Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000087
(CC_Thyroid)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Thyroid cancer thyroid carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000087/ScoringFiles/PGS000087.txt.gz
PGS000070
(PRS_LC_C)
 PGP000049 |
Dai J et al. Lancet Respir Med (2019)
 Lung cancer lung adenocarcinoma 19
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000070/ScoringFiles/PGS000070.txt.gz
PGS000068
(PRS_EOC)
 PGP000048 |
Yang X et al. J Med Genet (2018)
 Epithelial ovarian cancer ovarian carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000068/ScoringFiles/PGS000068.txt.gz
PGS000069
(PRS_sEOC)
 PGP000048 |
Yang X et al. J Med Genet (2018)
 Serous epithelial ovarian cancer ovarian serous carcinoma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000069/ScoringFiles/PGS000069.txt.gz
PGS000067
(PCa_PHS)
 PGP000047 |
Seibert TM et al. BMJ (2018)
 Prostate cancer prostate carcinoma 54
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000067/ScoringFiles/PGS000067.txt.gz
PGS000064
(GLGC2017_HDL)
 PGP000046 |
Kuchenbaecker K et al. Nat Commun (2019)
 HDL cholesterol high density lipoprotein cholesterol measurement 120
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000064/ScoringFiles/PGS000064.txt.gz
PGS000065
(GLGC2017_LDL)
 PGP000046 |
Kuchenbaecker K et al. Nat Commun (2019)
 LDL cholesterol low density lipoprotein cholesterol measurement 103
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000065/ScoringFiles/PGS000065.txt.gz
PGS000066
(GLGC2017_TG)
 PGP000046 |
Kuchenbaecker K et al. Nat Commun (2019)
 Triglycerides (TG) triglyceride measurement 101
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000066/ScoringFiles/PGS000066.txt.gz
PGS000060
(GRS_HDL)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 HDL cholesterol high density lipoprotein cholesterol measurement 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000060/ScoringFiles/PGS000060.txt.gz
PGS000061
(GRS_LDL)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 Low-density lipoprotein (LDL) cholesterol low density lipoprotein cholesterol measurement 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000061/ScoringFiles/PGS000061.txt.gz
PGS000062
(GRS_TC)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 Total cholesterol total cholesterol measurement 52
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000062/ScoringFiles/PGS000062.txt.gz
PGS000063
(GRS_TG)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 Triglycerides triglyceride measurement 32
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000063/ScoringFiles/PGS000063.txt.gz
PGS000059
(CHD46)
 PGP000044 |
Hajek C et al. Circ Genom Precis Med (2018)
 Coronary heart disease coronary artery disease 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000059/ScoringFiles/PGS000059.txt.gz
PGS000058
(CAD_GRS_204)
 PGP000043 |
Morieri ML et al. Diabetes Care (2018)
 Coronary artery disease coronary artery disease 204
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000058/ScoringFiles/PGS000058.txt.gz
PGS000057
(CHD57)
 PGP000042 |
Natarajan P et al. Circulation (2017)
 Coronary heart disease coronary artery disease 57
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000057/ScoringFiles/PGS000057.txt.gz
PGS000056
(PD_PRS)
 PGP000041 |
Paul KC et al. JAMA Neurol (2018)
 Parkinson's disease Parkinson disease 23
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000056/ScoringFiles/PGS000056.txt.gz
PGS000055
(PRS_CRC)
 PGP000040 |
Schmit SL et al. J Natl Cancer Inst (2019)
 Colorectal cancer colorectal cancer 76
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000055/ScoringFiles/PGS000055.txt.gz
PGS000053
(ALZ21_NIA-LOAD)
 PGP000039 |
Tosto G et al. Neurology (2017)
 Alzheimer's disease (late onset) late-onset Alzheimer's disease 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000053/ScoringFiles/PGS000053.txt.gz
PGS000054
(ALZ21_EFIGA)
 PGP000039 |
Tosto G et al. Neurology (2017)
 Alzheimer's disease (late onset) late-onset Alzheimer's disease 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000054/ScoringFiles/PGS000054.txt.gz
PGS000052
(sPRS161)
 PGP000037 |
Lakeman IMM et al. J Med Genet (2019)
 Breast cancer breast carcinoma 161
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000052/ScoringFiles/PGS000052.txt.gz
PGS000051
(PRS67)
 PGP000036 |
Zhang X et al. PLoS Med (2018)
 Breast cancer breast carcinoma 67
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000051/ScoringFiles/PGS000051.txt.gz
PGS000050
(PRS44)
 PGP000035 |
Wen W et al. Breast Cancer Res (2016)
 Breast cancer breast carcinoma 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000050/ScoringFiles/PGS000050.txt.gz
PGS000049
(PRS103_PrCa)
 PGP000034 |
Lecarpentier J et al. J Clin Oncol (2017)
 Prostate cancer prostate carcinoma 103
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000049/ScoringFiles/PGS000049.txt.gz
PGS000045
(BCPRS_Overall)
 PGP000033 |
Kuchenbaecker KB et al. J Natl Cancer Inst (2017)
 Breast cancer breast carcinoma 88
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000045/ScoringFiles/PGS000045.txt.gz
PGS000046
(BCPRS_ER+)
 PGP000033 |
Kuchenbaecker KB et al. J Natl Cancer Inst (2017)
 Estrogen receptor [ER]-positive breast cancer estrogen-receptor positive breast cancer 87
