Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019579
(TPMI_686.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Carbuncle and furuncle carbuncle,
Furuncle		 15,269
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019579/ScoringFiles/PGS019579.txt.gz
PGS019789
(TPMI_ALT_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Serum glutamate pyruvate transaminase serum alanine aminotransferase amount 15,260
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019789/ScoringFiles/PGS019789.txt.gz
PGS001912
(portability-PLR_F_age_first_birth)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age at first live birth age at first birth measurement 15,201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001912/ScoringFiles/PGS001912.txt.gz
PGS001414
(GBE_INI30180)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Lymphocyte % lymphocyte percentage of leukocytes 15,143
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001414/ScoringFiles/PGS001414.txt.gz
PGS001180
(GBE_INI1003063)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Lung function (FEV1/FVC) FEV/FVC ratio 15,141
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001180/ScoringFiles/PGS001180.txt.gz
PGS002401
(biochemistry_HDLcholesterol.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 HDL cholesterol high density lipoprotein cholesterol measurement 15,141
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002401/ScoringFiles/PGS002401.txt.gz
PGS001010
(GBE_INI1003064)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 PEF pred. ratio peak expiratory flow 15,135
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001010/ScoringFiles/PGS001010.txt.gz
PGS001243
(GBE_INI4119)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ankle spacing width (R) anthropometric measurement 15,134
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001243/ScoringFiles/PGS001243.txt.gz
PGS004934
(hypertension_snpnet_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Hypertension hypertensive disorder 15,056
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004934/ScoringFiles/PGS004934.txt.gz
PGS002410
(blood_LYMPHOCYTE_COUNT.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Lymphocyte count lymphocyte count 14,889
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002410/ScoringFiles/PGS002410.txt.gz
PGS019202
(TPMI_427.5_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Arrhythmia cardiac NOS cardiac arrhythmia 14,836
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019202/ScoringFiles/PGS019202.txt.gz
PGS019098
(TPMI_386.3_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Labyrinthitis labyrinthitis 14,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019098/ScoringFiles/PGS019098.txt.gz
PGS001952
(portability-PLR_log_glucose)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Glucose glucose measurement 14,811
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001952/ScoringFiles/PGS001952.txt.gz
PGS003045
(ExPRSweb_Smoking_20116-1_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Smoking status smoking status measurement 14,682
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003045/ScoringFiles/PGS003045.txt.gz
PGS000685
(snpnet.Glycated_haemoglobin_HbA1c)
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 HbA1c [mmol/mol] HbA1c measurement 14,658
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000685/ScoringFiles/PGS000685.txt.gz - Check Terms/Licenses
PGS002468
(disease_RESPIRATORY_ENT.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Respiratory and ear-nose-throat diseases respiratory system disorder 14,628
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002468/ScoringFiles/PGS002468.txt.gz
PGS002441
(disease_DERMATOLOGY.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Dermatologic diseases skin disorder 14,624
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002441/ScoringFiles/PGS002441.txt.gz
PGS003683
(R_molecular_layer_HP_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right molecular layer hippocampus proper head volume hippocampus molecular layer volume 14,560
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003683/ScoringFiles/PGS003683.txt.gz
PGS001233
(GBE_INI102)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heart rate (AR) heart rate 14,455
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001233/ScoringFiles/PGS001233.txt.gz
PGS019719
(TPMI_729.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Rheumatism unspecified and fibrositis rheumatic disorder 14,417
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019719/ScoringFiles/PGS019719.txt.gz
PGS002608
(blood_MEAN_PLATELET_VOL.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Mean platelet volume platelet volume 14,380
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002608/ScoringFiles/PGS002608.txt.gz
PGS018898
(TPMI_290.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dementia dementia 14,376
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018898/ScoringFiles/PGS018898.txt.gz
PGS000952
(GBE_INI3147)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel quantitative ultrasound index (QUI), direct entry bone quantitative ultrasound measurement 14,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000952/ScoringFiles/PGS000952.txt.gz
PGS001037
(GBE_INI78)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel bone mineral density (BMD) T-score, automated heel bone mineral density 14,310
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001037/ScoringFiles/PGS001037.txt.gz
PGS001402
(GBE_INI3148)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel bone mineral density (BMD) heel bone mineral density 14,251
