| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0000405 |
| Description | A disease or disorder that involves the digestive system. [MONDO: design_pattern] | Trait category |
Digestive system disorder
|
| Synonyms |
72 synonyms
|
| Mapped terms |
27 mapped terms
|
| Child trait(s) |
50 child traits
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS000014 (GPS_T2D) |
PGP000006 | Khera AV et al. Nat Genet (2018) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,917,436 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000014/ScoringFiles/PGS000014.txt.gz | |
| PGS000017 (GPS_IBD) |
PGP000006 | Khera AV et al. Nat Genet (2018) |
Inflammatory bowel disease | inflammatory bowel disease | 6,907,112 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000017/ScoringFiles/PGS000017.txt.gz | |
| PGS000020 (dGRS1000) |
PGP000010 | Läll K et al. Genet Med (2016) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 7,502 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000020/ScoringFiles/PGS000020.txt.gz |
| PGS000021 (GRS1) |
PGP000011 | Oram RA et al. Diabetes Care (2015) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 30 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000021/ScoringFiles/PGS000021.txt.gz | |
| PGS000022 (T1D_GRS) |
PGP000012 | Perry DJ et al. Sci Rep (2018) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 37 | - - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000022/ScoringFiles/PGS000022.txt.gz |
| PGS000023 (AA_GRS) |
PGP000013 | Onengut-Gumuscu S et al. Diabetes Care (2019) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 7 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000023/ScoringFiles/PGS000023.txt.gz |
| PGS000024 (GRS2) |
PGP000014 | Sharp SA et al. Diabetes Care (2019) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 67 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000024/ScoringFiles/PGS000024.txt.gz |
| PGS000031 (GRSt) |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 62 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000031/ScoringFiles/PGS000031.txt.gz |
| PGS000032 (GRSB) |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Type 2 diabetes (based on SNPs involved in β-cell function) | type 2 diabetes mellitus | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000032/ScoringFiles/PGS000032.txt.gz |
| PGS000033 (GRSIR) |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Type 2 diabetes (based on SNPs involved in insulin resistance) | type 2 diabetes mellitus | 10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000033/ScoringFiles/PGS000033.txt.gz |
| PGS000036 (gePS_T2D) |
PGP000023 | Mahajan A et al. Nat Genet (2018) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 171,249 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000036/ScoringFiles/PGS000036.txt.gz | |
| PGS000040 (GRS_CeD) |
PGP000028 | Abraham G et al. PLoS Genet (2014) |
Coeliac disease | celiac disease | 228 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000040/ScoringFiles/PGS000040.txt.gz |
| PGS000041 (GRS-DQ2.5-CeD) |
PGP000029 | Abraham G et al. Genome Med (2015) |
Coeliac disease | celiac disease | 2,513 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000041/ScoringFiles/PGS000041.txt.gz |
| PGS000042 (GRS-DQ2.5-CeD-imputed) |
PGP000029 | Abraham G et al. Genome Med (2015) |
Coeliac disease | celiac disease | 3,317 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000042/ScoringFiles/PGS000042.txt.gz |
| PGS000055 (PRS_CRC) |
PGP000040 | Schmit SL et al. J Natl Cancer Inst (2019) |
Colorectal cancer | colorectal cancer | 76 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000055/ScoringFiles/PGS000055.txt.gz |
| PGS000074 (CC_Colorectal) |
PGP000050 | Graff RE et al. Nat Commun (2021) |
Colorectal cancer | colorectal cancer | 103 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000074/ScoringFiles/PGS000074.txt.gz |
| PGS000081 (CC_Oral) |
PGP000050 | Graff RE et al. Nat Commun (2021) |
Oral cavity and pharyngeal cancers | oral cavity cancer, pharynx cancer |
14 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000081/ScoringFiles/PGS000081.txt.gz |
| PGS000083 (CC_Pancreas) |
PGP000050 | Graff RE et al. Nat Commun (2021) |
Pancreatic cancer | pancreatic carcinoma | 22 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000083/ScoringFiles/PGS000083.txt.gz |
| PGS000125 (Qi_T2D_2017) |
PGP000062 | Qi Q et al. Diabetes (2017) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 80 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000125/ScoringFiles/PGS000125.txt.gz |
| PGS000146 (CRC_GRS_27) |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Colorectal cancer | colorectal cancer | 27 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000146/ScoringFiles/PGS000146.txt.gz |
| PGS000147 (CRC21) |
PGP000070 | Ibáñez-Sanz G et al. Sci Rep (2017) |
Colorectal cancer | colorectal cancer | 21 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000147/ScoringFiles/PGS000147.txt.gz |
| PGS000148 (CRC63) |
PGP000071 | Jeon J et al. Gastroenterology (2018) |
Colorectal cancer | colorectal cancer | 63 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000148/ScoringFiles/PGS000148.txt.gz | |
| PGS000149 (CRC41) |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Colorectal cancer | colorectal cancer | 41 | - - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000149/ScoringFiles/PGS000149.txt.gz |
| PGS000150 (GRS48) |
PGP000073 | Weigl K et al. Gastroenterology (2018) |
Colorectal cancer | colorectal cancer | 48 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000150/ScoringFiles/PGS000150.txt.gz |
| PGS000151 (SC_GRS) |
PGP000074 | Xin J et al. Gene (2018) |
Colorectal cancer | colorectal cancer | 14 | - - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000151/ScoringFiles/PGS000151.txt.gz |
| PGS000154 (cGRS_Colorectal) |
PGP000075 | Shi Z et al. Cancer Med (2019) |
Colorectal cancer | colorectal cancer | 30 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000154/ScoringFiles/PGS000154.txt.gz |
| PGS000159 (cGRS_Pancreatic) |
PGP000075 | Shi Z et al. Cancer Med (2019) |
Pancreatic cancer | pancreatic carcinoma | 9 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000159/ScoringFiles/PGS000159.txt.gz |
| PGS000316 (GRS42_Coeliac) |
PGP000093 | Sharp SA et al. Aliment Pharmacol Ther (2020) |
Coeliac disease | celiac disease | 42 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000316/ScoringFiles/PGS000316.txt.gz | |
| PGS000330 (PRS_T2D) |
PGP000100 | Mars N et al. Nat Med (2020) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,437,380 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000330/ScoringFiles/PGS000330.txt.gz | |
| PGS000357 (PRSWEB_PHECODE145_C3-LIP-ORAL-PHARYNX_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Oral cavity cancer | oral cavity cancer | 45 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000357/ScoringFiles/PGS000357.txt.gz | |
| PGS000358 (PRSWEB_PHECODE145_UKBB-SAIGE-HRC-X145_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Oral cavity cancer | oral cavity cancer | 1,119,238 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000358/ScoringFiles/PGS000358.txt.gz | |
| PGS000359 (PRSWEB_PHECODE145.2_C3-TONGUENAS_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Tongue cancer | tongue neoplasm | 931,954 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000359/ScoringFiles/PGS000359.txt.gz | |
| PGS000363 (PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Esophageal cancer | esophageal cancer | 1,081,646 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000363/ScoringFiles/PGS000363.txt.gz | |
| PGS000364 (PRSWEB_PHECODE150_C15_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Esophageal cancer | esophageal cancer | 2,001 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000364/ScoringFiles/PGS000364.txt.gz | |
| PGS000365 (PRSWEB_PHECODE150_C3-OESOPHAGUS_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Esophageal cancer | esophageal cancer | 1,070,434 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000365/ScoringFiles/PGS000365.txt.gz | |
| PGS000366 (PRSWEB_PHECODE150_UKBB-SAIGE-HRC-X150_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Esophageal cancer | esophageal cancer | 1,119,238 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000366/ScoringFiles/PGS000366.txt.gz | |
| PGS000367 (PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 74 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000367/ScoringFiles/PGS000367.txt.gz | |
| PGS000368 (PRSWEB_PHECODE153_CRC-Huyghe_P_5e-08_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 74 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000368/ScoringFiles/PGS000368.txt.gz | |
| PGS000369 (PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 81 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000369/ScoringFiles/PGS000369.txt.gz | |
| PGS000370 (PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 87 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000370/ScoringFiles/PGS000370.txt.gz | |
| PGS000371 (PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 18 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000371/ScoringFiles/PGS000371.txt.gz | |
| PGS000372 (PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 27 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000372/ScoringFiles/PGS000372.txt.gz | |
| PGS000373 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 1,119,238 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000373/ScoringFiles/PGS000373.txt.gz | |
| PGS000374 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 41 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000374/ScoringFiles/PGS000374.txt.gz | |
| PGS000375 (PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 370 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000375/ScoringFiles/PGS000375.txt.gz | |
| PGS000376 (PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colon cancer | colon carcinoma | 1,111,490 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000376/ScoringFiles/PGS000376.txt.gz | |
| PGS000377 (PRSWEB_PHECODE153.2_C18_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colon cancer | colon carcinoma | 5,740,814 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000377/ScoringFiles/PGS000377.txt.gz | |
| PGS000378 (PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colon cancer | colon carcinoma | 1,111,399 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000378/ScoringFiles/PGS000378.txt.gz | |
| PGS000379 (PRSWEB_PHECODE153.2_C3-COLON_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colon cancer | colon carcinoma | 5,715,093 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000379/ScoringFiles/PGS000379.txt.gz | |
| PGS000380 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colon cancer | colon carcinoma | 1,119,238 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000380/ScoringFiles/PGS000380.txt.gz | |
| PGS000381 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colon cancer | colon carcinoma | 12 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000381/ScoringFiles/PGS000381.txt.gz | |
| PGS000382 (PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Colon cancer | colon carcinoma | 150 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000382/ScoringFiles/PGS000382.txt.gz | |
| PGS000383 (PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Malignant neoplasm of rectum, rectosigmoid junction, and anus | rectum cancer, rectosigmoid junction neoplasm |
1,078,799 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000383/ScoringFiles/PGS000383.txt.gz | |
| PGS000384 (PRSWEB_PHECODE153.3_C3-RECTUM_PRS-CS_MGI_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Malignant neoplasm of rectum, rectosigmoid junction, and anus | rectum cancer, rectosigmoid junction neoplasm |
1,104,018 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000384/ScoringFiles/PGS000384.txt.gz | |
| PGS000385 (PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Pancreatic cancer | pancreatic carcinoma | 17 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000385/ScoringFiles/PGS000385.txt.gz | |
| PGS000386 (PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_PT_UKB_20200608) |
PGP000118 | Fritsche LG et al. Am J Hum Genet (2020) |
Pancreatic cancer | pancreatic carcinoma | 10 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000386/ScoringFiles/PGS000386.txt.gz | |
| PGS000655 (NAFLD-10) |
PGP000119 | Namjou B et al. BMC Med (2019) |
Non-alcoholic fatty liver disease | non-alcoholic fatty liver disease | 10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000655/ScoringFiles/PGS000655.txt.gz |
| PGS000663 (wGRS22) |
PGP000123 | Kim J et al. Cancer Epidemiol Biomarkers Prev (2020) |
Pancreatic cancer | pancreatic carcinoma | 22 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000663/ScoringFiles/PGS000663.txt.gz |
| PGS000704 (HC171) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Alcoholic cirrhosis | alcoholic liver cirrhosis | 183,271 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000704/ScoringFiles/PGS000704.txt.gz |
| PGS000705 (HC188) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Gallstones | gallstones | 183,458 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000705/ScoringFiles/PGS000705.txt.gz |
| PGS000712 (T2D_HbA1c_39) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
T2D (cases vs HbA1c filtered controls) | type 2 diabetes mellitus | 183,695 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000712/ScoringFiles/PGS000712.txt.gz |
| PGS000713 (T2D) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 183,830 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000713/ScoringFiles/PGS000713.txt.gz |
| PGS000720 (PRS_Colorectal) |
PGP000135 | Jia G et al. JNCI Cancer Spectr (2020) |
Colorectal cancer | colorectal cancer | 95 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000720/ScoringFiles/PGS000720.txt.gz |
| PGS000725 (PRS_Pancreas) |
PGP000135 | Jia G et al. JNCI Cancer Spectr (2020) |
Pancreatic cancer | pancreatic carcinoma | 22 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000725/ScoringFiles/PGS000725.txt.gz |
| PGS000726 (PGS12_CIR) |
PGP000136 | Emdin CA et al. Gastroenterology (2020) |
Cirrhosis | cirrhosis of liver | 12 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000726/ScoringFiles/PGS000726.txt.gz | |
| PGS000729 (T2D_PGS) |
PGP000137 | Ritchie SC et al. Nat Metab (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 2,017,388 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000729/ScoringFiles/PGS000729.txt.gz |
| PGS000734 (PRS95_CRC) |
PGP000142 | Archambault AN et al. Gastroenterology (2019) |
Colorectal cancer | colorectal cancer | 95 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000734/ScoringFiles/PGS000734.txt.gz | |
| PGS000765 (PRS_CRC95) |
PGP000170 | Huyghe JR et al. Nat Genet (2018) |
Colorectal cancer | colorectal cancer | 95 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000765/ScoringFiles/PGS000765.txt.gz |
| PGS000776 (GRS9_Cirr) |
PGP000180 | Innes H et al. Gastroenterology (2020) |
