Polygenic Score (PGS) ID: PGS001992

Predicted Trait
Reported Trait Morning/evening person (chronotype)
Mapped Trait(s) chronotype measurement (EFO_0008328)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-PLR_more_evening
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 61,542
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
391,124 individuals European UK (+ Ireland) UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010811 PSS009475|
European Ancestry|
17,895 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.2051 [0.191, 0.2191] sex, age, birth date, deprivation index, 16 PCs
PPM010812 PSS009249|
European Ancestry|
3,779 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.2007 [0.1699, 0.2312] sex, age, birth date, deprivation index, 16 PCs
PPM010813 PSS008803|
European Ancestry|
5,965 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.2002 [0.1757, 0.2245] sex, age, birth date, deprivation index, 16 PCs
PPM010814 PSS008577|
Greater Middle Eastern Ancestry|
982 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.1307 [0.0681, 0.1924] sex, age, birth date, deprivation index, 16 PCs
PPM010815 PSS008355|
South Asian Ancestry|
5,368 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.1219 [0.0954, 0.1482] sex, age, birth date, deprivation index, 16 PCs
PPM010816 PSS008132|
East Asian Ancestry|
1,598 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.1252 [0.0763, 0.1735] sex, age, birth date, deprivation index, 16 PCs
PPM010817 PSS007919|
African Ancestry|
2,172 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.0871 [0.045, 0.1288] sex, age, birth date, deprivation index, 16 PCs
PPM010818 PSS009023|
African Ancestry|
3,156 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Morning/evening person (chronotype) Partial Correlation (partial-r): 0.0562 [0.0212, 0.091] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008132 1,598 individuals East Asian China (East Asia) UKB
PSS008355 5,368 individuals South Asian India (South Asia) UKB
PSS009475 17,895 individuals European UK (+ Ireland) UKB
PSS007919 2,172 individuals African American or Afro-Caribbean Carribean UKB
PSS009249 3,779 individuals European Poland (NE Europe) UKB
PSS009023 3,156 individuals African unspecified Nigeria (West Africa) UKB
PSS008577 982 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008803 5,965 individuals European Italy (South Europe) UKB