PGS Sample Set (PSS): PSS000486

Phenotype Women (European Ancestry) diagnosed with unilateral breast cancer or metachronous contralateral breast cancer (CBC). Metachronous contralateral breast cancer was defined as breast cancer in the contralateral breast (in situ or invasive) diagnosed at least 3 months after the first breast cancer.
Sample Ancestry European

Sample Numbers

Total number
56,068 individuals
Detailed numbers
923 cases (1.65%)
55,145 controls
0.0% Male samples
Participant Follow-up Time Median : 8.4 years
Age of Study Participants Median (Age At Diagnosis) : 56.0 years
Number of Cohort(s) 42
Sample distribution
Sample gender distribution


Cohort Short Name Cohort Full Name Previous/other/additional names (e.g. sub-cohorts)
ABCFS Australian Breast Cancer Family Study
ABCS Amsterdam Breast Cancer Study
ABCS-F Amsterdam Breast Cancer Study - Familial
ABCTB Australian Breast Cancer Tissue Bank
AOCS Australian Ovarian Cancer Study
BBCC Bavarian Breast Cancer Cases and Controls
BCFR-PA Philadelphia Breast Cancer Family Registry
BIGGS Breast Cancer In Galway Genetic Study
BREOGAN Breast Oncology Galicia Network
BSUCH Breast Cancer Study of the University Clinic Heidelberg
CCGP Crete Cancer Genetics Program
CGPS Copenhagen General Population Study
GC-HBOC German Consortium for Hereditary Breast & Ovarian Cancer
GENICA Gene Environment Interaction and Breast Cancer in Germany
HCSC Hospital Clinico San Carlos
HEBCS Helsinki Breast Cancer Study
KARBAC Karolinska Breast Cancer Study
KARMA Karolinska Mammography Project for Risk Prediction of Breast Cancer – Cohort Study
kConFab Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer
LMBC Leuven Multidisciplinary Breast Centre
MABCS Macedonian Breast Cancer Study
MARIE Mammary Carcinoma Risk Factor Investigation
MBCSG Milan Breast Cancer Study Group
MCBCS Mayo Clinic Breast Cancer Study
MEC Multiethnic Cohort Study of Diet and Health
MISS Departments of Cancer Epidemiology and Oncology University Hospital Lund
NBCS Nijmegen Bladder Cancer Study
NC-BCFR Northern California Breast Cancer Family Registry
OBCS Oulu Breast Cancer Study
OFBCR Ontario Familial Breast Cancer Registry
ORIGO Leiden University Medical Centre Breast Cancer Study
PBCS Polish Breast Cancer Study
pKARMA Karolinska Mammography Project for Risk Prediction of Breast Cancer
POSH Prospective Study of Outcomes in Sporadic Versus Hereditary Breast Cancer Study
PROCAS Breast Screening Programme (NHSBSP) in Greater Manchester
RBCS Rotterdam Breast Cancer Study
SASBAC Singapore and Sweden Breast Cancer Study
SBCS Shanghai Breast Cancer Study
SEARCH Study of Epidemiology and Risk Factors in Cancer Heredity
SKKDKFZS St_dtisches Klinikum Karlsruhe Deutsches Krebsforschungszentrum Study
SZBCS IHCC-Szczecin Breast Cancer Study
UCIBCS UCI Breast Cancer Study