Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS005333
(D_MetPRS_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005333/ScoringFiles/PGS005333.txt.gz
PGS005334
(D_MetPRS_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005334/ScoringFiles/PGS005334.txt.gz
PGS005335
(D_MetPRS_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005335/ScoringFiles/PGS005335.txt.gz
PGS005336
(D_MetPRS_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005336/ScoringFiles/PGS005336.txt.gz
PGS005337
(O_MetPRS_noUKB_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005337/ScoringFiles/PGS005337.txt.gz
PGS005338
(O_MetPRS_noUKB_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005338/ScoringFiles/PGS005338.txt.gz
PGS005339
(O_MetPRS_noUKB_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005339/ScoringFiles/PGS005339.txt.gz
PGS005340
(O_MetPRS_noUKB_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005340/ScoringFiles/PGS005340.txt.gz
PGS005341
(D_MetPRS_noUKB_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005341/ScoringFiles/PGS005341.txt.gz
PGS005342
(D_MetPRS_noUKB_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005342/ScoringFiles/PGS005342.txt.gz
PGS005343
(D_MetPRS_noUKB_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005343/ScoringFiles/PGS005343.txt.gz
PGS005344
(D_MetPRS_noUKB_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005344/ScoringFiles/PGS005344.txt.gz
PGS005098
(psa2024_prs_318)
PGP000692 |
Hoffmann TJ et al. Nat Genet (2025)
Prostate specific antigen prostate specific antigen amount 318
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005098/ScoringFiles/PGS005098.txt.gz
PGS005099
(psa2024_prs_447)
PGP000692 |
Hoffmann TJ et al. Nat Genet (2025)
Prostate specific antigen prostate specific antigen amount 447
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005099/ScoringFiles/PGS005099.txt.gz
PGS005100
(psa2024_prs_disc)
PGP000692 |
Hoffmann TJ et al. Nat Genet (2025)
Prostate specific antigen prostate specific antigen amount 1,070,227
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005100/ScoringFiles/PGS005100.txt.gz
PGS005101
(psa2024_prs_joint)
PGP000692 |
Hoffmann TJ et al. Nat Genet (2025)
Prostate specific antigen prostate specific antigen amount 1,070,230
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005101/ScoringFiles/PGS005101.txt.gz
PGS005097
(prscsx_meta_HF)
PGP000691 |
Lee DSM et al. Nat Genet (2025)
Heart failure heart failure 1,274,692
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005097/ScoringFiles/PGS005097.txt.gz
PGS005096
(CAC_GRS)
PGP000689 |
Mishra PP et al. Am J Prev Cardiol (2024)
Coronary artery calcification coronary artery calcification 11
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005096/ScoringFiles/PGS005096.txt.gz
PGS005095
(WHRadjBMI_GRS)
PGP000686 |
Christiansen MR et al. Diabetes (2023)
WHR adjusted for BMI BMI-adjusted waist-hip ratio 481
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005095/ScoringFiles/PGS005095.txt.gz
PGS005093
(MetPRS)
PGP000685 |
Yang X et al. Nat Commun (2026)
Coronary artery disease coronary artery disorder 4,595
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005093/ScoringFiles/PGS005093.txt.gz
PGS005094
(ProPRS)
PGP000685 |
Yang X et al. Nat Commun (2026)
Coronary artery disease coronary artery disorder 5,249
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005094/ScoringFiles/PGS005094.txt.gz
PGS005091
(PGS_LDP2Auto)
PGP000684 |
Abramowitz SA et al. JAMA (2024)
Coronary artery disease coronary artery disorder 1,428,772
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005091/ScoringFiles/PGS005091.txt.gz
PGS005092
(PGS_prscsx)
PGP000684 |
Abramowitz SA et al. JAMA (2024)
Coronary artery disease coronary artery disorder 1,279,502
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005092/ScoringFiles/PGS005092.txt.gz
PGS005090
(CKD_PRS_AA)
PGP000683 |
Jones AC et al. J Am Soc Nephrol (2024)
Chronic kidney disease (stage 3 or higher) chronic kidney disease 1,142,436
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005090/ScoringFiles/PGS005090.txt.gz
