PGS Catalog - PGS000027 / Body Mass Index (Polygenic Score)

Study Identifiers	Sample Numbers	Sample Ancestry	Cohort(s)
GWAS Catalog: GCST002783 Europe PMC: 25673413	1,276 individuals	Hispanic or Latin American	NR
GWAS Catalog: GCST002783 Europe PMC: 25673413	236,781 individuals	European	NR
GWAS Catalog: GCST002783 Europe PMC: 25673413	887 individuals	African American or Afro-Caribbean	NR

Study Identifiers	Sample Numbers	Sample Ancestry	Cohort(s)	Phenotype Definitions & Methods	Age of Study Participants	Participant Follow-up Time	Additional Ancestry Description	Additional Sample/Cohort Information
—	119,951 individuals	European	UKB	—	—	—	—	UKB Phase 1

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance Metric ID (PPM)	PGS Sample Set ID (PSS)	Performance Source	Trait	PGS Effect Sizes (per SD change)	Classification Metrics	Other Metrics	Covariates Included in the Model	PGS Performance: Other Relevant Information
PPM000054	PSS000037\| European Ancestry\| 288,016 individuals	PGP000017 \| Khera AV et al. Cell (2019)	Reported Trait: Body mass index	β: 1.41	—	R²: 0.08526	First 10 genetic PCs	Beta is in units of kg/m^2
PPM001725	PSS000885\| European Ancestry\| 19,588 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between male siblings	OR: 2.21 [1.92, 2.54]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001726	PSS000886\| European Ancestry\| 21,499 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within female siblings	OR: 2.09 [1.74, 2.51]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001727	PSS000886\| European Ancestry\| 21,499 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between female siblings	OR: 2.13 [1.87, 2.43]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001728	PSS000887\| European Ancestry\| 26,323 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within male siblings	OR: 2.15 [1.91, 2.41]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001730	PSS000888\| European Ancestry\| 29,527 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within female siblings	OR: 1.87 [1.68, 2.09]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001731	PSS000888\| European Ancestry\| 29,527 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between female siblings	OR: 2.05 [1.89, 2.22]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001732	PSS000889\| European Ancestry\| 21,187 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within male siblings	OR: 2.0 [1.79, 2.23]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001733	PSS000889\| European Ancestry\| 21,187 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between male siblings	OR: 2.12 [1.96, 2.3]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001734	PSS000890\| European Ancestry\| 25,096 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within female siblings	OR: 2.0 [1.8, 2.21]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001735	PSS000890\| European Ancestry\| 25,096 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between female siblings	OR: 2.03 [1.88, 2.19]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001736	PSS000891\| European Ancestry\| 14,487 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within male siblings	OR: 1.9 [1.68, 2.14]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001769	PSS000911\| Greater Middle Eastern Ancestry\| 13,989 individuals	PGP000147 \| Thareja G et al. Nat Commun (2021) \|Ext.	Reported Trait: Body mass index	—	—	Pearson correlation coefficent (r): 0.22	—	—
PPM001737	PSS000891\| European Ancestry\| 14,487 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between male siblings	OR: 2.0 [1.83, 2.19]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001738	PSS000892\| European Ancestry\| 17,740 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within female siblings	OR: 1.72 [1.53, 1.93]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001739	PSS000892\| European Ancestry\| 17,740 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between female siblings	OR: 1.89 [1.74, 2.05]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001724	PSS000885\| European Ancestry\| 19,588 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity within male siblings	OR: 2.02 [1.66, 2.46]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM001729	PSS000887\| European Ancestry\| 26,323 individuals	PGP000141 \| Brandkvist M et al. PLoS Med (2020) \|Ext.	Reported Trait: Obesity between male siblings	OR: 2.15 [1.97, 2.34]	—	—	Sex, time of measurement, age, PCs (1-20), genotyping batch	2.07 million of the 2.1 milliion common variants (excluding those with insufficient quality of genotyping or imputation (r^2 < 0.8) in the HUNT cohort) were included in the polygenic score previously developed by Khera et al (2019).
PPM016747	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Flat foot	OR: 2.1 β: 0.7 (0.2)	—	—	—	—
PPM016596	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Vitamin deficiency	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016783	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Corns and callosities	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016784	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute pain	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016785	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abnormal glucose	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016570	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Myocardial infarction	OR: 2.5 β: 0.9 (0.1)	—	—	—	—
PPM016786	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic pain syndrome	OR: 2.1 β: 0.7 (0.2)	—	—	—	—
PPM016787	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute and chronic tonsillitis	OR: 1.8 β: 0.6 (0.2)	—	—	—	—
PPM016980	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Joint effusions	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016649	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Carbuncle and furuncle	OR: 3.7 β: 1.3 (0.2)	—	—	—	—
PPM016738	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Disorders of parathyroid gland	OR: 2.0 β: 0.7 (0.2)	—	—	—	—
PPM016739	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Disorders of adrenal glands	OR: 2.0 β: 0.7 (0.2)	—	—	—	—
PPM016740	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ingrowing nail	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016651	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gouty arthropathy	OR: 2.9 β: 1.1 (0.2)	—	—	—	—
PPM016652	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypoglycemia	OR: 3.1 β: 1.1 (0.2)	—	—	—	—
PPM016830	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Essential hypertension	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016831	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypertension	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016832	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetes mellitus	OR: 1.3 β: 0.3 (0.0)	—	—	—	—
PPM016833	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes	OR: 1.4 β: 0.3 (0.0)	—	—	—	—
PPM016835	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Obesity	OR: 1.8 β: 0.6 (0.0)	—	—	—	—
PPM016836	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016837	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthritis; localized	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016838	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hyperlipidemia	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016839	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Disorders of lipoid metabolism	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016653	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis, generalized	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM014877	PSS009917\| European Ancestry\| 832 individuals	PGP000349 \| Shi M et al. Circ Genom Precis Med (2022) \|Ext.	Reported Trait: Body mass index (last completed follow-up visit)	—	—	R²: 0.0729	—	—
PPM014878	PSS009916\| African Ancestry\| 369 individuals	PGP000349 \| Shi M et al. Circ Genom Precis Med (2022) \|Ext.	Reported Trait: Body mass index (last completed follow-up visit)	—	—	R²: 0.0256	—	—
PPM014880	PSS009917\| European Ancestry\| 832 individuals	PGP000349 \| Shi M et al. Circ Genom Precis Med (2022) \|Ext.	Reported Trait: Fasting plasma glucose (last completed follow-up visit)	β: 2.82 (0.87)	—	—	Age, sex, ancestry principal components, and baseline BMI	—
PPM014881	PSS009917\| European Ancestry\| 832 individuals	PGP000349 \| Shi M et al. Circ Genom Precis Med (2022) \|Ext.	Reported Trait: Systolic blood pressure (last completed follow-up visit)	β: 1.09 (0.52)	—	—	Age, sex, ancestry principal components, and baseline BMI	—
PPM014882	PSS009917\| European Ancestry\| 832 individuals	PGP000349 \| Shi M et al. Circ Genom Precis Med (2022) \|Ext.	Reported Trait: Obesity	HR: 1.26 [1.14, 1.38]	—	—	Sex, birth year, ancestry principal components, and baseline BMI	—
PPM014883	PSS009916\| African Ancestry\| 369 individuals	PGP000349 \| Shi M et al. Circ Genom Precis Med (2022) \|Ext.	Reported Trait: Obesity	HR: 1.11 [0.96, 1.38]	—	—	Sex, birth year, ancestry principal components, and baseline BMI	—
PPM014879	PSS009917\| European Ancestry\| 832 individuals	PGP000349 \| Shi M et al. Circ Genom Precis Med (2022) \|Ext.	Reported Trait: Body mass index (last completed follow-up visit)	β: 1.29 (0.22)	—	—	Age, sex, PCs, PRS, baseline BMI	—
PPM014945	PSS009938\| European Ancestry\| 6,064 individuals	PGP000363 \| Sapkota Y et al. Nat Med (2022) \|Ext.	Reported Trait: Overweight	—	—	Odds Ratio (OR, 10th vs. 1st decile): 2.74 [1.64, 4.57]	Cubic splines (five knots at 19.8, 24.0, 28.9, 34.9 and 46.9 years) of age at body mass index assessment, 10 genetic PCs	—
PPM014946	PSS009938\| European Ancestry\| 6,064 individuals	PGP000363 \| Sapkota Y et al. Nat Med (2022) \|Ext.	Reported Trait: Obesity	—	—	Odds Ratio (OR, 10th vs. 1st decile): 10.04 [5.92, 17.01]	Cubic splines (five knots at 19.8, 24.0, 28.9, 34.9 and 46.9 years) of age at body mass index assessment, 10 genetic PCs	—
PPM014947	PSS009938\| European Ancestry\| 6,064 individuals	PGP000363 \| Sapkota Y et al. Nat Med (2022) \|Ext.	Reported Trait: Severe obesity	—	—	Odds Ratio (OR, 10th vs. 1st decile): 53.05 [17.64, 159.54]	Cubic splines (five knots at 19.8, 24.0, 28.9, 34.9 and 46.9 years) of age at body mass index assessment, 10 genetic PCs	—
PPM014948	PSS009937\| African Ancestry\| 449 individuals	PGP000363 \| Sapkota Y et al. Nat Med (2022) \|Ext.	Reported Trait: Underweight	—	—	Odds Ratio (OR, 10th vs. 1st decile): 0.0 [0.0, 0.37]	Cubic splines (five knots at 19.8, 24.0, 28.9, 34.9 and 46.9 years) of age at body mass index assessment, 10 genetic PCs	—
