Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004907
(PRS31_FT4)
 PGP000639 |
Mulder TA et al. Eur J Endocrinol (2023)
 Free thyroxine concentration thyroxine level 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004907/ScoringFiles/PGS004907.txt.gz
PGS000154
(cGRS_Colorectal)
 PGP000075 |
Shi Z et al. Cancer Med (2019)
 Colorectal cancer colorectal cancer 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000154/ScoringFiles/PGS000154.txt.gz
PGS000351
(PRS_EOC)
 PGP000117 |
Barnes DR et al. Genet Med (2020)
 Invasive epithelial ovarian cancer ovarian carcinoma 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000351/ScoringFiles/PGS000351.txt.gz
PGS000456
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000456/ScoringFiles/PGS000456.txt.gz
PGS000457
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000457/ScoringFiles/PGS000457.txt.gz
PGS000862
(DR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Diabetic Retinopathy diabetic retinopathy 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000862/ScoringFiles/PGS000862.txt.gz
PGS001136
(GBE_HC413)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hematologic disease, genetic hematologic disorder 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001136/ScoringFiles/PGS001136.txt.gz
PGS001868
(portability-PLR_654.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Rhesus isoimmunization in pregnancy Rh isoimmunization 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001868/ScoringFiles/PGS001868.txt.gz
PGS004255
(GenoBoost_rheumatoid_arthritis_0)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Rheumatoid arthritis rheumatoid arthritis 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004255/ScoringFiles/PGS004255.txt.gz
PGS004280
(GenoBoost_all-cause_dementia_0)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 All-cause dementia dementia 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004280/ScoringFiles/PGS004280.txt.gz
PGS004287
(GenoBoost_alzheimer_s_disease_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004287/ScoringFiles/PGS004287.txt.gz
PGS004322
(GRS30_IS)
 PGP000555 |
McElligott B et al. Front Cardiovasc Med (2023)
 Ischemic stroke Ischemic stroke,
stroke disorder		 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004322/ScoringFiles/PGS004322.txt.gz
PGS005115
(PGS_T2D_beta_cell)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 30
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005115/ScoringFiles/PGS005115.txt.gz
PGS000118
(MEL29)
 PGP000055 |
Fritsche LG et al. PLoS Genet (2019)
 Melanoma melanoma 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000118/ScoringFiles/PGS000118.txt.gz
PGS000199
(G-PROB_Gout)
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Gout gout 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000199/ScoringFiles/PGS000199.txt.gz
PGS000423
(PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 29
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000423/ScoringFiles/PGS000423.txt.gz
PGS000753
(PRS29_AAA)
 PGP000159 |
Klarin D et al. Circulation (2020)
 Abdominal aortic aneurysm abdominal aortic aneurysm 29
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000753/ScoringFiles/PGS000753.txt.gz
PGS002266
(PRS_29)
 PGP000295 |
Yu Y et al. Hum Mol Genet (2022)
 Nonsyndromic cleft lip with or without cleft palate cleft lip,
Cleft palate		 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002266/ScoringFiles/PGS002266.txt.gz
PGS002268
(PRS_csPCa)
 PGP000298 |
Song SH et al. Investig Clin Urol (2022)
 Prostate cancer prostate carcinoma 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002268/ScoringFiles/PGS002268.txt.gz
PGS004318
(PRS29_dementia)
 PGP000548 |
Feng J et al. BMC Geriatr (2023)
 Dementia dementia 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004318/ScoringFiles/PGS004318.txt.gz
PGS004896
(mAlb)
 PGP000623 |
Cañadas-Garre M et al. Int J Mol Sci (2023)
 Microalbuminuria Moderate albuminuria 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004896/ScoringFiles/PGS004896.txt.gz
PGS005207
(BCC_PRS)
 PGP000729 |
Gibson TM et al. Nat Med (2024)
 Basal cell carcinoma basal cell carcinoma 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005207/ScoringFiles/PGS005207.txt.gz
PGS000200
(GRS28)
 PGP000082 |
Tikkanen E et al. Arterioscler Thromb Vasc Biol (2013)
 Coronary heart disease coronary artery disorder 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000200/ScoringFiles/PGS000200.txt.gz
PGS000340
(LDL-Cpsp)
 PGP000107 |
Trinder M et al. Circ Genom Precis Med (2020)
 LDL cholesterol low density lipoprotein cholesterol measurement 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000340/ScoringFiles/PGS000340.txt.gz
PGS000452
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000452/ScoringFiles/PGS000452.txt.gz
