Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004223
(PRS139_T2D)
 PGP000523 |
Lin J et al. Sci Total Environ (2023)
 Type 2 diabetes type 2 diabetes mellitus 139
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004223/ScoringFiles/PGS004223.txt.gz
PGS004225
(PRS46_T2DEastAsia)
 PGP000526 |
Liu J et al. Nutrients (2023)
 Type 2 diabetes type 2 diabetes mellitus 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004225/ScoringFiles/PGS004225.txt.gz
PGS004226
(PRS50_T2DEur)
 PGP000526 |
Liu J et al. Nutrients (2023)
 Type 2 diabetes type 2 diabetes mellitus 50
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004226/ScoringFiles/PGS004226.txt.gz
PGS004323
(PRS91_T2D)
 PGP000557 |
Tan Q et al. J Hazard Mater (2023)
 Type 2 diabetes type 2 diabetes mellitus 91
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004323/ScoringFiles/PGS004323.txt.gz
PGS000848
(T2D_Adiposity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with adiposity) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz
PGS000854
(T2D_BetaCell)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS000849
(T2D_Impaired_Lipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with impaired lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000849/ScoringFiles/PGS000849.txt.gz
PGS000850
(T2D_Insulin_Action)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS000853
(T2D_Insulin_Secretion_2)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz
PGS002277
(pPS_Insulin_secretion_1)
 PGP000305 |
Siddiqui MK et al. Diabetologia (2022)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz
PGS000855
(T2D_Lipodystrophy)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with lipodystrophy) type 2 diabetes mellitus 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz
PGS000856
(T2D_LiverLipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with liver lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000856/ScoringFiles/PGS000856.txt.gz
PGS000857
(T2D_Obesity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with obesity) type 2 diabetes mellitus 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000857/ScoringFiles/PGS000857.txt.gz
PGS000858
(T2D_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with proinsulin levels) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz
PGS000033
(GRSIR)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (based on SNPs involved in insulin resistance) type 2 diabetes mellitus 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000033/ScoringFiles/PGS000033.txt.gz
PGS000032
(GRSB)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (based on SNPs involved in β-cell function) type 2 diabetes mellitus 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000032/ScoringFiles/PGS000032.txt.gz
PGS012547
(EN_model_T2D)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Type 2 diabetes mellitus type 2 diabetes mellitus 969,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012547/ScoringFiles/PGS012547.txt.gz
PGS005324
(T2D_PRS_weighted)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,279,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005324/ScoringFiles/PGS005324.txt.gz
PGS005325
(T2D_PRS_unweighted)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,279,733
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005325/ScoringFiles/PGS005325.txt.gz
PGS005326
(T2D_PRS_AFR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,214,634
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005326/ScoringFiles/PGS005326.txt.gz
PGS005327
(T2D_PRS_AMR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 972,776
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005327/ScoringFiles/PGS005327.txt.gz
PGS005328
(T2D_PRS_EAS)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 570,349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005328/ScoringFiles/PGS005328.txt.gz
PGS005329
(T2D_PRS_EUR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 1,112,468
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005329/ScoringFiles/PGS005329.txt.gz
PGS005330
(T2D_PRS_SAS)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 642,349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005330/ScoringFiles/PGS005330.txt.gz
PGS000014
(GPS_T2D)
 PGP000006 |
Khera AV et al. Nat Genet (2018)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,917,436
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000014/ScoringFiles/PGS000014.txt.gz - Check Terms/Licenses
PGS000020
(dGRS1000)
 PGP000010 |
Läll K et al. Genet Med (2016)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 7,502
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000020/ScoringFiles/PGS000020.txt.gz
PGS000031
(GRSt)
 PGP000020 |
Vassy JL et al. Diabetes (2014)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 62
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000031/ScoringFiles/PGS000031.txt.gz
PGS000036
(gePS_T2D)
 PGP000023 |
Mahajan A et al. Nat Genet (2018)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 171,249
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000036/ScoringFiles/PGS000036.txt.gz
PGS000125
(Qi_T2D_2017)
 PGP000062 |
Qi Q et al. Diabetes (2017)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 80
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000125/ScoringFiles/PGS000125.txt.gz
PGS000330
(PRS_T2D)
 PGP000100 |
Mars N et al. Nat Med (2020)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,437,380
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000330/ScoringFiles/PGS000330.txt.gz
PGS000713
(T2D)
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 183,830
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000713/ScoringFiles/PGS000713.txt.gz - Check Terms/Licenses
PGS000729
(T2D_PGS)
 PGP000137 |
Ritchie SC et al. Nat Metab (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 2,017,388
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000729/ScoringFiles/PGS000729.txt.gz
PGS000804
(GRS582_T2Dmulti)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000804/ScoringFiles/PGS000804.txt.gz - Check Terms/Licenses
PGS000805
(GRS582_T2Deur)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000805/ScoringFiles/PGS000805.txt.gz - Check Terms/Licenses
PGS000806
(GRS582_T2Dafr)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000806/ScoringFiles/PGS000806.txt.gz - Check Terms/Licenses
PGS000807
(GRS582_T2Dasn)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000807/ScoringFiles/PGS000807.txt.gz - Check Terms/Licenses
PGS000808
(GRS582_T2Dhis)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000808/ScoringFiles/PGS000808.txt.gz - Check Terms/Licenses
PGS000832
(T2D-GRS)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 384
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000832/ScoringFiles/PGS000832.txt.gz
PGS000864
(T2D-gPRS)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 389,243
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000864/ScoringFiles/PGS000864.txt.gz
PGS000868
(T2D_221)
 PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 221
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000868/ScoringFiles/PGS000868.txt.gz
PGS001295
(GBE_HC165)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 385
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001295/ScoringFiles/PGS001295.txt.gz
PGS001357
(T2D_AnnoPred_PRS)
 PGP000252 |
Ye Y et al. Circ Genom Precis Med (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 2,996,761
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001357/ScoringFiles/PGS001357.txt.gz
PGS001781
(T2D_PRSCS)
 PGP000261 |
Tamlander M et al. Commun Biol (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,091,673
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001781/ScoringFiles/PGS001781.txt.gz
PGS001818
(portability-PLR_250.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 30,745
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001818/ScoringFiles/PGS001818.txt.gz
PGS002026
(portability-ldpred2_250.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 830,783
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002026/ScoringFiles/PGS002026.txt.gz
PGS002243
(ldpred_t2d)
 PGP000271 |
Mars N et al. Cell Genom (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,431,973
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz
PGS002308
(PRScsx_T2D)
 PGP000331 |
Ge T et al. Genome Med (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,259,754
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002308/ScoringFiles/PGS002308.txt.gz
PGS002354
(disease_T2D.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002354/ScoringFiles/PGS002354.txt.gz
Showing 4651 to 4700 of 5337 rows