PPM014950	PSS009937\| African Ancestry\| 449 individuals	PGP000363 \| Sapkota Y et al. Nat Med (2022) \|Ext.	Reported Trait: Obesity	—	—	Odds Ratio (OR, 10th vs. 1st decile): 5.92 [1.67, 20.96]	Cubic splines (five knots at 19.8, 24.0, 28.9, 34.9 and 46.9 years) of age at body mass index assessment, 10 genetic PCs	—
PPM014951	PSS009937\| African Ancestry\| 449 individuals	PGP000363 \| Sapkota Y et al. Nat Med (2022) \|Ext.	Reported Trait: Severe obesity	—	—	Odds Ratio (OR, 10th vs. 1st decile): 19.68 [2.87, 135.02]	Cubic splines (five knots at 19.8, 24.0, 28.9, 34.9 and 46.9 years) of age at body mass index assessment, 10 genetic PCs	—
PPM014949	PSS009937\| African Ancestry\| 449 individuals	PGP000363 \| Sapkota Y et al. Nat Med (2022) \|Ext.	Reported Trait: Overweight	—	—	Odds Ratio (OR, 10th vs. 1st decile): 3.53 [1.03, 12.09]	Cubic splines (five knots at 19.8, 24.0, 28.9, 34.9 and 46.9 years) of age at body mass index assessment, 10 genetic PCs	—
PPM016595	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Mixed hyperlipidemia	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM016535	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Obesity	OR: 26.7 β: 3.3 (0.1)	—	—	—	—
PPM016536	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Morbid obesity	OR: 77.0 β: 4.3 (0.1)	—	—	—	—
PPM016537	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes	OR: 6.8 β: 1.9 (0.1)	—	—	—	—
PPM016538	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetes mellitus	OR: 6.4 β: 1.9 (0.1)	—	—	—	—
PPM016539	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bariatric surgery	OR: 110.6 β: 4.7 (0.2)	—	—	—	—
PPM016540	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sleep apnea	OR: 6.5 β: 1.9 (0.1)	—	—	—	—
PPM016541	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Eating disorder	OR: 61.2 β: 4.1 (0.2)	—	—	—	—
PPM016542	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Obstructive sleep apnea	OR: 5.8 β: 1.8 (0.1)	—	—	—	—
PPM016543	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other chronic nonalcoholic liver disease	OR: 7.9 β: 2.1 (0.1)	—	—	—	—
PPM016544	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic liver disease and cirrhosis	OR: 7.1 β: 2.0 (0.1)	—	—	—	—
PPM016545	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypertension	OR: 3.7 β: 1.3 (0.1)	—	—	—	—
PPM016546	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Essential hypertension	OR: 3.6 β: 1.3 (0.1)	—	—	—	—
PPM016548	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Insulin pump user	OR: 7.7 β: 2.0 (0.1)	—	—	—	—
PPM016549	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes with neurological manifestations	OR: 7.3 β: 2.0 (0.1)	—	—	—	—
PPM016550	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Polyneuropathy in diabetes	OR: 6.9 β: 1.9 (0.1)	—	—	—	—
PPM016551	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 1 diabetes	OR: 5.1 β: 1.6 (0.1)	—	—	—	—
PPM016552	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes with renal manifestations	OR: 6.5 β: 1.9 (0.1)	—	—	—	—
PPM016553	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Edema	OR: 2.7 β: 1.0 (0.1)	—	—	—	—
PPM016554	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes with ophthalmic manifestations	OR: 8.2 β: 2.1 (0.2)	—	—	—	—
PPM016555	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis	OR: 2.4 β: 0.9 (0.1)	—	—	—	—
PPM016556	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of intestine	OR: 3.3 β: 1.2 (0.1)	—	—	—	—
PPM016557	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetic retinopathy	OR: 7.2 β: 2.0 (0.2)	—	—	—	—
PPM016559	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Coronary atherosclerosis	OR: 2.5 β: 0.9 (0.1)	—	—	—	—
PPM016560	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute renal failure	OR: 2.9 β: 1.1 (0.1)	—	—	—	—
PPM016561	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Congestive heart failure; nonhypertensive	OR: 2.7 β: 1.0 (0.1)	—	—	—	—
PPM016562	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis NOS	OR: 2.4 β: 0.9 (0.1)	—	—	—	—
PPM016563	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ischemic Heart Disease	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016564	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Renal failure	OR: 2.3 β: 0.9 (0.1)	—	—	—	—
PPM016565	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Shortness of breath	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016566	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypertensive heart and/or renal disease	OR: 2.4 β: 0.9 (0.1)	—	—	—	—
PPM016567	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gout	OR: 3.3 β: 1.2 (0.1)	—	—	—	—
PPM016568	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiomegaly	OR: 2.5 β: 0.9 (0.1)	—	—	—	—
PPM016571	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic venous insufficiency [CVI]	OR: 3.6 β: 1.3 (0.1)	—	—	—	—
PPM016572	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Panniculitis	OR: 31.2 β: 3.4 (0.4)	—	—	—	—
PPM016655	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Deep vein thrombosis	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016573	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Encounter for long-term (current) use of anticoagulants	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016574	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Fluid overload	OR: 3.5 β: 1.3 (0.1)	—	—	—	—
PPM016575	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Respiratory failure, insufficiency, arrest	OR: 2.6 β: 1.0 (0.1)	—	—	—	—
PPM016577	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hyperlipidemia	OR: 1.9 β: 0.7 (0.1)	—	—	—	—
PPM016578	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Heart failure with preserved ejection fraction [Diastolic heart failure]	OR: 3.5 β: 1.3 (0.1)	—	—	—	—
PPM016579	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gout and other crystal arthropathies	OR: 2.8 β: 1.0 (0.1)	—	—	—	—
PPM016746	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Fasciitis	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016840	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sleep apnea	OR: 1.4 β: 0.4 (0.0)	—	—	—	—
PPM016841	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypercholesterolemia	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016285	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: BMI	—	—	R²: 0.0747	—	—
PPM016582	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Depression	OR: 1.9 β: 0.7 (0.1)	—	—	—	—
PPM016583	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetes type 2 with peripheral circulatory disorders	OR: 7.0 β: 1.9 (0.2)	—	—	—	—
PPM016584	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ventral hernia	OR: 5.2 β: 1.6 (0.2)	—	—	—	—
PPM016585	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Disorders of lipoid metabolism	OR: 1.9 β: 0.6 (0.1)	—	—	—	—
PPM016586	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Mood disorders	OR: 1.9 β: 0.6 (0.1)	—	—	—	—
PPM016587	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pulmonary heart disease	OR: 2.5 β: 0.9 (0.1)	—	—	—	—
PPM016588	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gastrojejunal ulcer	OR: 61.0 β: 4.1 (0.4)	—	—	—	—
PPM016589	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic pulmonary heart disease	OR: 2.8 β: 1.0 (0.1)	—	—	—	—
PPM016590	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Dysmetabolic syndrome X	OR: 8.0 β: 2.1 (0.2)	—	—	—	—
PPM016591	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Asthma	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016592	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic ulcer of skin	OR: 2.6 β: 1.0 (0.1)	—	—	—	—
PPM016593	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Superficial cellulitis and abscess	OR: 1.9 β: 0.7 (0.1)	—	—	—	—
PPM016597	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other venous embolism and thrombosis	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016598	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Postoperative infection	OR: 3.0 β: 1.1 (0.1)	—	—	—	—
PPM016599	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Localized adiposity	OR: 13.0 β: 2.6 (0.3)	—	—	—	—
PPM016600	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pulmonary collapse; interstitial and compensatory emphysema	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016601	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthritis; localized	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016602	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Respiratory failure	OR: 2.8 β: 1.0 (0.1)	—	—	—	—
PPM016603	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other dyspnea	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016604	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholelithiasis and cholecystitis	OR: 2.4 β: 0.9 (0.1)	—	—	—	—
PPM016605	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of the kidney and ureters	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016607	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atrial fibrillation	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016608	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholelithiasis	OR: 2.4 β: 0.9 (0.1)	—	—	—	—
PPM016609	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Incisional hernia	OR: 4.5 β: 1.5 (0.2)	—	—	—	—
PPM016610	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bacterial infection NOS	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016611	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atrial fibrillation and flutter	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016612	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis, localized, primary	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM016613	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Septicemia	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016614	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other peripheral nerve disorders	OR: 1.9 β: 0.6 (0.1)	—	—	—	—
PPM016615	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic ulcer of leg or foot	OR: 2.8 β: 1.0 (0.1)	—	—	—	—
PPM016617	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Wheezing	OR: 2.6 β: 1.0 (0.1)	—	—	—	—
PPM016618	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Dependence on respirator [Ventilator] or supplemental oxygen	OR: 4.6 β: 1.5 (0.2)	—	—	—	—
