Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002687
(disease_DIABETES_ANY_DIAGNOSED.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Diabetes (any type) diabetes mellitus 923,080
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002687/ScoringFiles/PGS002687.txt.gz
PGS005135
(forEUR_fromSAS)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 923,118
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005135/ScoringFiles/PGS005135.txt.gz
PGS005299
(Jorda_HF_MTAG-PGS-inf_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Heart failure heart failure 923,722
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005299/ScoringFiles/PGS005299.txt.gz
PGS005300
(Jorda_HF_MTAG-PGS_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Heart failure heart failure 923,722
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005300/ScoringFiles/PGS005300.txt.gz
PGS005301
(Jorda_HF_MTAG-PGS_females_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Heart failure heart failure 923,722
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005301/ScoringFiles/PGS005301.txt.gz
PGS005302
(Jorda_HF_MTAG-PGS_males_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Heart failure heart failure 923,722
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005302/ScoringFiles/PGS005302.txt.gz
PGS002678
(disease_AID_ALL.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Autoimmune disease autoimmune disease 923,726
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002678/ScoringFiles/PGS002678.txt.gz
PGS002696
(pigment_HAIR.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hair color strand of hair color 924,497
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002696/ScoringFiles/PGS002696.txt.gz
PGS002149
(portability-ldpred2_insomnia)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Sleeplessness / insomnia insomnia 926,585
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002149/ScoringFiles/PGS002149.txt.gz
PGS002196
(portability-ldpred2_log_sleep)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Sleep duration sleep duration trait 927,619
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002196/ScoringFiles/PGS002196.txt.gz
PGS019115
(TPMI_389_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hearing loss hearing loss disorder 928,045
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019115/ScoringFiles/PGS019115.txt.gz
PGS019782
(TPMI_939_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 928,454
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019782/ScoringFiles/PGS019782.txt.gz
PGS019696
(TPMI_716.9_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Arthropathy NOS arthropathy 928,818
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019696/ScoringFiles/PGS019696.txt.gz
PGS019452
(TPMI_586_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other disorders of the kidney and ureters urinary system disorder 929,458
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019452/ScoringFiles/PGS019452.txt.gz
PGS005366
(DPRISM_T2DPRS_trainedforEAS_EURweights)
 PGP000773 |
Huerta-Chagoya A et al. medRxiv (2025)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 929,716
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005366/ScoringFiles/PGS005366.txt.gz
PGS018619
(TPMI_211_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Benign neoplasm of other parts of digestive system benign digestive system neoplasm 929,927
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018619/ScoringFiles/PGS018619.txt.gz
PGS004036
(ldpred2.auto.GCST90018959.Height)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Height body height 929,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004036/ScoringFiles/PGS004036.txt.gz
PGS002230
(portability-ldpred2_water_intake)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Water intake drinking behavior 930,461
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002230/ScoringFiles/PGS002230.txt.gz
PGS004136
(sbayesr.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 930,497
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004136/ScoringFiles/PGS004136.txt.gz
PGS004870
(INTERVENE_MegaPRS_T2D)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 930,506
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004870/ScoringFiles/PGS004870.txt.gz
PGS019159
(TPMI_411_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Ischemic Heart Disease myocardial ischemia 931,264
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019159/ScoringFiles/PGS019159.txt.gz
PGS003390
(best_HNSC)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Head and neck squamous cell carcinoma head and neck squamous cell carcinoma 931,477
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003390/ScoringFiles/PGS003390.txt.gz
PGS002126
(portability-ldpred2_ever_smoked)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ever smoked smoking status measurement 931,635
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002126/ScoringFiles/PGS002126.txt.gz
PGS019105
(TPMI_386.9_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dizziness and giddiness Light headedness and vertigo dizziness,
Vertigo		 931,755
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019105/ScoringFiles/PGS019105.txt.gz
PGS000359
(PRSWEB_PHECODE145.2_C3-TONGUENAS_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Tongue cancer tongue neoplasm 931,954
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000359/ScoringFiles/PGS000359.txt.gz
PGS002148