PGS005086
(PGS64518_OC)
PGP000680 |
Barnes DR et al. NPJ Genom Med (2025)
Non-mucinous epithelial ovarian cancer ovarian carcinoma 64,518
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005086/ScoringFiles/PGS005086.txt.gz
PGS005087
(PGS5957_OC)
PGP000680 |
Barnes DR et al. NPJ Genom Med (2025)
Non-mucinous epithelial ovarian cancer ovarian carcinoma 5,957
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005087/ScoringFiles/PGS005087.txt.gz
PGS005088
(PGS3448_OC)
PGP000680 |
Barnes DR et al. NPJ Genom Med (2025)
Non-mucinous epithelial ovarian cancer ovarian carcinoma 3,448
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005088/ScoringFiles/PGS005088.txt.gz
PGS005089
(PGS400_OC)
PGP000680 |
Barnes DR et al. NPJ Genom Med (2025)
Non-mucinous epithelial ovarian cancer ovarian carcinoma 400
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005089/ScoringFiles/PGS005089.txt.gz
PGS004956
(Hemoglobin_Mean_INT_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004956/ScoringFiles/PGS004956.txt.gz
PGS004957
(Hemoglobin_Mean_INT_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004957/ScoringFiles/PGS004957.txt.gz
PGS004958
(Hemoglobin_Mean_INT_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004958/ScoringFiles/PGS004958.txt.gz
PGS004959
(Hemoglobin_Mean_INT_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004959/ScoringFiles/PGS004959.txt.gz
PGS004960
(Hemoglobin_Mean_INT_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004960/ScoringFiles/PGS004960.txt.gz
PGS004961
(Hemoglobin_Mean_INT_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004961/ScoringFiles/PGS004961.txt.gz
PGS004962
(Hemoglobin_Mean_INT_prscs_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,273,252
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004962/ScoringFiles/PGS004962.txt.gz
PGS004963
(Hemoglobin_Mean_INT_prscs_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,273,252
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004963/ScoringFiles/PGS004963.txt.gz
PGS004964
(Hemoglobin_Mean_INT_prscs_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,273,252
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004964/ScoringFiles/PGS004964.txt.gz
PGS004965
(Hemoglobin_Mean_INT_prscs_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,273,252
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004965/ScoringFiles/PGS004965.txt.gz
PGS004966
(Hemoglobin_Mean_INT_prscs_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,273,252
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004966/ScoringFiles/PGS004966.txt.gz
PGS004967
(Hemoglobin_Mean_INT_prscs_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,273,252
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004967/ScoringFiles/PGS004967.txt.gz
PGS004968
(Hemoglobin_Mean_INT_prscsx_METAweight)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,277,825
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004968/ScoringFiles/PGS004968.txt.gz
PGS004969
(LDLC_Mean_INT_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004969/ScoringFiles/PGS004969.txt.gz
PGS004970
(LDLC_Mean_INT_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004970/ScoringFiles/PGS004970.txt.gz
PGS004971
(LDLC_Mean_INT_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004971/ScoringFiles/PGS004971.txt.gz
PGS004972
(LDLC_Mean_INT_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004972/ScoringFiles/PGS004972.txt.gz
PGS004973
(LDLC_Mean_INT_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004973/ScoringFiles/PGS004973.txt.gz
PGS004974
(LDLC_Mean_INT_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004974/ScoringFiles/PGS004974.txt.gz
PGS004975
(LDLC_Mean_INT_prscs_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004975/ScoringFiles/PGS004975.txt.gz
PGS004976
(LDLC_Mean_INT_prscs_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004976/ScoringFiles/PGS004976.txt.gz
PGS004977
(LDLC_Mean_INT_prscs_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004977/ScoringFiles/PGS004977.txt.gz