Trait: longevity

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004300
Description The length of time of an organism's life.
Trait category
Other measurement
Synonyms length of life
Mapped term(s) 2 mapped terms
  • MeSH:D008136
  • SNOMEDCT:111951006

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000906
(PRS-5)
PGP000237 |
Tesi N et al. J Gerontol A Biol Sci Med Sci (2021)
Longevity longevity 330
http://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000906/ScoringFiles/PGS000906.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM002679 PGS000906
(PRS-5)
PSS001184|
European Ancestry|
1,620 individuals
PGP000237 |
Tesi N et al. J Gerontol A Biol Sci Med Sci (2021)
Reported Trait: Survival HR: 0.89 [0.8, 0.98] Age at inclusion, gender, PCs(1-5), and APOE-ε4 carriership (dichotomized) Survival analysis performed in the control samples used to develop the PRS

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS001184 Mean = 10.4 years
Sd = 6.9 years
1,620 individuals,
47.0 % Male samples
Mean = 62.7 years
Sd = 6.4 years
European
(Dutch, NR)
100-plus, LASA, NBB, NTR This dataset overlaps fully with the controls used to develop the score