Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003114
(ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 555,528
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003114/ScoringFiles/PGS003114.txt.gz
PGS019514
(TPMI_599.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Retention of urine Urinary retention 555,975
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019514/ScoringFiles/PGS019514.txt.gz
PGS019749
(TPMI_783_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fever of unknown origin fever of unknown origin 556,003
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019749/ScoringFiles/PGS019749.txt.gz
PGS003229
(ExPRSweb_Creatine_30510-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Creatine creatine level 557,260
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003229/ScoringFiles/PGS003229.txt.gz
PGS019402
(TPMI_577_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diseases of pancreas pancreas disorder 557,676
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019402/ScoringFiles/PGS019402.txt.gz
PGS004715
(ALT_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Alanine aminotransferase serum alanine aminotransferase amount 559,731
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004715/ScoringFiles/PGS004715.txt.gz
PGS018657
(TPMI_241.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Nontoxic uninodular goiter nontoxic goiter 561,432
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018657/ScoringFiles/PGS018657.txt.gz
PGS019230
(TPMI_433.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Occlusion of cerebral arteries cerebral artery occlusion 562,676
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019230/ScoringFiles/PGS019230.txt.gz
PGS003812
(logTG_EAS_CTSLEB)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 563,207
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003812/ScoringFiles/PGS003812.txt.gz
PGS002207
(portability-ldpred2_MCV)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Mean corpuscular volume erythrocyte volume 564,228
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002207/ScoringFiles/PGS002207.txt.gz
PGS003836
(height_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Height body height 564,325
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003836/ScoringFiles/PGS003836.txt.gz
PGS003843
(bmi_EUR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Body mass index (BMI) body mass index 564,332
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003843/ScoringFiles/PGS003843.txt.gz
PGS003795
(LDL_EAS_CTSLEB)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 564,379
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003795/ScoringFiles/PGS003795.txt.gz
PGS002116
(portability-ldpred2_ECG_P_duration)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 P duration P wave duration 564,874
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002116/ScoringFiles/PGS002116.txt.gz
PGS019634
(TPMI_706.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 565,294
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019634/ScoringFiles/PGS019634.txt.gz
PGS002124
(portability-ldpred2_ever_addicted)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ever addicted to any substance or behaviour addictive behaviour 566,292
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002124/ScoringFiles/PGS002124.txt.gz
PGS002066
(portability-ldpred2_555.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ulcerative colitis ulcerative colitis 566,637
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002066/ScoringFiles/PGS002066.txt.gz
PGS002710
(disease_PSORIASIS.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 566,839
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002710/ScoringFiles/PGS002710.txt.gz
PGS018928
(TPMI_292_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Neurological disorders nervous system disorder 566,907
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018928/ScoringFiles/PGS018928.txt.gz
PGS002200
(portability-ldpred2_log_vitaminD)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Vitamin D vitamin D level 567,735
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002200/ScoringFiles/PGS002200.txt.gz
PGS003139
(ExPRSweb_TC_30690-raw_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Total cholesterol total cholesterol measurement 569,518
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003139/ScoringFiles/PGS003139.txt.gz
PGS018462
(TPMI_145.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Tongue cancer tongue cancer 570,182
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018462/ScoringFiles/PGS018462.txt.gz
PGS002046
(portability-ldpred2_383)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Otosclerosis otosclerosis 570,308
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002046/ScoringFiles/PGS002046.txt.gz
PGS005328
(T2D_PRS_EAS)
 PGP000770 |
Hrytsenko Y et al. Commun Med (Lond) (2025)
 Type 2 Diabetes Mellitus type 2 diabetes mellitus 570,349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005328/ScoringFiles/PGS005328.txt.gz
PGS002119
(portability-ldpred2_ECG_QT_interval)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 QT interval QT interval 571,268
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002119/ScoringFiles/PGS002119.txt.gz
PGS012523
(DBP_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Diastolic blood pressure diastolic blood pressure 574,294
