Trait: red blood cell distribution width

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005192
Description measure of the variation of red blood cell (RBC) volume
Trait category
Hematological measurement
Synonym RDW

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000188
(rdw)
PGP000078 |
Vuckovic D et al. Cell (2020)
Red cell distribution width red blood cell distribution width 546
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000188/ScoringFiles/PGS000188.txt.gz
PGS001152
(GBE_INI30070)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Red blood cell distribution width red blood cell distribution width 10,179
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001152/ScoringFiles/PGS001152.txt.gz
PGS001908
(portability-PLR_erythrocyte_width)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Red blood cell (erythrocyte) distribution width red blood cell distribution width 32,431
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001908/ScoringFiles/PGS001908.txt.gz
PGS002122
(portability-ldpred2_erythrocyte_width)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Red blood cell (erythrocyte) distribution width red blood cell distribution width 543,714
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002122/ScoringFiles/PGS002122.txt.gz
PGS002346
(blood_RBC_DISTRIB_WIDTH.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002346/ScoringFiles/PGS002346.txt.gz
PGS002418
(blood_RBC_DISTRIB_WIDTH.P+T.0.0001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 16,996
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002418/ScoringFiles/PGS002418.txt.gz
PGS002467
(blood_RBC_DISTRIB_WIDTH.P+T.0.001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 36,619
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002467/ScoringFiles/PGS002467.txt.gz
PGS002516
(blood_RBC_DISTRIB_WIDTH.P+T.0.01)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 136,154
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002516/ScoringFiles/PGS002516.txt.gz
PGS002565
(blood_RBC_DISTRIB_WIDTH.P+T.1e-06)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 7,740
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002565/ScoringFiles/PGS002565.txt.gz
PGS002614
(blood_RBC_DISTRIB_WIDTH.P+T.5e-08)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 5,543
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002614/ScoringFiles/PGS002614.txt.gz
PGS002663
(blood_RBC_DISTRIB_WIDTH.PolyFun-pred)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 340,172
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002663/ScoringFiles/PGS002663.txt.gz
PGS002712
(blood_RBC_DISTRIB_WIDTH.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Red Blood Cell Distribution Width red blood cell distribution width 976,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002712/ScoringFiles/PGS002712.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000559 PGS000188
(rdw)
PSS000290|
European Ancestry|
2,314 individuals
PGP000078 |
Vuckovic D et al. Cell (2020)
Reported Trait: Red cell distribution width : 0.07409 sex, age, 10 genetic PCs
PPM000542 PGS000188
(rdw)
PSS000291|
European Ancestry|
39,260 individuals
PGP000078 |
Vuckovic D et al. Cell (2020)
Reported Trait: Red cell distribution width : 0.09519 sex, age, 10 genetic PCs
PPM008482 PGS001152
(GBE_INI30070)
PSS006941|
African Ancestry|
6,139 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Red blood cell distribution width : 0.02633 [0.01865, 0.03401]
Incremental R2 (full-covars): 0.00466
PGS R2 (no covariates): 0.00617 [0.00238, 0.00997]
age, sex, UKB array type, Genotype PCs
PPM008483 PGS001152
(GBE_INI30070)
PSS006942|
East Asian Ancestry|
1,655 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Red blood cell distribution width : 0.06947 [0.04623, 0.09271]
Incremental R2 (full-covars): 0.04028
PGS R2 (no covariates): 0.04714 [0.02754, 0.06675]
age, sex, UKB array type, Genotype PCs
PPM008484 PGS001152
(GBE_INI30070)
PSS006943|
European Ancestry|
24,175 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Red blood cell distribution width : 0.08241 [0.07587, 0.08895]
Incremental R2 (full-covars): 0.07409
PGS R2 (no covariates): 0.0754 [0.06909, 0.0817]
age, sex, UKB array type, Genotype PCs
PPM008485 PGS001152
(GBE_INI30070)
PSS006944|
South Asian Ancestry|
7,520 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Red blood cell distribution width : 0.06357 [0.05312, 0.07403]
Incremental R2 (full-covars): 0.04077
PGS R2 (no covariates): 0.04137 [0.03274, 0.05]
age, sex, UKB array type, Genotype PCs
PPM008486 PGS001152
(GBE_INI30070)
PSS006945|
European Ancestry|
65,638 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Red blood cell distribution width : 0.0852 [0.08117, 0.08923]
Incremental R2 (full-covars): 0.07926
PGS R2 (no covariates): 0.07945 [0.07553, 0.08337]
age, sex, UKB array type, Genotype PCs
PPM010147 PGS001908
(portability-PLR_erythrocyte_width)
PSS009400|
European Ancestry|
19,392 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.3342 [0.3217, 0.3467] sex, age, birth date, deprivation index, 16 PCs
