Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS005356
(DPRISM_T2DPRS_trainedforAFR_EURweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,333,977
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005356/ScoringFiles/PGS005356.txt.gz
PGS005377
(DPRISM_T2DPRS_trainedforSAS_SASweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,327,177
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005377/ScoringFiles/PGS005377.txt.gz
PGS005358
(DPRISM_T2DPRS_trainedforAMR_AFRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,322,950
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005358/ScoringFiles/PGS005358.txt.gz
PGS005170
(iPRS_DEM)
PGP000718 |
D'Aoust T et al. Alzheimers Dement (2025)
All-cause dementia dementia 1,320,229
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005170/ScoringFiles/PGS005170.txt.gz
PGS005368
(DPRISM_T2DPRS_trainedforEUR_AFRweights)
PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,298,374
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005368/ScoringFiles/PGS005368.txt.gz
PGS005102
(O_MetPRS_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005102/ScoringFiles/PGS005102.txt.gz
PGS005103
(O_MetPRS_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005103/ScoringFiles/PGS005103.txt.gz
PGS005331
(O_MetPRS_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005331/ScoringFiles/PGS005331.txt.gz
PGS005332
(O_MetPRS_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005332/ScoringFiles/PGS005332.txt.gz
PGS005333
(D_MetPRS_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005333/ScoringFiles/PGS005333.txt.gz
PGS005334
(D_MetPRS_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005334/ScoringFiles/PGS005334.txt.gz
PGS005335
(D_MetPRS_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005335/ScoringFiles/PGS005335.txt.gz
PGS005336
(D_MetPRS_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005336/ScoringFiles/PGS005336.txt.gz
PGS005337
(O_MetPRS_noUKB_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005337/ScoringFiles/PGS005337.txt.gz
PGS005338
(O_MetPRS_noUKB_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005338/ScoringFiles/PGS005338.txt.gz
PGS005339
(O_MetPRS_noUKB_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005339/ScoringFiles/PGS005339.txt.gz
PGS005340
(O_MetPRS_noUKB_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Body mass index (BMI) body mass index 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005340/ScoringFiles/PGS005340.txt.gz
PGS005341
(D_MetPRS_noUKB_AFR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005341/ScoringFiles/PGS005341.txt.gz
PGS005342
(D_MetPRS_noUKB_EAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005342/ScoringFiles/PGS005342.txt.gz
PGS005343
(D_MetPRS_noUKB_EUR)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005343/ScoringFiles/PGS005343.txt.gz
PGS005344
(D_MetPRS_noUKB_SAS)
PGP000693 |
Kim MS et al. Cell Metab (2026)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,297,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005344/ScoringFiles/PGS005344.txt.gz
PGS005217
(PRS_PAD)
PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
Peripheral artery disease peripheral arterial disease 1,296,292
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005217/ScoringFiles/PGS005217.txt.gz
PGS005199
(G23_BMI_2025_PRSCSx_META)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,296,245
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005199/ScoringFiles/PGS005199.txt.gz - Check Terms/Licenses
PGS003725
(GPS_Mult)
PGP000466 |
Patel AP et al. Nat Med (2023)
Coronary artery disease coronary artery disorder 1,296,172
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003725/ScoringFiles/PGS003725.txt.gz
PGS003726
(GPS_CADANC)
PGP000466 |
Patel AP et al. Nat Med (2023)
Coronary artery disease coronary artery disorder 1,296,172
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003726/ScoringFiles/PGS003726.txt.gz
PGS002969
(ExPRSweb_Height_50-raw_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Height body height 1,296,068
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002969/ScoringFiles/PGS002969.txt.gz
PGS002964
(ExPRSweb_Height_50-irnt_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Height body height 1,291,379
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002964/ScoringFiles/PGS002964.txt.gz
PGS004696
(multi_anc_hg37CSx)
PGP000602 |
Smith JL et al. Circ Genom Precis Med (2024)
Coronary heart disease coronary artery disorder 1,289,980
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004696/ScoringFiles/PGS004696.txt.gz
PGS004956
(Hemoglobin_Mean_INT_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004956/ScoringFiles/PGS004956.txt.gz
PGS004957
(Hemoglobin_Mean_INT_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004957/ScoringFiles/PGS004957.txt.gz
PGS004958
(Hemoglobin_Mean_INT_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004958/ScoringFiles/PGS004958.txt.gz
PGS004959
(Hemoglobin_Mean_INT_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004959/ScoringFiles/PGS004959.txt.gz
PGS004960
(Hemoglobin_Mean_INT_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004960/ScoringFiles/PGS004960.txt.gz
PGS004961
(Hemoglobin_Mean_INT_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Hemoglobin hemoglobin measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004961/ScoringFiles/PGS004961.txt.gz
PGS004969
(LDLC_Mean_INT_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004969/ScoringFiles/PGS004969.txt.gz
PGS004970
(LDLC_Mean_INT_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004970/ScoringFiles/PGS004970.txt.gz
PGS004971
(LDLC_Mean_INT_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004971/ScoringFiles/PGS004971.txt.gz
PGS004972
(LDLC_Mean_INT_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004972/ScoringFiles/PGS004972.txt.gz
PGS004973
(LDLC_Mean_INT_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004973/ScoringFiles/PGS004973.txt.gz
PGS004974
(LDLC_Mean_INT_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
LDL cholesterol low density lipoprotein cholesterol measurement 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004974/ScoringFiles/PGS004974.txt.gz
PGS004982
(mean_BMI_INT_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Body mass index (BMI) body mass index 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004982/ScoringFiles/PGS004982.txt.gz
PGS004983
(mean_BMI_INT_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Body mass index (BMI) body mass index 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004983/ScoringFiles/PGS004983.txt.gz
PGS004984
(mean_BMI_INT_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Body mass index (BMI) body mass index 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004984/ScoringFiles/PGS004984.txt.gz
PGS004985
(mean_BMI_INT_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Body mass index (BMI) body mass index 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004985/ScoringFiles/PGS004985.txt.gz
PGS004986
(mean_BMI_INT_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Body mass index (BMI) body mass index 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004986/ScoringFiles/PGS004986.txt.gz
PGS004987
(mean_BMI_INT_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Body mass index (BMI) body mass index 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004987/ScoringFiles/PGS004987.txt.gz
PGS004995
(mean_Height_INT_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Height body height 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004995/ScoringFiles/PGS004995.txt.gz
PGS004996
(mean_Height_INT_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Height body height 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004996/ScoringFiles/PGS004996.txt.gz
PGS004997
(mean_Height_INT_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Height body height 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004997/ScoringFiles/PGS004997.txt.gz
PGS004998
(mean_Height_INT_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Height body height 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004998/ScoringFiles/PGS004998.txt.gz