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001402/ScoringFiles/PGS001402.txt.gz
PGS019387
(TPMI_574.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cholelithiasis cholelithiasis 14,247
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019387/ScoringFiles/PGS019387.txt.gz
PGS003626
(L_CA3_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 head volume hippocampal CA3 volume 14,199
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003626/ScoringFiles/PGS003626.txt.gz
PGS003056
(ExPRSweb_Smoking_20160_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Smoking status smoking status measurement 14,184
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003056/ScoringFiles/PGS003056.txt.gz
PGS003958
(AD_Unweighted_PRSsum)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 14,109
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003958/ScoringFiles/PGS003958.txt.gz
PGS001133
(GBE_INI4079)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Diastolic BP (AR) diastolic blood pressure 14,103
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001133/ScoringFiles/PGS001133.txt.gz
PGS003622
(L_CA3_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left CA3 head volume hippocampal CA3 volume 14,099
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003622/ScoringFiles/PGS003622.txt.gz
PGS001335
(GBE_BIN_FC4006150)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Vascular/heart problems diagnosed by doctor High BP cardiovascular disorder 14,076
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001335/ScoringFiles/PGS001335.txt.gz
PGS004194
(hyper_4)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Hypertension hypertensive disorder 14,063
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004194/ScoringFiles/PGS004194.txt.gz
PGS003680
(R_fimbria_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right fimbria volume hippocampus fimbria volume 13,970
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003680/ScoringFiles/PGS003680.txt.gz
PGS002429
(blood_WHITE_COUNT.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 White blood cell count leukocyte quantity 13,898
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002429/ScoringFiles/PGS002429.txt.gz
PGS001324
(GBE_FH1065)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Family history of high blood pressure family history 13,862
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001324/ScoringFiles/PGS001324.txt.gz
PGS001851
(portability-PLR_530.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Esophagitis, GERD and related diseases esophagitis,
gastroesophageal reflux disease		 13,855
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001851/ScoringFiles/PGS001851.txt.gz
PGS002816
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 13,852
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002816/ScoringFiles/PGS002816.txt.gz
PGS002817
(ExPRSweb_AgeAtMenarche_ieu-a-1095_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menarche age at menarche 13,852
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002817/ScoringFiles/PGS002817.txt.gz
PGS001830
(portability-PLR_318)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Tobacco use disorder nicotine dependence 13,838
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001830/ScoringFiles/PGS001830.txt.gz
PGS001320
(GBE_HC215)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hypertension hypertensive disorder 13,791
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001320/ScoringFiles/PGS001320.txt.gz
PGS002455
(disease_HI_CHOL_SELF_REP.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 High cholesterol Hypercholesterolemia 13,788
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002455/ScoringFiles/PGS002455.txt.gz
PGS001239
(GBE_INI30000)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 White blood cell count leukocyte quantity 13,785
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001239/ScoringFiles/PGS001239.txt.gz
PGS001119
(GBE_INI46)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Left hand grip strength grip strength measurement 13,767
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001119/ScoringFiles/PGS001119.txt.gz
PGS000951
(GBE_INI3144)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Heel Broadband ultrasound attenuation, direct entry bone quantitative ultrasound measurement 13,735
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000951/ScoringFiles/PGS000951.txt.gz
PGS001077
(GBE_INI30200)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Neutrophil percentage neutrophil percentage of leukocytes 13,703
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001077/ScoringFiles/PGS001077.txt.gz
PGS003146
(ExPRSweb_TG_30870-irnt_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Triglycerides triglyceride measurement 13,680
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003146/ScoringFiles/PGS003146.txt.gz
PGS003085
(ExPRSweb_SBP_93-raw_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Systolic blood pressure systolic blood pressure 13,447
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003085/ScoringFiles/PGS003085.txt.gz
PGS003435
(CT)
 PGP000438 |
Briggs SEW et al. BMJ (2022)
 Colorectal cancer colorectal cancer 13,446
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003435/ScoringFiles/PGS003435.txt.gz
PGS001242
(GBE_INI4100)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ankle spacing width (L) anthropometric measurement 13,416
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001242/ScoringFiles/PGS001242.txt.gz
Showing 4301 to 4350 of 6972 rows