PPM016619	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Heart failure	OR: 2.5 β: 0.9 (0.1)	—	—	—	—
PPM016620	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Swelling of limb	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016621	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic airway obstruction	OR: 1.9 β: 0.6 (0.1)	—	—	—	—
PPM016622	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nephritis and nephropathy in diseases classified elsewhere	OR: 3.8 β: 1.3 (0.2)	—	—	—	—
PPM016623	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pulmonary congestion and hypostasis	OR: 2.6 β: 0.9 (0.1)	—	—	—	—
PPM016624	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Arthropathy	OR: 1.9 β: 0.6 (0.1)	—	—	—	—
PPM016625	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Vitamin D deficiency	OR: 1.9 β: 0.6 (0.1)	—	—	—	—
PPM016626	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Respiratory abnormalities	OR: 2.4 β: 0.9 (0.1)	—	—	—	—
PPM016627	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic obstructive asthma	OR: 3.4 β: 1.2 (0.2)	—	—	—	—
PPM016628	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other arthropathies	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016629	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Angina pectoris	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016630	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cellulitis and abscess of trunk	OR: 3.1 β: 1.1 (0.2)	—	—	—	—
PPM016632	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Proteinuria	OR: 2.8 β: 1.0 (0.1)	—	—	—	—
PPM016633	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acquired acanthosis nigricans	OR: 16.3 β: 2.8 (0.4)	—	—	—	—
PPM016634	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Primary/intrinsic cardiomyopathies	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM016635	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cirrhosis of liver without mention of alcohol	OR: 4.0 β: 1.4 (0.2)	—	—	—	—
PPM016636	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Decubitus ulcer	OR: 3.1 β: 1.1 (0.2)	—	—	—	—
PPM016637	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Iron deficiency anemias	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016638	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic Kidney Disease, Stage III	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016639	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other forms of chronic heart disease	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016640	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiomyopathy	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016641	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypertensive heart disease	OR: 2.1 β: 0.8 (0.1)	—	—	—	—
PPM016642	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Unstable angina (intermediate coronary syndrome)	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016643	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spinal stenosis of lumbar region	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016644	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypoventilation	OR: 3.7 β: 1.3 (0.2)	—	—	—	—
PPM016646	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypercholesterolemia	OR: 1.6 β: 0.4 (0.1)	—	—	—	—
PPM016647	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Candidiasis of skin and nails	OR: 3.8 β: 1.3 (0.2)	—	—	—	—
PPM016648	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Obstructive chronic bronchitis	OR: 2.6 β: 1.0 (0.2)	—	—	—	—
PPM016650	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 1 diabetes with neurological manifestations	OR: 4.6 β: 1.5 (0.2)	—	—	—	—
PPM016656	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Iron deficiency anemias, unspecified or not due to blood loss	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016657	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Umbilical hernia	OR: 3.1 β: 1.1 (0.2)	—	—	—	—
PPM016658	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Polycystic ovaries	OR: 7.0 β: 2.0 (0.3)	—	—	—	—
PPM016659	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Staphylococcus infections	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016660	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Paroxysmal ventricular tachycardia	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016661	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other symptoms of respiratory system	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016662	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute bronchitis and bronchiolitis	OR: 1.7 β: 0.5 (0.1)	—	—	—	—
PPM016663	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abnormal function study of cardiovascular system	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016664	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diseases of esophagus	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016666	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteomyelitis	OR: 2.9 β: 1.1 (0.2)	—	—	—	—
PPM016667	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nephritis and nephropathy without mention of glomerulonephritis	OR: 2.4 β: 0.9 (0.2)	—	—	—	—
PPM016668	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Renal failure	OR: 2.3 β: 0.8 (0.1)	—	—	—	—
PPM016669	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other specified erythematous conditions	OR: 2.6 β: 1.0 (0.2)	—	—	—	—
PPM016670	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Megaloblastic anemia	OR: 3.2 β: 1.1 (0.2)	—	—	—	—
PPM016671	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic bronchitis	OR: 2.1 β: 0.8 (0.1)	—	—	—	—
PPM016672	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypothyroidism	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016673	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Portal hypertension	OR: 4.8 β: 1.6 (0.3)	—	—	—	—
PPM016674	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spinal stenosis	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016676	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Calcaneal spur; Exostosis	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM016677	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Shock	OR: 2.7 β: 1.0 (0.2)	—	—	—	—
PPM016678	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Primary pulmonary hypertension	OR: 3.3 β: 1.2 (0.2)	—	—	—	—
PPM016680	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bursitis	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016681	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hyperglyceridemia	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM016682	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac pacemaker/device in situ	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016683	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac defibrillator in situ	OR: 2.6 β: 1.0 (0.2)	—	—	—	—
PPM016684	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Vitamin B-complex deficiencies	OR: 2.3 β: 0.8 (0.2)	—	—	—	—
PPM016685	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Non-healing surgical wound	OR: 4.6 β: 1.5 (0.3)	—	—	—	—
PPM016686	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Orthopnea	OR: 5.7 β: 1.7 (0.3)	—	—	—	—
PPM016687	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypothyroidism	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016688	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholelithiasis with other cholecystitis	OR: 2.6 β: 0.9 (0.2)	—	—	—	—
PPM016689	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gastroesophageal reflux disease	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016690	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Intestinal malabsorption (non-celiac)	OR: 3.2 β: 1.2 (0.2)	—	—	—	—
PPM016691	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nephritis; nephrosis; renal sclerosis	OR: 1.9 β: 0.7 (0.1)	—	—	—	—
PPM016692	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Benign neoplasm of adrenal gland	OR: 6.1 β: 1.8 (0.3)	—	—	—	—
PPM016693	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Esophagitis, Gastroesophageal reflux disease and related diseases	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016694	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteomyelitis, periostitis, and other infections involving bone	OR: 2.4 β: 0.9 (0.2)	—	—	—	—
PPM016695	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Infection/inflammation of internal prosthetic device; implant; and graft	OR: 2.1 β: 0.8 (0.1)	—	—	—	—
PPM016696	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ill-defined descriptions and complications of heart disease	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016697	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac conduction disorders	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016699	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sleep disorders	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016700	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute pulmonary heart disease	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016701	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac pacemaker in situ	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016702	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Left bundle branch block	OR: 2.2 β: 0.8 (0.2)	—	—	—	—
PPM016703	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Asthma with exacerbation	OR: 2.1 β: 0.7 (0.2)	—	—	—	—
PPM016704	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Dermatophytosis	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016705	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cellulitis and abscess of foot, toe	OR: 2.5 β: 0.9 (0.2)	—	—	—	—
PPM016706	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other vitamin B12 deficiency anemia	OR: 3.4 β: 1.2 (0.3)	—	—	—	—
PPM016707	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sinoatrial node dysfunction (Bradycardia)	OR: 2.1 β: 0.7 (0.2)	—	—	—	—
PPM016708	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Malignant neoplasm of uterus	OR: 3.9 β: 1.4 (0.3)	—	—	—	—
PPM016709	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Coagulation defects	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016711	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Intervertebral disc disorders	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016712	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic venous hypertension	OR: 6.1 β: 1.8 (0.4)	—	—	—	—
