PGS Sample Set (PSS): PSS001048

Phenotype Cases are individuals with type 2 diabetes (T2D). T2D cases were defined as individualswith (1) a T2D diagnosis by a physician/medical professional and use of medication for treat-mentofdiabetes,and/or (2)a fasting(R8h)blood glucose measurement R126 mg/dL indicated in examination records. For the MEC cohort, T2D cases were defined using the following criteria: (a) a self-report of diabetes on the baseline questionnaire, 2nd questionnaire or 3rd questionnaire; and (b) self-report of taking medication for T2D at the time of blood draw; and (c) no diagnosis of T1D in the absence of a T2D diagnosis from the California Office of Statewide Health Planning and Development (OSHPD) for California Residents. In addition, cases included individuals who were linked to the diabetes registries of Hawaii Medical Service Association (HMSA) or Kaiser Permanente Hawaii (KPH) health plans, or who were designated as diabetic in the Chronic Conditions Data Warehouse (CCW) of Medicare.
Sample Ancestry Oceanian (Native Hawaiian)

Sample Numbers

Total number
3,551 individuals
Detailed numbers
1,534 cases (43.2%)
2,017 controls
Number of Cohort(s) 1
Sample distribution


Cohort Short Name Cohort Full Name Previous/other/additional names (e.g. sub-cohorts)
MEC Multiethnic Cohort Study of Diet and Health