PPM010148 PGS001908
(portability-PLR_erythrocyte_width)
PSS009174|
European Ancestry|
3,996 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.3297 [0.3017, 0.3571] sex, age, birth date, deprivation index, 16 PCs
PPM010149 PGS001908
(portability-PLR_erythrocyte_width)
PSS008728|
European Ancestry|
6,422 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2987 [0.2762, 0.3208] sex, age, birth date, deprivation index, 16 PCs
PPM010150 PGS001908
(portability-PLR_erythrocyte_width)
PSS008502|
Greater Middle Eastern Ancestry|
1,144 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2615 [0.2062, 0.3152] sex, age, birth date, deprivation index, 16 PCs
PPM010151 PGS001908
(portability-PLR_erythrocyte_width)
PSS008280|
South Asian Ancestry|
6,035 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2435 [0.2196, 0.2671] sex, age, birth date, deprivation index, 16 PCs
PPM010152 PGS001908
(portability-PLR_erythrocyte_width)
PSS008057|
East Asian Ancestry|
1,757 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2371 [0.1922, 0.281] sex, age, birth date, deprivation index, 16 PCs
PPM010154 PGS001908
(portability-PLR_erythrocyte_width)
PSS008948|
African Ancestry|
3,680 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.1241 [0.092, 0.1558] sex, age, birth date, deprivation index, 16 PCs
PPM010153 PGS001908
(portability-PLR_erythrocyte_width)
PSS007844|
African Ancestry|
2,328 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.1157 [0.0753, 0.1558] sex, age, birth date, deprivation index, 16 PCs
PPM011832 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS009174|
European Ancestry|
3,996 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.3227 [0.2946, 0.3503] sex, age, birth date, deprivation index, 16 PCs
PPM011831 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS009400|
European Ancestry|
19,392 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.3341 [0.3215, 0.3465] sex, age, birth date, deprivation index, 16 PCs
PPM011833 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS008728|
European Ancestry|
6,422 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2938 [0.2713, 0.3161] sex, age, birth date, deprivation index, 16 PCs
PPM011834 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS008502|
Greater Middle Eastern Ancestry|
1,144 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2528 [0.1972, 0.3067] sex, age, birth date, deprivation index, 16 PCs
PPM011835 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS008280|
South Asian Ancestry|
6,035 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2424 [0.2185, 0.266] sex, age, birth date, deprivation index, 16 PCs
PPM011836 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS008057|
East Asian Ancestry|
1,757 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.2289 [0.1838, 0.273] sex, age, birth date, deprivation index, 16 PCs
PPM011837 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS007844|
African Ancestry|
2,328 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.0986 [0.058, 0.1388] sex, age, birth date, deprivation index, 16 PCs
PPM011838 PGS002122
(portability-ldpred2_erythrocyte_width)
PSS008948|
African Ancestry|
3,680 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Red blood cell (erythrocyte) distribution width Partial Correlation (partial-r): 0.1434 [0.1115, 0.175] sex, age, birth date, deprivation index, 16 PCs
PPM013111 PGS002346
(blood_RBC_DISTRIB_WIDTH.BOLT-LMM)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0257 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013160 PGS002346
(blood_RBC_DISTRIB_WIDTH.BOLT-LMM)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0933 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013209 PGS002346
(blood_RBC_DISTRIB_WIDTH.BOLT-LMM)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.1557 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013258 PGS002346
(blood_RBC_DISTRIB_WIDTH.BOLT-LMM)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0998 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013399 PGS002418
(blood_RBC_DISTRIB_WIDTH.P+T.0.0001)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013448 PGS002418
(blood_RBC_DISTRIB_WIDTH.P+T.0.0001)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0576 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013497 PGS002418
(blood_RBC_DISTRIB_WIDTH.P+T.0.0001)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0994 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013546 PGS002418
(blood_RBC_DISTRIB_WIDTH.P+T.0.0001)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0649 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013595 PGS002467
(blood_RBC_DISTRIB_WIDTH.P+T.0.001)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013644 PGS002467
(blood_RBC_DISTRIB_WIDTH.P+T.0.001)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0099 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013693 PGS002467
(blood_RBC_DISTRIB_WIDTH.P+T.0.001)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0856 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013742 PGS002467