Cirrhosis | cirrhosis of liver | 9 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000776/ScoringFiles/PGS000776.txt.gz | |
| PGS000785 (CC_Colorectal_IV) |
PGP000186 | Kachuri L et al. Nat Commun (2020) |
Colorectal cancer | colorectal cancer | 103 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000785/ScoringFiles/PGS000785.txt.gz |
| PGS000792 (CC_Oral_IV) |
PGP000186 | Kachuri L et al. Nat Commun (2020) |
Oral cavity and pharyngeal cancers | oral cavity cancer, pharynx cancer |
14 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000792/ScoringFiles/PGS000792.txt.gz |
| PGS000794 (CC_Pancreas_IV) |
PGP000186 | Kachuri L et al. Nat Commun (2020) |
Pancreatic cancer | pancreatic carcinoma | 22 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000794/ScoringFiles/PGS000794.txt.gz |
| PGS000801 (GRS40_CRC) |
PGP000190 | Hang D et al. Int J Epidemiol (2020) |
Colorectal cancer | colorectal cancer | 40 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000801/ScoringFiles/PGS000801.txt.gz |
| PGS000802 (CRC_19) |
PGP000191 | He CY et al. Genomics (2021) |
Colorectal cancer | colorectal cancer | 19 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000802/ScoringFiles/PGS000802.txt.gz | |
| PGS000804 (GRS582_T2Dmulti) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000804/ScoringFiles/PGS000804.txt.gz |
| PGS000805 (GRS582_T2Deur) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000805/ScoringFiles/PGS000805.txt.gz |
| PGS000806 (GRS582_T2Dafr) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000806/ScoringFiles/PGS000806.txt.gz |
| PGS000807 (GRS582_T2Dasn) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000807/ScoringFiles/PGS000807.txt.gz |
| PGS000808 (GRS582_T2Dhis) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000808/ScoringFiles/PGS000808.txt.gz |
| PGS000832 (T2D-GRS) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 384 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000832/ScoringFiles/PGS000832.txt.gz |
| PGS000833 (T1D) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 66 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000833/ScoringFiles/PGS000833.txt.gz |
| PGS000848 (T2D_Adiposity) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with adiposity) | type 2 diabetes mellitus | 6 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz |
| PGS000849 (T2D_Impaired_Lipids) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with impaired lipids) | type 2 diabetes mellitus | 3 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000849/ScoringFiles/PGS000849.txt.gz |
| PGS000850 (T2D_Insulin_Action) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with insulin action) | type 2 diabetes mellitus | 16 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz |
| PGS000851 (T2D_Insulin_Action_Secretion) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with insulin action/secretion) | type 2 diabetes mellitus | 37 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz |
| PGS000852 (T2D_Insulin_Secretion_1) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with insulin secretion) | type 2 diabetes mellitus | 8 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz |
| PGS000853 (T2D_Insulin_Secretion_2) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with insulin secretion) | type 2 diabetes mellitus | 21 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz |
| PGS000854 (T2D_BetaCell) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with beta cell function) | type 2 diabetes mellitus | 27 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz |
| PGS000855 (T2D_Lipodystrophy) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with lipodystrophy) | type 2 diabetes mellitus | 18 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz |
| PGS000856 (T2D_LiverLipids) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with liver lipids) | type 2 diabetes mellitus | 3 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000856/ScoringFiles/PGS000856.txt.gz |
| PGS000857 (T2D_Obesity) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with obesity) | type 2 diabetes mellitus | 4 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000857/ScoringFiles/PGS000857.txt.gz |
| PGS000858 (T2D_Proinsulin) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with proinsulin levels) | type 2 diabetes mellitus | 6 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz |
| PGS000864 (T2D-gPRS) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 389,243 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000864/ScoringFiles/PGS000864.txt.gz |
| PGS000868 (T2D_221) |
PGP000214 | Aksit MA et al. J Clin Endocrinol Metab (2020) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 221 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000868/ScoringFiles/PGS000868.txt.gz |
| PGS000869 (T1D_48) |
PGP000214 | Aksit MA et al. J Clin Endocrinol Metab (2020) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 48 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000869/ScoringFiles/PGS000869.txt.gz |
| PGS000872 (PRS-5) |
PGP000215 | Bianco C et al. J Hepatol (2020) |
Non-alcoholic fatty liver disease | non-alcoholic fatty liver disease | 5 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000872/ScoringFiles/PGS000872.txt.gz | |
| PGS000996 (GBE_HC262) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Diverticular disease/diverticulitis | diverticular disease, diverticulitis |
368 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000996/ScoringFiles/PGS000996.txt.gz |
| PGS000997 (GBE_HC1106) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Diverticular disease of intestine (time-to-event) | diverticular disease | 5,757 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000997/ScoringFiles/PGS000997.txt.gz |
| PGS001014 (GBE_HC654) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Other disorders of pancreatic internal secretion (time-to-event) | pancreas disease | 69 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001014/ScoringFiles/PGS001014.txt.gz |
| PGS001174 (GBE_HC1125) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Cholelithiasis (time-to-event) | cholelithiasis | 970 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001174/ScoringFiles/PGS001174.txt.gz |
| PGS001256 (GBE_HC188) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Gallstones | gallstones | 876 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001256/ScoringFiles/PGS001256.txt.gz |
| PGS001288 (GBE_HC95) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Inflammatory bowel disease | inflammatory bowel disease | 195 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001288/ScoringFiles/PGS001288.txt.gz |
| PGS001293 (GBE_HC1123) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Other diseases of liver (time-to-event) | liver disease | 92 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001293/ScoringFiles/PGS001293.txt.gz |
| PGS001294 (GBE_HC649) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Non-insulin-dependent diabetes (time-to-event) | type 2 diabetes mellitus | 3,496 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001294/ScoringFiles/PGS001294.txt.gz |
| PGS001295 (GBE_HC165) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 385 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001295/ScoringFiles/PGS001295.txt.gz |
| PGS001296 (GBE_HC648) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Insulin-dependent diabetes mellitus (time-to-event) | type 1 diabetes mellitus | 356 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001296/ScoringFiles/PGS001296.txt.gz |
| PGS001297 (GBE_HC337) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 69 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001297/ScoringFiles/PGS001297.txt.gz |
| PGS001300 (GBE_BIN21068) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Celiac disease or gluten sensitivity, diagnosed | celiac disease | 9 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001300/ScoringFiles/PGS001300.txt.gz |
| PGS001301 (GBE_HC303) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Malabsorption/coeliac disease | celiac disease | 428 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001301/ScoringFiles/PGS001301.txt.gz |
| PGS001306 (GBE_HC201) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ulcerative colitis | ulcerative colitis | 179 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001306/ScoringFiles/PGS001306.txt.gz |
| PGS001307 (GBE_HC1102) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ulcerative colitis (time-to-event) | ulcerative colitis | 809 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001307/ScoringFiles/PGS001307.txt.gz |
| PGS001308 (GBE_HC321) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Sjogren's syndrome/sicca syndrome | Sjogren syndrome | 7 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001308/ScoringFiles/PGS001308.txt.gz |
| PGS001327 (GBE_HC221) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Diabetes | diabetes mellitus | 4,053 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001327/ScoringFiles/PGS001327.txt.gz |
| PGS001329 (GBE_HC652) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Unspecified diabetes mellitus (time-to-event) | diabetes mellitus | 2,270 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001329/ScoringFiles/PGS001329.txt.gz |
| PGS001330 (GBE_HC1101) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Crohn's disease [regional enteritis] (time-to-event) | Crohn's disease | 220 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001330/ScoringFiles/PGS001330.txt.gz |
| PGS001331 (GBE_HC322) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Crohn's disease | Crohn's disease | 257 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001331/ScoringFiles/PGS001331.txt.gz |
| PGS001357 (T2D_AnnoPred_PRS) |
PGP000252 | Ye Y et al. Circ Genom Precis Med (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 2,996,761 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001357/ScoringFiles/PGS001357.txt.gz | |
| PGS001369 (GBE_HC1090) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Acute appendicitis (time-to-event) | appendicitis | 4 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001369/ScoringFiles/PGS001369.txt.gz |
| PGS001371 (GBE_INI2976) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Age diabetes diagnosed | diabetes mellitus, age at diagnosis |
26 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001371/ScoringFiles/PGS001371.txt.gz |
| PGS001390 (GBE_HC1084) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Duodenal ulcer (time-to-event) | duodenal ulcer | 220 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001390/ScoringFiles/PGS001390.txt.gz |
| PGS001516 (GBE_HC1112) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Other diseases of intestine (time-to-event) | intestinal disease | 90 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001516/ScoringFiles/PGS001516.txt.gz |
| PGS001776 (PRS45_CC) |
PGP000256 | Gafni A et al. PLoS One (2021) |
Colorectal cancer | colorectal cancer | 45 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001776/ScoringFiles/PGS001776.txt.gz |
| PGS001777 (3-SNP_cirr) |
PGP000258 | Whitfield JB et al. J Hepatol (2021) |
Cirrhosis (alcohol related) | alcoholic liver cirrhosis | 3 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001777/ScoringFiles/PGS001777.txt.gz |
| PGS001781 (T2D_PRSCS) |
PGP000261 | Tamlander M et al. Commun Biol (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,091,673 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001781/ScoringFiles/PGS001781.txt.gz |
| PGS001785 (1kgeur_gbmi_leaveUKBBout_AcApp_pst_eff_a1_b0.5_phiauto) |
PGP000262 | Wang Y et al. Cell Genom (2023) |
Acute appendicitis | appendicitis | 911,334 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001785/ScoringFiles/PGS001785.txt.gz |
| PGS001802 (portability-PLR_153) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Colorectal cancer | colorectal cancer | 2,821 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001802/ScoringFiles/PGS001802.txt.gz |
| PGS001811 (portability-PLR_208) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Benign neoplasm of colon | benign colon neoplasm | 2,231 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001811/ScoringFiles/PGS001811.txt.gz |
| PGS001812 (portability-PLR_211) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Benign neoplasm of other parts of digestive system | benign digestive system neoplasm | 801 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001812/ScoringFiles/PGS001812.txt.gz |
| PGS001817 (portability-PLR_250.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 825 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001817/ScoringFiles/PGS001817.txt.gz |
| PGS001818 (portability-PLR_250.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 30,745 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001818/ScoringFiles/PGS001818.txt.gz |
| PGS001851 (portability-PLR_530.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Esophagitis, GERD and related diseases | gastroesophageal reflux disease, esophagitis |
13,855 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001851/ScoringFiles/PGS001851.txt.gz |
| PGS001852 (portability-PLR_535.6) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Duodenitis | duodenitis | 191 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001852/ScoringFiles/PGS001852.txt.gz |
| PGS001853 (portability-PLR_540) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Appendiceal conditions | disorder of appendix | 19 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001853/ScoringFiles/PGS001853.txt.gz |
| PGS001855 (portability-PLR_555.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ulcerative colitis | ulcerative colitis | 1,505 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001855/ScoringFiles/PGS001855.txt.gz |
| PGS001856 (portability-PLR_557.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Celiac disease | celiac disease | 1,661 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001856/ScoringFiles/PGS001856.txt.gz |
| PGS001858 (portability-PLR_564) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Functional digestive disorders | digestive system disease | 764 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001858/ScoringFiles/PGS001858.txt.gz |
| PGS001859 (portability-PLR_565.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Anal and rectal polyp | polyp of rectum, anal polyp |
789 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001859/ScoringFiles/PGS001859.txt.gz |
| PGS001860 (portability-PLR_571.5) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Other chronic nonalcoholic liver disease | liver disease | 497 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001860/ScoringFiles/PGS001860.txt.gz |
| PGS001861 (portability-PLR_574) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Cholelithiasis and cholecystitis | cholelithiasis, Cholecystitis |
2,059 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001861/ScoringFiles/PGS001861.txt.gz |
