Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002888
(ExPRSweb_CRP_prot-a-670_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 1,114,754
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002888/ScoringFiles/PGS002888.txt.gz
PGS003527
(cont-decay-log_CRP)
 PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre		 C-reactive protein C-reactive protein measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003527/ScoringFiles/PGS003527.txt.gz
PGS000967
(GBE_HC1221)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Coxarthrosis [arthrosis of hip] (time-to-event) osteoarthritis, hip 634
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000967/ScoringFiles/PGS000967.txt.gz
PGS002272
(GRS6_COVID)
 PGP000302 |
Horowitz JE et al. Nat Genet (2022)
 COVID-19 infection COVID-19 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002272/ScoringFiles/PGS002272.txt.gz
PGS002273
(GRS12_COVID)
 PGP000302 |
Horowitz JE et al. Nat Genet (2022)
 COVID-19 infection COVID-19 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002273/ScoringFiles/PGS002273.txt.gz
PGS019295
(TPMI_512.8_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cough Cough 137,403
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019295/ScoringFiles/PGS019295.txt.gz
PGS019296
(TPMI_512.8_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cough Cough 939,880
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019296/ScoringFiles/PGS019296.txt.gz
PGS019297
(TPMI_512.8_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cough Cough 21,473
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019297/ScoringFiles/PGS019297.txt.gz
PGS019298
(TPMI_512.8_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cough Cough 983,821
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019298/ScoringFiles/PGS019298.txt.gz
PGS019299
(TPMI_512.8_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cough Cough 943,681
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019299/ScoringFiles/PGS019299.txt.gz
PGS000834
(CIR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Corrected insulin response (at 30mins during OGTT) insulin response measurement 220
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000834/ScoringFiles/PGS000834.txt.gz
PGS003740
(PRS16_CU)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Corpus Uteri uterine corpus cancer 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003740/ScoringFiles/PGS003740.txt.gz
PGS004444
(disease.CVD.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Coronary vascular disease (CVD) coronary artery disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004444/ScoringFiles/PGS004444.txt.gz
PGS004514
(meta.CVD.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Coronary vascular disease (CVD) coronary artery disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004514/ScoringFiles/PGS004514.txt.gz
PGS000010
(GRS27)
 PGP000003 |
Mega JL et al. Lancet (2015)
 Coronary heart disease coronary artery disorder 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000010/ScoringFiles/PGS000010.txt.gz
PGS000057
(CHD57)
 PGP000042 |
Natarajan P et al. Circulation (2017)
 Coronary heart disease coronary artery disorder 57
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000057/ScoringFiles/PGS000057.txt.gz
PGS000059
(CHD46)
 PGP000044 |
Hajek C et al. Circ Genom Precis Med (2018)
 Coronary heart disease coronary artery disorder 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000059/ScoringFiles/PGS000059.txt.gz
PGS000200
(GRS28)
 PGP000082 |
Tikkanen E et al. Arterioscler Thromb Vasc Biol (2013)
 Coronary heart disease coronary artery disorder 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000200/ScoringFiles/PGS000200.txt.gz
PGS000329
(PRS_CHD)
 PGP000100 |
Mars N et al. Nat Med (2020)
 Coronary heart disease coronary artery disorder 6,423,165
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000329/ScoringFiles/PGS000329.txt.gz
PGS000798
(157SNP_GRS)
 PGP000187 |
Severance LM et al. J Cardiovasc Comput Tomogr (2019)
 Coronary heart disease coronary artery disorder 157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000798/ScoringFiles/PGS000798.txt.gz
PGS000818
(GRS_Metabo)
 PGP000202 |
Bauer A et al. Genet Epidemiol (2021)
 Coronary heart disease coronary artery disorder 138
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000818/ScoringFiles/PGS000818.txt.gz
PGS000899
(PRS176_CHD)
 PGP000232 |
Feitosa MF et al. Circ Genom Precis Med (2021)
 Coronary heart disease coronary artery disorder 176
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000899/ScoringFiles/PGS000899.txt.gz
PGS001780
(CHD_PRSCS)
 PGP000261 |
Tamlander M et al. Commun Biol (2022)
 Coronary heart disease coronary artery disorder 1,090,048
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001780/ScoringFiles/PGS001780.txt.gz
PGS004321
(PRS27_CAD)
 PGP000554 |
Marston NA et al. Circulation (2019)
 Coronary heart disease coronary artery disorder 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004321/ScoringFiles/PGS004321.txt.gz
PGS004595
(PRS_CHD)
 PGP000575 |
Oni-Orisan A et al. Clin Pharmacol Ther (2022)
 Coronary heart disease coronary artery disorder 164
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004595/ScoringFiles/PGS004595.txt.gz
PGS004596
(PRS64_CHD)
 PGP000576 |
Peng H et al. Nutrients (2023)
 Coronary heart disease coronary artery disorder 64
