PGS Sample Set (PSS): PSS000995

Sample #1

Phenotype Cases are women with breast cancer. Of the 4414 breast cancer cases, 2470 were ER-positive and 1372 were ER-negative.
Sample Ancestry African American or Afro-Caribbean

Sample Numbers

Total number
9,542 individuals
Detailed numbers
4,414 cases (46.26%)
5,128 controls
0.0% Male samples
Number of Cohort(s) 10
Sample distribution
Sample gender distribution

Cohort(s)

Cohort Short Name Cohort Full Name Previous/other/additional names (e.g. sub-cohorts)
BWHS Black Womens Health Study
CARE Los Angeles component of The Womens Contraceptive and Reproductive Experiences Study
CBCS Carolina Breast Cancer Study
MEC Multiethnic Cohort Study of Diet and Health
NBHS Nashville Breast Health Study
NC-BCFR Northern California Breast Cancer Family Registry
PLCO Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
SFBCS San Francisco Bay Area Breast Cancer Study
WCHS Womens Circle of Health Study
WFBC Wake Forest University Breast Cancer Study

Additional information

All cohorts part of African American Breast Cancer (AABC) consortium and/or The African American Breast Cancer Epidemiology and Risk (AMBER)consortium.

Sample #2

Phenotype Cases are women with breast cancer. Of the 3928 breast cancer cases, 1533 were ER-positive and 987 were ER-negative.
Sample Ancestry African American or Afro-Caribbean, Sub-Saharan African, African unspecified

Sample Numbers

Total number
7,363 individuals
Detailed numbers
3,928 cases (53.35%)
3,435 controls
0.0% Male samples
Age of Study Participants Mean : 47.71 years
Number of Cohort(s) 15
Sample distribution
Sample gender distribution

Cohort(s)

Cohort Short Name Cohort Full Name Previous/other/additional names (e.g. sub-cohorts)
2SISTER The Two Sister Study
BBCS British Breast Cancer Study
BNCS Barbados National Cancer Study
CCPS Chicago Cancer Prone Study
MEC Multiethnic Cohort Study of Diet and Health
NBHS Nashville Breast Health Study
NC-BCFR Northern California Breast Cancer Family Registry
NCBCS North Carolina Bladder Cancer Study
NigBCS Nigerian Breast Cancer Study
PLCO Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
RVGBC Racial Variability in Genotypic Determinants of Breast Cancer Risk Study
SCCS NBHS/Southern Community Cohort
SISTER The Sister Study
USRT US Radiologic Technologist Study
WAABCS Women of African Ancestry Breast Cancer Study

Additional information

All cohorts part of The GAME-ON OncoArray Consortium or The GWAS of Breast Cancer in the African Diaspora Consortium (ROOT)

Sample #3

Phenotype Cases are women with breast cancer. Of the 899 breast cancer cases, 296 were ER-positive and 277 were ER-negative.
Sample Ancestry Sub-Saharan African

Sample Numbers

Total number
2,529 individuals
Detailed numbers
899 cases (35.55%)
1,630 controls
0.0% Male samples
Number of Cohort(s) 1
Sample distribution
Sample gender distribution

Cohort(s)

Cohort Short Name Cohort Full Name Previous/other/additional names (e.g. sub-cohorts)
GBHS Ghana Breast Health Study