(portability-ldpred2_income)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Average total household income before tax household income 932,197
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002148/ScoringFiles/PGS002148.txt.gz
PGS003263
(ExPRSweb_Creatine_eGFRcrea-overall-IV-2GC_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine level		 932,548
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003263/ScoringFiles/PGS003263.txt.gz
PGS003278
(ExPRSweb_Creatine_eGFRcrea-overall-IV-2GC_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine level		 932,878
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003278/ScoringFiles/PGS003278.txt.gz
PGS003303
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 933,013
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003303/ScoringFiles/PGS003303.txt.gz
PGS003318
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 933,341
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003318/ScoringFiles/PGS003318.txt.gz
PGS019334
(TPMI_531_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Peptic ulcer excl esophageal Peptic ulcer 933,417
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019334/ScoringFiles/PGS019334.txt.gz
PGS018614
(TPMI_208_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Benign neoplasm of colon benign colon neoplasm 933,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018614/ScoringFiles/PGS018614.txt.gz
PGS002114
(portability-ldpred2_diastolic_BP)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Diastolic blood pressure, automated reading diastolic blood pressure 933,950
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002114/ScoringFiles/PGS002114.txt.gz
PGS019314
(TPMI_523.3_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Periodontitis acute or chronic acute pericementitis 934,116
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019314/ScoringFiles/PGS019314.txt.gz
PGS002677
(disease_ASTHMA_DIAGNOSED.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Asthma asthma 934,369
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002677/ScoringFiles/PGS002677.txt.gz
PGS002788
(BD2_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Type 2 bipolar disorder bipolar II disorder 935,292
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002788/ScoringFiles/PGS002788.txt.gz
PGS019174
(TPMI_411.8_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other chronic ischemic heart disease unspecified chronic pulmonary heart disease 935,962
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019174/ScoringFiles/PGS019174.txt.gz
PGS019526
(TPMI_600_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hyperplasia of prostate benign prostatic hyperplasia 936,087
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019526/ScoringFiles/PGS019526.txt.gz
PGS019462
(TPMI_591_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary tract infection urinary tract infection 936,271
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019462/ScoringFiles/PGS019462.txt.gz
PGS019015
(TPMI_362_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other retinal disorders retinal disorder 936,613
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019015/ScoringFiles/PGS019015.txt.gz
PGS002228
(portability-ldpred2_systolic_BP)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Systolic blood pressure, automated reading systolic blood pressure 937,030
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002228/ScoringFiles/PGS002228.txt.gz
PGS019304
(TPMI_523_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Gingival and periodontal diseases tooth disorder 937,449
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019304/ScoringFiles/PGS019304.txt.gz
PGS002787
(BD1_SDPR)
 PGP000370 |
Gui Y et al. Transl Psychiatry (2022)
 Type 1 bipolar disorder bipolar I disorder 937,511
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002787/ScoringFiles/PGS002787.txt.gz
PGS002700
(disease_HI_CHOL_SELF_REP.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 High cholesterol Hypercholesterolemia 937,601
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002700/ScoringFiles/PGS002700.txt.gz
PGS004850
(Total_protein_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Total protein measurement total blood protein measurement 937,777
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004850/ScoringFiles/PGS004850.txt.gz
PGS002217
(portability-ldpred2_play_computer)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Plays computer games lifestyle measurement 938,047
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002217/ScoringFiles/PGS002217.txt.gz
PGS019706
(TPMI_724_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other and unspecified disorders of back Abnormality of the vertebral column 939,653
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019706/ScoringFiles/PGS019706.txt.gz
PGS019774
(TPMI_796_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Elevated prostate specific antigen PSA prostate specific antigen amount 939,689
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019774/ScoringFiles/PGS019774.txt.gz
PGS019820
(TPMI_HbA1c_LDPred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Glycated hemoglobin HbA1c measurement 939,718
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019820/ScoringFiles/PGS019820.txt.gz
PGS019818
(TPMI_FG_LDPred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Fasting glucose glucose measurement 939,736
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019818/ScoringFiles/PGS019818.txt.gz
Showing 4601 to 4650 of 6972 rows