| PGS001862 (portability-PLR_575) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Other biliary tract disease | biliary tract disease | 151 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001862/ScoringFiles/PGS001862.txt.gz |
| PGS001894 (portability-PLR_celiac_gluten) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Diagnosed with coeliac disease or gluten sensitivity | celiac disease | 484 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001894/ScoringFiles/PGS001894.txt.gz |
| PGS002013 (portability-ldpred2_153) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Colorectal cancer | colorectal cancer | 648,559 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002013/ScoringFiles/PGS002013.txt.gz |
| PGS002019 (portability-ldpred2_208) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Benign neoplasm of colon | benign colon neoplasm | 667,546 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002019/ScoringFiles/PGS002019.txt.gz |
| PGS002020 (portability-ldpred2_211) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Benign neoplasm of other parts of digestive system | benign digestive system neoplasm | 503,832 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002020/ScoringFiles/PGS002020.txt.gz |
| PGS002025 (portability-ldpred2_250.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 106,800 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002025/ScoringFiles/PGS002025.txt.gz |
| PGS002026 (portability-ldpred2_250.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 830,783 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002026/ScoringFiles/PGS002026.txt.gz |
| PGS002063 (portability-ldpred2_530.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Esophagitis, GERD and related diseases | gastroesophageal reflux disease, esophagitis |
836,413 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002063/ScoringFiles/PGS002063.txt.gz |
| PGS002064 (portability-ldpred2_540) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Appendiceal conditions | disorder of appendix | 497,422 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002064/ScoringFiles/PGS002064.txt.gz |
| PGS002066 (portability-ldpred2_555.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ulcerative colitis | ulcerative colitis | 566,637 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002066/ScoringFiles/PGS002066.txt.gz |
| PGS002067 (portability-ldpred2_557.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Celiac disease | celiac disease | 58,231 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002067/ScoringFiles/PGS002067.txt.gz |
| PGS002069 (portability-ldpred2_564) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Functional digestive disorders | digestive system disease | 747,820 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002069/ScoringFiles/PGS002069.txt.gz |
| PGS002070 (portability-ldpred2_565.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Anal and rectal polyp | polyp of rectum, anal polyp |
584,133 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002070/ScoringFiles/PGS002070.txt.gz |
| PGS002071 (portability-ldpred2_571.5) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Other chronic nonalcoholic liver disease | liver disease | 352,506 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002071/ScoringFiles/PGS002071.txt.gz |
| PGS002072 (portability-ldpred2_574) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Cholelithiasis and cholecystitis | cholelithiasis, Cholecystitis |
428,587 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002072/ScoringFiles/PGS002072.txt.gz |
| PGS002073 (portability-ldpred2_575) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Other biliary tract disease | biliary tract disease | 363,801 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002073/ScoringFiles/PGS002073.txt.gz |
| PGS002107 (portability-ldpred2_celiac_gluten) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Diagnosed with coeliac disease or gluten sensitivity | celiac disease | 39,066 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002107/ScoringFiles/PGS002107.txt.gz |
| PGS002243 (ldpred_t2d) |
PGP000271 | Mars N et al. Cell Genom (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,431,973 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz | |
| PGS002252 (PRS_CRC) |
PGP000279 | Archambault AN et al. J Natl Cancer Inst (2022) |
Colorectal cancer | colorectal cancer | 141 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002252/ScoringFiles/PGS002252.txt.gz |
| PGS002256 (GRS4_GDM) |
PGP000282 | Wu Q et al. Diabetol Metab Syndr (2022) |
Gestational diabetes mellitus in early pregnancy | gestational diabetes | 4 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002256/ScoringFiles/PGS002256.txt.gz | |
| PGS002264 (PRS_Combined) |
PGP000293 | Sharma S et al. Gastroenterology (2022) |
Pancreatic ductal adenocarcinoma | pancreatic ductal adenocarcinoma | 49 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002264/ScoringFiles/PGS002264.txt.gz |
| PGS002265 (PRS140_CRC) |
PGP000294 | Thomas M et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 140 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002265/ScoringFiles/PGS002265.txt.gz |
| PGS002277 (pPS_Insulin_secretion_1) |
PGP000305 | Siddiqui MK et al. Diabetologia (2022) |
Type 2 diabetes (based on SNPs associated with insulin secretion) | type 2 diabetes mellitus | 8 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz |
| PGS002282 (GRS68_NAFLD) |
PGP000312 | Schnurr TM et al. Hepatol Commun (2022) |
Nonalcoholic fatty liver disease | non-alcoholic fatty liver disease | 68 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002282/ScoringFiles/PGS002282.txt.gz |
| PGS002283 (GRS15_NAFLD) |
PGP000312 | Schnurr TM et al. Hepatol Commun (2022) |
Nonalcoholic fatty liver disease | non-alcoholic fatty liver disease | 15 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002283/ScoringFiles/PGS002283.txt.gz |
| PGS002298 (PRS14_esophageal) |
PGP000328 | Choi J et al. Int J Cancer (2020) |
Esophageal cancer | esophageal carcinoma | 14 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002298/ScoringFiles/PGS002298.txt.gz |
| PGS002299 (PRS3_gastric) |
PGP000328 | Choi J et al. Int J Cancer (2020) |
Gastric cancer | gastric cancer | 3 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002299/ScoringFiles/PGS002299.txt.gz |
| PGS002308 (PRScsx_T2D) |
PGP000331 | Ge T et al. Genome Med (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,259,754 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002308/ScoringFiles/PGS002308.txt.gz |
| PGS002321 (disease_DIABETES_ANY_DIAGNOSED.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002321/ScoringFiles/PGS002321.txt.gz |
| PGS002324 (disease_ENDOCRINE_DIABETES.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002324/ScoringFiles/PGS002324.txt.gz |
| PGS002354 (disease_T2D.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002354/ScoringFiles/PGS002354.txt.gz |
| PGS002379 (disease_T2D.BOLT-LMM-BBJ) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 920,930 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002379/ScoringFiles/PGS002379.txt.gz |
| PGS002393 (disease_DIABETES_ANY_DIAGNOSED.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 3,813 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002393/ScoringFiles/PGS002393.txt.gz |
| PGS002396 (disease_ENDOCRINE_DIABETES.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
3,681 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002396/ScoringFiles/PGS002396.txt.gz |
| PGS002426 (disease_T2D.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 3,947 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002426/ScoringFiles/PGS002426.txt.gz |
| PGS002442 (disease_DIABETES_ANY_DIAGNOSED.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 15,915 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002442/ScoringFiles/PGS002442.txt.gz |
| PGS002445 (disease_ENDOCRINE_DIABETES.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
15,629 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002445/ScoringFiles/PGS002445.txt.gz |
| PGS002475 (disease_T2D.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 16,275 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002475/ScoringFiles/PGS002475.txt.gz |
| PGS002491 (disease_DIABETES_ANY_DIAGNOSED.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 95,066 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002491/ScoringFiles/PGS002491.txt.gz |
| PGS002494 (disease_ENDOCRINE_DIABETES.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
93,293 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002494/ScoringFiles/PGS002494.txt.gz |
| PGS002524 (disease_T2D.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 95,287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002524/ScoringFiles/PGS002524.txt.gz |
| PGS002540 (disease_DIABETES_ANY_DIAGNOSED.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 598 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002540/ScoringFiles/PGS002540.txt.gz |
| PGS002543 (disease_ENDOCRINE_DIABETES.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
528 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002543/ScoringFiles/PGS002543.txt.gz |
| PGS002573 (disease_T2D.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 673 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002573/ScoringFiles/PGS002573.txt.gz |
| PGS002589 (disease_DIABETES_ANY_DIAGNOSED.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 267 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002589/ScoringFiles/PGS002589.txt.gz |
| PGS002592 (disease_ENDOCRINE_DIABETES.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
187 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002592/ScoringFiles/PGS002592.txt.gz |
| PGS002622 (disease_T2D.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 293 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002622/ScoringFiles/PGS002622.txt.gz |
| PGS002638 (disease_DIABETES_ANY_DIAGNOSED.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 247,386 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002638/ScoringFiles/PGS002638.txt.gz |
| PGS002641 (disease_ENDOCRINE_DIABETES.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
256,678 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002641/ScoringFiles/PGS002641.txt.gz |
| PGS002671 (disease_T2D.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 258,382 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002671/ScoringFiles/PGS002671.txt.gz |
| PGS002687 (disease_DIABETES_ANY_DIAGNOSED.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Diabetes (any type) | diabetes mellitus | 923,080 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002687/ScoringFiles/PGS002687.txt.gz |
| PGS002690 (disease_ENDOCRINE_DIABETES.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Endocrine and diabetes diseases | diabetes mellitus, endocrine system disease |
905,637 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002690/ScoringFiles/PGS002690.txt.gz |
| PGS002720 (disease_T2D.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 911,809 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002720/ScoringFiles/PGS002720.txt.gz |
| PGS002733 (GRS17_T2D) |
PGP000342 | Pezzilli S et al. Diabetes Metab (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 17 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002733/ScoringFiles/PGS002733.txt.gz |
| PGS002740 (PRS22_PC) |
PGP000347 | Yuan C et al. Ann Oncol (2022) |
Pancreatic cancer | pancreatic carcinoma | 22 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002740/ScoringFiles/PGS002740.txt.gz |
| PGS002742 (PRS115_EAS) |
PGP000354 | Ping J et al. Int J Cancer (2022) |
Colorectal cancer | colorectal cancer | 115 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002742/ScoringFiles/PGS002742.txt.gz | |
| PGS002743 (PRS115_EUR) |
PGP000354 | Ping J et al. Int J Cancer (2022) |
Colorectal cancer | colorectal cancer | 115 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002743/ScoringFiles/PGS002743.txt.gz | |
| PGS002744 (PRS115_EUR_EAS) |
PGP000354 | Ping J et al. Int J Cancer (2022) |
Colorectal cancer | colorectal cancer | 115 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002744/ScoringFiles/PGS002744.txt.gz | |
| PGS002747 (PRS_GI) |
PGP000359 | Liu Y et al. Cancer Med (2022) |
Gastrointestinal cancer | Digestive System Carcinoma | 106 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002747/ScoringFiles/PGS002747.txt.gz |
| PGS002758 (Colorectal_cancer_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Colorectal cancer | colorectal cancer | 1,087,843 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002758/ScoringFiles/PGS002758.txt.gz |
| PGS002771 (Type_2_diabetes_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,091,608 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002771/ScoringFiles/PGS002771.txt.gz |
| PGS002779 (GTG_T2D_maxCT) |
PGP000365 | Wong CK et al. PLoS One (2022) |
Incident type 2 diabetes | type 2 diabetes mellitus | 46,353 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002779/ScoringFiles/PGS002779.txt.gz | |
| PGS002780 (GTG_T2D_SCT) |
PGP000365 | Wong CK et al. PLoS One (2022) |
Incident type 2 diabetes | type 2 diabetes mellitus | 419,209 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002780/ScoringFiles/PGS002780.txt.gz | |
| PGS003089 (ExPRSweb_T2D_2443_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 488,969 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003089/ScoringFiles/PGS003089.txt.gz | |
| PGS003090 (ExPRSweb_T2D_2443_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,888 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003090/ScoringFiles/PGS003090.txt.gz | |
| PGS003091 (ExPRSweb_T2D_2443_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 2,707 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003091/ScoringFiles/PGS003091.txt.gz | |
| PGS003092 (ExPRSweb_T2D_2443_DBSLMM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 10,304,000 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003092/ScoringFiles/PGS003092.txt.gz | |
| PGS003093 (ExPRSweb_T2D_2443_PRSCS_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,113,832 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003093/ScoringFiles/PGS003093.txt.gz | |
| PGS003094 (ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 266,890 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003094/ScoringFiles/PGS003094.txt.gz | |
| PGS003095 (ExPRSweb_T2D_29358691-GCST005413_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 45 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003095/ScoringFiles/PGS003095.txt.gz | |
| PGS003096 (ExPRSweb_T2D_29358691-GCST005413_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 46 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003096/ScoringFiles/PGS003096.txt.gz | |
| PGS003097 (ExPRSweb_T2D_29358691-GCST005413_DBSLMM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 229 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003097/ScoringFiles/PGS003097.txt.gz | |