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004596/ScoringFiles/PGS004596.txt.gz
PGS004696
(multi_anc_hg37CSx)
 PGP000602 |
Smith JL et al. Circ Genom Precis Med (2024)
 Coronary heart disease coronary artery disorder 1,289,980
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004696/ScoringFiles/PGS004696.txt.gz
PGS004697
(eur_anc_hg37CSx)
 PGP000602 |
Smith JL et al. Circ Genom Precis Med (2024)
 Coronary heart disease coronary artery disorder 1,120,251
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004697/ScoringFiles/PGS004697.txt.gz
PGS004698
(multi_anc_hg37PT)
 PGP000602 |
Smith JL et al. Circ Genom Precis Med (2024)
 Coronary heart disease coronary artery disorder 542,218
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004698/ScoringFiles/PGS004698.txt.gz
PGS004879
(INTERVENE_MegaPRS_CHD)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Coronary heart disease coronary artery disorder 610,677
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004879/ScoringFiles/PGS004879.txt.gz
PGS004925
(PRS300_CHD)
 PGP000660 |
Kim Y et al. J Intern Med (2023)
 Coronary heart disease coronary artery disorder 300
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004925/ScoringFiles/PGS004925.txt.gz
PGS018408
(MultiPRS_coronary-heart-disease)
 PGP000826 |
Ometto S et al. Nat Commun (2026)
 Coronary heart disease coronary artery disorder 1,105,536
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018408/ScoringFiles/PGS018408.txt.gz
PGS001839
(portability-PLR_411.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Coronary atherosclerosis coronary atherosclerosis 25,425
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001839/ScoringFiles/PGS001839.txt.gz
PGS002048
(portability-ldpred2_411.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Coronary atherosclerosis coronary atherosclerosis 762,124
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002048/ScoringFiles/PGS002048.txt.gz
PGS019165
(TPMI_411.4_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 18,489
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019165/ScoringFiles/PGS019165.txt.gz
PGS019166
(TPMI_411.4_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 939,870
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019166/ScoringFiles/PGS019166.txt.gz
PGS019167
(TPMI_411.4_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 31,979
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019167/ScoringFiles/PGS019167.txt.gz
PGS019168
(TPMI_411.4_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 983,811
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019168/ScoringFiles/PGS019168.txt.gz
PGS019169
(TPMI_411.4_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Coronary atherosclerosis coronary atherosclerosis 941,902
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019169/ScoringFiles/PGS019169.txt.gz
PGS005322
(PRS_EC)
 PGP000768 |
Marston NA et al. Nat Med (2025)
 Coronary artery disease (Endothelial cell-related) coronary artery disorder 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005322/ScoringFiles/PGS005322.txt.gz
PGS004443
(disease.CAD.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Coronary artery disease (CAD) coronary artery disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004443/ScoringFiles/PGS004443.txt.gz
PGS004513
(meta.CAD.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Coronary artery disease (CAD) coronary artery disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004513/ScoringFiles/PGS004513.txt.gz
PGS004237
(CAD_PRS_LDpred_UKB_Pub1)
 PGP000532 |
Manikpurage HD et al. Circ Genom Precis Med (2021)
 Coronary Artery Disease coronary artery disorder 1,146,511
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004237/ScoringFiles/PGS004237.txt.gz
PGS000011
(GRS50)
 PGP000004 |
Tada H et al. Eur Heart J (2015)
 Coronary artery disease coronary artery disorder 50
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000011/ScoringFiles/PGS000011.txt.gz
PGS000012
(GRS49K)
 PGP000005 |
Abraham G et al. Eur Heart J (2016)
 Coronary artery disease coronary artery disorder 49,310
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000012/ScoringFiles/PGS000012.txt.gz
PGS000013
(GPS_CAD)
 PGP000006 |
Khera AV et al. Nat Genet (2018)
 Coronary artery disease coronary artery disorder 6,630,150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000013/ScoringFiles/PGS000013.txt.gz - Check Terms/Licenses
PGS000018
(metaGRS_CAD)
 PGP000007 |
Inouye M et al. J Am Coll Cardiol (2018)
 Coronary artery disease coronary artery disorder 1,745,179
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000018/ScoringFiles/PGS000018.txt.gz
PGS000019
(GRS_CAD)
 PGP000009 |
Paquette M et al. J Clin Lipidol (2017)
 Coronary artery disease coronary artery disorder 192
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000019/ScoringFiles/PGS000019.txt.gz
PGS000058
(CAD_GRS_204)
 PGP000043 |
Morieri ML et al. Diabetes Care (2018)
 Coronary artery disease coronary artery disorder 204
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000058/ScoringFiles/PGS000058.txt.gz
PGS000116
(CAD_EJ2020)
 PGP000054 |
Elliott J et al. JAMA (2020)
 Coronary artery disease coronary artery disorder 40,079
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000116/ScoringFiles/PGS000116.txt.gz - Check Terms/Licenses
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