PGS000453
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000453/ScoringFiles/PGS000453.txt.gz
PGS000455
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000455/ScoringFiles/PGS000455.txt.gz
PGS000666
(PGS_LVESVi)
 PGP000126 |
Pirruccello JP et al. Nat Commun (2020)
 Body surface area-indexed left ventricular end-systolic volume left ventricular systolic function measurement 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000666/ScoringFiles/PGS000666.txt.gz
PGS002302
(PRS28_glioma)
 PGP000328 |
Choi J et al. Int J Cancer (2020)
 Glioma glioma 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002302/ScoringFiles/PGS002302.txt.gz
PGS003403
(PRS28_LDL)
 PGP000420 |
Trinder M et al. J Am Coll Cardiol (2019)
 LDL cholesterol low density lipoprotein cholesterol measurement 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003403/ScoringFiles/PGS003403.txt.gz
PGS003412
(PRS28_melanoma)
 PGP000424 |
Olsen CM et al. Br J Dermatol (2019)
 Melanoma melanoma 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003412/ScoringFiles/PGS003412.txt.gz
PGS003441
(GRS28_AD)
 PGP000444 |
Petrican R et al. Sci Rep (2023)
 Alzheimer's disease Alzheimer disease 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003441/ScoringFiles/PGS003441.txt.gz
PGS003741
(PRS28_OC)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Ovarian cancer ovarian carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003741/ScoringFiles/PGS003741.txt.gz
PGS004897
(UACR)
 PGP000623 |
Cañadas-Garre M et al. Int J Mol Sci (2023)
 Urinary albumin-to-creatinine ratio urinary albumin to creatinine ratio 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004897/ScoringFiles/PGS004897.txt.gz
PGS000010
(GRS27)
 PGP000003 |
Mega JL et al. Lancet (2015)
 Coronary heart disease coronary artery disorder 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000010/ScoringFiles/PGS000010.txt.gz
PGS000146
(CRC_GRS_27)
 PGP000069 |
Hsu L et al. Gastroenterology (2015)
 Colorectal cancer colorectal cancer 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000146/ScoringFiles/PGS000146.txt.gz
PGS000372
(PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colorectal cancer colorectal cancer 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000372/ScoringFiles/PGS000372.txt.gz
PGS000424
(PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000424/ScoringFiles/PGS000424.txt.gz
PGS000454
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000454/ScoringFiles/PGS000454.txt.gz
PGS000649
(PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Chronic lymphocytic leukemia B-cell chronic lymphocytic leukemia 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000649/ScoringFiles/PGS000649.txt.gz
PGS000652
(PRSWEB_PHECODE204.4_C90_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Multiple myeloma plasma cell myeloma 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000652/ScoringFiles/PGS000652.txt.gz
PGS000739
(HCM_GRS)
 PGP000146 |
Harper AR et al. Nat Genet (2021)
 Hypertrophic cardiomyopathy hypertrophic cardiomyopathy 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000739/ScoringFiles/PGS000739.txt.gz
PGS000854
(T2D_BetaCell)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS002233
(PRS27_NMR)
 PGP000266 |
Chen LS et al. Pharmacogenomics (2018)
 Nicotine metabolite ratio nicotine metabolite ratio 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002233/ScoringFiles/PGS002233.txt.gz
PGS003334
(PRS_dementia)
 PGP000402 |
Chen Y et al. Arch Gerontol Geriatr (2022)
 Dementia dementia 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003334/ScoringFiles/PGS003334.txt.gz
PGS004321
(PRS27_CAD)
 PGP000554 |
Marston NA et al. Circulation (2019)
 Coronary heart disease coronary artery disorder 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004321/ScoringFiles/PGS004321.txt.gz
PGS000114
(GRS-JIA-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Juvenile Idiopathic Arthritis juvenile idiopathic arthritis 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000114/ScoringFiles/PGS000114.txt.gz
PGS000736
(PRS_QRS)
 PGP000144 |
Tadros R et al. Eur Heart J (2019)
 QRS duration QRS duration 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000736/ScoringFiles/PGS000736.txt.gz
PGS000945
(GBE_HC710)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Dementia in Alzheimer's disease (time-to-event) dementia,
Alzheimer disease		 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000945/ScoringFiles/PGS000945.txt.gz
PGS001371
(GBE_INI2976)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age diabetes diagnosed age at diagnosis,
diabetes mellitus		 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001371/ScoringFiles/PGS001371.txt.gz
Showing 4851 to 4900 of 5332 rows