Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004588
(PRS39_Eur)
 PGP000567 |
Jung SH et al. JAMA Netw Open (2022)
 Alzheimer's disease Alzheimer disease 39
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004588/ScoringFiles/PGS004588.txt.gz
PGS001036
(GBE_INI23004)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Epstein Barr virus nuclear antigen 1 IgG seropositivity Epstein Barr virus nuclear antigen-1 seropositivity 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001036/ScoringFiles/PGS001036.txt.gz
PGS001828
(portability-PLR_290.11)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Alzheimer's disease Alzheimer disease 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001828/ScoringFiles/PGS001828.txt.gz
PGS001835
(portability-PLR_364.5)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Corneal dystrophy corneal dystrophy 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001835/ScoringFiles/PGS001835.txt.gz
PGS002950
(ExPRSweb_Glucose_MAGIC-FastingGlucose_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Glucose blood glucose amount 38
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002950/ScoringFiles/PGS002950.txt.gz
PGS002951
(ExPRSweb_Glucose_MAGIC-FastingGlucose_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Glucose blood glucose amount 38
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002951/ScoringFiles/PGS002951.txt.gz
PGS004903
(PRS_ALL)
 PGP000633 |
Al-Janabi A et al. J Allergy Clin Immunol (2023)
 Atopic dermatitis atopic eczema 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004903/ScoringFiles/PGS004903.txt.gz
PGS000022
(T1D_GRS)
 PGP000012 |
Perry DJ et al. Sci Rep (2018)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 37
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000022/ScoringFiles/PGS000022.txt.gz
PGS000061
(GRS_LDL)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 Low-density lipoprotein (LDL) cholesterol low density lipoprotein cholesterol measurement 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000061/ScoringFiles/PGS000061.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS002750
(PRS37_THR)
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Total hip replacement total hip arthroplasty,
osteoarthritis, hip		 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002750/ScoringFiles/PGS002750.txt.gz
PGS000082
(CC_Ovary)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Ovarian cancer ovarian carcinoma 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000082/ScoringFiles/PGS000082.txt.gz
PGS000793
(CC_Ovary_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Ovarian cancer ovarian carcinoma 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000793/ScoringFiles/PGS000793.txt.gz
PGS000875
(PGS36_LDLc)
 PGP000221 |
Leal LG et al. Mol Genet Genomic Med (2020)
 LDL cholesterol low density lipoprotein cholesterol measurement 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000875/ScoringFiles/PGS000875.txt.gz
PGS001025
(GBE_HC951)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Nonrheumatic aortic valve disorders (time-to-event) aortic valve disorder 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001025/ScoringFiles/PGS001025.txt.gz
PGS001271
(GBE_HC810)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Multiple sclerosis (time-to-event) multiple sclerosis 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001271/ScoringFiles/PGS001271.txt.gz
PGS001287
(GBE_HC91)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Psoriatic arthropathy psoriatic arthritis 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001287/ScoringFiles/PGS001287.txt.gz
PGS002235
(elasticnet_VTE)
 PGP000267 |
Kolin DA et al. Sci Rep (2021)
 Venous thromboembolism venous thromboembolism 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002235/ScoringFiles/PGS002235.txt.gz
PGS002292
(PRS36_KC)
 PGP000321 |
He W et al. JAMA Ophthalmol (2022)
 Keratoconus keratoconus 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002292/ScoringFiles/PGS002292.txt.gz
PGS003394
(PRS_Stepwise)
 PGP000277 |
Dareng EO et al. Eur J Hum Genet (2022)
 Epithelial ovarian cancer ovarian carcinoma 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003394/ScoringFiles/PGS003394.txt.gz
PGS005320
(LPA_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 Lipoprotein (a) lipoprotein A measurement 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005320/ScoringFiles/PGS005320.txt.gz
PGS005322
(PRS_EC)
 PGP000768 |
Marston NA et al. Nat Med (2025)
 Coronary artery disease (Endothelial cell-related) coronary artery disorder 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005322/ScoringFiles/PGS005322.txt.gz
PGS002730
(GRSlipid_35)
 PGP000337 |
Mayerhofer E et al. Brain (2022)
 LDL lowering in response to statin low density lipoprotein cholesterol measurement,
response to statin		 35
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002730/ScoringFiles/PGS002730.txt.gz
PGS004106
(pt_clump.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 35
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004106/ScoringFiles/PGS004106.txt.gz
PGS004238
