Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019437
(TPMI_585.32_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 End stage renal disease stage 5 chronic kidney disease 289,757
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019437/ScoringFiles/PGS019437.txt.gz
PGS019438
(TPMI_585.32_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 End stage renal disease stage 5 chronic kidney disease 939,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019438/ScoringFiles/PGS019438.txt.gz
PGS019439
(TPMI_585.32_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 End stage renal disease stage 5 chronic kidney disease 594,737
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019439/ScoringFiles/PGS019439.txt.gz
PGS019440
(TPMI_585.32_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 End stage renal disease stage 5 chronic kidney disease 983,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019440/ScoringFiles/PGS019440.txt.gz
PGS019441
(TPMI_585.32_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 End stage renal disease stage 5 chronic kidney disease 1,019,216
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019441/ScoringFiles/PGS019441.txt.gz
PGS000236
(ESM-1)
 PGP000089 |
Folkersen L et al. Nat Metab (2020)
 Endothelial cell-specific molecule 1 (ESM-1) serum levels blood protein amount 553,240
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000236/ScoringFiles/PGS000236.txt.gz
PGS001866
(portability-PLR_615)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Endometriosis endometriosis 399
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001866/ScoringFiles/PGS001866.txt.gz
PGS002077
(portability-ldpred2_615)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Endometriosis endometriosis 534,802
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002077/ScoringFiles/PGS002077.txt.gz
PGS003447
(PRS14_endo)
 PGP000447 |
Kloeve-Mogensen K et al. Front Reprod Health (2021)
 Endometriosis endometriosis 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003447/ScoringFiles/PGS003447.txt.gz
PGS019552
(TPMI_615_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Endometriosis endometriosis 787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019552/ScoringFiles/PGS019552.txt.gz
PGS019553
(TPMI_615_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Endometriosis endometriosis 939,817
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019553/ScoringFiles/PGS019553.txt.gz
PGS019554
(TPMI_615_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Endometriosis endometriosis 28,093
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019554/ScoringFiles/PGS019554.txt.gz
PGS019555
(TPMI_615_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Endometriosis endometriosis 983,765
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019555/ScoringFiles/PGS019555.txt.gz
PGS019556
(TPMI_615_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Endometriosis endometriosis 972,671
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019556/ScoringFiles/PGS019556.txt.gz
PGS000075
(CC_Endo)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Endometrial cancer endometrial carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000075/ScoringFiles/PGS000075.txt.gz
PGS000786
(CC_Endo_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Endometrial cancer endometrial carcinoma 9
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000786/ScoringFiles/PGS000786.txt.gz
PGS002300
(PRS19_endometrial)
 PGP000328 |
Choi J et al. Int J Cancer (2020)
 Endometrial cancer endometrial cancer 19
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002300/ScoringFiles/PGS002300.txt.gz
PGS002735
(PRS19)
 PGP000344 |
Bafligil C et al. Genet Med (2022)
 Endometrial cancer endometrial carcinoma 19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002735/ScoringFiles/PGS002735.txt.gz
PGS002736
(PRS24)
 PGP000344 |
Bafligil C et al. Genet Med (2022)
 Endometrial cancer endometrial carcinoma 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002736/ScoringFiles/PGS002736.txt.gz
PGS002737
(PRS72)
 PGP000344 |
Bafligil C et al. Genet Med (2022)
 Endometrial cancer endometrial carcinoma 72
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002737/ScoringFiles/PGS002737.txt.gz
PGS004244
(PRS16_endometrium)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Endometrial cancer endometrial carcinoma 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004244/ScoringFiles/PGS004244.txt.gz
PGS002324
(disease_ENDOCRINE_DIABETES.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002324/ScoringFiles/PGS002324.txt.gz
PGS002396
(disease_ENDOCRINE_DIABETES.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 3,681
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002396/ScoringFiles/PGS002396.txt.gz
PGS002445
(disease_ENDOCRINE_DIABETES.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 15,629
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002445/ScoringFiles/PGS002445.txt.gz
PGS002494
(disease_ENDOCRINE_DIABETES.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 93,293