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012523/ScoringFiles/PGS012523.txt.gz
PGS012522
(SBP_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Systolic blood pressure systolic blood pressure 574,384
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012522/ScoringFiles/PGS012522.txt.gz
PGS002636
(cov_EDU_COLLEGE.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 College education educational attainment 577,448
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002636/ScoringFiles/PGS002636.txt.gz
PGS018751
(TPMI_250.21_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes with ketoacidosis type 2 diabetes mellitus 577,953
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018751/ScoringFiles/PGS018751.txt.gz
PGS004043
(ldpred2.CV.GCST007140.HDL)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 578,264
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004043/ScoringFiles/PGS004043.txt.gz
PGS003319
(ExPRSweb_Insomnia_1160_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Insomnia insomnia 578,551
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003319/ScoringFiles/PGS003319.txt.gz
PGS002860
(ExPRSweb_CRP_28887542-GCST004941_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 579,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002860/ScoringFiles/PGS002860.txt.gz
PGS019175
(TPMI_414_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other forms of chronic heart disease chronic pulmonary heart disease 583,608
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019175/ScoringFiles/PGS019175.txt.gz
PGS019871
(TPMI_HT_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Body height body height 583,972
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019871/ScoringFiles/PGS019871.txt.gz
PGS002070
(portability-ldpred2_565.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Anal and rectal polyp polyp of rectum,
anal polyp		 584,133
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002070/ScoringFiles/PGS002070.txt.gz
PGS019529
(TPMI_604_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Disorders of penis penile disorder 584,567
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019529/ScoringFiles/PGS019529.txt.gz
PGS004769
(Hb_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hemoglobin hemoglobin measurement 584,676
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004769/ScoringFiles/PGS004769.txt.gz
PGS003849
(PRSaddiction-rf)
 PGP000490 |
Hatoum AS et al. Nat Ment Health (2023)
 Addiction risk factors substance-related disorder 584,753
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003849/ScoringFiles/PGS003849.txt.gz
PGS002205
(portability-ldpred2_M_log_testosterone)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Testosterone (male only) testosterone measurement,
male		 584,991
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002205/ScoringFiles/PGS002205.txt.gz
PGS003134
(ExPRSweb_TC_30690-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Total cholesterol total cholesterol measurement 585,328
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003134/ScoringFiles/PGS003134.txt.gz
PGS004739
(BUN_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Urea urea measurement 587,237
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004739/ScoringFiles/PGS004739.txt.gz
PGS019197
(TPMI_427.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atrial fibrillation and flutter atrial fibrillation 587,354
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019197/ScoringFiles/PGS019197.txt.gz
PGS004707
(Albumin_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Albumin serum albumin amount 589,303
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004707/ScoringFiles/PGS004707.txt.gz
PGS019879
(TPMI_sCR_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Serum creatinine serum creatinine amount 589,678
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019879/ScoringFiles/PGS019879.txt.gz
PGS002054
(portability-ldpred2_442.11)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Abdominal aortic aneurysm abdominal aortic aneurysm 592,187
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002054/ScoringFiles/PGS002054.txt.gz
PGS005380
(Erpos_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor positive breast cancer estrogen-receptor positive breast cancer 592,247
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005380/ScoringFiles/PGS005380.txt.gz
PGS002644
(lung_FVCzSMOKE.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Forced vital capacity vital capacity 592,696
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002644/ScoringFiles/PGS002644.txt.gz
PGS002204
(portability-ldpred2_M_less_hair)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hair/balding pattern balding measurement 593,179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002204/ScoringFiles/PGS002204.txt.gz
PGS002167
(portability-ldpred2_log_eosinophil_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Eosinophil percentage eosinophil percentage of leukocytes 593,459
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002167/ScoringFiles/PGS002167.txt.gz
PGS004851
(TotalProtein_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Total protein measurement total blood protein measurement 593,738
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004851/ScoringFiles/PGS004851.txt.gz
Showing 4101 to 4150 of 6972 rows