(wGRS35)
 PGP000535 |
Cheng CF et al. J Gene Med (2021)
 Cardiovascular disease cardiovascular disorder 35
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004238/ScoringFiles/PGS004238.txt.gz
PGS000859
(CKD)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Chronic kidney disease chronic kidney disease 34
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000859/ScoringFiles/PGS000859.txt.gz
PGS000021
(GRS1)
 PGP000011 |
Oram RA et al. Diabetes Care (2015)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000021/ScoringFiles/PGS000021.txt.gz
PGS000026
(PHS)
 PGP000016 |
Desikan RS et al. PLoS Med (2017)
 Alzheimer's disease Alzheimer disease 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000026/ScoringFiles/PGS000026.txt.gz
PGS000122
(2018_BMD33_GRS.FN)
 PGP000056 |
Ho-Le TP et al. J Bone Miner Res (2016)
 Bone mineral density (BMD) bone tissue density 33
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000122/ScoringFiles/PGS000122.txt.gz
PGS000341
(GRS33_SSc)
 PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
 Systemic sclerosis systemic sclerosis 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000341/ScoringFiles/PGS000341.txt.gz
PGS001827
(portability-PLR_290.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Dementia dementia 33
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001827/ScoringFiles/PGS001827.txt.gz
PGS002270
(PRS33_LC)
 PGP000300 |
Zhang P et al. Br J Cancer (2022)
 Lung cancer lung carcinoma 33
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002270/ScoringFiles/PGS002270.txt.gz
PGS002307
(PRS33_gout)
 PGP000329 |
Zhang Y et al. BMC Med (2022)
 Gout gout 33
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002307/ScoringFiles/PGS002307.txt.gz
PGS000063
(GRS_TG)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 Triglycerides triglyceride measurement 32
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000063/ScoringFiles/PGS000063.txt.gz
PGS000119
(BCC32)
 PGP000055 |
Fritsche LG et al. PLoS Genet (2019)
 Basal cell carcinoma basal cell carcinoma 32
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000119/ScoringFiles/PGS000119.txt.gz
PGS000476
(PRSWEB_PHECODE174.1_C3-BREAST-3_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000476/ScoringFiles/PGS000476.txt.gz
PGS000646
(PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Chronic lymphocytic leukemia B-cell chronic lymphocytic leukemia 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000646/ScoringFiles/PGS000646.txt.gz
PGS000647
(PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Chronic lymphocytic leukemia B-cell chronic lymphocytic leukemia 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000647/ScoringFiles/PGS000647.txt.gz
PGS000665
(GRS_32)
 PGP000125 |
Marston NA et al. Circulation (2020)
 Ischemic stroke Ischemic stroke,
stroke disorder		 32
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000665/ScoringFiles/PGS000665.txt.gz
PGS000756
(GRS3_Nar)
 PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
 Narcolepsy narcolepsy-cataplexy syndrome 32
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000756/ScoringFiles/PGS000756.txt.gz
PGS003830
(TC_SAS_CT)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003830/ScoringFiles/PGS003830.txt.gz
PGS004597
(PRS32_IS)
 PGP000576 |
Peng H et al. Nutrients (2023)
 Ischemic stroke Ischemic stroke,
stroke disorder		 32
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004597/ScoringFiles/PGS004597.txt.gz
PGS000197
(G-PROB_SpA)
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Spondyloarthroparthy spondyloarthropathy 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000197/ScoringFiles/PGS000197.txt.gz
PGS000198
(G-PROB_PsA)
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Psoriatic arthritis psoriatic arthritis 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000198/ScoringFiles/PGS000198.txt.gz
PGS000305
(GRS31_FG)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Fasting glucose blood glucose amount 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000305/ScoringFiles/PGS000305.txt.gz
PGS000573
(PRSWEB_PHECODE185_C61_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 31
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000573/ScoringFiles/PGS000573.txt.gz
PGS000599
(PRSWEB_PHECODE187.2_C3-TESTIS_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of testis testicular cancer 31
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000599/ScoringFiles/PGS000599.txt.gz
PGS000724
(PRS_Ovary)
 PGP000135 |
Jia G et al. JNCI Cancer Spectr (2020)
 Epithelial ovarian cancer ovarian carcinoma 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000724/ScoringFiles/PGS000724.txt.gz
PGS000744
(PRS_melanoma_pigment.pathway)
 PGP000151 |
Cust AE et al. J Invest Dermatol (2018)
 Melanoma melanoma 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000744/ScoringFiles/PGS000744.txt.gz
PGS000876
(PRS31_AD)
 PGP000222 |
Leonenko G et al. Ann Clin Transl Neurol (2019)
 Alzheimer's disease Alzheimer disease 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000876/ScoringFiles/PGS000876.txt.gz
Showing 4801 to 4850 of 5332 rows