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000046/ScoringFiles/PGS000046.txt.gz
PGS000047
(BCPRS_ER-)
 PGP000033 |
Kuchenbaecker KB et al. J Natl Cancer Inst (2017)
 Estrogen receptor [ER]-negative breast cancer estrogen-receptor negative breast cancer 53
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000047/ScoringFiles/PGS000047.txt.gz
PGS000048
(OCPRS_Overall)
 PGP000033 |
Kuchenbaecker KB et al. J Natl Cancer Inst (2017)
 Ovarian cancer ovarian carcinoma 17
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000048/ScoringFiles/PGS000048.txt.gz
PGS000044
(PrCa66)
 PGP000031 |
Pashayan N et al. Br J Cancer (2015)
 Prostate cancer prostate carcinoma 66
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000044/ScoringFiles/PGS000044.txt.gz
PGS000043
(PRS_VTE)
 PGP000030 |
Klarin D et al. Nat Genet (2019)
 Venous thromboembolism venous thromboembolism 297
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000043/ScoringFiles/PGS000043.txt.gz
PGS000041
(GRS-DQ2.5-CeD)
 PGP000029 |
Abraham G et al. Genome Med (2015)
 Coeliac disease celiac disease 2,513
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000041/ScoringFiles/PGS000041.txt.gz
PGS000042
(GRS-DQ2.5-CeD-imputed)
 PGP000029 |
Abraham G et al. Genome Med (2015)
 Coeliac disease celiac disease 3,317
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000042/ScoringFiles/PGS000042.txt.gz
PGS000040
(GRS_CeD)
 PGP000028 |
Abraham G et al. PLoS Genet (2014)
 Coeliac disease celiac disease 228
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000040/ScoringFiles/PGS000040.txt.gz
PGS000039
(metaGRS_ischaemicstroke)
 PGP000027 |
Abraham G et al. Nat Commun (2019)
 Ischemic stroke stroke,
Ischemic stroke		 3,225,583
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000039/ScoringFiles/PGS000039.txt.gz
PGS000038
(PRS90)
 PGP000026 |
Rutten-Jacobs LC et al. BMJ (2018)
 Stroke stroke 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000038/ScoringFiles/PGS000038.txt.gz
PGS000037
(PGS_AST)
 PGP000025 |
Belsky DW et al. Lancet Respir Med (2013)
 Asthma asthma 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000037/ScoringFiles/PGS000037.txt.gz
PGS000036
(gePS_T2D)
 PGP000023 |
Mahajan A et al. Nat Genet (2018)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 171,249
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000036/ScoringFiles/PGS000036.txt.gz
PGS000035
(PRS_AF)
 PGP000022 |
Weng LC et al. Circulation (2017)
 Atrial fibrillation atrial fibrillation 1,168
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000035/ScoringFiles/PGS000035.txt.gz
PGS000034
(GRS_BMI)
 PGP000021 |
Song M et al. Diabetes (2017)
 Adult body mass index (BMI) body mass index 97
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000034/ScoringFiles/PGS000034.txt.gz
PGS000031
(GRSt)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 62
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000031/ScoringFiles/PGS000031.txt.gz
PGS000032
(GRSB)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (based on SNPs involved in β-cell function) type 2 diabetes mellitus 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000032/ScoringFiles/PGS000032.txt.gz
PGS000033
(GRSIR)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (based on SNPs involved in insulin resistance) type 2 diabetes mellitus 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000033/ScoringFiles/PGS000033.txt.gz
PGS000030
(PrCa)
 PGP000019 |
Schumacher FR et al. Nat Genet (2018)
 Prostate cancer prostate carcinoma 147
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000030/ScoringFiles/PGS000030.txt.gz
PGS000028
(PRS)
 PGP000018 |
Shieh Y et al. Breast Cancer Res Treat (2016)
 Breast cancer breast carcinoma 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000028/ScoringFiles/PGS000028.txt.gz
PGS000029
(PRS_AS)
 PGP000018 |
Shieh Y et al. Breast Cancer Res Treat (2016)
 Breast cancer breast carcinoma 76
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000029/ScoringFiles/PGS000029.txt.gz
PGS000027
(GPS_BMI)
 PGP000017 |
Khera AV et al. Cell (2019)
 Body mass index (BMI) body mass index 2,100,302
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000027/ScoringFiles/PGS000027.txt.gz - Check Terms/Licenses
PGS000026
(PHS)
 PGP000016 |
Desikan RS et al. PLoS Med (2017)
 Alzheimer's disease Alzheimer disease 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000026/ScoringFiles/PGS000026.txt.gz
PGS000025
(GRS)
 PGP000015 |
Chouraki V et al. J Alzheimers Dis (2016)
 Alzheimer's disease Alzheimer disease 19
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000025/ScoringFiles/PGS000025.txt.gz
PGS000024
(GRS2)
 PGP000014 |
Sharp SA et al. Diabetes Care (2019)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 85
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000024/ScoringFiles/PGS000024.txt.gz
PGS000023
(AA_GRS)
 PGP000013 |
Onengut-Gumuscu S et al. Diabetes Care (2019)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000023/ScoringFiles/PGS000023.txt.gz
PGS000022
(T1D_GRS)
 PGP000012 |
Perry DJ et al. Sci Rep (2018)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 37
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000022/ScoringFiles/PGS000022.txt.gz
Showing 5151 to 5200 of 5221 rows