PPM016713	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Dermatophytosis of nail	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016714	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic kidney disease, Stage I or II	OR: 2.1 β: 0.8 (0.2)	—	—	—	—
PPM016715	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Phlebitis and thrombophlebitis	OR: 1.9 β: 0.7 (0.1)	—	—	—	—
PPM016716	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Joint effusions	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016717	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic ulcer of unspecified site	OR: 2.3 β: 0.8 (0.2)	—	—	—	—
PPM016718	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other deficiency anemia	OR: 2.0 β: 0.7 (0.2)	—	—	—	—
PPM016719	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hidradenitis	OR: 6.4 β: 1.9 (0.4)	—	—	—	—
PPM016720	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pain	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016721	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Difficulty in walking	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016722	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Dermatophytosis / Dermatomycosis	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016724	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abdominal hernia	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016725	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Displacement of intervertebral disc	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016726	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ovarian dysfunction	OR: 3.3 β: 1.2 (0.3)	—	—	—	—
PPM016727	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Neuralgia, neuritis, and radiculitis	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016728	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Postphlebitic syndrome	OR: 6.8 β: 1.9 (0.4)	—	—	—	—
PPM016729	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nonspecific chest pain	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016730	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Varicose veins of lower extremity	OR: 1.7 β: 0.5 (0.1)	—	—	—	—
PPM016731	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Complication of internal orthopedic device	OR: 2.0 β: 0.7 (0.2)	—	—	—	—
PPM016732	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pulmonary embolism and infarction, acute	OR: 1.9 β: 0.7 (0.2)	—	—	—	—
PPM016733	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other hypertensive complications	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016734	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atrial flutter	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016736	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Athlete’s foot	OR: 1.8 β: 0.6 (0.1)	—	—	—	—
PPM016737	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholecystitis without cholelithiasis	OR: 2.2 β: 0.8 (0.2)	—	—	—	—
PPM016741	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other local infections of skin and subcutaneous tissue	OR: 1.7 β: 0.5 (0.1)	—	—	—	—
PPM016742	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic pain	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016743	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Arrhythmia (cardiac) NOS	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016744	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac dysrhythmias	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016745	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bronchitis	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016748	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Endometrial hyperplasia	OR: 3.3 β: 1.2 (0.3)	—	—	—	—
PPM016750	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nonrheumatic aortic valve disorders	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016751	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac arrest and ventricular fibrillation	OR: 2.2 β: 0.8 (0.2)	—	—	—	—
PPM016752	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Dislocation	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016753	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Degeneration of intervertebral disc	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016754	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Barrett's esophagus	OR: 2.6 β: 0.9 (0.2)	—	—	—	—
PPM016755	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Back pain	OR: 1.3 β: 0.2 (0.1)	—	—	—	—
PPM016756	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Disorders of sweat glands	OR: 2.5 β: 0.9 (0.2)	—	—	—	—
PPM016758	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atherosclerotic cardiovascular disease	OR: 2.0 β: 0.7 (0.2)	—	—	—	—
PPM016759	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spondylosis and allied disorders	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016760	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other abnormal blood chemistry	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016761	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Restless legs syndrome	OR: 1.9 β: 0.7 (0.2)	—	—	—	—
PPM016762	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Synovitis and tenosynovitis	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016763	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac arrest	OR: 2.4 β: 0.9 (0.2)	—	—	—	—
PPM016764	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Symptoms and disorders of the joints	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016765	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Methicillin resistant Staphylococcus aureus	OR: 2.4 β: 0.9 (0.2)	—	—	—	—
PPM016766	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hyperparathyroidism	OR: 1.9 β: 0.7 (0.2)	—	—	—	—
PPM016767	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Varicose veins	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016768	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spondylosis without myelopathy	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016770	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Arthropathy associated with other disorders classified elsewhere	OR: 3.4 β: 1.2 (0.3)	—	—	—	—
PPM016771	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Internal derangement of knee	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016772	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Noninfectious disorders of lymphatic channels	OR: 2.1 β: 0.7 (0.2)	—	—	—	—
PPM016773	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic tonsillitis and adenoiditis	OR: 2.2 β: 0.8 (0.2)	—	—	—	—
PPM016774	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Secondary/extrinsic cardiomyopathies	OR: 1.9 β: 0.6 (0.2)	—	—	—	—
PPM016775	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Infective connective tissue disorders	OR: 5.2 β: 1.6 (0.5)	—	—	—	—
PPM016776	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other abnormal glucose	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016777	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abnormal coagulation profile	OR: 1.7 β: 0.5 (0.2)	—	—	—	—
PPM016778	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Elevated sedimentation rate	OR: 2.3 β: 0.8 (0.3)	—	—	—	—
PPM016779	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spondylosis with myelopathy	OR: 2.0 β: 0.7 (0.2)	—	—	—	—
PPM016780	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acquired foot deformities	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016781	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Adrenal hyperfunction	OR: 3.0 β: 1.1 (0.3)	—	—	—	—
PPM016788	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of pancreatic internal secretion	OR: 2.3 β: 0.8 (0.3)	—	—	—	—
PPM016789	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute sinusitis	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016790	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Rupture of tendon, nontraumatic	OR: 1.8 β: 0.6 (0.2)	—	—	—	—
PPM016791	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hemorrhagic disorder due to intrinsic circulating anticoagulants	OR: 2.2 β: 0.8 (0.3)	—	—	—	—
PPM016792	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sciatica	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016793	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Urinary incontinence	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016794	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Postlaminectomy syndrome	OR: 2.4 β: 0.9 (0.3)	—	—	—	—
PPM016795	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Dysthymic disorder	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016796	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diverticulitis	OR: 1.6 β: 0.5 (0.2)	—	—	—	—
PPM016798	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Precordial pain	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016799	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cushing's syndrome	OR: 3.7 β: 1.3 (0.4)	—	—	—	—
PPM016800	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atrioventricular block	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016801	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Urinary calculus	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016802	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypersomnia	OR: 1.8 β: 0.6 (0.2)	—	—	—	—
PPM016803	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Otitis externa	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016804	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Retinal edema	OR: 2.2 β: 0.8 (0.3)	—	—	—	—
PPM016805	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Myopathy	OR: 1.8 β: 0.6 (0.2)	—	—	—	—
PPM016806	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cellulitis and abscess of fingers/toes	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM016808	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hirsutism	OR: 2.4 β: 0.9 (0.3)	—	—	—	—
PPM016809	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Suppurative and unspecified otitis media	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016810	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abnormal electrocardiogram	OR: 1.3 β: 0.2 (0.1)	—	—	—	—
PPM016811	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of soft tissues	OR: 1.6 β: 0.5 (0.2)	—	—	—	—
PPM016812	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Psoriasis	OR: 1.6 β: 0.5 (0.2)	—	—	—	—