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002494/ScoringFiles/PGS002494.txt.gz
PGS002543
(disease_ENDOCRINE_DIABETES.P+T.1e-06)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 528
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002543/ScoringFiles/PGS002543.txt.gz
PGS002592
(disease_ENDOCRINE_DIABETES.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 187
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002592/ScoringFiles/PGS002592.txt.gz
PGS002641
(disease_ENDOCRINE_DIABETES.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 256,678
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002641/ScoringFiles/PGS002641.txt.gz
PGS002690
(disease_ENDOCRINE_DIABETES.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disorder		 905,637
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002690/ScoringFiles/PGS002690.txt.gz
PGS001326
(GBE_HC431)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Emphysema pulmonary emphysema 42
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001326/ScoringFiles/PGS001326.txt.gz
PGS019773
(TPMI_796_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Elevated prostate specific antigen PSA prostate specific antigen amount 551
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019773/ScoringFiles/PGS019773.txt.gz
PGS019774
(TPMI_796_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Elevated prostate specific antigen PSA prostate specific antigen amount 939,689
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019774/ScoringFiles/PGS019774.txt.gz
PGS019775
(TPMI_796_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Elevated prostate specific antigen PSA prostate specific antigen amount 19,808
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019775/ScoringFiles/PGS019775.txt.gz
PGS019776
(TPMI_796_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Elevated prostate specific antigen PSA prostate specific antigen amount 983,663
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019776/ScoringFiles/PGS019776.txt.gz
PGS019777
(TPMI_796_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Elevated prostate specific antigen PSA prostate specific antigen amount 1,012,264
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019777/ScoringFiles/PGS019777.txt.gz
PGS000682
(snpnet.eGFR)
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 eGFR [ml/min/1.73m2] glomerular filtration rate 17,467
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000682/ScoringFiles/PGS000682.txt.gz - Check Terms/Licenses
PGS003989
(dbslmm.auto.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 1,141,637
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003989/ScoringFiles/PGS003989.txt.gz
PGS004005
(lassosum.auto.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 15,373
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004005/ScoringFiles/PGS004005.txt.gz
PGS004017
(lassosum.CV.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 88,605
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004017/ScoringFiles/PGS004017.txt.gz
PGS004031
(ldpred2.auto.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 1,050,295
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004031/ScoringFiles/PGS004031.txt.gz
PGS004046
(ldpred2.CV.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 1,050,295
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004046/ScoringFiles/PGS004046.txt.gz
PGS004059
(megaprs.auto.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 846,995
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004059/ScoringFiles/PGS004059.txt.gz
PGS004075
(megaprs.CV.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 846,995
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004075/ScoringFiles/PGS004075.txt.gz
PGS004089
(prscs.auto.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 1,109,217
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004089/ScoringFiles/PGS004089.txt.gz
PGS004113
(pt_clump.auto.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 301
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004113/ScoringFiles/PGS004113.txt.gz
PGS004129
(pt_clump_nested.CV.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 8,543
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004129/ScoringFiles/PGS004129.txt.gz
PGS004143
(sbayesr.auto.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 804,867
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004143/ScoringFiles/PGS004143.txt.gz
PGS004159
(UKBB_EnsPGS.GCST008059.eGFR)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 eGFR glomerular filtration rate 1,141,659
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004159/ScoringFiles/PGS004159.txt.gz
PGS005318
(eGFR_PRS)
 PGP000766 |
Türkmen D et al. Pharmacogenomics J (2024)
 eGFR glomerular filtration rate 49
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005318/ScoringFiles/PGS005318.txt.gz
PGS000944
(GBE_HC261)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Eczema, dermatitis Eczematoid dermatitis,
dermatitis		 598
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000944/ScoringFiles/PGS000944.txt.gz
Showing 4901 to 4950 of 6982 rows