Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002168
(portability-ldpred2_log_fat_free_mass)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Whole body fat-free mass lean body mass 966,825
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002168/ScoringFiles/PGS002168.txt.gz
PGS019541
(TPMI_611.3_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Lump or mass in breast breast neoplasm 966,845
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019541/ScoringFiles/PGS019541.txt.gz
PGS018564
(TPMI_185_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Prostate cancer prostate cancer 967,258
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018564/ScoringFiles/PGS018564.txt.gz
PGS018980
(TPMI_327.41_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Organic or persistent insomnia insomnia 967,358
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018980/ScoringFiles/PGS018980.txt.gz
PGS018711
(TPMI_246_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of thyroid thyroid gland disorder 967,487
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018711/ScoringFiles/PGS018711.txt.gz
PGS018594
(TPMI_195.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Malignant neoplasm other neoplasm 967,720
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018594/ScoringFiles/PGS018594.txt.gz
PGS019110
(TPMI_386.21_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Central origin vertigo Vertigo 968,081
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019110/ScoringFiles/PGS019110.txt.gz
PGS019467
(TPMI_593_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hematuria Hematuria 968,181
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019467/ScoringFiles/PGS019467.txt.gz
PGS019274
(TPMI_475_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic sinusitis chronic rhinosinusitis 968,351
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019274/ScoringFiles/PGS019274.txt.gz
PGS019095
(TPMI_386.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Peripheral or central vertigo Vertigo 968,450
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019095/ScoringFiles/PGS019095.txt.gz
PGS018733
(TPMI_250.4_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal glucose Abnormal blood glucose concentration 968,581
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018733/ScoringFiles/PGS018733.txt.gz
PGS018589
(TPMI_195_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer suspected or other cancer 969,101
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018589/ScoringFiles/PGS018589.txt.gz
PGS012545
(EN_model_IS)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Ischemic stroke Ischemic stroke 969,253
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012545/ScoringFiles/PGS012545.txt.gz
PGS019234
(TPMI_433.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Occlusion of cerebral arteries cerebral artery occlusion 969,384
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019234/ScoringFiles/PGS019234.txt.gz
PGS012544
(EN_model_HF)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Heart failure heart failure 969,507
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012544/ScoringFiles/PGS012544.txt.gz
PGS002694
(biochemistry_Glucose.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Glucose glucose measurement 969,640
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002694/ScoringFiles/PGS002694.txt.gz
PGS012541
(EN_model_Asthma)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Asthma Asthma 969,763
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012541/ScoringFiles/PGS012541.txt.gz
PGS012543
(EN_model_CKD)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Chronic kidney disease chronic kidney disease 969,768
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012543/ScoringFiles/PGS012543.txt.gz
PGS012540
(EN_model_Angina)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Angina angina pectoris 969,769
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012540/ScoringFiles/PGS012540.txt.gz
PGS012542
(EN_model_CAD)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Coronary artery disease coronary artery disorder 969,769
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012542/ScoringFiles/PGS012542.txt.gz
PGS012546
(EN_model_PAD)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Peripheral arterial disease peripheral arterial disease 969,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012546/ScoringFiles/PGS012546.txt.gz
PGS012547
(EN_model_T2D)
 PGP000790 |
Hu J et al. Genet Med (2026)
 Type 2 diabetes mellitus type 2 diabetes mellitus 969,771
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012547/ScoringFiles/PGS012547.txt.gz
PGS018780
(TPMI_250.41_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Impaired fasting glucose Impaired glucose tolerance 969,948
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018780/ScoringFiles/PGS018780.txt.gz
PGS002703
(biochemistry_LDLdirect.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 970,081
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002703/ScoringFiles/PGS002703.txt.gz
PGS005280
(IgE_GWAS_9260_Japanese_individuals_rev2.EAS)
 PGP000752 |
Sutoh Y et al. Am J Hum Genet (2025)
 Total IgE immunoglobulin E measurement 970,856
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005280/ScoringFiles/PGS005280.txt.gz
PGS018870
(TPMI_280_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Iron deficiency anemias Iron deficiency anemia 971,675