PPM016813	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diaphragmatic hernia	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016814	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other symptoms involving abdomen and pelvis	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016815	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of lipoid metabolism	OR: 1.7 β: 0.5 (0.2)	—	—	—	—
PPM016816	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Intervertebral disc disorder with myelopathy	OR: 2.3 β: 0.8 (0.3)	—	—	—	—
PPM016817	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Psoriasis vulgaris	OR: 1.6 β: 0.5 (0.2)	—	—	—	—
PPM016818	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Otitis media	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016819	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetes insipidus	OR: 4.3 β: 1.5 (0.6)	—	—	—	—
PPM016820	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pilonidal cyst	OR: 3.7 β: 1.3 (0.5)	—	—	—	—
PPM016822	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acquired spondylolisthesis	OR: 1.6 β: 0.4 (0.2)	—	—	—	—
PPM016823	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Rotator cuff (capsule) sprain	OR: 1.5 β: 0.4 (0.2)	—	—	—	—
PPM016824	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Posttraumatic stress disorder	OR: 1.9 β: 0.6 (0.2)	—	—	—	—
PPM016825	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other nondiabetic retinopathy	OR: 1.7 β: 0.5 (0.2)	—	—	—	—
PPM016826	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other alveolar and parietoalveolar pneumonopathy	OR: 2.0 β: 0.7 (0.3)	—	—	—	—
PPM016827	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Peripheral enthesopathies and allied syndromes	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM016828	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Major depressive disorder	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016829	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Personality disorders	OR: 1.7 β: 0.5 (0.2)	—	—	—	—
PPM016843	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sleep disorders	OR: 1.3 β: 0.3 (0.0)	—	—	—	—
PPM016844	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other peripheral nerve disorders	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016845	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholelithiasis and cholecystitis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016846	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016847	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other chronic ischemic heart disease, unspecified	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016848	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis, localized, primary	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016849	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholelithiasis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016850	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic airway obstruction	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016851	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Angina pectoris	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016852	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Renal failure	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016854	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypothyroidism	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016855	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac dysrhythmias	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016856	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Myocardial infarction	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016857	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Coronary atherosclerosis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016858	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atrial fibrillation and flutter	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016859	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis, generalized	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016860	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic renal failure	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016861	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bacterial infection	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016863	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 1 diabetes	OR: 1.3 β: 0.3 (0.0)	—	—	—	—
PPM016864	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Esophagitis, GERD and related diseases	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016865	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute renal failure	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016866	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic ulcer of leg or foot	OR: 1.5 β: 0.4 (0.0)	—	—	—	—
PPM016867	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diseases of esophagus	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016868	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholelithiasis with other cholecystitis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016869	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Umbilical hernia	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016871	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Shortness of breath	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016872	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other symptoms of respiratory system	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016873	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diaphragmatic hernia	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016874	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes with neurological manifestations	OR: 1.7 β: 0.5 (0.0)	—	—	—	—
PPM016875	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of intestine	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016876	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic ulcer of skin	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016877	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic liver disease and cirrhosis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016878	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Respiratory failure	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016879	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pulmonary heart disease	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016880	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic bronchitis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016882	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Unstable angina (intermediate coronary syndrome)	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016883	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Major depressive disorder	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016884	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Depression	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016885	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic Kidney Disease, Stage III	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016886	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Heart failure NOS	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016887	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiomegaly	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016888	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Obstructive chronic bronchitis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016889	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetic retinopathy	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016981	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Respiratory abnormalities	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016890	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other chronic nonalcoholic liver disease	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016891	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abdominal hernia	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016893	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gout	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016894	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes with ophthalmic manifestations	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016895	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gout and other crystal arthropathies	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016896	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: GERD	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016897	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Postoperative infection	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016898	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Iron deficiency anemias	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016899	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Staphylococcus infections	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016900	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spondylosis and allied disorders	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016901	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ventral hernia	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016902	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Mood disorders	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016903	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Edema	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016904	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spondylosis without myelopathy	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016905	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Intervertebral disc disorders	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016906	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Congestive heart failure	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016908	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute pulmonary heart disease	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016909	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cholecystitis without cholelithiasis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016910	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetes type 2 with peripheral circulatory disorders	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016911	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Psoriasis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016912	