Polygenic Score (PGS) ID: PGS001978

Predicted Trait
Reported Trait Sleep duration
Mapped Trait(s) sleep duration (EFO_0005271)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_log_sleep
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 40,037
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010699 PSS009466|
European Ancestry|
19,860 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1275 [0.1138, 0.1412] sex, age, birth date, deprivation index, 16 PCs
PPM010700 PSS009240|
European Ancestry|
4,085 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1396 [0.1093, 0.1696] sex, age, birth date, deprivation index, 16 PCs
PPM010701 PSS008794|
European Ancestry|
6,577 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.1414 [0.1176, 0.165] sex, age, birth date, deprivation index, 16 PCs
PPM010702 PSS008568|
Greater Middle Eastern Ancestry|
1,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.099 [0.0405, 0.1567] sex, age, birth date, deprivation index, 16 PCs
PPM010703 PSS008346|
South Asian Ancestry|
6,129 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0715 [0.0465, 0.0964] sex, age, birth date, deprivation index, 16 PCs
PPM010704 PSS008123|
East Asian Ancestry|
1,773 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0557 [0.0089, 0.1022] sex, age, birth date, deprivation index, 16 PCs
PPM010705 PSS007910|
African Ancestry|
2,358 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0669 [0.0264, 0.1071] sex, age, birth date, deprivation index, 16 PCs
PPM010706 PSS009014|
African Ancestry|
3,721 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleep duration Partial Correlation (partial-r): 0.0234 [-0.0089, 0.0555] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007910 2,358 individuals African American or Afro-Caribbean Carribean UKB
PSS009014 3,721 individuals African unspecified Nigeria (West Africa) UKB
PSS008123 1,773 individuals East Asian China (East Asia) UKB
PSS008568 1,136 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009240 4,085 individuals European Poland (NE Europe) UKB
PSS008794 6,577 individuals European Italy (South Europe) UKB
PSS008346 6,129 individuals South Asian India (South Asia) UKB
PSS009466 19,860 individuals European UK (+ Ireland) UKB