| PGS003098 (ExPRSweb_T2D_29358691-GCST005413_PRSCS_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,116,101 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003098/ScoringFiles/PGS003098.txt.gz | |
| PGS003099 (ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 555,512 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003099/ScoringFiles/PGS003099.txt.gz | |
| PGS003100 (ExPRSweb_T2D_30054458-GCST006867_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,693 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003100/ScoringFiles/PGS003100.txt.gz | |
| PGS003101 (ExPRSweb_T2D_30054458-GCST006867_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,693 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003101/ScoringFiles/PGS003101.txt.gz | |
| PGS003102 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,052,574 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003102/ScoringFiles/PGS003102.txt.gz | |
| PGS003103 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 945,820 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003103/ScoringFiles/PGS003103.txt.gz | |
| PGS003104 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 374,510 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003104/ScoringFiles/PGS003104.txt.gz | |
| PGS003105 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 187 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003105/ScoringFiles/PGS003105.txt.gz | |
| PGS003106 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 187 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003106/ScoringFiles/PGS003106.txt.gz | |
| PGS003107 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_DBSLMM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 995 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003107/ScoringFiles/PGS003107.txt.gz | |
| PGS003108 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,118,480 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003108/ScoringFiles/PGS003108.txt.gz | |
| PGS003109 (ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 311,565 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003109/ScoringFiles/PGS003109.txt.gz | |
| PGS003110 (ExPRSweb_T2D_29358691-GCST005413_PT_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 118 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003110/ScoringFiles/PGS003110.txt.gz | |
| PGS003111 (ExPRSweb_T2D_29358691-GCST005413_PLINK_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 143 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003111/ScoringFiles/PGS003111.txt.gz | |
| PGS003112 (ExPRSweb_T2D_29358691-GCST005413_DBSLMM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 222 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003112/ScoringFiles/PGS003112.txt.gz | |
| PGS003113 (ExPRSweb_T2D_29358691-GCST005413_PRSCS_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,117,087 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003113/ScoringFiles/PGS003113.txt.gz | |
| PGS003114 (ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 555,528 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003114/ScoringFiles/PGS003114.txt.gz | |
| PGS003115 (ExPRSweb_T2D_30054458-GCST006867_PT_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 31,462 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003115/ScoringFiles/PGS003115.txt.gz | |
| PGS003116 (ExPRSweb_T2D_30054458-GCST006867_PLINK_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 31,462 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003116/ScoringFiles/PGS003116.txt.gz | |
| PGS003117 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,052,993 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003117/ScoringFiles/PGS003117.txt.gz | |
| PGS003118 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 945,921 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003118/ScoringFiles/PGS003118.txt.gz | |
| PGS003119 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 407,553 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003119/ScoringFiles/PGS003119.txt.gz | |
| PGS003120 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 193 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003120/ScoringFiles/PGS003120.txt.gz | |
| PGS003121 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 193 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003121/ScoringFiles/PGS003121.txt.gz | |
| PGS003122 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_DBSLMM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 264 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003122/ScoringFiles/PGS003122.txt.gz | |
| PGS003123 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,119,522 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003123/ScoringFiles/PGS003123.txt.gz | |
| PGS003353 (GRS_T2D) |
PGP000405 | Kim YJ et al. Nat Commun (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003353/ScoringFiles/PGS003353.txt.gz |
| PGS003386 (best_COADREAD) |
PGP000413 | Namba S et al. Cancer Res (2022) |
Colorectal cancer | colorectal carcinoma | 61 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003386/ScoringFiles/PGS003386.txt.gz |
| PGS003387 (best_ESCA_BEEA) |
PGP000413 | Namba S et al. Cancer Res (2022) |
Esophageal adenocarcinoma or Barrett’s esophagus | Barrett's esophagus, esophageal adenocarcinoma |
601,980 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003387/ScoringFiles/PGS003387.txt.gz |
| PGS003388 (best_ESCA_EA) |
PGP000413 | Namba S et al. Cancer Res (2022) |
Esophageal adenocarcinoma | esophageal adenocarcinoma | 356,743 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003388/ScoringFiles/PGS003388.txt.gz |
| PGS003395 (PRScsx_CRC) |
PGP000414 | Xin J et al. Genome Med (2023) |
Colorectal cancer | colorectal cancer | 1,145,689 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003395/ScoringFiles/PGS003395.txt.gz |
| PGS003402 (PRS_T2D) |
PGP000419 | Lamri A et al. Elife (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,838 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003402/ScoringFiles/PGS003402.txt.gz | |
| PGS003431 (LDPred2-inf) |
PGP000438 | Briggs SEW et al. BMJ (2022) |
Colorectal cancer | colorectal cancer | 1,104,409 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003431/ScoringFiles/PGS003431.txt.gz | |
| PGS003432 (LDPred2-grid) |
PGP000438 | Briggs SEW et al. BMJ (2022) |
Colorectal cancer | colorectal cancer | 1,104,409 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003432/ScoringFiles/PGS003432.txt.gz | |
| PGS003433 (LDPred2-grid-sp) |
PGP000438 | Briggs SEW et al. BMJ (2022) |
Colorectal cancer | colorectal cancer | 616,956 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003433/ScoringFiles/PGS003433.txt.gz | |
| PGS003434 (SCT) |
PGP000438 | Briggs SEW et al. BMJ (2022) |
Colorectal cancer | colorectal cancer | 194,756 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003434/ScoringFiles/PGS003434.txt.gz | |
| PGS003435 (CT) |
PGP000438 | Briggs SEW et al. BMJ (2022) |
Colorectal cancer | colorectal cancer | 13,446 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003435/ScoringFiles/PGS003435.txt.gz | |
| PGS003436 (GWAS-sig) |
PGP000438 | Briggs SEW et al. BMJ (2022) |
Colorectal cancer | colorectal cancer | 50 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003436/ScoringFiles/PGS003436.txt.gz | |
| PGS003439 (PRSCC_140) |
PGP000441 | Su YR et al. Cancer Epidemiol Biomarkers Prev (2023) |
Colorectal cancer | colorectal cancer | 140 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003439/ScoringFiles/PGS003439.txt.gz | |
| PGS003443 (PRScsx_T2D_LAT_EURweights) |
PGP000445 | Huerta-Chagoya A et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,092,496 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003443/ScoringFiles/PGS003443.txt.gz | |
| PGS003444 (PRScsx_T2D_LAT_EASweights) |
PGP000445 | Huerta-Chagoya A et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,001,579 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003444/ScoringFiles/PGS003444.txt.gz | |
| PGS003445 (PRScsx_T2D_LAT_LATweights) |
PGP000445 | Huerta-Chagoya A et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,149,210 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003445/ScoringFiles/PGS003445.txt.gz | |
| PGS003451 (PRS2_MZL) |
PGP000448 | Berndt SI et al. Leukemia (2022) |
Marginal zone lymphoma | marginal zone B-cell lymphoma | 2 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003451/ScoringFiles/PGS003451.txt.gz |
| PGS003728 (PS_T2D_183-AGEN) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 183 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003728/ScoringFiles/PGS003728.txt.gz |
| PGS003729 (PS_T2D_293-DIAGRAM) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 293 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003729/ScoringFiles/PGS003729.txt.gz |
| PGS003730 (PS_T2D_287-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003730/ScoringFiles/PGS003730.txt.gz |
| PGS003731 (PS_T2D_282-SAS-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 282 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003731/ScoringFiles/PGS003731.txt.gz |
| PGS003732 (PS_T2D_287-HIS-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003732/ScoringFiles/PGS003732.txt.gz |
| PGS003733 (PS_T2D_287-EUR-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003733/ScoringFiles/PGS003733.txt.gz |
| PGS003734 (PS_T2D_280-EAS-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 280 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003734/ScoringFiles/PGS003734.txt.gz |
| PGS003735 (PS_T2D_276-AFR-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 276 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003735/ScoringFiles/PGS003735.txt.gz |
| PGS003739 (PRS81_CoC) |
PGP000470 | Xin J et al. EBioMedicine (2023) |
Colorectal cancer | colorectal carcinoma | 81 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003739/ScoringFiles/PGS003739.txt.gz | |
| PGS003742 (PRS19_PC) |
PGP000470 | Xin J et al. EBioMedicine (2023) |
Pancreatic cancer | pancreatic neoplasm | 19 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003742/ScoringFiles/PGS003742.txt.gz | |
| PGS003749 (ModelT1D_under25) |
PGP000472 | Shoaib M et al. Genet Epidemiol (2023) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 6,612 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003749/ScoringFiles/PGS003749.txt.gz | |
| PGS003750 (ModelT1D) |
PGP000472 | Shoaib M et al. Genet Epidemiol (2023) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 7,835 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003750/ScoringFiles/PGS003750.txt.gz | |
| PGS003751 (ModelT2D_over45) |
PGP000472 | Shoaib M et al. Genet Epidemiol (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 354 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003751/ScoringFiles/PGS003751.txt.gz | |
| PGS003752 (ModelT2D) |
PGP000472 | Shoaib M et al. Genet Epidemiol (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 333 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003752/ScoringFiles/PGS003752.txt.gz | |
| PGS003760 (PRS49_EOCRC) |
PGP000480 | Wang H et al. Genome Med (2023) |
Early onset colorectal cancer | colorectal cancer | 49 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003760/ScoringFiles/PGS003760.txt.gz |
| PGS003850 (CRC_PRS_200loci) |
PGP000491 | Fernandez-Rozadilla C et al. Nat Genet (2022) |
Colorectal cancer | colorectal cancer | 205 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003850/ScoringFiles/PGS003850.txt.gz |
| PGS003851 (CRC_PRS_EUR) |
PGP000294 | Thomas M et al. Am J Hum Genet (2020) |
Colorectal cancer | colorectal cancer | 1,180,765 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003851/ScoringFiles/PGS003851.txt.gz |
| PGS003852 (CRC_PRS_EUR_EAS) |
PGP000492 | Thomas M T et al. medRxiv (2023) |Pre |
Colorectal cancer | colorectal cancer | 1,016,596 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003852/ScoringFiles/PGS003852.txt.gz |
| PGS003867 (T2D_PRScs_ARB) |
PGP000501 | Shim I et al. Nature Communications (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,068,166 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003867/ScoringFiles/PGS003867.txt.gz |
| PGS003979 (CRC_PRSCS) |
PGP000515 | Tamlander M et al. Br J Cancer (2023) |
Colorectal cancer | colorectal carcinoma | 1,088,133 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003979/ScoringFiles/PGS003979.txt.gz |
| PGS003981 (dbslmm.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,103,311 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003981/ScoringFiles/PGS003981.txt.gz | |
| PGS003982 (dbslmm.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,071,764 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003982/ScoringFiles/PGS003982.txt.gz | |
| PGS003993 (dbslmm.auto.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 63,182 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003993/ScoringFiles/PGS003993.txt.gz | |
| PGS003997 (lassosum.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 8,406 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003997/ScoringFiles/PGS003997.txt.gz | |
| PGS003998 (lassosum.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,548 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003998/ScoringFiles/PGS003998.txt.gz | |
| PGS004009 (lassosum.auto.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 4,031 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004009/ScoringFiles/PGS004009.txt.gz | |
| PGS004013 (lassosum.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 22,690 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004013/ScoringFiles/PGS004013.txt.gz | |
| PGS004014 (lassosum.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 95,649 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004014/ScoringFiles/PGS004014.txt.gz | |
| PGS004020 (lassosum.CV.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 6,682 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004020/ScoringFiles/PGS004020.txt.gz | |
| PGS004023 (ldpred2.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,018,068 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004023/ScoringFiles/PGS004023.txt.gz | |
| PGS004024 (ldpred2.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 958,046 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004024/ScoringFiles/PGS004024.txt.gz | |
| PGS004035 (ldpred2.auto.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 56,562 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004035/ScoringFiles/PGS004035.txt.gz | |
| PGS004038 (ldpred2.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,018,068 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004038/ScoringFiles/PGS004038.txt.gz | |
| PGS004039 (ldpred2.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 958,046 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004039/ScoringFiles/PGS004039.txt.gz | |
| PGS004051 (megaprs.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 784,928 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004051/ScoringFiles/PGS004051.txt.gz | |