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of synovium, tendon, and bursa	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016913	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spinal stenosis	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016914	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Psoriasis vulgaris	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016915	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Rheumatoid arthritis and other inflammatory polyarthropathies	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016916	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Precordial pain	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016917	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nonspecific chest pain	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016918	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Back pain	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016919	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nonrheumatic aortic valve disorders	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016922	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Degeneration of intervertebral disc	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016923	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Symptoms and disorders of the joints	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016924	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Septicemia	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016926	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Peritoneal adhesions (postoperative) (postinfection)	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016927	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other local infections of skin and subcutaneous tissue	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016928	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Superficial cellulitis and abscess	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016929	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypertensive chronic kidney disease	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016930	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Varicose veins of lower extremity	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016931	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Phlebitis and thrombophlebitis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016932	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Varicose veins	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016933	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Urinary incontinence	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016935	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypoventilation	OR: 2.0 β: 0.7 (0.1)	—	—	—	—
PPM016936	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Liver abscess and sequelae of chronic liver disease	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016937	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other forms of chronic heart disease	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016938	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Disorders of sweat glands	OR: 1.3 β: 0.3 (0.0)	—	—	—	—
PPM016939	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac conduction disorders	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016940	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hidradenitis	OR: 1.7 β: 0.5 (0.1)	—	—	—	—
PPM016941	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Noninfectious disorders of lymphatic channels	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016942	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other deficiency anemia	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016943	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Megaloblastic anemia	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016944	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Varicose veins of lower extremity, symptomtic	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016945	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic pulmonary heart disease	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016946	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Calcaneal spur; Exostosis NOS	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016948	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiomyopathy	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016949	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Displacement of intervertebral disc	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016950	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Urinary calculus	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016951	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Primary/intrinsic cardiomyopathies	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016952	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Rupture of tendon, nontraumatic	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016953	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abnormal glucose	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016954	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Vitamin deficiency	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016955	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of pancreatic internal secretion	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016956	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other specified erythematous conditions	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016957	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypoglycemia	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016958	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Synovitis and tenosynovitis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016959	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sciatica	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016961	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Incisional hernia	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016962	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Vitamin B-complex deficiencies	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016963	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Fluid overload	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016964	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Renal failure NOS	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016965	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acquired foot deformities	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016966	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ingrowing nail	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016967	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acquired spondylolisthesis	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016968	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Malignant neoplasm of uterus	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016969	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other alveolar and parietoalveolar pneumonopathy	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016970	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Nephritis; nephrosis; renal sclerosis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016971	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bundle branch block	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016972	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atrioventricular block	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016973	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Otitis externa	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016975	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Difficulty in walking	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016976	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pulmonary collapse; interstitial and compensatory emphysema	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016977	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cirrhosis of liver without mention of alcohol	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016978	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Decubitus ulcer	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016979	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cellulitis and abscess of trunk	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016982	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Polycystic ovaries	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016984	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic venous insufficiency	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016985	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other venous embolism and thrombosis	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016986	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Mixed hyperlipidemia	OR: 1.4 β: 0.4 (0.1)	—	—	—	—
PPM016987	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of the kidney and ureters	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016988	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Barrett's esophagus	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016989	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other abnormal blood chemistry	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM016990	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other arthropathies	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016991	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other abnormal glucose	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM016992	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Complication of internal orthopedic device	OR: 1.3 β: 0.2 (0.1)	—	—	—	—
PPM016993	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of soft tissues	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016994	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pilonidal cyst	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM016996	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Localized adiposity	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016997	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Benign neoplasm of other endocrine glands and related structures	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016998	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac arrest and ventricular fibrillation	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016999	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ovarian dysfunction	OR: 1.3 β: 0.2 (0.1)	—	—	—	—
