Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002840
(ExPRSweb_BMI_21001-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Body mass index (BMI) body mass index 1,062,550
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002840/ScoringFiles/PGS002840.txt.gz
PGS003588
(SBP)
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Systolic blood pressure systolic blood pressure 1,064,898
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003588/ScoringFiles/PGS003588.txt.gz
PGS003328
(ExPRSweb_Insomnia_1200_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Insomnia insomnia 1,065,129
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003328/ScoringFiles/PGS003328.txt.gz
PGS004607
(AMD-MVP-AFR)
 PGP000582 |
Gorman BR et al. Nat Genet (2024)
 Age-related macular degeneration age-related macular degeneration 1,067,520
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004607/ScoringFiles/PGS004607.txt.gz
PGS003884
(BMI_PRScsx_ARB_AMRweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 Body mass index (BMI) body mass index 1,067,771
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003884/ScoringFiles/PGS003884.txt.gz
PGS003888
(Height_PRScsx_ARB_AMRweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 Height body height 1,067,771
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003888/ScoringFiles/PGS003888.txt.gz
PGS003870
(LDL_PRScsx_ARB_AMRweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,067,857
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003870/ScoringFiles/PGS003870.txt.gz
PGS003876
(HDL_PRScsx_ARB_AMRweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,067,858
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003876/ScoringFiles/PGS003876.txt.gz
PGS003867
(T2D_PRScs_ARB)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,068,166
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003867/ScoringFiles/PGS003867.txt.gz
PGS004948
(DCM_GWAS_exclUKB)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy dilated cardiomyopathy 1,068,761
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004948/ScoringFiles/PGS004948.txt.gz
PGS003873
(LDL_PRScsx_ARB_EURweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,069,677
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003873/ScoringFiles/PGS003873.txt.gz
PGS003879
(HDL_PRScsx_ARB_EURweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,069,677
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003879/ScoringFiles/PGS003879.txt.gz
PGS005100
(psa2024_prs_disc)
 PGP000692 |
Hoffmann TJ et al. Nat Genet (2025)
 Prostate specific antigen prostate specific antigen amount 1,070,227
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005100/ScoringFiles/PGS005100.txt.gz
PGS005101
(psa2024_prs_joint)
 PGP000692 |
Hoffmann TJ et al. Nat Genet (2025)
 Prostate specific antigen prostate specific antigen amount 1,070,230
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005101/ScoringFiles/PGS005101.txt.gz
PGS000365
(PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Esophageal cancer esophageal cancer 1,070,434
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000365/ScoringFiles/PGS000365.txt.gz
PGS003379
(PSA_PGS_CSx)
 PGP000412 |
Kachuri L et al. Nat Med (2023)
 Prostate-specific antigen (PSA) levels prostate specific antigen amount 1,071,278
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003379/ScoringFiles/PGS003379.txt.gz
PGS003982
(dbslmm.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,071,764
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003982/ScoringFiles/PGS003982.txt.gz
PGS004152
(UKBB_EnsPGS.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,071,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004152/ScoringFiles/PGS004152.txt.gz
PGS004947
(DCM_MTAG_exclMGBB)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy (MTAG) dilated cardiomyopathy 1,072,247
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004947/ScoringFiles/PGS004947.txt.gz
PGS000449
(PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 1,073,162
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000449/ScoringFiles/PGS000449.txt.gz
PGS004081
(prscs.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,073,268
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004081/ScoringFiles/PGS004081.txt.gz
PGS004097
(prscs.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,073,268
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004097/ScoringFiles/PGS004097.txt.gz
PGS003362
(GSCAN_AgeSmk_2022_PRS_WEIGHTS_AMR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Age of smoking initiation age at initiation of smoking 1,073,689
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003362/ScoringFiles/PGS003362.txt.gz
PGS004951
(DCM_MTAG_exclAUMC)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy (MTAG) dilated cardiomyopathy 1,075,760
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004951/ScoringFiles/PGS004951.txt.gz
PGS004751
(current_smoker_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Current smoker smoking status measurement 1,076,735
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004751/ScoringFiles/PGS004751.txt.gz
PGS004687
(bladder_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Bladder cancer urinary bladder carcinoma 1,077,775
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004687/ScoringFiles/PGS004687.txt.gz