| PGS004052 (megaprs.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 800,598 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004052/ScoringFiles/PGS004052.txt.gz | |
| PGS004063 (megaprs.auto.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 56,288 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004063/ScoringFiles/PGS004063.txt.gz | |
| PGS004067 (megaprs.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 784,928 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004067/ScoringFiles/PGS004067.txt.gz | |
| PGS004068 (megaprs.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 800,598 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004068/ScoringFiles/PGS004068.txt.gz | |
| PGS004078 (megaprs.CV.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 56,288 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004078/ScoringFiles/PGS004078.txt.gz | |
| PGS004081 (prscs.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,073,268 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004081/ScoringFiles/PGS004081.txt.gz | |
| PGS004082 (prscs.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,043,329 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004082/ScoringFiles/PGS004082.txt.gz | |
| PGS004093 (prscs.auto.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 61,651 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004093/ScoringFiles/PGS004093.txt.gz | |
| PGS004097 (prscs.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,073,268 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004097/ScoringFiles/PGS004097.txt.gz | |
| PGS004102 (prscs.CV.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 61,651 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004102/ScoringFiles/PGS004102.txt.gz | |
| PGS004105 (pt_clump.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 139 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004105/ScoringFiles/PGS004105.txt.gz | |
| PGS004106 (pt_clump.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 35 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004106/ScoringFiles/PGS004106.txt.gz | |
| PGS004117 (pt_clump.auto.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 131 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004117/ScoringFiles/PGS004117.txt.gz | |
| PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 774 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004121/ScoringFiles/PGS004121.txt.gz | |
| PGS004122 (pt_clump_nested.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 297 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004122/ScoringFiles/PGS004122.txt.gz | |
| PGS004132 (pt_clump_nested.CV.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 354 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004132/ScoringFiles/PGS004132.txt.gz | |
| PGS004135 (sbayesr.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 912,746 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004135/ScoringFiles/PGS004135.txt.gz | |
| PGS004136 (sbayesr.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 930,497 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004136/ScoringFiles/PGS004136.txt.gz | |
| PGS004147 (sbayesr.auto.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 45,996 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004147/ScoringFiles/PGS004147.txt.gz | |
| PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,102,205 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004151/ScoringFiles/PGS004151.txt.gz | |
| PGS004152 (UKBB_EnsPGS.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,071,786 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004152/ScoringFiles/PGS004152.txt.gz | |
| PGS004162 (UKBB_EnsPGS.GCST90013445.T1D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 62,645 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004162/ScoringFiles/PGS004162.txt.gz | |
| PGS004171 (t1d_1) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 1 diabetes | type 1 diabetes mellitus | 520 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004171/ScoringFiles/PGS004171.txt.gz |
| PGS004172 (t1d_2) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 1 diabetes | type 1 diabetes mellitus | 70 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004172/ScoringFiles/PGS004172.txt.gz |
| PGS004173 (t1d_3) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 1 diabetes | type 1 diabetes mellitus | 295 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004173/ScoringFiles/PGS004173.txt.gz |
| PGS004174 (t1d_4) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 1 diabetes | type 1 diabetes mellitus | 49 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004174/ScoringFiles/PGS004174.txt.gz |
| PGS004175 (t1d_5) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 1 diabetes | type 1 diabetes mellitus | 315 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004175/ScoringFiles/PGS004175.txt.gz |
| PGS004181 (t2d_1) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 10,202 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004181/ScoringFiles/PGS004181.txt.gz |
| PGS004182 (t2d_2) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 10,778 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004182/ScoringFiles/PGS004182.txt.gz |
| PGS004183 (t2d_3) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 8,154 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004183/ScoringFiles/PGS004183.txt.gz |
| PGS004184 (t2d_4) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 9,645 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004184/ScoringFiles/PGS004184.txt.gz |
| PGS004185 (t2d_5) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 3,277 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004185/ScoringFiles/PGS004185.txt.gz |
| PGS004223 (PRS139_T2D) |
PGP000523 | Lin J et al. Sci Total Environ (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 139 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004223/ScoringFiles/PGS004223.txt.gz |
| PGS004225 (PRS46_T2DEastAsia) |
PGP000526 | Liu J et al. Nutrients (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 46 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004225/ScoringFiles/PGS004225.txt.gz |
| PGS004226 (PRS50_T2DEur) |
PGP000526 | Liu J et al. Nutrients (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 50 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004226/ScoringFiles/PGS004226.txt.gz |
| PGS004240 (PRS89_CRC) |
PGP000541 | Fan L et al. Int J Cancer (2023) |
Colorectal cancer | colorectal carcinoma | 89 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004240/ScoringFiles/PGS004240.txt.gz |
| PGS004243 (PRS67_colorectum) |
PGP000542 | Kim ES et al. NPJ Precis Oncol (2023) |
Colorectal cancer | colorectal carcinoma | 67 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004243/ScoringFiles/PGS004243.txt.gz |
| PGS004250 (PRS19_pancreas) |
PGP000542 | Kim ES et al. NPJ Precis Oncol (2023) |
Pancreatic cancer | pancreatic carcinoma | 19 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004250/ScoringFiles/PGS004250.txt.gz |
| PGS004253 (uc_ldpred2) |
PGP000545 | Middha P et al. Nat Commun (2024) |
Ulcerative colitis | ulcerative colitis | 744,575 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004253/ScoringFiles/PGS004253.txt.gz | |
| PGS004254 (cd_ldpred2) |
PGP000545 | Middha P et al. Nat Commun (2024) |
Crohn's disease | Crohn's disease | 744,682 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004254/ScoringFiles/PGS004254.txt.gz | |
| PGS004270 (GenoBoost_inflammatory_bowel_disease_0) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004270/ScoringFiles/PGS004270.txt.gz |
| PGS004271 (GenoBoost_inflammatory_bowel_disease_1) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004271/ScoringFiles/PGS004271.txt.gz |
| PGS004272 (GenoBoost_inflammatory_bowel_disease_2) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004272/ScoringFiles/PGS004272.txt.gz |
| PGS004273 (GenoBoost_inflammatory_bowel_disease_3) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 110 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004273/ScoringFiles/PGS004273.txt.gz |
| PGS004274 (GenoBoost_inflammatory_bowel_disease_4) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 40 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004274/ScoringFiles/PGS004274.txt.gz |
| PGS004300 (GenoBoost_colorectal_cancer_0) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 70 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004300/ScoringFiles/PGS004300.txt.gz |
| PGS004301 (GenoBoost_colorectal_cancer_1) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 600 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004301/ScoringFiles/PGS004301.txt.gz |
| PGS004302 (GenoBoost_colorectal_cancer_2) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 300 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004302/ScoringFiles/PGS004302.txt.gz |
| PGS004303 (GenoBoost_colorectal_cancer_3) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 200 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004303/ScoringFiles/PGS004303.txt.gz |
| PGS004304 (GenoBoost_colorectal_cancer_4) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 700 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004304/ScoringFiles/PGS004304.txt.gz |
| PGS004310 (GenoBoost_type_2_diabetes_0) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 7,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004310/ScoringFiles/PGS004310.txt.gz |
| PGS004311 (GenoBoost_type_2_diabetes_1) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 4,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004311/ScoringFiles/PGS004311.txt.gz |
| PGS004312 (GenoBoost_type_2_diabetes_2) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 7,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004312/ScoringFiles/PGS004312.txt.gz |
| PGS004313 (GenoBoost_type_2_diabetes_3) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 8,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004313/ScoringFiles/PGS004313.txt.gz |
| PGS004314 (GenoBoost_type_2_diabetes_4) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004314/ScoringFiles/PGS004314.txt.gz |
| PGS004320 (PRS16_UGI) |
PGP000551 | Liu W et al. Nutrients (2023) |
Upper gastrointestinal cancer | Digestive System Carcinoma | 16 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004320/ScoringFiles/PGS004320.txt.gz |
| PGS004323 (PRS91_T2D) |
PGP000557 | Tan Q et al. J Hazard Mater (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 91 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004323/ScoringFiles/PGS004323.txt.gz |
| PGS004445 (disease.D12.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
D12 (Benign neoplasm of colon, rectum, anus and anal canal) | colorectal carcinoma | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004445/ScoringFiles/PGS004445.txt.gz |
| PGS004468 (disease.K21.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K21 (Gastroesophageal reflux disease) | gastroesophageal reflux disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004468/ScoringFiles/PGS004468.txt.gz |
| PGS004469 (disease.K22.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K22 (Other diseases of oesophagus) | esophageal disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004469/ScoringFiles/PGS004469.txt.gz |
| PGS004470 (disease.K29.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K29 (Gastritis and duodenitis) | gastritis | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004470/ScoringFiles/PGS004470.txt.gz |
| PGS004474 (disease.K57.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K57 (Diverticular disease of intestine) | diverticular disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004474/ScoringFiles/PGS004474.txt.gz |
| PGS004475 (disease.K59.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K59 (Other functional intestinal disorders) | intestinal disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004475/ScoringFiles/PGS004475.txt.gz |
| PGS004476 (disease.K80.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K80 (Cholelithiasis) | cholelithiasis | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004476/ScoringFiles/PGS004476.txt.gz |
| PGS004499 (disease.T2D.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004499/ScoringFiles/PGS004499.txt.gz |
| PGS004515 (meta.D12.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
D12 (Benign neoplasm of colon, rectum, anus and anal canal) | colorectal carcinoma | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004515/ScoringFiles/PGS004515.txt.gz |
| PGS004538 (meta.K21.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K21 (Gastroesophageal reflux disease) | gastroesophageal reflux disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004538/ScoringFiles/PGS004538.txt.gz |
| PGS004539 (meta.K22.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K22 (Other diseases of oesophagus) | esophageal disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004539/ScoringFiles/PGS004539.txt.gz |
| PGS004540 (meta.K29.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K29 (Gastritis and duodenitis) | gastritis | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004540/ScoringFiles/PGS004540.txt.gz |
| PGS004544 (meta.K57.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K57 (Diverticular disease of intestine) | diverticular disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004544/ScoringFiles/PGS004544.txt.gz |
| PGS004545 (meta.K59.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K59 (Other functional intestinal disorders) | intestinal disease | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004545/ScoringFiles/PGS004545.txt.gz |
| PGS004546 (meta.K80.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
K80 (Cholelithiasis) | cholelithiasis | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004546/ScoringFiles/PGS004546.txt.gz |
| PGS004569 (meta.T2D.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004569/ScoringFiles/PGS004569.txt.gz |
| PGS004580 (CRC_PRSCS) |
PGP000562 | Youssef O et al. Lab Invest (2024) |
Colorectal cancer | colorectal carcinoma | 1,099,906 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004580/ScoringFiles/PGS004580.txt.gz |
| PGS004586 (PPS_CRC) |
PGP000564 | Xin J et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004586/ScoringFiles/PGS004586.txt.gz |
| PGS004602 (PRS424_T2D) |
PGP000580 | Zhuang P et al. Diabetes Care (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 424 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004602/ScoringFiles/PGS004602.txt.gz |
| PGS004614 (DivD_SNPWeights) |
PGP000592 | Wu Y et al. Cell Genom (2023) |
Diverticular disease | diverticular disease | 1,082,282 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004614/ScoringFiles/PGS004614.txt.gz |
| PGS004615 (PGS_weights_TMM_All_of_1group) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 855,161 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004615/ScoringFiles/PGS004615.txt.gz |
| PGS004616 (PGS_weights_TMM_HighBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 855,161 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004616/ScoringFiles/PGS004616.txt.gz |
