PGS Sample Set (PSS): PSS000335

Phenotype CHD was defined as occurrence of either myocardial infarction (MI) or coronary revascularization events (such as percutaneous coronary intervention or coronary artery bypass grafting) using ICD codes. Individuals with MI were defined as those whose EHR included at least two related diagnostic codes on separate occasions within a 5-day window, and individuals with coronary revascularization were defined as those who had at least one relevant procedural code in the EHR. ICD codelists and phenotyping algorithm in PMID:27678441 and PMID:25717410
Sample Ancestry Hispanic or Latin American

Sample Numbers

Total number
2,493 individuals
Detailed numbers
419 cases (16.81%)
2,074 controls
36.2% Male samples
Participant Follow-up Time
  • Median : 10.4 years
  • Iqr : [5.7, 14.7] years
Age of Study Participants
  • Mean : 41.1 years
  • Sd : 13.2 years
Number of Cohort(s) 8
Sample distribution
Sample gender distribution

Cohort(s)

Cohort Short Name Cohort Full Name Previous/other/additional names (e.g. sub-cohorts)
BioMe BioMe® BioBank Program (Institute for Personalized Medicine at the Icahn School of Medicine at Mount Sinai) BioMe Biobank (BMBB), MT. SINAI BioMe Biobank Platform (IMP), Charles R Bronfman Institute for Personalized Medicine - IPM / BioBank Genome Wide Association Study of Cardiovascular, Renal and Metabolic Phenotypes (IPM), Charles R Bronfman Institute for Personalized Medicine - IPM / BioBank Genome Wide Association Study of Cardiovascular, Renal and Metabolic Phenotypes I (IPM I), Charles R Bronfman Institute for Personalized Medicine - IPM / BioBank Genome Wide Association Study of Cardiovascular, Renal and Metabolic Phenotypes II (IPM II), IPM_EA_Affy, IPM_EA_Illu, Mount Sinai BioMe BioBank (Mount Sinai)
BioVU BioVU, the Vanderbilt DNA Databank project
Columbia Columbia University Medical Center
eMERGE Medical Records and Genomics study
KP Kaiser Permanente
MAYO The Mayo Clinic study MAYO clinic biobank
Nugene NUgene (Northwestern University)
PHB Partners HealthCare Biobank

Additional information

right censored at age 75 years or at the age of last observation (whichever was first)