PPM017000	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Swelling of limb	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM017001	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 1 diabetes with neurological manifestations	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM017002	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetes type 1 with peripheral circulatory disorders	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM017003	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Benign neoplasm of adrenal gland	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM017004	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Wheezing	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017005	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Disorders of adrenal glands	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017006	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Portal hypertension	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM017007	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteomyelitis	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017008	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Suppurative and unspecified otitis media	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017009	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteomyelitis, periostitis, and other infections involving bone	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017010	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cardiac arrest	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017011	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Endometrial hyperplasia	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017012	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Left bundle branch block	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017013	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Acute and chronic tonsillitis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017014	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Arthropathy associated with neurological disorders	OR: 1.5 β: 0.4 (0.1)	—	—	—	—
PPM017015	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Otitis media	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017016	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Atrial fibrillation	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017017	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sinoatrial node dysfunction (Bradycardia)	OR: 1.1 β: 0.1 (0.1)	—	—	—	—
PPM017018	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cancer of kidney and renal pelvis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017019	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Infective connective tissue disorders	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM017020	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other symptoms involving abdomen and pelvis	OR: 1.0 β: 0.0 (0.0)	—	—	—	—
PPM017021	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bronchitis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017022	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic tonsillitis and adenoiditis	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM017024	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Flat foot	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017025	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Myopathy	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017026	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gouty arthropathy	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017027	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bariatric surgery	OR: 1.6 β: 0.4 (0.2)	—	—	—	—
PPM017028	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Coagulation defects	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016534	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Overweight, obesity and other hyperalimentation	OR: 16.4 β: 2.8 (0.1)	—	—	—	—
PPM016547	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Gastrointestinal complications	OR: 12.3 β: 2.5 (0.1)	—	—	—	—
PPM016558	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Congestive heart failure (CHF) NOS	OR: 2.9 β: 1.1 (0.1)	—	—	—	—
PPM016569	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Abnormal weight gain	OR: 3.8 β: 1.3 (0.1)	—	—	—	—
PPM016576	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cellulitis and abscess of leg, except foot	OR: 3.2 β: 1.2 (0.1)	—	—	—	—
PPM016580	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic renal failure [	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM016581	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypertensive chronic kidney disease	OR: 2.4 β: 0.9 (0.1)	—	—	—	—
PPM016594	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Heart failure with reduced ejection fraction [Systolic or combined heart failure]	OR: 3.0 β: 1.1 (0.1)	—	—	—	—
PPM016606	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other chronic ischemic heart disease, unspecified	OR: 2.2 β: 0.8 (0.1)	—	—	—	—
PPM016616	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016631	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Encounter for long-term (current) use of aspirin	OR: 2.1 β: 0.7 (0.1)	—	—	—	—
PPM016645	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic Kidney Disease, Stage IV	OR: 2.7 β: 1.0 (0.2)	—	—	—	—
PPM016654	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Liver abscess and sequelae of chronic liver disease	OR: 3.7 β: 1.3 (0.2)	—	—	—	—
PPM016665	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Peritoneal adhesions (postoperative) (postinfection)	OR: 3.2 β: 1.2 (0.2)	—	—	—	—
PPM016675	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Bundle branch block	OR: 1.9 β: 0.7 (0.1)	—	—	—	—
PPM016679	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Osteoarthrosis involving more than one site, but not specified as generalized	OR: 2.5 β: 0.9 (0.2)	—	—	—	—
PPM016698	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Arthropathy associated with neurological disorders	OR: 8.6 β: 2.2 (0.4)	—	—	—	—
PPM016710	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hereditary and idiopathic peripheral neuropathy	OR: 1.7 β: 0.5 (0.1)	—	—	—	—
PPM016723	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Thoracic or lumbosacral neuritis or radiculitis, unspecified	OR: 1.6 β: 0.5 (0.1)	—	—	—	—
PPM016735	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Varicose veins of lower extremity, symptomatic	OR: 1.9 β: 0.7 (0.2)	—	—	—	—
PPM016749	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Phlebitis and thrombophlebitis of lower extremities	OR: 2.0 β: 0.7 (0.2)	—	—	—	—
PPM016757	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Sleep related movement disorders	OR: 1.8 β: 0.6 (0.2)	—	—	—	—
PPM016769	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Other disorders of synovium, tendon, and bursa	OR: 1.3 β: 0.3 (0.1)	—	—	—	—
PPM016782	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Diabetes type 1 with peripheral circulatory disorders	OR: 3.9 β: 1.4 (0.4)	—	—	—	—
PPM016797	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cancer of kidney and renal pelvis	OR: 1.9 β: 0.7 (0.2)	—	—	—	—
PPM016807	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Benign neoplasm of other endocrine glands and related structures	OR: 1.7 β: 0.6 (0.2)	—	—	—	—
PPM016821	PSS010097\| Multi-ancestry (including European)\| 405,432 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Rheumatoid arthritis and other inflammatory polyarthropathies	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016834	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Overweight, obesity and other hyperalimentation	OR: 1.8 β: 0.6 (0.0)	—	—	—	—
PPM016842	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Ischemic Heart Disease	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016853	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypothyroidism NOS	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016862	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Internal derangement of knee	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016870	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Congestive heart failure; nonhypertensive	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016881	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Respiratory failure, insufficiency, arrest	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016892	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Iron deficiency anemias, unspecified or not due to blood loss	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016907	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Pulmonary embolism and infarction, acute	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016920	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Peripheral enthesopathies and allied syndromes	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016921	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Spinal stenosis of lumbar region	OR: 1.2 β: 0.1 (0.0)	—	—	—	—
PPM016925	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hypertensive heart and/or renal disease	OR: 1.2 β: 0.2 (0.0)	—	—	—	—
PPM016934	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Phlebitis and thrombophlebitis of lower extremities	OR: 1.3 β: 0.2 (0.0)	—	—	—	—
PPM016947	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Thoracic or lumbosacral neuritis or radiculitis, unspecified	OR: 1.1 β: 0.1 (0.0)	—	—	—	—
PPM016960	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Type 2 diabetes with renal manifestations	OR: 1.4 β: 0.3 (0.1)	—	—	—	—
PPM016974	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Primary pulmonary hypertension	OR: 1.3 β: 0.2 (0.1)	—	—	—	—
PPM016983	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Chronic Kidney Disease, Stage IV	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM016995	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Hereditary and idiopathic peripheral neuropathy	OR: 1.2 β: 0.2 (0.1)	—	—	—	—
PPM017023	PSS010096\| Multi-ancestry (including European)\| 65,174 individuals	PGP000416 \| Robinson JR et al. Obesity (Silver Spring) (2022) \|Ext.	Reported Trait: Cellulitis and abscess of fingers/toes	OR: 1.1 β: 0.1 (0.0)	—	—	—	—

