Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS004929
(AF_Ldpred2_combined)
PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
Atrial fibrillation atrial fibrillation 178,814
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004929/ScoringFiles/PGS004929.txt.gz
PGS005159
(GRS142_AF)
PGP000709 |
Frederiksen TC et al. Heart (2024)
Atrial fibrillation atrial fibrillation 142
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005159/ScoringFiles/PGS005159.txt.gz
PGS005168
(PRSAF)
PGP000712 |
Roselli C et al. Nat Genet (2025)
Atrial fibrillation atrial fibrillation 382,963
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005168/ScoringFiles/PGS005168.txt.gz
PGS005171
(PRS142_AF)
PGP000719 |
Dai L et al. Diabetes Metab Syndr (2024)
Atrial fibrillation atrial fibrillation 142
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005171/ScoringFiles/PGS005171.txt.gz
PGS005287
(Jorda_AF_MTAG-PGS_2024)
PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
Atrial fibrillation atrial fibrillation 1,016,634
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005287/ScoringFiles/PGS005287.txt.gz
PGS005288
(Jorda_AF_MTAG-PGS_females_2024)
PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
Atrial fibrillation atrial fibrillation 1,016,634
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005288/ScoringFiles/PGS005288.txt.gz
PGS005289
(Jorda_AF_MTAG-PGS_males_2024)
PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
Atrial fibrillation atrial fibrillation 1,016,634
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005289/ScoringFiles/PGS005289.txt.gz
PGS005290
(Jorda_AF_SingleTrait-PGS_2024)
PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
Atrial fibrillation atrial fibrillation 1,045,170
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005290/ScoringFiles/PGS005290.txt.gz
PGS005291
(Jorda_AF_SingleTrait-PGS_females_2024)
PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
Atrial fibrillation atrial fibrillation 1,045,170
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005291/ScoringFiles/PGS005291.txt.gz
PGS005292
(Jorda_AF_SingleTrait-PGS_males_2024)
PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
Atrial fibrillation atrial fibrillation 1,045,170
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005292/ScoringFiles/PGS005292.txt.gz
PGS005313
(AF_PGS_YuanS)
PGP000761 |
Yuan S et al. Nat Commun (2025)
Atrial fibrillation atrial fibrillation 1,271,239
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005313/ScoringFiles/PGS005313.txt.gz
PGS012531
(ALLmeta)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,514
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012531/ScoringFiles/PGS012531.txt.gz
PGS012532
(Mult-t-EUR)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012532/ScoringFiles/PGS012532.txt.gz
PGS012533
(Mult-t-AMR)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012533/ScoringFiles/PGS012533.txt.gz
PGS012534
(Mult-t-AFR)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012534/ScoringFiles/PGS012534.txt.gz
PGS012535
(Mult-t-SAS)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012535/ScoringFiles/PGS012535.txt.gz
PGS012536
(Mult-t-EAS)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,461
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012536/ScoringFiles/PGS012536.txt.gz
PGS012537
(UKB_Mult-t-AFR)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,497
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012537/ScoringFiles/PGS012537.txt.gz
PGS012538
(UKB_Mult-t-SAS)
PGP000788 |
Haydarlou P et al. Nat Commun (2026)
Atrial fibrillation atrial fibrillation 7,356,497
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012538/ScoringFiles/PGS012538.txt.gz
PGS012577
(GRS134_AF)
PGP000812 |
Chen Y et al. Eur J Psychotraumatol (2024)
Atrial fibrillation atrial fibrillation 134
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012577/ScoringFiles/PGS012577.txt.gz
PGS012580
(PRS25_AF)
PGP000814 |
Zheng J et al. J Intern Med (2024)
Atrial fibrillation atrial fibrillation 25
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012580/ScoringFiles/PGS012580.txt.gz
PGS004705
(afib_PRSmix_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Atrial Fibrillation atrial fibrillation 3,575,124
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004705/ScoringFiles/PGS004705.txt.gz
PGS004706
(afib_PRSmixPlus_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Atrial Fibrillation atrial fibrillation 3,576,958
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004706/ScoringFiles/PGS004706.txt.gz
PGS001841
(portability-PLR_427.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Atrial fibrillation and flutter atrial fibrillation,
atrial flutter
3,980
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001841/ScoringFiles/PGS001841.txt.gz
PGS002050
