Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS018890
(TPMI_285_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other anemias anemia 953,189
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018890/ScoringFiles/PGS018890.txt.gz
PGS018891
(TPMI_290_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Delirium dementia and amnestic and other cognitive disorders cognitive disorder 21,198
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018891/ScoringFiles/PGS018891.txt.gz
PGS018892
(TPMI_290_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Delirium dementia and amnestic and other cognitive disorders cognitive disorder 939,891
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018892/ScoringFiles/PGS018892.txt.gz
PGS018893
(TPMI_290_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Delirium dementia and amnestic and other cognitive disorders cognitive disorder 16,411
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018893/ScoringFiles/PGS018893.txt.gz
PGS018894
(TPMI_290_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Delirium dementia and amnestic and other cognitive disorders cognitive disorder 983,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018894/ScoringFiles/PGS018894.txt.gz
PGS018895
(TPMI_290_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Delirium dementia and amnestic and other cognitive disorders cognitive disorder 170,479
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018895/ScoringFiles/PGS018895.txt.gz
PGS018896
(TPMI_290.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dementia dementia 56,203
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018896/ScoringFiles/PGS018896.txt.gz
PGS018897
(TPMI_290.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dementia dementia 354,947
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018897/ScoringFiles/PGS018897.txt.gz
PGS018898
(TPMI_290.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dementia dementia 14,376
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018898/ScoringFiles/PGS018898.txt.gz
PGS018899
(TPMI_290.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dementia dementia 983,826
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018899/ScoringFiles/PGS018899.txt.gz
PGS018900
(TPMI_290.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dementia dementia 84,318
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018900/ScoringFiles/PGS018900.txt.gz
PGS018901
(TPMI_290.3_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 34,357
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018901/ScoringFiles/PGS018901.txt.gz
PGS018902
(TPMI_290.3_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 939,840
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018902/ScoringFiles/PGS018902.txt.gz
PGS018903
(TPMI_290.3_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 69,993
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018903/ScoringFiles/PGS018903.txt.gz
PGS018904
(TPMI_290.3_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 983,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018904/ScoringFiles/PGS018904.txt.gz
PGS018905
(TPMI_290.3_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other persistent mental disorders due to conditions classified elsewhere mental disorder 322,143
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018905/ScoringFiles/PGS018905.txt.gz
PGS018906
(TPMI_290.11_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alzheimers disease Alzheimer disease 87
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018906/ScoringFiles/PGS018906.txt.gz
PGS018907
(TPMI_290.11_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alzheimers disease Alzheimer disease 383,714
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018907/ScoringFiles/PGS018907.txt.gz
PGS018908
(TPMI_290.11_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alzheimers disease Alzheimer disease 456,140
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018908/ScoringFiles/PGS018908.txt.gz
PGS018909
(TPMI_290.11_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alzheimers disease Alzheimer disease 983,819
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018909/ScoringFiles/PGS018909.txt.gz
PGS018910
(TPMI_290.11_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Alzheimers disease Alzheimer disease 102,677
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018910/ScoringFiles/PGS018910.txt.gz
PGS018911
(TPMI_290.13_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Senile dementia dementia 6,126
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018911/ScoringFiles/PGS018911.txt.gz
PGS018912
(TPMI_290.13_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Senile dementia dementia 939,839
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018912/ScoringFiles/PGS018912.txt.gz
PGS018913
(TPMI_290.13_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Senile dementia dementia 652,894
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018913/ScoringFiles/PGS018913.txt.gz
PGS018914
(TPMI_290.13_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Senile dementia dementia 983,791
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018914/ScoringFiles/PGS018914.txt.gz
PGS018915
(TPMI_290.13_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Senile dementia dementia 942,185
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018915/ScoringFiles/PGS018915.txt.gz
PGS018916
(TPMI_291_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other specified nonpsychotic and or transient mental disorders mental disorder 317
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018916/ScoringFiles/PGS018916.txt.gz
PGS018917
(TPMI_291_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other specified nonpsychotic and or transient mental disorders mental disorder 373,255
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018917/ScoringFiles/PGS018917.txt.gz
PGS018918
(TPMI_291_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other specified nonpsychotic and or transient mental disorders mental disorder 616,739
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018918/ScoringFiles/PGS018918.txt.gz
PGS018919
(TPMI_291_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other specified nonpsychotic and or transient mental disorders mental disorder 983,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018919/ScoringFiles/PGS018919.txt.gz
PGS018920
(TPMI_291_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other specified nonpsychotic and or transient mental disorders mental disorder 333,423
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018920/ScoringFiles/PGS018920.txt.gz
PGS018921
(TPMI_291.4_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Specific nonpsychotic mental disorders due to brain damage mental disorder 127
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018921/ScoringFiles/PGS018921.txt.gz
PGS018922
(TPMI_291.4_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Specific nonpsychotic mental disorders due to brain damage mental disorder 939,895
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018922/ScoringFiles/PGS018922.txt.gz
PGS018923
(TPMI_291.4_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Specific nonpsychotic mental disorders due to brain damage mental disorder 19,578
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018923/ScoringFiles/PGS018923.txt.gz
PGS018924
(TPMI_291.4_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Specific nonpsychotic mental disorders due to brain damage mental disorder 983,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018924/ScoringFiles/PGS018924.txt.gz
PGS018925
(TPMI_291.4_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Specific nonpsychotic mental disorders due to brain damage mental disorder 131,160
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018925/ScoringFiles/PGS018925.txt.gz
PGS018926
(TPMI_292_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neurological disorders nervous system disorder 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018926/ScoringFiles/PGS018926.txt.gz
PGS018927
(TPMI_292_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neurological disorders nervous system disorder 330,541
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018927/ScoringFiles/PGS018927.txt.gz
PGS018928
(TPMI_292_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neurological disorders nervous system disorder 566,907
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018928/ScoringFiles/PGS018928.txt.gz
PGS018929
(TPMI_292_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neurological disorders nervous system disorder 983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018929/ScoringFiles/PGS018929.txt.gz
PGS018930
(TPMI_292_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neurological disorders nervous system disorder 980,061
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018930/ScoringFiles/PGS018930.txt.gz
PGS018931
(TPMI_292.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mild cognitive impairment Cognitive impairment 37,738
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018931/ScoringFiles/PGS018931.txt.gz
PGS018932
(TPMI_292.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mild cognitive impairment Cognitive impairment 271,015
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018932/ScoringFiles/PGS018932.txt.gz
PGS018933
(TPMI_292.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mild cognitive impairment Cognitive impairment 477,076
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018933/ScoringFiles/PGS018933.txt.gz
PGS018934
(TPMI_292.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mild cognitive impairment Cognitive impairment 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018934/ScoringFiles/PGS018934.txt.gz
PGS018935
(TPMI_292.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Mild cognitive impairment Cognitive impairment 1,011,196
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018935/ScoringFiles/PGS018935.txt.gz
PGS018936
(TPMI_296.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Depression depressive disorder 230,322
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018936/ScoringFiles/PGS018936.txt.gz
PGS018937
(TPMI_296.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Depression depressive disorder 939,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018937/ScoringFiles/PGS018937.txt.gz
PGS018938
(TPMI_296.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Depression depressive disorder 18,793
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018938/ScoringFiles/PGS018938.txt.gz
PGS018939
(TPMI_296.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Depression depressive disorder 983,806
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018939/ScoringFiles/PGS018939.txt.gz
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