PGS Sample Set (PSS): PSS001093

Phenotype All individuals had cystic fibrosis with either 2 severe CFTR mutations and/or clinically diagnosed exocrine pancreatic insufficiency. Cases are individuals with cystic fibrosis related diabetes (CFRD).Phenotypes were obtained from extracted medical charts and CF Foundation Patient Registry through 2011. CFRD was defined by clinician diagnosis of diabetes plus insulin treatment for at least 1 year. The onset of CFRD was defined as the date at which insulin was started, if it was subsequently continued for at least 1 year. In approximately 50% of the participants, independent laboratory data (such as oral glucose tolerance test or hemoglobin A1c) were able to independently confirm the diagnosis of CFRD. Diabetes data were censored at the last clinic visit or date of solid organ transplant.
Sample Ancestry Not reported

Sample Numbers

Total number
591 individuals
Detailed numbers
204 cases (34.52%)
387 controls
54.82% Male samples
Age of Study Participants Mean : 22.7 years
Number of Cohort(s) 1
Sample distribution
Sample gender distribution


Cohort Short Name Cohort Full Name Previous/other/additional names (e.g. sub-cohorts)
JHU Johns Hopkins University