRS901_DBP)
 PGP000283 |
Evangelou E et al. Nat Genet (2018)
 Diastolic blood pressure diastolic blood pressure 885
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002258/ScoringFiles/PGS002258.txt.gz
PGS002257
(GRS901_SBP)
 PGP000283 |
Evangelou E et al. Nat Genet (2018)
 Systolic blood pressure systolic blood pressure 884
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002257/ScoringFiles/PGS002257.txt.gz
PGS002256
(GRS4_GDM)
 PGP000282 |
Wu Q et al. Diabetol Metab Syndr (2022)
 Gestational diabetes mellitus in early pregnancy gestational diabetes 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002256/ScoringFiles/PGS002256.txt.gz
PGS002255
(PRS_measured)
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Physical activity (measured) physical activity measurement 1,140,182
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002255/ScoringFiles/PGS002255.txt.gz
PGS002254
(PRS_reported)
 PGP000280 |
Kujala UM et al. Med Sci Sports Exerc (2020)
 Physical activity (self-reported) physical activity measurement,
self-reported trait		 1,142,416
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002254/ScoringFiles/PGS002254.txt.gz
PGS002253
(Melanoma_PRS45)
 PGP000274 |
Steinberg J et al. Br J Dermatol (2021)
 Melanoma melanoma 45
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002253/ScoringFiles/PGS002253.txt.gz
PGS002252
(PRS_CRC)
 PGP000279 |
Archambault AN et al. J Natl Cancer Inst (2022)
 Colorectal cancer colorectal cancer 141
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002252/ScoringFiles/PGS002252.txt.gz
PGS002251
(PRS97_BMI)
 PGP000278 |
Dashti HS et al. BMC Med (2022)
 Body mass index (BMI) body mass index 97
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002251/ScoringFiles/PGS002251.txt.gz
PGS002250
(PRS_S4)
 PGP000277 |
Dareng EO et al. Eur J Hum Genet (2022)
 Epithelial ovarian cancer ovarian carcinoma 27,240
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002250/ScoringFiles/PGS002250.txt.gz
PGS002249
(AD_PRS_0.5)
 PGP000276 |
Lourida I et al. JAMA (2019)
 Alzheimer's disease Alzheimer disease 249,273
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002249/ScoringFiles/PGS002249.txt.gz
PGS002248
(PRSice_asthma)
 PGP000275 |
Kothalawala DM et al. J Pers Med (2022)
 Childhood asthma childhood onset asthma 105
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002248/ScoringFiles/PGS002248.txt.gz
PGS002247
(Melanoma_PRS68)
 PGP000274 |
Steinberg J et al. Br J Dermatol (2021)
 Melanoma melanoma 68
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002247/ScoringFiles/PGS002247.txt.gz
PGS002246
(Melanoma_PRS50)
 PGP000274 |
Steinberg J et al. Br J Dermatol (2021)
 Melanoma melanoma 50
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002246/ScoringFiles/PGS002246.txt.gz
PGS002245
(PGS8_LF)
 PGP000273 |
Haas ME et al. Cell Genom (2021)
 Liver fat (MRI-derived) liver fat measurement 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002245/ScoringFiles/PGS002245.txt.gz
Showing 4751 to 4800 of 6972 rows