(portability-ldpred2_427.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Atrial fibrillation and flutter atrial fibrillation,
atrial flutter
554,908
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002050/ScoringFiles/PGS002050.txt.gz
PGS001339
(GBE_HC964)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Atrial fibrillation and flutter (time-to-event) atrial fibrillation,
atrial flutter
2,142
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001339/ScoringFiles/PGS001339.txt.gz
PGS005060
(Phe_427_21_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005060/ScoringFiles/PGS005060.txt.gz
PGS005061
(Phe_427_21_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005061/ScoringFiles/PGS005061.txt.gz
PGS005062
(Phe_427_21_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005062/ScoringFiles/PGS005062.txt.gz
PGS005063
(Phe_427_21_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005063/ScoringFiles/PGS005063.txt.gz
PGS005064
(Phe_427_21_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005064/ScoringFiles/PGS005064.txt.gz
PGS005065
(Phe_427_21_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005065/ScoringFiles/PGS005065.txt.gz
PGS005066
(Phe_427_21_prscs_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005066/ScoringFiles/PGS005066.txt.gz
PGS005067
(Phe_427_21_prscs_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005067/ScoringFiles/PGS005067.txt.gz
PGS005068
(Phe_427_21_prscs_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005068/ScoringFiles/PGS005068.txt.gz
PGS005069
(Phe_427_21_prscs_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005069/ScoringFiles/PGS005069.txt.gz
PGS005070
(Phe_427_21_prscs_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005070/ScoringFiles/PGS005070.txt.gz
PGS005071
(Phe_427_21_prscs_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005071/ScoringFiles/PGS005071.txt.gz
PGS005072
(Phe_427_21_prscsx_METAweight)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Atrial fibrillation (PheCode 427.21) atrial fibrillation 1,273,891
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005072/ScoringFiles/PGS005072.txt.gz
PGS001263
(GBE_HC440)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Atrial flutter atrial flutter 2,087
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001263/ScoringFiles/PGS001263.txt.gz
PGS001018
(GBE_BIN_FC10006160)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Attending social / leisure activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) social interaction measurement 2,912
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001018/ScoringFiles/PGS001018.txt.gz
PGS001019
(GBE_BIN_FC20006160)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Attending social / leisure activities (regular attendance at a gym or sports club) social interaction measurement 11,361
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001019/ScoringFiles/PGS001019.txt.gz
PGS001020
(GBE_BIN_FC50006160)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Attending social / leisure activities (regular attendance at an adult education class) social interaction measurement 220
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001020/ScoringFiles/PGS001020.txt.gz
PGS003753
(PRS35445_ADHD)
PGP000473 |
Sato JR et al. Genes Brain Behav (2023)
Attention deficit hyperactivity disorder attention deficit-hyperactivity disorder 35,445
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003753/ScoringFiles/PGS003753.txt.gz
PGS002746
(PRS_ADHD)
PGP000358 |
Lahey BB et al. J Psychiatr Res (2022)
Attention-deficit hyperactivity disorder attention deficit-hyperactivity disorder 513,659
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002746/ScoringFiles/PGS002746.txt.gz
PGS000327
(ASD2019)
PGP000098 |
Grove J et al. Nat Genet (2019)
Autism spectrum disorder autism spectrum disorder 35,087
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000327/ScoringFiles/PGS000327.txt.gz
PGS002790
(ASD_SDPR)
PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
Autism spectrum disorder autism spectrum disorder 916,713
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002790/ScoringFiles/PGS002790.txt.gz
PGS004239
(PRS14AAD)
PGP000538 |
Aranda-Guillén M et al. J Intern Med (2023)
Autoimmune Addison's disease chronic primary adrenal insufficiency 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004239/ScoringFiles/PGS004239.txt.gz
PGS002312
(disease_AID_ALL.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Autoimmune disease autoimmune disease 1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002312/ScoringFiles/PGS002312.txt.gz
PGS002359
(disease_AID_ALL.BOLT-LMM-BBJ)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Autoimmune disease autoimmune disease 920,927
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002359/ScoringFiles/PGS002359.txt.gz