Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002191
(portability-ldpred2_log_platelet)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Platelet count platelet count 663,591
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002191/ScoringFiles/PGS002191.txt.gz
PGS002074
(portability-ldpred2_593)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hematuria Hematuria 664,167
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002074/ScoringFiles/PGS002074.txt.gz
PGS019400
(TPMI_577_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Diseases of pancreas pancreas disorder 664,654
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019400/ScoringFiles/PGS019400.txt.gz
PGS002147
(portability-ldpred2_immature_reticulocyte_frac)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Immature reticulocyte fraction reticulocyte amount 664,696
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002147/ScoringFiles/PGS002147.txt.gz
PGS019267
(TPMI_472_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic pharyngitis and nasopharyngitis pharyngitis 666,847
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019267/ScoringFiles/PGS019267.txt.gz
PGS002019
(portability-ldpred2_208)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Benign neoplasm of colon benign colon neoplasm 667,546
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002019/ScoringFiles/PGS002019.txt.gz
PGS002117
(portability-ldpred2_ECG_PP_interval)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 PP interval PP interval 667,705
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002117/ScoringFiles/PGS002117.txt.gz
PGS002754
(Asthma_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Asthma asthma 668,286
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002754/ScoringFiles/PGS002754.txt.gz
PGS004148
(sbayesr.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 671,211
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004148/ScoringFiles/PGS004148.txt.gz
PGS002185
(portability-ldpred2_log_microalbumin_urine)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Microalbumin in urine urinary microalbumin measurement 671,610
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002185/ScoringFiles/PGS002185.txt.gz
PGS002043
(portability-ldpred2_365)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Glaucoma glaucoma 672,952
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002043/ScoringFiles/PGS002043.txt.gz
PGS004060
(megaprs.auto.GCST008972.Gout)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Gout gout 677,631
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004060/ScoringFiles/PGS004060.txt.gz
PGS004061
(megaprs.auto.GCST008972.Urate)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Urate urate measurement 677,631
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004061/ScoringFiles/PGS004061.txt.gz
PGS004076
(megaprs.CV.GCST008972.Gout)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Gout gout 677,631
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004076/ScoringFiles/PGS004076.txt.gz
PGS004077
(megaprs.CV.GCST008972.Urate)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Urate urate measurement 677,631
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004077/ScoringFiles/PGS004077.txt.gz
PGS018524
(TPMI_165.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of bronchus lung bronchus cancer 679,083
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018524/ScoringFiles/PGS018524.txt.gz
PGS002101
(portability-ldpred2_apoA)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Apolipoprotein A apolipoprotein A 1 measurement 681,234
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002101/ScoringFiles/PGS002101.txt.gz
PGS003457
(GRS_ICH)
 PGP000450 |
Mayerhofer E et al. Stroke (2023)
 Intracerebral hemorrhage intracerebral hemorrhage 682,890
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003457/ScoringFiles/PGS003457.txt.gz
PGS004141
(sbayesr.auto.GCST007954.HbA1c)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 HbA1c HbA1c measurement 683,029
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004141/ScoringFiles/PGS004141.txt.gz
PGS019162
(TPMI_411.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Myocardial infarction myocardial infarction 684,078
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019162/ScoringFiles/PGS019162.txt.gz
PGS018885
(TPMI_282_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hereditary hemolytic anemias familial hemolytic anemia 685,561
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018885/ScoringFiles/PGS018885.txt.gz
PGS018725
(TPMI_250.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 687,652
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018725/ScoringFiles/PGS018725.txt.gz
PGS004062
(megaprs.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 691,136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004062/ScoringFiles/PGS004062.txt.gz
PGS002065
(portability-ldpred2_550.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Inguinal hernia Inguinal hernia 691,268
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002065/ScoringFiles/PGS002065.txt.gz
PGS018562
(TPMI_185_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Prostate cancer prostate cancer 691,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018562/ScoringFiles/PGS018562.txt.gz
PGS005129
(forEAS_fromEUR)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 692,328