Evaluated Samples

PGS Sample Set ID (PSS)	Phenotype Definitions and Methods	Participant Follow-up Time	Sample Numbers	Age of Study Participants	Sample Ancestry	Additional Ancestry Description	Cohort(s)	Additional Sample/Cohort Information
PSS000892	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	17,740 individuals [ 17,740 cases ] , 0.0 % Male samples	Mean = 58.9 years Sd = 11.9 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)
PSS009916	—	—	369 individuals, 38.8 % Male samples	Mean = 44.6 years	African unspecified	—	BHS	—
PSS009917	—	—	832 individuals, 45.1 % Male samples	Mean = 45.4 years	European	—	BHS	—
PSS000911	—	—	13,989 individuals	—	Greater Middle Eastern (Middle Eastern, North African or Persian) (Qatari)	—	QBB	—
PSS009937	—	—	449 individuals, 48.3 % Male samples	—	African American or Afro-Caribbean	—	NR	—
PSS009938	—	—	6,064 individuals, 47.9 % Male samples	—	European	—	NR	—
PSS000037	—	—	288,016 individuals, 45.0 % Male samples	—	European	—	UKB	—
PSS010096	—	—	52,760 individuals	—	European	—	UKB	—
PSS010096	—	—	11,323 individuals	—	African unspecified (Black)	—	UKB	—
PSS010096	—	—	1,091 individuals	—	Asian unspecified	—	UKB	—
PSS010097	—	—	390,459 individuals	—	European	—	eMERGE	—
PSS010097	—	—	3,018 individuals	—	African unspecified (Black)	—	eMERGE	—
PSS010097	—	—	8,169 individuals	—	Asian unspecified	—	eMERGE	—
PSS010097	—	—	3,786 individuals	—	Other	—	eMERGE	—
PSS000885	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	19,588 individuals [ 19,588 cases ] , 100.0 % Male samples	Mean = 42.4 years Sd = 12.6 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)
PSS000886	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	21,499 individuals [ 21,499 cases ] , 0.0 % Male samples	Mean = 42.6 years Sd = 12.8 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)
PSS000887	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	26,323 individuals [ 26,336 cases ] , 100.0 % Male samples	Mean = 47.6 years Sd = 16.1 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)
PSS000888	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	29,527 individuals [ 29,545 cases ] , 0.0 % Male samples	Mean = 47.1 years Sd = 16.5 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)
PSS000889	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	21,187 individuals [ 21,192 cases ] , 100.0 % Male samples	Mean = 52.3 years Sd = 14.5 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)
PSS000890	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	25,096 individuals [ 25,108 cases ] , 0.0 % Male samples	Mean = 51.2 years Sd = 15.0 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)
PSS000891	Body mass index (BMI) measurements were standardized with weight measured to the nearest half kilogram with the participants wearing light clothes and no shoes, and height was measured to the nearest centimeter. BMI was calculated using the formula weight in kilograms per meter squared. As defined by the World Health Organization (WHO), the authors rrefer to overweight as having BMI greater than or equal to 25 and obesity as having BMI greater than or equal to 30. Severe obesity was defined as having BMI greater than or equal to 35.	—	14,487 individuals [ 14,487 cases ] , 100.0 % Male samples	Mean = 60.2 years Sd = 11.5 years	European	—	HUNT	number o cases = number of observations (more than 1 pp)

Predicted Trait
Reported Trait	Body Mass Index
Mapped Trait(s)	body mass index (EFO_0004340)

Score Construction
PGS Name	GPS_BMI
Development Method
Name	LDpred
Parameters	ρ = 0.03; LD reference panel = 503 European samples from 1000 Genomes phase 3
Variants
Original Genome Build	hg19
Number of Variants	2,100,302
Effect Weight Type	NR

PGS Source
PGS Catalog Publication (PGP) ID	PGP000017
Citation (link to publication)	Khera AV et al. Cell (2019)

Ancestry Distribution
Source of Variant Associations (GWAS)	European: 99.1% Hispanic or Latin American: 0.5% African: 0.4% 238,944 individuals (100%)
Score Development/Training	European: 100% 119,951 individuals (100%)
PGS Evaluation	European: 68.8% African: 12.5% Multi-ancestry (including European): 12.5% European African Additional Asian Ancestries Additional Diverse Ancestries Greater Middle Eastern: 6.2% 16 Sample Sets

Polygenic Score (PGS) ID: PGS000027

Score Details

Development Samples

Source of Variant Associations (GWAS)

Score Development/Training

Performance Metrics

Evaluated Samples