PGS004689
(colorectal_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Colorectal cancer colorectal carcinoma 1,077,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004689/ScoringFiles/PGS004689.txt.gz
PGS002765
(SBP_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 1,077,894
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002765/ScoringFiles/PGS002765.txt.gz
PGS000383
(PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of rectum, rectosigmoid junction, and anus rectosigmoid junction neoplasm,
rectal cancer		 1,078,799
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000383/ScoringFiles/PGS000383.txt.gz
PGS000335
(BC_PRSCS)
 PGP000102 |
Mars N et al. Nat Commun (2020)
 Breast cancer breast carcinoma 1,079,089
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000335/ScoringFiles/PGS000335.txt.gz
PGS012539
(pSSNS)
 PGP000789 |
Barry A et al. Nat Commun (2023)
 Pediatric steroid-sensitive nephrotic syndrome nephrotic syndrome 1,081,086
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012539/ScoringFiles/PGS012539.txt.gz
PGS000363
(PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Esophageal cancer esophageal cancer 1,081,646
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000363/ScoringFiles/PGS000363.txt.gz
PGS003425
(prscs_hemoglobin)
 PGP000432 |
Toivonen J et al. Vox Sanguinis (2023)
 Hemoglobin hemoglobin measurement 1,082,250
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003425/ScoringFiles/PGS003425.txt.gz
PGS004614
(DivD_SNPWeights)
 PGP000592 |
Wu Y et al. Cell Genom (2023)
 Diverticular disease diverticular disease 1,082,282
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004614/ScoringFiles/PGS004614.txt.gz
PGS003426
(prscs_ferritin)
 PGP000432 |
Toivonen J et al. Vox Sanguinis (2023)
 Ferritin ferritin measurement 1,082,414
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003426/ScoringFiles/PGS003426.txt.gz
PGS002761
(Glaucoma_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Glaucoma glaucoma 1,082,518
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002761/ScoringFiles/PGS002761.txt.gz
PGS004825
(RDW_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Red cell distribution width Red cell distribution width 1,082,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004825/ScoringFiles/PGS004825.txt.gz
PGS000202
(PROB_ALC_FT12)
 PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
 Problematic alcohol use alcohol dependence measurement 1,083,002
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000202/ScoringFiles/PGS000202.txt.gz
PGS002769
(Rheumatoid_arthritis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Seropositive rheumatoid arthritis rheumatoid arthritis 1,083,565
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002769/ScoringFiles/PGS002769.txt.gz
PGS002807
(PRSCS_SBP)
 PGP000384 |
Parcha V et al. Circ Genom Precis Med (2022)
 Systolic blood pressure systolic blood pressure 1,084,157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002807/ScoringFiles/PGS002807.txt.gz
PGS005274
(tc_vs_bng_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma vs benign nodular goiter benign,
nodular goiter,
thyroid gland carcinoma		 1,084,965
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005274/ScoringFiles/PGS005274.txt.gz
PGS005272
(lymphocytic_thyroiditis_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Lymphocytic thyroiditis Hashimoto thyroiditis 1,085,142
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005272/ScoringFiles/PGS005272.txt.gz
PGS005271
(lymphocytic_thyroiditis_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Lymphocytic thyroiditis Hashimoto thyroiditis 1,085,156
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005271/ScoringFiles/PGS005271.txt.gz
PGS005273
(tc_vs_bng_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma vs benign nodular goiter benign,
nodular goiter,
thyroid gland carcinoma		 1,085,164
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005273/ScoringFiles/PGS005273.txt.gz
PGS005260
(thyroid_cancer_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma thyroid gland carcinoma 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005260/ScoringFiles/PGS005260.txt.gz
PGS005263
(benign_nodular_goiter_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Benign nodular goiter benign,
nodular goiter		 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005263/ScoringFiles/PGS005263.txt.gz
PGS005266
(graves_disease_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Graves' disease Graves disease 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005266/ScoringFiles/PGS005266.txt.gz
PGS005269
(hypothyroidism_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Hypothyroidism hypothyroidism 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005269/ScoringFiles/PGS005269.txt.gz
PGS005259
(thyroid_cancer_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma thyroid gland carcinoma 1,085,173
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005259/ScoringFiles/PGS005259.txt.gz
PGS005262
(benign_nodular_goiter_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Benign nodular goiter benign,
nodular goiter		 1,085,173
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005262/ScoringFiles/PGS005262.txt.gz
Showing 4401 to 4450 of 5337 rows