| PGS004617 (PGS_weights_TMM_LowBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 855,161 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004617/ScoringFiles/PGS004617.txt.gz |
| PGS004618 (PGS_weights_BBJ2nd_All_of_1group) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 728,824 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004618/ScoringFiles/PGS004618.txt.gz |
| PGS004619 (PGS_weights_BBJ2nd_HighBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 728,824 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004619/ScoringFiles/PGS004619.txt.gz |
| PGS004620 (PGS_weights_BBJ2nd_LowBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 728,824 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004620/ScoringFiles/PGS004620.txt.gz |
| PGS004621 (cirrhosis_pgs_eur) |
PGP000594 | Ghouse J et al. Nat Genet (2024) |
Cirrhosis | cirrhosis of liver | 1,089,806 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004621/ScoringFiles/PGS004621.txt.gz |
| PGS004689 (colorectal_cancer) |
PGP000596 | Hu J et al. JNCI Cancer Spectr (2024) |
Colorectal cancer | colorectal carcinoma | 1,077,789 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004689/ScoringFiles/PGS004689.txt.gz | |
| PGS004693 (pancreatic_cancer) |
PGP000596 | Hu J et al. JNCI Cancer Spectr (2024) |
Pancreatic cancer | pancreatic carcinoma | 6,351,686 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004693/ScoringFiles/PGS004693.txt.gz | |
| PGS004837 (t2d_PRSmix_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 3,306,136 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004837/ScoringFiles/PGS004837.txt.gz |
| PGS004838 (t2d_PRSmix_sas) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,586,458 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004838/ScoringFiles/PGS004838.txt.gz |
| PGS004839 (t2d_PRSmixPlus_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 4,594,694 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004839/ScoringFiles/PGS004839.txt.gz |
| PGS004840 (t2d_PRSmixPlus_sas) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,586,458 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004840/ScoringFiles/PGS004840.txt.gz |
| PGS004859 (T2D_PRS_CS) |
PGP000605 | Deutsch AJ et al. Diabetes Care (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,108,235 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004859/ScoringFiles/PGS004859.txt.gz |
| PGS004868 (T2DPGS) |
PGP000617 | Yun JS et al. Cardiovasc Diabetol (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,580,804 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004868/ScoringFiles/PGS004868.txt.gz |
| PGS004870 (INTERVENE_MegaPRS_T2D) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 930,506 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004870/ScoringFiles/PGS004870.txt.gz | |
| PGS004874 (INTERVENE_MegaPRS_T1D) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 56,916 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004874/ScoringFiles/PGS004874.txt.gz | |
| PGS004876 (INTERVENE_MegaPRS_Appendicitis) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Appendicitis | appendicitis | 601,835 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004876/ScoringFiles/PGS004876.txt.gz |
| PGS004880 (INTERVENE_MegaPRS_Colorectal_cancer) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 843,248 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004880/ScoringFiles/PGS004880.txt.gz | |
| PGS004887 (T2D_gePGS) |
PGP000619 | Mandla R et al. Genome Med (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,117,628 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004887/ScoringFiles/PGS004887.txt.gz | |
| PGS004904 (PRS127_CRC) |
PGP000636 | Jiang F et al. Int J Cancer (2023) |
Colorectal cancer | colorectal carcinoma | 127 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004904/ScoringFiles/PGS004904.txt.gz |
| PGS004912 (PRS183) |
PGP000643 | Tian J et al. Genome Med (2024) |
Colorectal neoplasm | colorectal carcinoma | 183 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004912/ScoringFiles/PGS004912.txt.gz | |
| PGS004913 (PRSALC) |
PGP000645 | Schwantes-An TH et al. Hepatol Commun (2024) |
Alcohol-associated liver cirrhosis | alcoholic liver cirrhosis | 20 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004913/ScoringFiles/PGS004913.txt.gz | |
| PGS004923 (T2D_metaGRS) |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,349,896 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004923/ScoringFiles/PGS004923.txt.gz | |
| PGS004945 (PRS87_CRC) |
PGP000671 | Gao P et al. Int J Cancer (2023) |
Colorectal cancer | colorectal cancer | 87 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004945/ScoringFiles/PGS004945.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM000023 | PGS000014 (GPS_T2D) |
PSS000017| European Ancestry| 288,978 individuals |
PGP000006 | Khera AV et al. Nat Genet (2018) |
Reported Trait: Type 2 diabetes | — | AUROC: 0.73 [0.72, 0.73] | Nagelkerke’s R2 (estimate of variance explained by the PGS after covariate adjustment): 0.029 | age; sex; Ancestry PC 1-4; genotyping chip | — |
| PPM002477 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes | — | C-index: 0.709 [0.696, 0.722] | Hazard ratio (HR, top 10% vs. remaining 90%): 2.0 [1.73, 2.31] | Sex, age, principal components, assessment center | — |
| PPM002478 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in males | — | C-index: 0.68 [0.663, 0.697] | — | Age, principal components and assessment center | — |
| PPM002479 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in females | — | C-index: 0.705 [0.682, 0.728] | — | Age, principal components and assessment center | — |
| PPM002480 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes | — | C-index: 0.776 [0.764, 0.788] | — | Sex, age, principal components, assessment center, polyexposure score | — |
| PPM002481 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes | — | C-index: 0.844 [0.834, 0.854] | — | Sex, age, principal components, assessment center, clinical risk score | — |
| PPM002482 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes | — | C-index: 0.855 [0.845, 0.865] | — | Sex, age, principal components, assessment center, polyexposure socre, clinical risk score | — |
| PPM002483 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in females | — | C-index: 0.786 [0.765, 0.807] | — | Age, principal components, assessment center, polyexposure score | — |
| PPM002485 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in females | — | C-index: 0.859 [0.842, 0.876] | — | Sex, age, principal components, assessment center, clinical risk score | — |
| PPM002486 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in males | — | C-index: 0.749 [0.734, 0.764] | — | Age, principal components, assessment center, polyexposure score | — |
| PPM002487 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in males | — | C-index: 0.821 [0.808, 0.834] | — | Age, principal components, assessment center, polyexposure socre, clinical risk score | — |
| PPM002488 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in males | — | C-index: 0.834 [0.821, 0.847] | — | Sex, age, principal components, assessment center, clinical risk score | — |
| PPM002484 | PGS000014 (GPS_T2D) |
PSS001117| European Ancestry| 68,229 individuals |
PGP000218 | He Y et al. Diabetes Care (2021) |Ext. |
Reported Trait: Incident type II diabetes in females | — | C-index: 0.869 [0.853, 0.885] | — | Age, principal components, assessment center, polyexposure socre, clinical risk score | — |
| PPM015522 | PGS000014 (GPS_T2D) |
PSS009971| Multi-ancestry (including European)| 36,422 individuals |
PGP000381 | Hao L et al. Nat Med (2022) |Ext. |
Reported Trait: Type 2 diabetes mellitus | OR: 1.75 [1.57, 1.95] | — | — | 4 genetic PCs | — |
| PPM019100 | PGS000014 (GPS_T2D) |
PSS011181| Ancestry Not Reported| 3,071 individuals |
PGP000504 | Duschek E et al. Sci Rep (2023) |Ext. |
Reported Trait: Incident type 2 diabetes | — | AUROC: 0.613 [0.565, 0.657] | — | — | — |
| PPM019098 | PGS000014 (GPS_T2D) |
PSS011181| Ancestry Not Reported| 3,071 individuals |
PGP000504 | Duschek E et al. Sci Rep (2023) |Ext. |
Reported Trait: Incident type 2 diabetes | OR: 1.67 [1.37, 2.03] | — | — | Age, Sex, BMI, Physical activity, FamRS | — |
| PPM019099 | PGS000014 (GPS_T2D) |
PSS011181| Ancestry Not Reported| 3,071 individuals |
PGP000504 | Duschek E et al. Sci Rep (2023) |Ext. |
Reported Trait: Prevelant type 2 diabetes | — | AUROC: 0.869 [0.842, 0.896] | — | — | — |
| PPM019097 | PGS000014 (GPS_T2D) |
PSS011181| Ancestry Not Reported| 3,071 individuals |
PGP000504 | Duschek E et al. Sci Rep (2023) |Ext. |
Reported Trait: Prevelant type 2 diabetes | OR: 6.21 [5.06, 7.74] | — | — | Age, Sex, BMI, Physical activity, FamRS | — |
| PPM021428 | PGS000014 (GPS_T2D) |
PSS011737| European Ancestry| 109,021 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.51 [1.48, 1.55] | AUROC: 0.7 [0.695, 0.705] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021437 | PGS000014 (GPS_T2D) |
PSS011747| European Ancestry| 245,177 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.71 [1.67, 1.74] | AUROC: 0.731 [0.726, 0.736] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021458 | PGS000014 (GPS_T2D) |
PSS011738| European Ancestry| 38,941 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.58 [1.47, 1.7] | C-index: 0.737 [0.719, 0.754] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021465 | PGS000014 (GPS_T2D) |
PSS011746| European Ancestry| 232,808 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.45 [1.42, 1.49] | C-index: 0.686 [0.679, 0.692] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021484 | PGS000014 (GPS_T2D) |
PSS011735| African Ancestry| 44,346 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.21 [1.17, 1.24] | AUROC: 0.717 [0.71, 0.723] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021506 | PGS000014 (GPS_T2D) |
PSS011736| Hispanic or Latin American Ancestry| 33,652 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.39 [1.34, 1.44] | AUROC: 0.757 [0.75, 0.764] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021531 | PGS000014 (GPS_T2D) |
PSS011740| East Asian Ancestry| 1,149 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | OR: 0.99 [0.85, 1.16] | AUROC: 0.585 [0.541, 0.629] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021553 | PGS000014 (GPS_T2D) |
PSS011741| South Asian Ancestry| 852 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | OR: 1.03 [0.87, 1.21] | AUROC: 0.639 [0.596, 0.683] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021571 | PGS000014 (GPS_T2D) |
PSS011739| Additional Asian Ancestries| 870 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | OR: 0.82 [0.69, 0.97] | AUROC: 0.662 [0.618, 0.706] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021589 | PGS000014 (GPS_T2D) |
PSS011743| African Ancestry| 6,871 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.27 [1.18, 1.38] | AUROC: 0.714 [0.695, 0.733] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021615 | PGS000014 (GPS_T2D) |
PSS011745| East Asian Ancestry| 1,432 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.28 [1.01, 1.61] | AUROC: 0.705 [0.648, 0.763] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021635 | PGS000014 (GPS_T2D) |
PSS011749| South Asian Ancestry| 6,992 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.48 [1.39, 1.58] | AUROC: 0.711 [0.696, 0.726] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021653 | PGS000014 (GPS_T2D) |
PSS011742| African Ancestry| 6,019 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.12 [1.01, 1.23] | C-index: 0.641 [0.614, 0.669] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021677 | PGS000014 (GPS_T2D) |
PSS011744| East Asian Ancestry| 1,350 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.24 [0.9, 1.7] | C-index: 0.684 [0.609, 0.758] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021699 | PGS000014 (GPS_T2D) |
PSS011748| South Asian Ancestry| 5,685 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.14 [1.05, 1.24] | C-index: 0.605 [0.582, 0.628] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM000026 | PGS000017 (GPS_IBD) |
PSS000016| European Ancestry| 288,978 individuals |
PGP000006 | Khera AV et al. Nat Genet (2018) |
Reported Trait: Inflammatory bowel disease | — | AUROC: 0.63 [0.62, 0.64] | Nagelkerke’s R2 (estimate of variance explained by the PGS after covariate adjustment): 0.021 | age; sex; Ancestry PC 1-4; genotyping chip | — |
| PPM012874 | PGS000017 (GPS_IBD) |
PSS009588| European Ancestry| 1,433 individuals |
PGP000288 | Garcia-Etxebarria K et al. Sci Rep (2022) |Ext. |
Reported Trait: Inflammatory Bowel Disease | — | AUROC: 0.69 [0.66, 0.72] | — | — | — |
| PPM000040 | PGS000020 (dGRS1000) |
PSS000025| European Ancestry| 6,280 individuals |
PGP000010 | Läll K et al. Genet Med (2016) |
Reported Trait: Incident type 2 diabetes | HR: 1.48 [1.32, 1.66] | C-index: 0.79 [0.771, 0.812] | — | BMI category, smoking level, waist-to-hip ratio, waist circumference, physical activity level, history of high blood glucose, fruit and vegetable consumption, and sex. | Cox age-as-time-scale |
| PPM000132 | PGS000021 (GRS1) |
PSS000083| European Ancestry| 2,768 individuals |
PGP000038 | Patel KA et al. Diabetes (2016) |Ext. |
Reported Trait: Type 1 diabetes aetiology (non-monogenic) | — | AUROC: 0.87 [0.86, 0.89] | — | — | Testing the ability of the GRS to discriminate between two sets of cases: - Positive: individuals with type 1 diabetes - Negative: individuals with diabetes and a maturity-onset diabetes of young (MODY) mutation |
| PPM000041 | PGS000021 (GRS1) |
PSS000026| European Ancestry| 223 individuals |
PGP000011 | Oram RA et al. Diabetes Care (2015) |
Reported Trait: Severe insulin deficiency | — | AUROC: 0.96 [0.94, 0.99] | AUROC (without covariates): 0.87 | islet auto-antibody status, body mass index (BMI), age at diagnosis | — |
| PPM000046 | PGS000021 (GRS1) |
PSS000030| African Ancestry| 3,949 individuals |
PGP000013 | Onengut-Gumuscu S et al. Diabetes Care (2019) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.798 | — | — | — |
| PPM000049 | PGS000021 (GRS1) |
PSS000032| European Ancestry| 374,000 individuals |
PGP000014 | Sharp SA et al. Diabetes Care (2019) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.893 | — | — | — |
| PPM000042 | PGS000022 (T1D_GRS) |
PSS000029| European Ancestry| 1,447 individuals |
PGP000012 | Perry DJ et al. Sci Rep (2018) |
Reported Trait: Type 1 diabetes | — | AUROC: 0.8508 | — | — | AUROCs are reported with respect to unrelated-control samples |
| PPM000043 | PGS000022 (T1D_GRS) |
PSS000028| Hispanic or Latin American Ancestry| 252 individuals |
PGP000012 | Perry DJ et al. Sci Rep (2018) |
Reported Trait: Type 1 diabetes | — | AUROC: 0.9003 | — | — | AUROCs are reported with respect to unrelated-control samples |
| PPM000044 | PGS000022 (T1D_GRS) |
PSS000027| African Ancestry| 299 individuals |
PGP000012 | Perry DJ et al. Sci Rep (2018) |