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005129/ScoringFiles/PGS005129.txt.gz
PGS004886
(INTERVENE_MegaPRS_Melanoma)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Melanoma melanoma 692,834
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004886/ScoringFiles/PGS004886.txt.gz
PGS019502
(TPMI_598_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Abnormal findings on examination of urine urinary system disorder 694,136
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019502/ScoringFiles/PGS019502.txt.gz
PGS003302
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 695,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003302/ScoringFiles/PGS003302.txt.gz
PGS019116
(TPMI_389.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Sensorineural hearing loss sensorineural hearing loss disorder 697,131
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019116/ScoringFiles/PGS019116.txt.gz
PGS002229
(portability-ldpred2_urate)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Urate urate measurement 698,001
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002229/ScoringFiles/PGS002229.txt.gz
PGS005126
(forEAS_fromAFR)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 699,919
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005126/ScoringFiles/PGS005126.txt.gz
PGS002106
(portability-ldpred2_calcium)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Calcium calcium measurement 702,009
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002106/ScoringFiles/PGS002106.txt.gz
PGS019245
(TPMI_433.8_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Late effects of cerebrovascular disease cerebrovascular disorder 703,260
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019245/ScoringFiles/PGS019245.txt.gz
PGS002188
(portability-ldpred2_log_platelet_crit)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Platelet crit platelet crit 703,576
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002188/ScoringFiles/PGS002188.txt.gz
PGS019562
(TPMI_626_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Disorders of menstruation and other abnormal bleeding from female genital tract menstrual disorder 704,441
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019562/ScoringFiles/PGS019562.txt.gz
PGS003149
(ExPRSweb_TG_30870-raw_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Triglycerides triglyceride measurement 705,677
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003149/ScoringFiles/PGS003149.txt.gz
PGS002199
(portability-ldpred2_log_ventricular_rate)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ventricular rate ventricular rate measurement 705,680
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002199/ScoringFiles/PGS002199.txt.gz
PGS002040
(portability-ldpred2_361)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Retinal detachments and defects retinal detachment 706,872
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002040/ScoringFiles/PGS002040.txt.gz
PGS005130
(forEAS_fromSAS)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 708,315
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005130/ScoringFiles/PGS005130.txt.gz
PGS002216
(portability-ldpred2_phosphate)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Phosphate phosphate measurement 708,693
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002216/ScoringFiles/PGS002216.txt.gz
PGS005234
(F3_Body_Size_and_Adipose_Distribution)
 PGP000739 |
Arehart CH et al. Nat Commun (2025)
 Body size and adipose distribution body weight,
body fat distribution		 709,193
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005234/ScoringFiles/PGS005234.txt.gz
PGS019215
(TPMI_430_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Intracranial hemorrhage intracranial hemorrhage 709,249
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019215/ScoringFiles/PGS019215.txt.gz
PGS004862
(hermes.mtag)
 PGP000608 |
Zheng SL et al. Nat Genet (2024)
 Dilated cardiomyopathy (MTAG) dilated cardiomyopathy 709,534
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004862/ScoringFiles/PGS004862.txt.gz
PGS005235
(F4_Adiposity)
 PGP000739 |
Arehart CH et al. Nat Commun (2025)
 Adiposity obesity disorder 709,828
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005235/ScoringFiles/PGS005235.txt.gz
PGS005225
(F4_Frailty)
 PGP000735 |
Foote IF et al. Nat Genet (2025)
 Factor 4 (metabolic/respiratory problems) of frailty frailty measurement 710,413
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005225/ScoringFiles/PGS005225.txt.gz
PGS005233
(F2_Abdominal_Size)
 PGP000739 |
Arehart CH et al. Nat Commun (2025)
 Abdominal size body fat distribution 710,487
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005233/ScoringFiles/PGS005233.txt.gz
PGS005232
(F1_Birth_Size)
 PGP000739 |
Arehart CH et al. Nat Commun (2025)
 Birth size birth weight 710,799
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005232/ScoringFiles/PGS005232.txt.gz
PGS002044
(portability-ldpred2_366)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Cataract cataract 711,169
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002044/ScoringFiles/PGS002044.txt.gz
PGS019051
(TPMI_368_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Visual disturbances Abnormality of vision 711,283
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019051/ScoringFiles/PGS019051.txt.gz
Showing 4201 to 4250 of 6972 rows