(blood_RBC_DISTRIB_WIDTH.P+T.0.001)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0084 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013791 PGS002516
(blood_RBC_DISTRIB_WIDTH.P+T.0.01)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013840 PGS002516
(blood_RBC_DISTRIB_WIDTH.P+T.0.01)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0008 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013889 PGS002516
(blood_RBC_DISTRIB_WIDTH.P+T.0.01)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0643 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013938 PGS002516
(blood_RBC_DISTRIB_WIDTH.P+T.0.01)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0048 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM013987 PGS002565
(blood_RBC_DISTRIB_WIDTH.P+T.1e-06)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.014 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014036 PGS002565
(blood_RBC_DISTRIB_WIDTH.P+T.1e-06)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0554 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014085 PGS002565
(blood_RBC_DISTRIB_WIDTH.P+T.1e-06)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0938 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014134 PGS002565
(blood_RBC_DISTRIB_WIDTH.P+T.1e-06)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0644 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014183 PGS002614
(blood_RBC_DISTRIB_WIDTH.P+T.5e-08)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0136 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014232 PGS002614
(blood_RBC_DISTRIB_WIDTH.P+T.5e-08)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0506 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014281 PGS002614
(blood_RBC_DISTRIB_WIDTH.P+T.5e-08)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0887 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014330 PGS002614
(blood_RBC_DISTRIB_WIDTH.P+T.5e-08)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0604 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014379 PGS002663
(blood_RBC_DISTRIB_WIDTH.PolyFun-pred)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0343 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_RBC_DISTRIB_WIDTH.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014428 PGS002663
(blood_RBC_DISTRIB_WIDTH.PolyFun-pred)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.1048 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_RBC_DISTRIB_WIDTH.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014477 PGS002663
(blood_RBC_DISTRIB_WIDTH.PolyFun-pred)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.1682 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_RBC_DISTRIB_WIDTH.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014526 PGS002663
(blood_RBC_DISTRIB_WIDTH.PolyFun-pred)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.1097 age, sex, age*sex, assessment center, genotyping array, 10 PCs See blood_RBC_DISTRIB_WIDTH.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014575 PGS002712
(blood_RBC_DISTRIB_WIDTH.SBayesR)
PSS009827|
African Ancestry|
5,990 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0314 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014624 PGS002712
(blood_RBC_DISTRIB_WIDTH.SBayesR)
PSS009828|
East Asian Ancestry|
888 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0864 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014673 PGS002712
(blood_RBC_DISTRIB_WIDTH.SBayesR)
PSS009829|
European Ancestry|
41,837 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.1461 age, sex, age*sex, assessment center, genotyping array, 10 PCs
PPM014722 PGS002712
(blood_RBC_DISTRIB_WIDTH.SBayesR)
PSS009830|
South Asian Ancestry|
7,623 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Red Blood Cell Distribution Width Incremental R2 (full model vs. covariates alone): 0.0986 age, sex, age*sex, assessment center, genotyping array, 10 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009174 3,996 individuals European Poland (NE Europe) UKB
PSS008280 6,035 individuals South Asian India (South Asia) UKB
PSS000290 2,314 individuals European
(French Canadian)
CARTaGENE
PSS000291 39,260 individuals European INTERVAL
PSS008948 3,680 individuals African unspecified Nigeria (West Africa) UKB
PSS008057 1,757 individuals East Asian China (East Asia) UKB
PSS008728 6,422 individuals European Italy (South Europe) UKB
PSS009827 5,990 individuals African unspecified UKB
PSS009828 888 individuals East Asian UKB
PSS009829 41,837 individuals European Non-British European UKB
PSS009830 7,623 individuals South Asian UKB
PSS007844 2,328 individuals African American or Afro-Caribbean Carribean UKB
PSS006941 6,139 individuals African unspecified UKB
PSS006942 1,655 individuals East Asian UKB
PSS006943 24,175 individuals European non-white British ancestry UKB
PSS006944 7,520 individuals South Asian UKB
PSS006945 65,638 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS008502 1,144 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009400 19,392 individuals European UK (+ Ireland) UKB