Reported Trait: Type 1 diabetes | — | AUROC: 0.7522 | — | — | AUROCs are reported with respect to unrelated-control samples |
| PPM000045 | PGS000023 (AA_GRS) |
PSS000030| African Ancestry| 3,949 individuals |
PGP000013 | Onengut-Gumuscu S et al. Diabetes Care (2019) |
Reported Trait: Type 1 diabetes | — | AUROC: 0.87 | — | — | NOTE: Evaluated using cross-validation on training samples (20% heldout, 1000 iterations) |
| PPM000047 | PGS000023 (AA_GRS) |
PSS000031| African Ancestry| 145 individuals |
PGP000013 | Onengut-Gumuscu S et al. Diabetes Care (2019) |
Reported Trait: Type 1 diabetes | — | AUROC: 0.779 | — | — | — |
| PPM018536 | PGS000023 (AA_GRS) |
PSS011012| Multi-ancestry (including European)| 39,820 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.781 | — | — | — |
| PPM018537 | PGS000023 (AA_GRS) |
PSS011009| Multi-ancestry (including European)| 57,643 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.817 | — | — | — |
| PPM018539 | PGS000023 (AA_GRS) |
PSS011011| European Ancestry| 16,663 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | — | PPV (+PRS): 97.0 % PPV (reference): 86.0 % |
eMERGE type 1 diabetes algorithm | — |
| PPM018541 | PGS000023 (AA_GRS) |
PSS011010| Multi-ancestry (excluding European)| 40,980 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | — | PPV (+PRS): 86.0 % PPV (reference): 71.0 % |
eMERGE type 1 diabetes algorithm | — |
| PPM018543 | PGS000023 (AA_GRS) |
PSS011013| Multi-ancestry (excluding European)| 4,881 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | — | PPV (+PRS): 83.0 % PPV (reference): 53.0 % |
eMERGE type 1 diabetes algorithm | — |
| PPM000048 | PGS000024 (GRS2) |
PSS000032| European Ancestry| 374,000 individuals |
PGP000014 | Sharp SA et al. Diabetes Care (2019) |
Reported Trait: Type 1 diabetes | — | AUROC: 0.921 | Youden index: 0.698 | — | — |
| PPM000753 | PGS000024 (GRS2) |
PSS000368| Ancestry Not Reported| 7,798 individuals |
PGP000091 | Ferrat LA et al. Nat Med (2020) |Ext. |
Reported Trait: Type 1 diabetes (5 years horizon time; landmark age 2 years) | — | AUROC: 0.93 | — | autoantibodies, family history | — |
| PPM000754 | PGS000024 (GRS2) |
PSS000368| Ancestry Not Reported| 7,798 individuals |
PGP000091 | Ferrat LA et al. Nat Med (2020) |Ext. |
Reported Trait: Type 1 diabetes (8 years horizon time; landmark age 2 years) | — | AUROC: 0.87 | — | autoantibodies, family history | — |
| PPM000755 | PGS000024 (GRS2) |
PSS000368| Ancestry Not Reported| 7,798 individuals |
PGP000091 | Ferrat LA et al. Nat Med (2020) |Ext. |
Reported Trait: Type 1 diabetes (5 years horizon time; landmark age 4 years) | — | AUROC: 0.96 | — | autoantibodies, family history | — |
| PPM000751 | PGS000024 (GRS2) |
PSS000368| Ancestry Not Reported| 7,798 individuals |
PGP000091 | Ferrat LA et al. Nat Med (2020) |Ext. |
Reported Trait: Type 1 diabetes (1 year horizon time; landmark age 2 years) | — | AUROC: 0.96 | — | autoantibodies, family history | — |
| PPM000752 | PGS000024 (GRS2) |
PSS000368| Ancestry Not Reported| 7,798 individuals |
PGP000091 | Ferrat LA et al. Nat Med (2020) |Ext. |
Reported Trait: Type 1 diabetes (3 years horizon time; landmark age 2 years) | — | AUROC: 0.94 | — | autoantibodies, family history | — |
| PPM000750 | PGS000024 (GRS2) |
PSS000368| Ancestry Not Reported| 7,798 individuals |
PGP000091 | Ferrat LA et al. Nat Med (2020) |Ext. |
Reported Trait: Type 1 diabetes (by age 8; landmark age 2 years) | — | AUROC: 0.73 [0.7, 0.77] | — | — | — |
| PPM002249 | PGS000024 (GRS2) |
PSS001087| European Ancestry| 3,930 individuals |
PGP000211 | Aly DM et al. Nat Genet (2021) |Ext. |
Reported Trait: Severe Insulin-Deficient Diabetes | OR: 1.0 [0.93, 1.07] | — | — | PC1-10 | 8 proxy variants were used to evaluate this score |
| PPM002250 | PGS000024 (GRS2) |
PSS001088| European Ancestry| 3,869 individuals |
PGP000211 | Aly DM et al. Nat Genet (2021) |Ext. |
Reported Trait: Severe Insulin-Resistant Diabetes | OR: 1.0 [0.93, 1.07] | — | — | PC1-10 | 8 proxy variants were used to evaluate this score |
| PPM002251 | PGS000024 (GRS2) |
PSS001085| European Ancestry| 4,116 individuals |
PGP000211 | Aly DM et al. Nat Genet (2021) |Ext. |
Reported Trait: Moderate Obesity-related Diabetes | OR: 1.01 [0.95, 1.08] | — | — | PC1-10 | 8 proxy variants were used to evaluate this score |
| PPM002252 | PGS000024 (GRS2) |
PSS001084| European Ancestry| 5,597 individuals |
PGP000211 | Aly DM et al. Nat Genet (2021) |Ext. |
Reported Trait: Moderate Age-Related Diabetes | OR: 0.99 [0.94, 1.04] | — | — | PC1-10 | 8 proxy variants were used to evaluate this score |
| PPM002248 | PGS000024 (GRS2) |
PSS001086| European Ancestry| 3,194 individuals |
PGP000211 | Aly DM et al. Nat Genet (2021) |Ext. |
Reported Trait: Severe Autoimmune Diabetes | OR: 2.55 [2.28, 2.86] | — | — | PC1-10 | 8 proxy variants were used to evaluate this score |
| PPM014801 | PGS000024 (GRS2) |
PSS009895| European Ancestry| 1,168 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.864 [0.823, 0.905] | — | — | — |
| PPM014803 | PGS000024 (GRS2) |
PSS009893| African Ancestry| 366 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.851 [0.805, 0.897] | — | — | — |
| PPM014805 | PGS000024 (GRS2) |
PSS009894| Hispanic or Latin American Ancestry| 412 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.935 [0.906, 0.964] | — | — | — |
| PPM014807 | PGS000024 (GRS2) |
PSS009896| Ancestry Not Reported| 99 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.79 [0.679, 0.902] | — | — | — |
| PPM018532 | PGS000024 (GRS2) |
PSS011012| Multi-ancestry (including European)| 39,820 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.875 | — | — | — |
| PPM018533 | PGS000024 (GRS2) |
PSS011009| Multi-ancestry (including European)| 57,643 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.822 | — | — | — |
| PPM018534 | PGS000024 (GRS2) |
PSS011014| European Ancestry| 34,939 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.888 | — | — | — |
| PPM018535 | PGS000024 (GRS2) |
PSS011014| European Ancestry| 34,939 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | AUROC: 0.858 | — | — | — |
| PPM018538 | PGS000024 (GRS2) |
PSS011011| European Ancestry| 16,663 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | — | PPV (+PRS): 100.0 % PPV (reference): 86.0 % |
eMERGE type 1 diabetes algorithm | — |
| PPM018540 | PGS000024 (GRS2) |
PSS011010| Multi-ancestry (excluding European)| 40,980 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | — | PPV (+PRS): 93.0 % PPV (reference): 71.0 % |
eMERGE type 1 diabetes algorithm | — |
| PPM018542 | PGS000024 (GRS2) |
PSS011014| European Ancestry| 34,939 individuals |
PGP000477 | Deutsch AJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes | — | — | PPV (+PRS): 97.0 % PPV (reference): 71.0 % |
eMERGE type 1 diabetes algorithm | — |
| PPM020098 | PGS000024 (GRS2) |
PSS011295| Ancestry Not Reported| 1,798 individuals |
PGP000519 | Thomas NJ et al. Diabetes Care (2023) |Ext. |
Reported Trait: Type 1 diabetes vs autoantibody negative T2D | — | — | p-value (inferior to): 0.0001 | — | — |
| PPM021124 | PGS000024 (GRS2) |
PSS011531| European Ancestry| 9,465 individuals |
PGP000614 | Qu HQ et al. Diabetes Obes Metab (2021) |Ext. |
Reported Trait: Type 1 diabetes | β: -0.22 | AUROC: 0.87 | — | — | — |
| PPM021125 | PGS000024 (GRS2) |
PSS011532| European Ancestry| 9,450 individuals |
PGP000614 | Qu HQ et al. Diabetes Obes Metab (2021) |Ext. |
Reported Trait: Type 1 diabetes | β: -0.234 | AUROC: 0.862 | — | — | — |
| PPM000062 | PGS000031 (GRSt) |
PSS000044| European Ancestry| 3,471 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.06 [1.04, 1.08] | C-index: 0.906 [0.892, 0.92] | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model" |
| PPM000063 | PGS000031 (GRSt) |
PSS000043| European Ancestry| 1,650 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.06 [1.02, 1.1] | C-index: 0.853 [0.81, 0.896] | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model" |
| PPM000064 | PGS000031 (GRSt) |
PSS000042| African Ancestry| 820 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.05 [1.0, 1.09] | C-index: 0.771 [0.727, 0.814] | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model", SNPs were not weighted by their effect size as the betas were measure in Europeans |
| PPM000065 | PGS000032 (GRSB) |
PSS000044| European Ancestry| 3,471 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.1 [1.06, 1.14] | — | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model" |
| PPM000066 | PGS000032 (GRSB) |
PSS000043| European Ancestry| 1,650 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.09 [1.02, 1.17] | — | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model" |
| PPM000067 | PGS000032 (GRSB) |
PSS000042| African Ancestry| 820 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.06 [0.99, 1.15] | — | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model", SNPs were not weighted by their effect size as the betas were measure in Europeans |
| PPM002415 | PGS000032 (GRSB) |
PSS001092| Ancestry Not Reported| 5,740 individuals |
PGP000214 | Aksit MA et al. J Clin Endocrinol Metab (2020) |Ext. |
Reported Trait: Cystic-fibrosis related diabetes onset | HR: 1.192 | — | — | PCs(1-4), site of recruitment | — |
| PPM000068 | PGS000033 (GRSIR) |
PSS000044| European Ancestry| 3,471 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 0.98 [0.93, 1.04] | — | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model" |
| PPM000069 | PGS000033 (GRSIR) |
PSS000043| European Ancestry| 1,650 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.01 [0.91, 1.12] | — | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model" |
| PPM000070 | PGS000033 (GRSIR) |
PSS000042| African Ancestry| 820 individuals |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Reported Trait: Incident type 2 diabetes cases | HR: 1.06 [0.99, 1.15] | — | — | age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels | Results from the "Clinical model", SNPs were not weighted by their effect size as the betas were measure in Europeans |
| PPM000080 | PGS000036 (gePS_T2D) |
PSS000054| European Ancestry| 324,870 individuals |
PGP000024 | Udler MS et al. Endocr Rev (2019) |Ext. |
Reported Trait: Type 2 diabetes | — | AUROC: 0.66 | — | genotyping array, first 6 PCs of ancestry | — |
| PPM000081 | PGS000036 (gePS_T2D) |
PSS000054| European Ancestry| 324,870 individuals |
PGP000024 | Udler MS et al. Endocr Rev (2019) |Ext. |
Reported Trait: Type 2 diabetes | — | AUROC: 0.73 | — | age, sex, genotyping array, first 6 PCs of ancestry | — |
| PPM014802 | PGS000036 (gePS_T2D) |
PSS009895| European Ancestry| 1,168 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.661 [0.606, 0.716] | — | — | — |
| PPM014804 | PGS000036 (gePS_T2D) |
PSS009893| African Ancestry| 366 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.574 [0.506, 0.643] | — | — | — |
| PPM014806 | PGS000036 (gePS_T2D) |
PSS009894| Hispanic or Latin American Ancestry| 412 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.722 [0.667, 0.778] | — | — | — |
| PPM014808 | PGS000036 (gePS_T2D) |
PSS009896| Ancestry Not Reported| 99 individuals |
PGP000338 | Oram RA et al. Diabetes Care (2022) |Ext. |
Reported Trait: Diabetes autoantibody positive insulin sensitive | — | AUROC: 0.677 [0.532, 0.822] | — | — | — |
| PPM021427 | PGS000036 (gePS_T2D) |
PSS011737| European Ancestry| 109,021 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.53 [1.5, 1.56] | AUROC: 0.701 [0.696, 0.706] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021436 | PGS000036 (gePS_T2D) |
PSS011747| European Ancestry| 245,177 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.73 [1.69, 1.76] | AUROC: 0.733 [0.728, 0.737] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021454 | PGS000036 (gePS_T2D) |
PSS011738| European Ancestry| 38,941 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.63 [1.52, 1.75] | C-index: 0.742 [0.725, 0.759] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021464 | PGS000036 (gePS_T2D) |
PSS011746| European Ancestry| 232,808 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.46 [1.42, 1.5] | C-index: 0.687 [0.68, 0.693] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021482 | PGS000036 (gePS_T2D) |
PSS011735| African Ancestry| 44,346 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.21 [1.18, 1.25] | AUROC: 0.717 [0.711, 0.724] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021505 | PGS000036 (gePS_T2D) |
PSS011736| Hispanic or Latin American Ancestry| 33,652 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.41 [1.36, 1.46] | AUROC: 0.759 [0.752, 0.766] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021521 | PGS000036 (gePS_T2D) |
PSS011740| East Asian Ancestry| 1,149 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | OR: 1.25 [1.07, 1.46] | AUROC: 0.608 [0.566, 0.651] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021547 | PGS000036 (gePS_T2D) |
PSS011741| South Asian Ancestry| 852 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | OR: 1.23 [1.04, 1.45] | AUROC: 0.651 [0.609, 0.693] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021572 | PGS000036 (gePS_T2D) |
PSS011739| Additional Asian Ancestries| 870 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | OR: 1.2 [1.01, 1.42] | AUROC: 0.657 [0.612, 0.701] | — | Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021591 | PGS000036 (gePS_T2D) |
PSS011743| African Ancestry| 6,871 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.25 [1.16, 1.35] | AUROC: 0.71 [0.691, 0.729] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021612 | PGS000036 (gePS_T2D) |
PSS011745| East Asian Ancestry| 1,432 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.39 [1.1, 1.77] | AUROC: 0.722 [0.668, 0.776] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021637 | PGS000036 (gePS_T2D) |
PSS011749| South Asian Ancestry| 6,992 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Type 2 diabetes | OR: 1.44 [1.35, 1.54] | AUROC: 0.707 [0.692, 0.722] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021656 | PGS000036 (gePS_T2D) |
PSS011742| African Ancestry| 6,019 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.11 [1.0, 1.22] | C-index: 0.641 [0.614, 0.668] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021678 | PGS000036 (gePS_T2D) |
PSS011744| East Asian Ancestry| 1,350 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.23 [0.89, 1.7] | C-index: 0.68 [0.603, 0.756] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM021698 | PGS000036 (gePS_T2D) |
PSS011748| South Asian Ancestry| 5,685 individuals |
PGP000656 | Ritchie SC et al. medRxiv (2024) |Ext.|Pre |
Reported Trait: Incident type 2 diabetes | HR: 1.15 [1.05, 1.25] | C-index: 0.606 [0.583, 0.629] | — | Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting) | — |
| PPM000093 | PGS000040 (GRS_CeD) |
PSS000059| European Ancestry| 2,476 individuals |
PGP000028 | Abraham G et al. PLoS Genet (2014) |
Reported Trait: Coeliac disease | — | AUROC: 0.9 | — | — | — |
| PPM000094 | PGS000040 (GRS_CeD) |
PSS000061| European Ancestry| 1,040 individuals |
PGP000028 | Abraham G et al. PLoS Genet (2014) |