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018870/ScoringFiles/PGS018870.txt.gz
PGS002695
(biochemistry_HDLcholesterol.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 HDL cholesterol high density lipoprotein cholesterol measurement 971,682
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002695/ScoringFiles/PGS002695.txt.gz
PGS019711
(TPMI_728_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Disorders of muscle ligament and fascia soft tissue disease 971,989
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019711/ScoringFiles/PGS019711.txt.gz
PGS012586
(PRS_HNC_all)
 PGP000822 |
Lee YC et al. BMC Med (2024)
 Head and neck squamous cell carcinoma head and neck squamous cell carcinoma 972,182
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012586/ScoringFiles/PGS012586.txt.gz
PGS012587
(PRS_HNC_OC)
 PGP000822 |
Lee YC et al. BMC Med (2024)
 Oral cavity cancer oral cavity cancer 972,182
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012587/ScoringFiles/PGS012587.txt.gz
PGS012588
(PRS_HNC_OPC)
 PGP000822 |
Lee YC et al. BMC Med (2024)
 Oropharynx cancer oropharynx cancer 972,182
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012588/ScoringFiles/PGS012588.txt.gz
PGS000135
(SCZ_MTS)
 PGP000065 |
Zheutlin AB et al. Am J Psychiatry (2019)
 Schizophrenia schizophrenia 972,439
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000135/ScoringFiles/PGS000135.txt.gz
PGS019767
(TPMI_795_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other and nonspecific abnormal cytological histological and immunological findings cytological, histological or immunological finding 972,527
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019767/ScoringFiles/PGS019767.txt.gz
PGS019556
(TPMI_615_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Endometriosis endometriosis 972,671
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019556/ScoringFiles/PGS019556.txt.gz
PGS005327
(T2D_PRS_AMR)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 972,776
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005327/ScoringFiles/PGS005327.txt.gz
PGS002156
(portability-ldpred2_log_age_first_sex)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Age first had sexual intercourse age at first sexual intercourse measurement 972,919
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002156/ScoringFiles/PGS002156.txt.gz
PGS002682
(disease_CARDIOVASCULAR.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Cardiovascular disease cardiovascular disorder 972,965
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002682/ScoringFiles/PGS002682.txt.gz
PGS018509
(TPMI_155.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Malignant neoplasm of liver primary liver cancer 973,600
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018509/ScoringFiles/PGS018509.txt.gz
PGS002701
(disease_HYPERTENSION_DIAGNOSED.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 973,782
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002701/ScoringFiles/PGS002701.txt.gz
PGS019787
(TPMI_947_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urticaria urticaria 973,975
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019787/ScoringFiles/PGS019787.txt.gz
PGS002706
(blood_MEAN_PLATELET_VOL.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Mean platelet volume platelet volume 973,986
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002706/ScoringFiles/PGS002706.txt.gz
PGS019005
(TPMI_357_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Inflammatory and toxic neuropathy neuropathy 974,368
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019005/ScoringFiles/PGS019005.txt.gz
PGS004783
(HLD_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypercholesterolemia Hypercholesterolemia 975,107
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004783/ScoringFiles/PGS004783.txt.gz
PGS018676
(TPMI_242.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Graves disease Graves disease 975,251
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018676/ScoringFiles/PGS018676.txt.gz
PGS002801
(GIANT_HEIGHT_YENGO_2022_PGS_WEIGHTS_AFR)
 PGP000382 |
Yengo L et al. Nature (2022)
 Height body height 975,455
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002801/ScoringFiles/PGS002801.txt.gz
PGS018945
(TPMI_300.11_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Generalized anxiety disorder generalized anxiety disorder 975,855
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018945/ScoringFiles/PGS018945.txt.gz
PGS005367
(DPRISM_T2DPRS_trainedforEAS_SASweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 976,035
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005367/ScoringFiles/PGS005367.txt.gz
PGS004160
(UKBB_EnsPGS.GCST008972.Gout)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Gout gout 976,174
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004160/ScoringFiles/PGS004160.txt.gz
PGS019120
(TPMI_389.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Sensorineural hearing loss sensorineural hearing loss disorder 976,192
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019120/ScoringFiles/PGS019120.txt.gz
PGS019551
(TPMI_613.7_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other signs and symptoms in breast sign or symptom 976,239
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019551/ScoringFiles/PGS019551.txt.gz
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