Reported Trait: Coeliac disease | — | AUROC: 0.87 | — | — | — |
| PPM000095 | PGS000040 (GRS_CeD) |
PSS000062| European Ancestry| 1,649 individuals |
PGP000028 | Abraham G et al. PLoS Genet (2014) |
Reported Trait: Coeliac disease | — | AUROC: 0.86 | — | — | — |
| PPM000096 | PGS000040 (GRS_CeD) |
PSS000063| European Ancestry| 2,200 individuals |
PGP000028 | Abraham G et al. PLoS Genet (2014) |
Reported Trait: Coeliac disease | — | AUROC: 0.87 | — | — | — |
| PPM000097 | PGS000040 (GRS_CeD) |
PSS000060| European Ancestry| 10,304 individuals |
PGP000028 | Abraham G et al. PLoS Genet (2014) |
Reported Trait: Coeliac disease | — | AUROC: 0.87 | — | — | — |
| PPM000098 | PGS000040 (GRS_CeD) |
PSS000064| European Ancestry| 1,696 individuals |
PGP000029 | Abraham G et al. Genome Med (2015) |Ext. |
Reported Trait: Coeliac disease | — | AUROC: 0.831 [0.808, 0.85] | — | — | — |
| PPM000099 | PGS000040 (GRS_CeD) |
PSS000065| European Ancestry| 1,237 individuals |
PGP000029 | Abraham G et al. Genome Med (2015) |Ext. |
Reported Trait: Coeliac disease in HLA-DQ2.5 carriers | — | AUROC: 0.669 [0.625, 0.713] | — | — | — |
| PPM000100 | PGS000041 (GRS-DQ2.5-CeD) |
PSS000065| European Ancestry| 1,237 individuals |
PGP000029 | Abraham G et al. Genome Med (2015) |
Reported Trait: Coeliac disease in HLA-DQ2.5 carriers | — | AUROC: 0.718 [0.676, 0.761] | — | — | — |
| PPM000101 | PGS000042 (GRS-DQ2.5-CeD-imputed) |
PSS000065| European Ancestry| 1,237 individuals |
PGP000029 | Abraham G et al. Genome Med (2015) |
Reported Trait: Coeliac disease in HLA-DQ2.5 carriers | — | AUROC: 0.73 [0.687, 0.772] | — | — | — |
| PPM000139 | PGS000055 (PRS_CRC) |
PSS000087| European Ancestry| 61,335 individuals |
PGP000040 | Schmit SL et al. J Natl Cancer Inst (2019) |
Reported Trait: Colorectal cancer | — | — | Familial relative risk explained (%): 11.9 [9.2, 15.5] PRS percentile threshold for Odds Ratio > 2: 95.7 |
age, sex, PCs, PC*study | — |
| PPM000140 | PGS000055 (PRS_CRC) |
PSS000086| East Asian Ancestry| 21,630 individuals |
PGP000040 | Schmit SL et al. J Natl Cancer Inst (2019) |
Reported Trait: Colorectal cancer | — | — | PRS percentile threshold for Odds Ratio > 2: 99.1 | age, sex, PCs, PC*study | — |
| PPM018698 | PGS000055 (PRS_CRC) |
PSS011070| East Asian Ancestry| 332 individuals |
PGP000494 | Ho PJ et al. Elife (2023) |Ext. |
Reported Trait: Colorectal cancer | — | AUROC: 0.65 [0.62, 0.69] | Hazard ratio (HR, high vs low tertile): 2.27 [1.6, 3.21] | age at recruitment | — |
| PPM000194 | PGS000074 (CC_Colorectal) |
PSS000113| European Ancestry| 416,249 individuals |
PGP000050 | Graff RE et al. Nat Commun (2021) |
Reported Trait: Colorectal cancer | OR: 1.37 [1.33, 1.4] | — | — | Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. | Results from meta-analysis of GERA and UKB |
| PPM002040 | PGS000074 (CC_Colorectal) |
PSS001013| European Ancestry| 393,723 individuals |
PGP000186 | Kachuri L et al. Nat Commun (2020) |Ext. |
Reported Trait: Incident colorectal cancer | HR: 1.32 [1.27, 1.37] | AUROC: 0.704 C-index: 0.704 (0.006) |
— | Age at assessment, sex, family history of bowel cancer, genotyping array, PCs(1-15), wasit to hip ratio, cigarette pack years, frequency of processed meat intake (<1 per week vs. ≥1 per week), moderate and/or strenuous physical activity (days per week), alcohol intake | C-index calculated as a weighted average between 1 and 5 years and AUC at 5 years. |
| PPM017164 | PGS000074 (CC_Colorectal) |
PSS010144| European Ancestry| 2,150 individuals |
PGP000443 | Byrne S et al. Int J Epidemiol (2023) |Ext. |
Reported Trait: Colorectal cancer | HR: 1.36 [1.31, 1.42] | — | — | age at baseline, sex (where relevant), assessment centre, 40 principal components of ancestries (PCs), Townsend Index, education, birth location, income, lifestyle index, additional cancer-specific covariates | — |
| PPM000201 | PGS000081 (CC_Oral) |
PSS000120| European Ancestry| 411,577 individuals |
PGP000050 | Graff RE et al. Nat Commun (2021) |
Reported Trait: Oral cavity and pharyngeal cancers | OR: 1.08 [1.02, 1.14] | — | — | Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. | Results from meta-analysis of GERA and UKB |
| PPM002047 | PGS000081 (CC_Oral) |
PSS001020| European Ancestry| 391,479 individuals |
PGP000186 | Kachuri L et al. Nat Commun (2020) |Ext. |
Reported Trait: Incident oral cavity and pharyngeal cancer | HR: 1.11 [1.01, 1.21] | AUROC: 0.702 C-index: 0.686 (0.015) |
— | Age at assessment, sex, genotyping array, PCs(1-15), weekly alcohol intake, cigarettes per day, years of smoking, smoing status (never vs. former vs. current) | C-index calculated as a weighted average between 1 and 5 years and AUC at 5 years. |
| PPM017173 | PGS000081 (CC_Oral) |
PSS010150| European Ancestry| 415 individuals |
PGP000443 | Byrne S et al. Int J Epidemiol (2023) |Ext. |
Reported Trait: Oral cavity and pharyngeal cancers | HR: 1.03 [0.94, 1.14] | — | — | age at baseline, sex (where relevant), assessment centre, 40 principal components of ancestries (PCs), Townsend Index, education, birth location, income, lifestyle index, additional cancer-specific covariates | — |
| PPM000203 | PGS000083 (CC_Pancreas) |
PSS000122| European Ancestry| 411,019 individuals |
PGP000050 | Graff RE et al. Nat Commun (2021) |
Reported Trait: Pancreatic cancer | OR: 1.44 [1.33, 1.55] | — | — | Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. | Results from meta-analysis of GERA and UKB |
| PPM002049 | PGS000083 (CC_Pancreas) |
PSS001022| European Ancestry| 391,491 individuals |
PGP000186 | Kachuri L et al. Nat Commun (2020) |Ext. |
Reported Trait: Incident pancreatic cancer | HR: 1.49 [1.36, 1.62] | AUROC: 0.745 C-index: 0.742 (0.012) |
— | Age at assessment, sex, genotyping array, PCs(1-15), family history of cancer (prostate, breast, lung, bowel), body mass index, cigarette pack-years, smoking status (never vs. former vs. current) | C-index calculated as a weighted average between 1 and 5 years and AUC at 5 years. |
| PPM017171 | PGS000083 (CC_Pancreas) |
PSS010154| European Ancestry| 451 individuals |
PGP000443 | Byrne S et al. Int J Epidemiol (2023) |Ext. |
Reported Trait: Pancreatic cancer | HR: 1.51 [1.38, 1.66] | — | — | age at baseline, sex (where relevant), assessment centre, 40 principal components of ancestries (PCs), Townsend Index, education, birth location, income, lifestyle index, additional cancer-specific covariates | — |
| PPM000404 | PGS000125 (Qi_T2D_2017) |
PSS000232| Hispanic or Latin American Ancestry| 7,746 individuals |
PGP000062 | Qi Q et al. Diabetes (2017) |
Reported Trait: Type 2 Diabetes | — | — | OR (Odds Ratio, per risk allele): 1.07 [1.06, 1.08] | center, age, sex, 5 PCs of ancestry | Covariance matrices corresponding to genetic relatedness (kinship), household, and census block group were included as random effects in the mixed model analysis |
| PPM000439 | PGS000146 (CRC_GRS_27) |
PSS000252| European Ancestry| 3,269 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Distal colon cancer | OR: 1.08 [1.06, 1.11] | — | — | Study, age, endoscopy, family history | — |
| PPM000438 | PGS000146 (CRC_GRS_27) |
PSS000254| European Ancestry| 3,292 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Proximal colon cancer | OR: 1.07 [1.04, 1.1] | — | — | Study, age, endoscopy, family history | — |
| PPM000445 | PGS000146 (CRC_GRS_27) |
PSS000257| European Ancestry| 733 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Colorectal cancer | — | AUROC: 0.56 [0.51, 0.61] | — | Age, endoscopy, family history | — |
| PPM000444 | PGS000146 (CRC_GRS_27) |
PSS000258| European Ancestry| 1,002 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Colorectal cancer | — | AUROC: 0.59 [0.54, 0.64] | — | Age, endoscopy, family history | — |
| PPM000443 | PGS000146 (CRC_GRS_27) |
PSS000255| European Ancestry| 4,573 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Rectal cancer | OR: 1.12 [1.08, 1.15] | — | — | Study, age, endoscopy, family history | — |
| PPM000442 | PGS000146 (CRC_GRS_27) |
PSS000251| European Ancestry| 4,886 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Distal colon cancer | OR: 1.08 [1.05, 1.1] | — | — | Study, age, endoscopy, family history | — |
| PPM000441 | PGS000146 (CRC_GRS_27) |
PSS000253| European Ancestry| 5,530 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Proximal colon cancer | OR: 1.06 [1.03, 1.08] | — | — | Study, age, endoscopy, family history | — |
| PPM000440 | PGS000146 (CRC_GRS_27) |
PSS000256| European Ancestry| 3,167 individuals |
PGP000069 | Hsu L et al. Gastroenterology (2015) |
Reported Trait: Rectal cancer | OR: 1.06 [1.03, 1.09] | — | — | Study, age, endoscopy, family history | — |
| PPM000448 | PGS000147 (CRC21) |
PSS000259| European Ancestry| 4,080 individuals |
PGP000070 | Ibáñez-Sanz G et al. Sci Rep (2017) |
Reported Trait: Colorectal cancer | — | AUROC: 0.63 [0.6, 0.66] | Odds Ratio (OR; per allele): 1.07 [1.04, 1.1] | environmental risk factors ( alcohol consumption, obesity, physical activity, red meat and vegetable consumption, nonsteroidal anti-inflammatory drug use), family history | — |
| PPM000447 | PGS000147 (CRC21) |
PSS000259| European Ancestry| 4,080 individuals |
PGP000070 | Ibáñez-Sanz G et al. Sci Rep (2017) |
Reported Trait: Rectal cancer | — | — | Odds Ratio (OR; per allele): 1.1 [1.06, 1.15] | environmental risk factors ( alcohol consumption, obesity, physical activity, red meat and vegetable consumption, nonsteroidal anti-inflammatory drug use), family history | — |
| PPM000446 | PGS000147 (CRC21) |
PSS000259| European Ancestry| 4,080 individuals |
PGP000070 | Ibáñez-Sanz G et al. Sci Rep (2017) |
Reported Trait: Colon cancer | — | — | Odds Ratio (OR; per allele): 1.06 [1.03, 1.09] | environmental risk factors ( alcohol consumption, obesity, physical activity, red meat and vegetable consumption, nonsteroidal anti-inflammatory drug use), family history | — |
| PPM000449 | PGS000147 (CRC21) |
PSS000259| European Ancestry| 4,080 individuals |
PGP000070 | Ibáñez-Sanz G et al. Sci Rep (2017) |
Reported Trait: Colorectal cancer | — | AUROC: 0.56 [0.54, 0.58] | — | — | — |
| PPM000452 | PGS000148 (CRC63) |
PSS000260| European Ancestry| 5,500 individuals |
PGP000071 | Jeon J et al. Gastroenterology (2018) |
Reported Trait: Colorectal cancer | — | AUROC: 0.59 [0.58, 0.6] | — | age, family history, study, endoscopy history | Risk prediction using Model III (Family History & G-score) |
| PPM000451 | PGS000148 (CRC63) |
PSS000261| European Ancestry| 4,666 individuals |
PGP000071 | Jeon J et al. Gastroenterology (2018) |
Reported Trait: Colorectal cancer | — | AUROC: 0.63 [0.62, 0.64] | — | age, family history, study, endoscopy history, E-score (height, body mass index, education, history of type 2 diabetes mellitus, smoking status, alcohol consumption, regular aspirin use, regular NSAIDs use, smoking pack-years, dietary factors, total-energy, physical activity) | Risk prediction using Model IV (Family history & E-score & G-score) |
| PPM000450 | PGS000148 (CRC63) |
PSS000261| European Ancestry| 4,666 individuals |
PGP000071 | Jeon J et al. Gastroenterology (2018) |
Reported Trait: Colorectal cancer | — | AUROC: 0.59 [0.58, 0.6] | — | age, family history, study, endoscopy history | Risk prediction using Model III (Family History & G-score) |
| PPM000453 | PGS000148 (CRC63) |
PSS000260| European Ancestry| 5,500 individuals |
PGP000071 | Jeon J et al. Gastroenterology (2018) |
Reported Trait: Colorectal cancer | — | AUROC: 0.62 [0.61, 0.63] | — | age, family history, study, endoscopy history, E-score (height, body mass index, education, history of type 2 diabetes mellitus, smoking status, alcohol consumption, regular aspirin use, regular NSAIDs use, regular use of post-menopausal hormones, smoking pack-years, dietary factors, total-energy, physical activity) | Risk prediction using Model IV (Family history & E-score & G-score) |
| PPM000464 | PGS000149 (CRC41) |
PSS000263| European Ancestry| 286,877 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer in individuals with a family history | — | C-index: 0.68 [0.67, 0.7] | — | Wells et al. model (age, diabetes, multi-vitamin usage, family history of colon cancer, years of education, body mass index, alcohol intake, physical activity, non-steroidal anti-inflammatory drug usage, red meat intake, smoking and oestrogen use [women only]) | Fully recalibrated model |
| PPM000463 | PGS000149 (CRC41) |
PSS000263| European Ancestry| 286,877 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer | — | C-index: 0.68 [0.67, 0.7] | — | Wells et al. model (age, diabetes, multi-vitamin usage, family history of colon cancer, years of education, body mass index, alcohol intake, physical activity, non-steroidal anti-inflammatory drug usage, red meat intake, smoking and oestrogen use [women only]) | Fully recalibrated model |
| PPM000459 | PGS000149 (CRC41) |
PSS000262| European Ancestry| 361,543 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer in individuals without a family history | — | C-index: 0.66 [0.62, 0.69] | — | Taylor et al. model (age-specific rates of CRC with estimated relative risks for different degrees of CRC family history) | Fully recalibrated model |
| PPM000458 | PGS000149 (CRC41) |
PSS000262| European Ancestry| 361,543 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer in individuals with a family history | — | C-index: 0.69 [0.67, 0.7] | — | Taylor et al. model (age-specific rates of CRC with estimated relative risks for different degrees of CRC family history) | Fully recalibrated model |
| PPM000457 | PGS000149 (CRC41) |
PSS000262| European Ancestry| 361,543 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer | — | C-index: 0.68 [0.67, 0.7] | — | Taylor et al. model (age-specific rates of CRC with estimated relative risks for different degrees of CRC family history) | Fully recalibrated model |
| PPM000465 | PGS000149 (CRC41) |
PSS000263| European Ancestry| 286,877 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer in individuals without a family history | — | C-index: 0.67 [0.63, 0.71] | — | Wells et al. model (age, diabetes, multi-vitamin usage, family history of colon cancer, years of education, body mass index, alcohol intake, physical activity, non-steroidal anti-inflammatory drug usage, red meat intake, smoking and oestrogen use [women only]) | Fully recalibrated model |
| PPM000462 | PGS000149 (CRC41) |
PSS000263| European Ancestry| 286,877 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer in individuals without a family history | — | C-index: 0.57 [0.53, 0.6] | — | — | — |
| PPM000461 | PGS000149 (CRC41) |
PSS000263| European Ancestry| 286,877 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer in individuals with a family history | — | C-index: 0.56 [0.55, 0.58] | — | — | — |
| PPM000460 | PGS000149 (CRC41) |
PSS000263| European Ancestry| 286,877 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |
Reported Trait: Incident colorectal cancer | — | C-index: 0.57 [0.55, 0.58] | — | — | — |
| PPM000456 | PGS000149 (CRC41) |
PSS000262| European Ancestry| 361,543 individuals |
PGP000072 | Smith T et al. Br J Cancer (2018) |